Articles

A case report of rhabdomyolysis and osteofascial compartment syndrome in a patient with hypothyroidism and diabetes

Hypothyroidism is frequent and has various forms of muscle involvement. We report the diagnosis and treatment of a case of rhabdomyolysis, bilateral osteofascial compartment syndrome (OCS) of the lower extremi...

Authors: Lijue Ren, Cuiying Wei, Feng Wei, Ruiting Ma, Yan Liu, Yonghong Zhang, Wei Wang, Jing Du, Lin Bai, Yexia Xue and Shaohua Cui

Prediction model for the onset risk of impaired fasting glucose: a 10-year longitudinal retrospective cohort health check-up study

Impaired fasting glucose (IFG) is a prediabetic condition. Considering that the clinical symptoms of IFG are inconspicuous, these tend to be easily ignored by individuals, leading to conversion to diabetes mel...

Authors: Yuqi Wang, Liangxu Wang, Yanli Su, Li Zhong and Bin Peng

Comparison of thyroid function in different emotional states of drug-naïve patients with bipolar disorder

Previous studies have shown that bipolar disorder is closely related to thyroid dysfunction. Psychiatric drugs have a large or small effect on thyroid function, and thyroid hormone levels can also affect the e...

Authors: Shengnan Zhao, Xu Zhang, Yaling Zhou, Hao Xu, Yuwei Li, Yuexin Chen, Bo Zhang and Xueli Sun

Association between diabetes mellitus and anemia among Korean adults according to sex: a cross-sectional analysis of data from the Korea National Health and Nutrition Examination Survey (2010–2016)

There are many conflicting opinions regarding the association between anemia and diabetes mellitus (DM), and the mechanism by which DM influences anemia remains uncertain. Therefore, we aimed to investigate th...

Authors: Mihye Kim, Sook-Hyun Lee, Kyoung Sun Park, Eun-Jung Kim, Sujung Yeo and In-Hyuk Ha

A multicenter, prospective study to observe the initial management of patients with differentiated thyroid cancer in China (DTCC study)

To assess the gaps between the initial management of patients with differentiated thyroid cancer (DTC) in real clinical practice and the recommendations of the 2012 Chinese DTC guidelines.

Authors: Jie Ming, Jing-Qiang Zhu, Hao Zhang, Hui Sun, Jun Wang, Ruo-Chuan Cheng, Lei Xie, Xing-Rui Li, Wen Tian and Tao Huang

Heart failure as a serious complication of iodinated contrast-induced hyperthyroidism: case-report

exposure to iodinated contrast media (ICM) can cause hyperthyroidism, due to disruption of thyroid hormone regulation. Although rare, it can have severe consequences and can lead to fatal complications. Curren...

Authors: Sofie M. Diepenbroek, A. de Jonghe, C. van Rees and E. Seebus

The association of dietary diabetes risk reduction score and its components with risk of metabolic syndrome incident in Tehranian adults

Evidence of possible beneficial effects of dietary diabetes risk reduction score (DDRRS) on reducing the risk of various chronic diseases such as metabolic syndrome (MetS) are limited. This is a prospective, p...

Authors: Parvin Mirmiran, Hossein Farhadnejad, Farshad Teymoori, Golaleh Asghari, Karim Parastouei and Fereidoun Azizi

Association of tooth loss with morbidity and mortality by diabetes status in older adults: a systematic review

This systematic review assesses the association of tooth loss (TL), as the exposure, with morbidity and mortality by diabetes mellitus (DM) status, as the outcome, in older adults.

Authors: Karen Raju, George W. Taylor, Peggy Tahir and Susan Hyde

Deterioration of diabetic nephropathy via stimulating secretion of cytokines by atrial natriuretic peptide

Atrial natriuretic peptide (ANP) is a cardiovascular and metabolic hormone that has been identified recently as being associated with chronic kidney disease (CKD) without diabetes. Cytokines such as interleuki...

Authors: Chenxiao Liu, Qi Li, Xiu Feng, Jian Zhu and Qian Li

The relationship between vitamin D status and islet function in patients with type 2 diabetes mellitus

The aim of the study was to explore the relationship between vitamin D status and islet function in patients with type 2 diabetes mellitus.

Authors: Hang Zhao, Chong Zheng, Miaomiao Zhang and Shuchun Chen

NEUROD1 mutation in an Italian patient with maturity onset diabetes of the young 6: a case report

Maturity Onset Diabetes of the Young (MODY) is a monogenic, autosomal, dominant disease that results in beta-cells dysfunction with consequent hyperglycaemia. It represents a rare form of diabetes (1–2% of all...

