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  1. Obesity is a major risk factor for type 2 diabetes mellitus (T2DM). A proper anthropometric characterisation of T2DM risk is essential for disease prevention and clinical risk assessement.

    Authors: José María Huerta, María-José Tormo, María-Dolores Chirlaque, Diana Gavrila, Pilar Amiano, Larraitz Arriola, Eva Ardanaz, Laudina Rodríguez, María-José Sánchez, Michelle Mendez, Diego Salmerón, Aurelio Barricarte, Rosana Burgui, Miren Dorronsoro, Nerea Larrañaga, Esther Molina-Montes…
    Citation: BMC Endocrine Disorders 2013 13:7
    Content type: Research article Published on:

  3. Insulin resistance is frequent in human immunodeficiency virus (HIV) infection and may be related to antiretroviral therapy. Cytokines secreted by adipose tissue (adipokines) are linked to insulin sensitivity....

    Authors: Victoria Arama, Catalin Tiliscan, Adrian Streinu-Cercel, Daniela Ion, Raluca Mihailescu, Daniela Munteanu, Adriana Hristea and Stefan Sorin Arama
    Citation: BMC Endocrine Disorders 2013 13:4
    Content type: Research article Published on:

  4. Adrenal insufficiency is a rare and potentially lethal disease if untreated. Several clinical signs and biological markers are associated with glucocorticoid failure but the importance of these factors for dia...

    Authors: Jean-Baptiste Oboni, Pedro Marques-Vidal, François Pralong and Gérard Waeber
    Citation: BMC Endocrine Disorders 2013 13:3
    Content type: Research article Published on:

  6. The mechanism behind parathyroid hormone (PTH) activation of bone remodeling is intimately dependent on the time of exposure of bone cells to hormone levels. Sustained high PTH levels trigger catabolism, while...

    Authors: Maira L Mendonça, Francisco A Pereira, Marcello H Nogueira-Barbosa, Lucas M Monsignore, Sara R Teixeira, Plauto CA Watanabe, Lea MZ Maciel and Francisco JA de Paula
    Citation: BMC Endocrine Disorders 2013 13:1
    Content type: Research article Published on:

  7. Severe hypoglycaemia (SH) is one of the most feared complications of type 1 diabetes (T1DM) with a reported prevalence of nearly 40%. In randomized trials of Multiple Daily Injections (MDI) and Continuous Subc...

    Authors: Stuart Little, Thomas Chadwick, Pratik Choudhary, Cath Brennand, Julia Stickland, Shalleen Barendse, Tolulope Olateju, Lalantha Leelarathna, Emma Walkinshaw, Horng K Tan, Sally M Marshall, Reena M Thomas, Simon Heller, Mark Evans, David Kerr, Daniel Flanagan…
    Citation: BMC Endocrine Disorders 2012 12:33
    Content type: Study protocol Published on:

  9. The use of chromium supplements is widespread for the prevention and treatment of diabetes mellitus but there are conflicting reports on efficacy, possibly reflecting discrepant effects across different popula...

    Authors: Umesh Masharani, Christine Gjerde, Shelley McCoy, Betty A Maddux, Danielle Hessler, Ira D Goldfine and Jack F Youngren
    Citation: BMC Endocrine Disorders 2012 12:31
    Content type: Research article Published on:

  10. Gastroenteropancreatic neuroendocrine neoplasm (GEP-NEN) is the most common type of neuroendocrine tumors accounting for 65–75% of neuroendocrine neoplasms (NENs). Given the fact that there are few studies on ...

    Authors: Yu-hong Wang, Yuan Lin, Ling Xue, Jin-hui Wang, Min-hu Chen and Jie Chen
    Citation: BMC Endocrine Disorders 2012 12:30
    Content type: Research article Published on:

  11. Thyroid hemiagenesis is a rare anomaly, more commonly seen on the left side (ratio 4:1) and in females (ratio 3:1). The first to describe this anomaly was Handfield Jones in 1852.

