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  1. Despite the evidence available on the adverse impact of gestational diabetes (GDM) and thyroid disorders on developing type 2 diabetes (T2DM), the concurrent influence of these disorders on the incidence of T2...

    Authors: Maryam Zahedi, Elham Kazemian, Fahimeh Ramezani-Tehrani, Maryam Tohidi, Fereidoun Azizi, Davood Khalili, Maryam Rahmati and Atieh Amouzegar

    Citation: BMC Endocrine Disorders 2020 20:150

    Content type: Research article

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  2. A high-molecular-weight form of insulin-like growth factor-2 (IGF-2), known as “big” IGF-2, is occasionally produced by various tumor types, leading to hypoglycemia. Although solitary fibrous tumor (SFT) is a ...

    Authors: Keizo Kaneko, Shojiro Sawada, Chihiro Satake, Keiichi Kondo, Tomohito Izumi, Mamiko Tanaka, Junta Imai, Tetsuya Yamada, Hiroki Katsushima, Fumiyoshi Fujishima and Hideki Katagiri

    Citation: BMC Endocrine Disorders 2020 20:148

    Content type: Case report

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  3. Worldwide, the epidemiological and demographic transitions have resulted in nutrition shift characterized by an increased consumption of high energy fast food products. In just over 3 decades, overweight and o...

    Authors: Pedro Pallangyo, Zabella S. Mkojera, Naairah R. Hemed, Happiness J. Swai, Nsajigwa Misidai, Lucy Mgopa, Smita Bhalia, Jalack Millinga, Theophil L. Mushi, Lucia Kabeya, Aisha Omar, Alice Kaijage, Rydiness Mulashani, Silvia Mosha, Faustina Mwapinga and Mohamed Janabi

    Citation: BMC Endocrine Disorders 2020 20:147

    Content type: Research article

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  4. The risk of surgical site infection has been reported to be higher in patients with poorly controlled diabetes. Since chronic hyperglycemia impairs neutrophil functions, preoperative glycemic control may resto...

    Authors: Daichi Fujimoto, Yuki Nomura, Moritoki Egi, Norihiko Obata and Satoshi Mizobuchi

    Citation: BMC Endocrine Disorders 2020 20:146

    Content type: Research article

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  5. This study tested the association between serum levels of microRNA-486, −146b and -15b and betatrophin in normal and obese children with/without type 2 diabetes mellitus (T2DM).

    Authors: Khalid M. Mohany, Osamah Al rugaie, Osama Al-wutayd, Abdullah Al-Nafeesah and Tahia H. Saleem

    Citation: BMC Endocrine Disorders 2020 20:145

    Content type: Research article

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  6. Congenital adrenal hyperplasia (CAH) with 17α-hydroxylase deficiency is a rare disease; patients often require lifetime cortisol treatment. In this case report, we presented a patient with CAH and 17α-hydroxyl...

    Authors: Chenyu Xiang, Minmin Han, Yi Zhang, Jianhong Yin, Li’e Pei, Jing Yang and Yunfeng Liu

    Citation: BMC Endocrine Disorders 2020 20:144

    Content type: Case report

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  7. Previous studies have shown inconsistent results about the usefulness of bilateral inferior petrosal sinus sampling (BIPSS) in differential diagnosis of adrenocorticotropic hormone (ACTH)-dependent Cushing syn...

    Authors: Hao Wang, Ying Ba, Qian Xing and Run-Ce Cai

    Citation: BMC Endocrine Disorders 2020 20:143

    Content type: Research article

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  8. Primary Empty Sella (PES) syndrome is an increasingly common disorder, mostly diagnosed as an incidental finding during brain imaging scans. We intended to review the clinical management and hormonal profile o...

    Authors: Aishah A. Ekhzaimy, Muhammad Mujammami, Shabana Tharkar, Manahel A. Alansary and Daad Al Otaibi

    Citation: BMC Endocrine Disorders 2020 20:142

    Content type: Research article

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  9. Studies have shown that the response of bone mineral density (BMD) to parathyroidectomy for symptomatic primary hyperparathyroidism (PHPT) is heterogeneous and difficult to predict. However, the independent fa...