Authors: Lucia Brodosi, Bianca Baracco, Vilma Mantovani and Loris Pironi

Lipidomic profiling reveals distinct differences in plasma lipid composition in overweight or obese adolescent students

The relationship between dyslipidemia and obesity has been widely reported, but the global lipid profiles associated with the development of obesity still need to be clarified. An investigation into the associ...

Authors: Ruili Yin, Xiaojing Wang, Kun Li, Ke Yu and Longyan Yang

Predictors of mortality among patients with type 2 diabetes in Jordan

Diabetes Mellitus (DM) is a common metabolic disease associated with increased risk of mortality.

Authors: Fadia Abdallah Mayyas and Khalid Shaker Ibrahim

Glycemic control and neonatal outcomes in women with gestational diabetes mellitus treated using glyburide, metformin, or insulin: a pairwise and network meta-analysis

We aimed to assess the comparative efficiency and safety of the use of glyburide, metformin, and insulin in gestational diabetes mellitus (GDM).

Authors: Dan-Qing Yu, Guan-Xin Xu, Xin-Yuan Teng, Jing-Wei Xu, Liang-Fang Tang, Chun Feng, Jin-Peng Rao, Min Jin and Li-Quan Wang

The relationship between high-density lipoprotein cholesterol (HDL-C) and glycosylated hemoglobin in diabetic patients aged 20 or above: a cross-sectional study

The incidence rate of diabetes is increasing year by year, seriously threatening human health. As a predictor of glycemic control, glycated hemoglobin is reported to be related to various complications and pro...

Authors: Rui Huang, Li Yan and Yuhua Lei

Establishment of reference intervals of monomeric prolactin to identify macroprolactinemia in Chinese patients with increased total prolactin

Macroprolactin is responsible for pseudohyperprolactinemia and is a common pitfall of the prolactin immunoassay. We aimed to determine the frequency of macroprolactinemia in Chinese hyperprolactinemic patients...

Authors: Yao Hu, Jiajin Ni, Buyue Zhang, Wei Cheng, Huating Zhang, Hongying Ye, Lijin Ji, Bin Lu and Ming Guan

Variants of the cry 1 gene may influence the effect of fat intake on resting metabolic rate in women with overweight of obesity: a cross-sectional study

Previous studies have shown that the minor allele (C allele) for Cry 1 rs2287161, may be associated with increased risk of cardiovascular diseases (CVDs). Low resting metabolic rate (RMR) caused by the diet ha...

Authors: Atieh Mirzababaei, Elnaz Daneshzad, Farideh Shiraseb, Sanaz Pourreza, Leila Setayesh, Cain C. T. Clark, Hadith Tangestani, Faezeh Abaj, Habib Yarizadeh and Khadijeh Mirzaei

The susceptibility of SERPINE1 rs1799889 SNP in diabetic vascular complications: a meta-analysis of fifty-one case-control studies

The serine protease inhibitor-1 (SERPINE1) rs1799889 single nucleotide polymorphism (SNP) has been constantly associated with diabetes mellitus (DM) and its vascular complications. The aim of this meta-analysi...

Authors: JingYi Chen, ChuanNan Zhai, ZhiQian Wang, Rui Li, WenJing Wu, Kai Hou, Mohammad Alzogool, Yan Wang and HongLiang Cong

Correction to: Elevated lactate in Mauriac syndrome: still a mystery

Authors: Brice Touilloux, Henri Lu, Belinda Campos-Xavier, Andrea Superti-Furga, Michael Hauschild, Thérèse Bouthors and Christel Tran

A novel heterozygous mutation of CHD7 gene in a Chinese patient with Kallmann syndrome: a case report

Variants of chromodomain helicase DNA binding protein 7 (CHD7) gene are commonly associated with Kallmann syndrome (KS) and account for 5–6% of idiopathic hypogonadotropic hypogonadism (IHH) cases. Here we rep...

Authors: Weiwei Xu, Weibin Zhou, Haiyang Lin, Dan Ye, Guoping Chen, Fengqin Dong and Jianguo Shen

The Mediterranean diet and dietary approach to stop hypertension (DASH)-style diet are differently associated with lipid profile in a large sample of Iranian adults: a cross-sectional study of Shahedieh cohort

The association between the Mediterranean diet (MED) or dietary approach to stop hypertension (DASH) and cardiovascular disease (CVD) risk factors is well-documented. Nevertheless, a consistent relationship wi...