    Authors: Merima Oruci, Yasuhiro Ito, Marko Buta, Ziv Radisavljevic, Gordana Pupic, Igor Djurisic and Radan Dzodic
    Citation: BMC Endocrine Disorders 2012 12:29
    Content type: Case report Published on:

  12. Structured education programmes are now established as an essential component to assist effective self-management of diabetes. In the case of Type 1 diabetes, the Dose Adjustment For Normal Eating (DAFNE) prog...

    Authors: Jackie Elliott, Julia Lawton, David Rankin, Celia Emery, Mike Campbell, Simon Dixon and Simon Heller
    Citation: BMC Endocrine Disorders 2012 12:28
    Content type: Study protocol Published on:

  13. Vitamin D deficiency is associated with multiple adverse health outcomes including increased morbidity and mortality in the general population and in critically ill patients. However, no randomized controlled ...

    Authors: Karin Amrein, Christian Schnedl, Andrea Berghold, Thomas R Pieber and Harald Dobnig
    Citation: BMC Endocrine Disorders 2012 12:27
    Content type: Study protocol Published on:

  14. In addition to stimulating linear growth in children, growth hormone (GH) influences metabolism and body composition. These effects should be considered when individualizing GH treatment as dose-dependent chan...

    Authors: Ralph Decker, Anders Nygren, Berit Kriström, Andreas FM Nierop, Jan Gustafsson, Kerstin Albertsson-Wikland and Jovanna Dahlgren
    Citation: BMC Endocrine Disorders 2012 12:26
    Content type: Research article Published on:

  15. The Metabolic syndrome (MS) which is a constellation of cardiometabolic risk factors including dyslipidaemia, hypertension, hyperglycaemia, central obesity, and endothelial dysfunction was hitherto relatively ...

    Authors: Mawuli Gyakobo, Albert GB Amoah, De-Anne Martey-Marbell and Rachel C Snow
    Citation: BMC Endocrine Disorders 2012 12:25
    Content type: Research article Published on:

  16. Oxidative stress has been implicated in the development of type 2 diabetes mellitus. Bilirubin is a potent endogenous antioxidant, and coffee is a major source of exogenous antioxidants. Serum gamma-glutamyltr...

    Authors: Zhenjie Wang, Christopher McMonagle, Shinichiro Yoshimitsu, Sanjeev Budhathoki, Makiko Morita, Kengo Toyomura, Keizo Ohnaka, Ryoichi Takayanagi and Suminori Kono
    Citation: BMC Endocrine Disorders 2012 12:24
    Content type: Research article Published on:

  17. Hypoglycaemia is a serious adverse effect of antidiabetic drug therapy. We aimed to determine incidence rates of hypoglycaemia in type-2 diabetic patients and identify predictors of hypoglycaemia when treatmen...

    Authors: Diethelm Tschöpe, Peter Bramlage, Christiane Binz, Michael Krekler, Evelin Deeg and Anselm K Gitt
    Citation: BMC Endocrine Disorders 2012 12:23
    Content type: Research article Published on:

  18. Obesity is a major worldwide health problem. It is commonly observed in Down syndrome individuals than in the general population. The reason for increased risk of obesity in DS is unclear.

    Authors: Sohier Yahia, Reham M EL-farahaty, Amany K El-Hawary, Mona A El-hussiny, Hanaa Abdel-maseih, Faeza El-Dahtory and Abdel-Hady El-Gilany
    Citation: BMC Endocrine Disorders 2012 12:22
    Content type: Research article Published on:

  19. The uncertainties regarding dose similarities between basal long-acting insulin analogues remain. Recent real-world studies indicate dose similarities between insulin detemir and insulin glargine, but further ...

    Authors: Marie Jakobsen, Mette Dalsgaard, Morten Hørmann and Daniél Vega Møller
    Citation: BMC Endocrine Disorders 2012 12:21
    Content type: Research article Published on:

  20. Although consensus guidelines recommend insulin progression among patients with type 2 diabetes (T2DM) who fail to meet glycemic targets over time, many fewer patients are progressed than may benefit. We descr...

    Authors: Jennifer M Polinski, Bradley H Curtis, John D Seeger, Niteesh K Choudhry, Anthony Zagar and William H Shrank
    Citation: BMC Endocrine Disorders 2012 12:20
    Content type: Study protocol Published on:

  21. Increasing evidence suggests the bidirectional interplay between parathyroid hormone and aldosterone as an important mechanism behind the increased risk of cardiovascular damage and bone disease observed in pr...