    Authors: Shuai Lu, Maoqi Gong, Yejun Zha, Aimin Cui, Chen Chen, Weitong Sun, Kehan Hua, Wei Tian and Xieyuan Jiang

    Citation: BMC Endocrine Disorders 2020 20:141

    Content type: Research article

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  10. The infants born to women who are overweight or obese in pregnancy are at an increased risk of being born macrosomic or large for gestational age. Antenatal dietary and lifestyle interventions have been shown ...

    Authors: Amanda J. Poprzeczny, Jennie Louise, Andrea R. Deussen and Jodie M. Dodd

    Citation: BMC Endocrine Disorders 2020 20:139

    Content type: Research article

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  11. Plasma renin activity (PRA) is generally increased in patients with pheochromocytoma (PCC) due to low circulating plasma volume and activation of β-1 adrenergic receptor signaling. However, there has been no s...

    Authors: Tomoko Yamada, Hidenori Fukuoka, Yusei Hosokawa, Yukiko Odake, Kenichi Yoshida, Ryusaku Matsumoto, Hironori Bando, Yuko Okada, Yushi Hirota, Genzo Iguchi, Wataru Ogawa and Yutaka Takahashi

    Citation: BMC Endocrine Disorders 2020 20:140

    Content type: Research article

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  12. The specific underlying pathogenesis of prolactinoma has not been clarified yet, to the best of our knowledge. p38 mitogen-activated protein kinase (MAPK) signaling including p38α MAPK (MAPK14), p38β (MAPK11),...

    Authors: Qiao-yan Ding, Yu Zhang, Li Ma, Yong-gang Chen, Jin-hu Wu, Hong-feng Zhang and Xiong Wang

    Citation: BMC Endocrine Disorders 2020 20:138

    Content type: Research article

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  13. Diabetes is a serious chronic disease. Medical treatment and good psychosocial support are needed to cope with acute and long-term effects of diabetes. Self-management is a large part of diabetes management, w...

    Authors: Elisabet Nerpin, Eva Toft, Johan Fischier, Anna Lindholm-Olinder and Janeth Leksell

    Citation: BMC Endocrine Disorders 2020 20:137

    Content type: Study protocol

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  14. Previous studies have shown the negative impact of sleep disturbances, specifically insomnia symptoms, on glucose metabolism for people with type 2 diabetes (T2D). People with insomnia symptoms are at risk of ...

    Authors: Mohammed M. Alshehri, Shaima A. Alothman, Aqeel M. Alenazi, Jason L. Rucker, Milind A. Phadnis, John M. Miles, Catherine F. Siengsukon and Patricia M. Kluding

    Citation: BMC Endocrine Disorders 2020 20:136

    Content type: Research article

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  15. Euthyroid sick syndrome (ESS) frequently arises in children admitted with diabetic ketoacidosis/diabetic ketosis (DKA/DK). This study evaluates the interplay of various metabolic factors with occurrence of der...

    Authors: Peng Shao, Shujuan Guo, Guimei Li, Daogang Qin, Sen Li and Ying Luan

    Citation: BMC Endocrine Disorders 2020 20:135

    Content type: Research article

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  16. Diabetic foot ulcers (DFU) are associated with high morbidity and mortality globally. Mortality in patients hospitalized for DFU in Nigeria is unacceptably high. This study was undertaken to determine factors ...

    Authors: Olufunmilayo O. Adeleye, Ejiofor T. Ugwu, Ibrahim D. Gezawa, Innocent Okpe, Ignatius Ezeani and Marcelina Enamino

    Citation: BMC Endocrine Disorders 2020 20:134

    Content type: Research article

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  17. Graves’ disease is the commonest cause of thyrotoxicosis whilst thyrotropin (TSH)-producing pituitary adenomas (thyrotropinomas, TSHomas) are very rare and account for just 1–2% of all pituitary adenomas. Coex...

    Authors: Mark Quinn, Waiel Bashari, Diarmuid Smith, Mark Gurnell and Amar Agha

    Citation: BMC Endocrine Disorders 2020 20:133

    Content type: Case report

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  18. Immune checkpoint inhibitors (ICIs) can induce immune-related adverse events (irAEs) including thyroid dysfunction. There are only a few reports on Graves’ disease induced by ICIs. We report a case of new-onse...