Authors: Monireh Panbehkar-Jouybari, Mehdi Mollahosseini, Amin Salehi-Abargouei, Hossein Fallahzadeh, Masoud Mirzaei and Mahdieh Hosseinzadeh

Late-onset hypophysitis after discontinuation of nivolumab treatment for advanced skin melanoma: a case report

Nivolumab is an anti-programmed cell death protein 1 antibody, typically used as cancer immunotherapy agent. Despite multiple clinical benefits it might cause autoimmune-related side-effects, often involving t...

Authors: Sofia Antoniou, Georgios Bazazo, Ludwig Röckl, Marios Papadakis and Christian Berg

Precocious puberty in Korean girls with and without exposure to endocrine-disrupting chemicals in toy slime: a comparative analysis

Toy slime is popular in Korea, and in parallel, pre-pubertal girls visit hospitals for early pubertal signs. Thus far, numerous studies have investigated the association of endocrine-disrupting chemicals (EDCs...

Authors: Mi Seon Lee, Gi Min Lee, Cheol Woo Ko and Jung Eun Moon

Low physical activity is associated with impaired endothelial function in patients with type 2 diabetes and controls after 5 years of follow-up

The long-term association between physical activity and endothelial function has not previously been investigated in patients with type 2 diabetes. Therefore, we aimed to evaluate the relationship between phys...

Authors: Jonathan Mathias Baier, Kristian Løkke Funck, Liv Vernstrøm, Esben Laugesen and Per Løgstrup Poulsen

Associations between obesity, weight change and decreased renal function in Korean type 2 diabetic patients: a longitudinal follow-up study

We aimed to examine the associations between the risk of decreased renal function, obesity, and weight changes in Korean type 2 diabetic patients with normal renal function.

Authors: Bo-Yeon Kim, Dug-Hyun Choi, Chan-Hee Jung, Ji-Oh Mok and Chul-Hee Kim

The association between overweight/obesity and double diabetes in adults with type 1 diabetes; a cross-sectional study

Double Diabetes (DD), type 1 diabetes (T1DM) + insulin resistance (IR), is associated with increased risk of micro/macro-vascular complications and mortality. Obesity can contribute to the development of DD. T...

Authors: Nathan WP Cantley, Kathryn Lonnen, Ioannis Kyrou, Abd A Tahrani and Hassan Kahal

Association of different pathologic subtypes of growth hormone producing pituitary adenoma and remission in acromegaly patients: a retrospective cohort study

Regarding the inconclusive results of previous investigations, this study aimed to determine the association between pathology, as a possible predictor, with remission outcomes, to know the role of pathology i...

Authors: Maryam Dehghani, Zahra Davoodi, Farahnaz Bidari, Amin Momeni Moghaddam, Davood Khalili, Hooman Bahrami-Motlagh, Elena Jamali, Shahram Alamdari, Farhad Hosseinpanah, Mehdi Hedayati and Majid Valizadeh

The genomic profiling and MAMLD1 expression in human and canines with Cushing’s disease

Cushing’s disease (CD) is defined as hypercortisolemia caused by adrenocorticotropic hormone (ACTH)-secreting pituitary adenomas (corticotroph PA) that afflicts humans and dogs. In order to map common aberrant...

Authors: Andrew Wang, Stewart G. Neill, Scott Newman, Marianna A. Tryfonidou, Adriana Ioachimescu, Michael R. Rossi, Björn P. Meij and Nelson M. Oyesiku

The association between BMI, smoking, drinking and thyroid disease: a cross-sectional study in Wuhan, China

There is no clear conclusion on the relationship between thyroid disease and obesity and lifestyle factors such as smoking and drinking. In this study, we analysed the association of body mass index (BMI), smo...

Authors: Xiao Chen, Juan-juan Wang, Li Yu, Han-yu Wang and Hui Sun

The BAriatic surgery SUbstitution and nutrition (BASUN) population: a data-driven exploration of predictors for obesity

The development of obesity is most likely due to a combination of biological and environmental factors some of which might still be unidentified. We used a machine learning technique to examine the relative im...

Authors: Gudrún Höskuldsdóttir, My Engström, Araz Rawshani, Ville Wallenius, Frida Lenér, Lars Fändriks, Karin Mossberg and Björn Eliasson

Obesity management in polycystic ovary syndrome: disparity in knowledge between obstetrician-gynecologists and reproductive endocrinologists in China

Obesity is associated with the development of polycystic ovary syndrome (PCOS) and contributes substantially to metabolic abnormalities in women with PCOS. The study aimed to describe and compare the practices...