    Authors: Andreas Tomaschitz, Astrid Fahrleitner-Pammer, Burkert Pieske, Nicolas Verheyen, Karin Amrein, Eberhard Ritz, Katharina Kienreich, Jörg H Horina, Albrecht Schmidt, Elisabeth Kraigher-Krainer, Caterina Colantonio, Andreas Meinitzer and Stefan Pilz
    Citation: BMC Endocrine Disorders 2012 12:19
    Content type: Study protocol Published on:

  22. Assessment of knowledge among resident trainees and nurses is very important since majority of patients admitted in hospital have underlying diabetes which could lead to adverse clinical outcomes if not manage...

    Authors: Asma Ahmed, Abdul Jabbar, Lubna Zuberi, Muhammad Islam and Khusro Shamim
    Citation: BMC Endocrine Disorders 2012 12:18
    Content type: Research article Published on:

  23. The existence of unilateral adrenal hyperplasia (AH) has been considered a rare cause of primary hyperaldosteronism (PA).

    Authors: Helga Agusta Sigurjonsdottir, Mikael Gronowitz, Ove Andersson, Robert Eggertsen, Hans Herlitz, Augustinas Sakinis, Bo Wangberg and Gudmundur Johannsson
    Citation: BMC Endocrine Disorders 2012 12:17
    Content type: Research article Published on:

  24. The association between serum alanine aminotransferase (ALT) levels and hepatic insulin resistance (IR) has been evaluated with the hyperinsulinemic-euglycemic clamp. However, there is no information about the...

    Authors: Miguel Ángel Gómez-Sámano, Daniel Cuevas-Ramos, Roopa Mehta, Hasan Brau-Figueroa, Clara Elena Meza-Arana and Alfonso Gulias-Herrero
    Citation: BMC Endocrine Disorders 2012 12:16
    Content type: Research article Published on:

  25. Diabetes is a major public health problem worldwide. This problem is particularly relevant to the elderly. The prevalence of each condition increase with age. The present study aimed to determine the prevalenc...

    Authors: Sonia Hammami, Sounira Mehri, Said Hajem, Nadia Koubaa, Hala Souid and Mohamed Hammami
    Citation: BMC Endocrine Disorders 2012 12:15
    Content type: Research article Published on:

  27. Mutations in the transcription factor hepatocyte nuclear factor-1-alpha (HNF1A) result in the commonest type of maturity onset diabetes of the young (MODY). HNF1A-MODY carriers have reduced pancreatic beta cel...

    Authors: Siobhan Bacon, Ma Peyh Kyithar, Jasmin Schmid, Syed R Rizvi, Caroline Bonner, Rolf Graf, Jochen HM Prehn and Maria M Byrne
    Citation: BMC Endocrine Disorders 2012 12:13
    Content type: Research article Published on:

  28. To evaluate the U.K. Prospective Diabetes Study (UKPDS) and Framingham risk equations for predicting short-term risk of coronary heart disease (CHD) events among adults with long-standing type 2 diabetes, incl...

    Authors: Shou-En Lu, Gloria L Beckles, Jesse C Crosson, Dorian Bilik, Andrew J Karter, Robert B Gerzoff, Yong Lin, Sonja V Ross, Laura N McEwen, Beth E Waitzfelder, David Marrero, Norman Lasser and Arleen F Brown
    Citation: BMC Endocrine Disorders 2012 12:12
    Content type: Research article Published on:

  30. Severe hypoglycaemia still represents a significant problem in insulin-treated diabetes. Most patients do not experience severe hypoglycaemia often. However, 20% of patients with type 1 diabetes experience rec...

    Authors: Peter Lommer Kristensen, Ulrik Pedersen-Bjergaard, Henning Beck-Nielsen, Kirsten Nørgaard, Hans Perrild, Jens Sandahl Christiansen, Tonny Jensen, Hans-Henrik Parving, Birger Thorsteinsson and Lise Tarnow
    Citation: BMC Endocrine Disorders 2012 12:10
    Content type: Study protocol Published on:

  31. We are hereby investigating for the first time the effect of the association ethinylestradiol30μg-drospirenone 3mg (DRP/EE30μg) plus metformin and weight loss on endothelial status and C-reactive protein (hsCRP) ...