Authors: Ruilin Ma, Ying Zou, Wei Wang, Qingmei Zheng, Ying Feng, Han Dong, Zhangyun Tan, Xiaoqin Zeng, Yinqing Zhao, Yan Deng, Yanfang Wang and Aijun Sun

Comparisons of different exercise interventions on glycemic control and insulin resistance in prediabetes: a network meta-analysis

In order to recommend the optimal type of exercise for type 2 diabetes prevention, different exercise interventions were compared with respect to their effects on glycemic control and insulin resistance.

Authors: Li Huang, Yingjie Fang and Lijun Tang

Effects of naloxone and diazepam on blood glucose levels in tramadol overdose using generalized estimating equation (GEE) model; (an experimental study)

Tramadol is a synthetic opioid and poisoning is increasing around the world day by day. Various treatments are applied for tramadol poisoning. Due to the unknown effects of tramadol poisoning and some of its t...

Authors: Samaneh Nakhaee, Khadijeh Farrokhfall, Ebrahim Miri-Moghaddam, Masoumeh Askari, Alireza Amirabadizadeh, Mohsen Foadoddini and Omid Mehrpour

Rash and cholestatic liver injury caused by methimazole in a woman with Turner syndrome and Graves’s disease: a case report and literature review

Rash and cholestatic liver injury caused by methimazole (MMI) in patients with Turner syndrome (TS) and Graves’s disease (GD) are rarely reported, and there is a paucity of reports on the management of this co...

Authors: Jinhui Zeng, Fangtao Luo, Zhihua Lin, Yinghong Chen, Xiaoyun Wang and Yuanhao Song

Effects of valsartan combined with α-lipoic acid on renal function in patients with diabetic nephropathy: a systematic review and meta-analysis

Diabetic nephropathy (DN) is one of the most serious microvascular complications of diabetes, valsartan and α-lipoic acid alone or in combination has been used for the treatment of patients with DN. However, s...

Authors: Fangfang Sun, Deqi Jiang and Juanjuan Cai

A challenging TSH/GH co-secreting pituitary adenoma with concomitant thyroid cancer; a case report and literature review

Thyroid stimulating hormone (TSH) secreting pituitary adenoma (TSHoma) with coexisting thyroid cancer is extremely rare, and proper treatment of both diseases may pose a unique clinical challenge. When TSHoma ...

Authors: Jee Hee Yoon, Wonsuk Choi, Ji Yong Park, A Ram Hong, Sung Sun Kim, Hee Kyung Kim and Ho-Cheol Kang

Metabolic syndrome and its components are associated with thyroid volume in adolescents

To explore the association between metabolic syndrome (MetS) and its component and thyroid volume in Chinese adolescents, and to compare the detection rate of MetS under the three different diagnostic criteria.

Authors: Yang Xiao, Jingjing Mao, Xiaodong Mao, Qifeng Wang, Xingjia Li, Guofang Chen, Ling Guo, Huaying Huang, Yiming Mu, Shuhang Xu and Chao Liu

Prevalence and associated metabolic factors for thyroid nodules: a cross-sectional study in Southwest of China with more than 120 thousand populations

To explore the prevalence and its associated metabolic factors of thyroid nodules (TNs) among subjects who participated in the physical examinations in Chongqing, China.

Authors: Li Xu, Fanling Zeng, Yutong Wang, Ye Bai, Xuefeng Shan and Lingxi Kong

Dietary protein sources and risk of diabetic nephropathy in women: A case-control study

Several studies have investigated the association between dietary protein and the risk of diabetic nephropathy (DN); however, there is no agreement on the type of dietary protein sources that might increase th...

Authors: Monireh Aziz, Yahya Jalilpiran, Mehdi Nekouimehr, Shaahin Fattahi, Pari Mokhtari, Ahmad Jayedi, Mir Saeed Yekaninejad and Khadijeh Mirzaei

Effects of sleeve gastrectomy on bone mass, microstructure of femurs and bone metabolism associated serum factors in obese rats

Sleeve gastrectomy (SG) is a profoundly effective operation for severe obese patients, but is closely associated with bone mass loss. Previous studies have reported changes of various serum factors which may b...

Authors: Ying Xue, Ran Li, Yong Zhao, Ling Li and Yun Zhou

Elevated lactate in Mauriac syndrome: still a mystery

The Mauriac syndrome was described in 1930 as a peculiar combination of poorly controlled diabetes mellitus type 1, stunted growth and glycogenic hepatopathy. More recently, lactic acidosis was recognized as a...

Authors: Brice Touilloux, Henri Lu, Belinda Campos-Xavier, Andrea Superti-Furga, Michael Hauschild, Thérèse Bouthors and Christel Tran

Vitamin D and thyroid disorders: a systematic review and Meta-analysis of observational studies

The contribution of vitamin D to thyroid disorders has received paramount attention; however, results are mixed. Hence, we designed a systematic review and meta-analysis to obtain a definitive conclusion.