    Authors: Ioana Rada Ilie, Ioan Marian, Teodora Mocan, Razvan Ilie, Lucian Mocan, Ileana Duncea and Carmen Emanuela Pepene
    Citation: BMC Endocrine Disorders 2012 12:9
    Content type: Research article Published on:

  33. There is uncertainty as to which intake of vitamin D is needed to suppress PTH and maintain normal bone metabolism throughout winter at northern latitudes. We aimed to investigate whether four weeks’ daily sup...

    Authors: Kristin Holvik, Ahmed A Madar, Haakon E Meyer, Cathrine M Lofthus and Lars C Stene
    Citation: BMC Endocrine Disorders 2012 12:7
    Content type: Research article Published on:

  34. In patients with both Type 1 and Type 2 diabetes endogenous insulin secretion falls with time which changes treatment requirements, however direct measurement of endogenous insulin secretion is rarely performe...

    Authors: Angus G Jones, Rachel EJ Besser, Beverley M Shields, Timothy J McDonald, Suzy V Hope, Bridget A Knight and Andrew T Hattersley
    Citation: BMC Endocrine Disorders 2012 12:6
    Content type: Research article Published on:

  35. Hypoglycemia is a common complication of diabetes treatment. This paper describes symptoms, predecessors, consequences and medications associated with the first episode of severe hypoglycemia among ACCORD part...

    Authors: Denise E Bonds, Michael E Miller, Jim Dudl, Mark Feinglos, Faramarz Ismail-Beigi, Saul Malozowski, Elizabeth Seaquist, Debra L Simmons and Ajay Sood
    Citation: BMC Endocrine Disorders 2012 12:5
    Content type: Research article Published on:

  36. Pituitary disorders following pregnancy are an important yet under reported clinical entity in the developing world. Conversely, post partum panhypopituitarism has a more devastating impact on women in such se...

    Authors: Faheem G Sheriff, William P Howlett and Kajiru G Kilonzo
    Citation: BMC Endocrine Disorders 2012 12:4
    Content type: Case report Published on:

  37. Animal studies suggest that local adipocyte-mediated activity of the renin-angiotensin-aldosterone system (RAAS) contributes to circulating levels, and may promote the development of obesity-related hypertensi...

    Authors: Conall M O'Seaghdha, Shih-Jen Hwang, Ramachandran S Vasan, Martin G Larson, Udo Hoffmann, Thomas J Wang and Caroline S Fox
    Citation: BMC Endocrine Disorders 2012 12:3
    Content type: Research article Published on:

  38. Hypertriglyceridemia may be associated with important complications. The aim of this study is to estimate the magnitude of association and quality of supporting evidence linking hypertriglyceridemia to cardiov...

    Authors: M Hassan Murad, Ahmad Hazem, Fernando Coto-Yglesias, Svitlana Dzyubak, Shabnum Gupta, Irina Bancos, Melanie A Lane, Patricia J Erwin, Lars Berglund, Tarig Elraiyah and Victor M Montori
    Citation: BMC Endocrine Disorders 2012 12:2
    Content type: Research article Published on:

  40. Sub-Saharan Africa is currently enduring the heaviest global burden of diabetes and diabetes care in such resource poor countries is far below standards. This study aims to describe the gaps in the care of Eth...

    Authors: Esayas K Gudina, Solomon T Amade, Fessahaye A Tesfamichael and Rana Ram
    Citation: BMC Endocrine Disorders 2011 11:19
    Content type: Research article Published on:

  41. Recent evidence suggests that there may be a bidirectional, physiological link between hypogonadism and metabolic syndrome (MetS), and testosterone replacement therapy (TRT) has been shown to improve some symp...

    Authors: Rajib K Bhattacharya, Mohit Khera, Gary Blick, Harvey Kushner, Dat Nguyen and Martin M Miner
    Citation: BMC Endocrine Disorders 2011 11:18
    Content type: Research article Published on:

  42. Older patients with newly diagnosed type 2 diabetes mellitus are less likely to receive antihyperglycaemic therapy compared to their younger counterparts. The purpose of this study was to assess the reasons of...