Authors: Sorour Taheriniya, Arman Arab, Amir Hadi, Abdulmannan Fadel and Gholamreza Askari

Association between hypomagnesemia and severity of primary hyperparathyroidism: a retrospective study

The occurrence of hypomagnesemia in patients with primary hyperparathyroidism (PHPT) has been noted previously; however, the association of hypomagnesemia and severity of primary hyperparathyroidism remains un...

Authors: Ding Na, Guo Tao, Liu Shu-Ying, Wang Qin-Yi, Qu Xiao-Li, Li Yong-Fang, Ou Yang-Na, Sheng Zhi-Feng and Yang Yan-Yi

Metformin as a new option in the medical management of breast fibroadenoma; a randomized clinical trial

Fibroadenoma (FA) is the most common benign solid breast mass in women, with no definite method of management. Because fibroadenoma is dependent on female sex hormones and comprises hypertrophic changes at cel...

Authors: Sadaf Alipour, Mahboubeh Abedi, Azin Saberi, Arezoo Maleki-Hajiagha, Firoozeh Faiz, Saeed Shahsavari and Bita Eslami

Thyroid-related ophthalmopathy development in concurrence with growth hormone administration

Thyroid stimulating hormone (TSH) receptor and local infiltrate lymphocytes have been considered as major pathological factors for developing thyroid-related ophthalmopathy. Overexpression of insulin-like grow...

Authors: Shimpei Iwata, Kenji Tsumura, Kenji Ashida, Ichiro Tokubuchi, Mutsuyuki Demiya, Miyuki Kitamura, Hiroyuki Ohshima, Mamiko Yano, Ayako Nagayama, Junichi Yasuda, Munehisa Tsuruta, Seiichi Motomura, Shigeo Yoshida and Masatoshi Nomura

“Slipped capital femoral epiphysis in a 25-year-old hypogonadic man with a large cranial chondroma: causality or coincidence? “

Slipped capital femoral epiphysis (SCFE) is a hip disorder frequently occurring in adolescence. In adults it is rare and so far very few cases have been documented.

Authors: Nadia Sawicka-Gutaj, Waldemar Woźniak, Jakub Naczk, Mateusz Pochylski, Jacek Kruczyński, Bartłomiej Budny, Ewelina Szczepanek-Parulska and Marek Ruchała

Unique three-site compound heterozygous mutation in the WFS1 gene in Wolfram syndrome

Wolfram syndrome (WFS) is a rare autosomal recessive genetic disease whose main cause is mutations in the WFS1 and CISD2 genes. Its characteristic clinical manifestations are diabetes insipidus, diabetes melli...

Authors: Ziyu Ren, Jixiu Yi, Min Zhong, Yunting Wang, Qicong Liu, Xuan Wang, Dongfang Liu and Wei Ren

Areca catechu-(Betel-nut)-induced whole transcriptome changes in a human monocyte cell line that may have relevance to diabetes and obesity; a pilot study

Betel-nut consumption is the fourth most common addictive habit globally and there is good evidence linking the habit to obesity, type 2 diabetes (T2D) and the metabolic syndrome. The aim of our pilot study wa...

Authors: Shirleny R Cardosa, B. William Ogunkolade, Rob Lowe, Emanuel Savage, Charles A Mein, Barbara J Boucher and Graham A Hitman

Multiple endocrine neoplasia type 1 with a frameshift mutation in its gene accompanied by a giant cervical lipoma and multiple fatty deposits in the pancreas: case report

Multiple endocrine

Authors: Yoshiro Fushimi, Shinji Kamei, Fuminori Tatsumi, Junpei Sanada, Masashi Shimoda, Tomohiko Kimura, Atsushi Obata, Shuhei Nakanishi, Kohei Kaku, Tomoatsu Mune and Hideaki Kaneto

Concurrence of overt Cushing’s syndrome and primary aldosteronism accompanied by aldosterone-producing cell cluster in adjacent adrenal cortex: case report

Various adrenal disorders including primary aldosteronism and Cushing’s syndrome lead to the cause of hypertension. Although primary aldosteronism is sometimes complicated with preclinical Cushing’s syndrome, ...

Authors: Yoshiro Fushimi, Fuminori Tatsumi, Junpei Sanada, Masashi Shimoda, Shinji Kamei, Shuhei Nakanishi, Kohei Kaku, Tomoatsu Mune and Hideaki Kaneto