    Authors: Qiaoyi Zhang, Elizabeth Marrett, Kevin Jameson, Susanne Meiler, Michael J Davies, Larry Radican and Alan J Sinclair
    Citation: BMC Endocrine Disorders 2011 11:17
    Content type: Research article Published on:

  43. We examined the association of biomarkers of inflammation and endothelial dysfunction with diabetes and metabolic syndrome (MetS) in persons from Inner Mongolia.

    Authors: Angela M Thompson, Yonghong Zhang, Weijun Tong, Tan Xu, Jing Chen, Li Zhao, Tanika N Kelly, Chung-Shiuan Chen, Lydia A Bazzano and Jiang He
    Citation: BMC Endocrine Disorders 2011 11:16
    Content type: Research article Published on:

  44. Hyperthyroidism is accompanied by osteoporosis with higher incidence of fracture rates. The present work aimed to study bone status in hyperthyroidism and to elucidate the impact of severity, duration, and eti...

    Authors: El Hadidy M El Hadidy, Mohamed Ghonaim, Soma Sh Abd El Gawad and Mohamed Abou El Atta
    Citation: BMC Endocrine Disorders 2011 11:15
    Content type: Research article Published on:

  45. Patients with acute myocardial infarction and newly detected abnormal glucose regulation have been shown to have a less favourable prognosis compared to patients with normal glucose regulation. The importance ...

    Authors: Eva C Knudsen, Ingebjørg Seljeflot, Michael Abdelnoor, Jan Eritsland, Arild Mangschau, Carl Müller, Harald Arnesen and Geir Ø Andersen
    Citation: BMC Endocrine Disorders 2011 11:14
    Content type: Research article Published on:

  46. Latinos in the United States have a higher prevalence of type 2 diabetes than non-Latino whites, even after controlling for adiposity. Decreased adiponectin is associated with insulin resistance and predicts T...

    Authors: Rocio I Pereira, Cecilia CL Wang, Patrick Hosokawa, L Miriam Dickinson, Michel Chonchol, Mori J Krantz, John F Steiner, Daniel H Bessesen, Edward P Havranek and Carlin S Long
    Citation: BMC Endocrine Disorders 2011 11:13
    Content type: Research article Published on:

  47. Development of type 2 diabetes mellitus (T2DM) is determined by the interactions of genetic and environmental factors. This study was designed to evaluate the possible role of VDR single nucleotide polymorphis...

    Authors: Sakineh Shab-Bidar, Tirang R Neyestani and Abolghassem Djazayery
    Citation: BMC Endocrine Disorders 2011 11:12
    Content type: Study protocol Published on:

  48. Activation of peroxisome proliferator-activated receptor (PPAR)gamma is associated with bone loss and increased fracture risk, while PPARalpha activation seems to have positive skeletal effects. To further exp...

    Authors: Astrid K Stunes, Irene Westbroek, Björn I Gustafsson, Reidar Fossmark, Jan H Waarsing, Erik F Eriksen, Christiane Petzold, Janne E Reseland and Unni Syversen
    Citation: BMC Endocrine Disorders 2011 11:11
    Content type: Research article Published on:

  49. Interferon-α in combination with ribavirin is the current gold standard for treatment of chronic hepatitis C. It is unknown if the development of autoimmune thyroid disease (TD) during treatment confers an imp...

    Authors: Huy A Tran, Tracey L Jones, Robert Gibson and Glenn EM Reeves
    Citation: BMC Endocrine Disorders 2011 11:10
    Content type: Research article Published on:

  50. The once-weekly (QW) formulation of the glucagon-like peptide-1 receptor agonist exenatide has been demonstrated to improve A1C, fasting plasma glucose (FPG), body weight, serum lipid profiles, and blood press...

    Authors: Kristin Taylor, Kate Gurney, Jenny Han, Richard Pencek, Brandon Walsh and Michael Trautmann
    Citation: BMC Endocrine Disorders 2011 11:9
    Content type: Research article Published on:
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BMC Endocrine Disorders

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