    Authors: Hiroshi Yamada, Fumitaka Okajima, Takeshi Onda, Shunji Fujimori, Naoya Emoto and Hitoshi Sugihara

    Citation: BMC Endocrine Disorders 2020 20:132

    Content type: Case report

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  19. Sympathetic activity and insulin resistance have recently been linked with chronic tendon and musculoskeletal pain. Polycystic ovarian syndrome is linked with insulin resistance and increased sympathetic drive...

    Authors: Jacob Jewson, Elisabeth Lambert, Carolina Sari, Eveline Jona, Soulmaz Shorakae, Gavin Lambert and Jamie Gaida

    Citation: BMC Endocrine Disorders 2020 20:131

    Content type: Research article

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  20. Although important achievements have been done in type 2 diabetes mellitus (T2D) treatment and glycemic control, new strategies may take advantage of non-pharmacological approaches and of other potential deter...

    Authors: Rubén Silva-Tinoco, Teresa Cuatecontzi-Xochitiotzi, Viridiana De la Torre-Saldaña, Enrique León-García, Javier Serna-Alvarado, Arturo Orea-Tejeda, Lilia Castillo-Martínez, Juan G. Gay, David Cantú-de-León and Diddier Prada

    Citation: BMC Endocrine Disorders 2020 20:130

    Content type: Research article

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  21. Diabetic foot is an underestimated and redoubtable diabetes complication. The aims of our study were to assess diabetic foot ulcer risk factors according to International Working Group on the Diabetic Foot (IW...

    Authors: B. Zantour, S. Bouchareb, Z. El Ati, F. Boubaker, W. Alaya, W. Kossomtini and M. H. Sfar

    Citation: BMC Endocrine Disorders 2020 20:128

    Content type: Research article

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  22. Fulminant type 1 diabetes mellitus (FT1D) is a newly established subtype of type 1 diabetes. Its etiology has not been fully elucidated. Several cases with FT1D have exhibited pancreatitis or myocarditis.

    Authors: Fujiko Egashira, Midori Kawashima, Ai Morikawa, Minami Kosuda, Hisamitsu Ishihara and Kentaro Watanabe

    Citation: BMC Endocrine Disorders 2020 20:127

    Content type: Case report

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  23. Acromegaly is a rare, chronic and severe disease. Drug therapy including somatostatin analogues (SAs), dopamine receptor agonists and growth hormone receptor antagonists (pegvisomant, PEG) are commonly used to...

    Authors: Lingyun Ma, Daohuang Luo, Ting Yang, Songtao Wu, Min Li, Chaoyang Chen, Shuang Zhou, Lingyue Ma, Ye Wu, Ying Zhou and Yimin Cui

    Citation: BMC Endocrine Disorders 2020 20:126

    Content type: Research article

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  24. Diabetes is a leading cause of Medicare spending; predicting which individuals are likely to be costly is essential for targeting interventions. Current approaches generally focus on composite measures, short ...

    Authors: Julie C. Lauffenburger, Mufaddal Mahesri and Niteesh K. Choudhry

    Citation: BMC Endocrine Disorders 2020 20:125

    Content type: Research article

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  25. Modern imaging plays a central role in the care of obese patients, and there is an integral focus on its use and accessibility in individuals who have alterations of various in various organs. The objective in...

    Authors: Alejandra Martínez Coria, Norma Angélica Estrada-Cruz, María Inés Pérez Ordoñez, Daniel H. Montes-Cortes and Leticia Manuel-Apolinar

    Citation: BMC Endocrine Disorders 2020 20:124

    Content type: Research article

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  26. Type 1 Diabetes (T1D) is a T cell-mediated autoimmune disorder caused by the destruction of insulin-secreting cells. B7-H3 (CD276) plays a vital role in T cell response. However, B7-H3 expression and its clini...

    Authors: Sisi Ding, Yimei Shan, Lili Sun, Sicheng Li, Rong Jiang, Xin Chang, Ziyi Huang, Jing Sun, Cuiping Liu, Chen Fang and Xueguang Zhang

    Citation: BMC Endocrine Disorders 2020 20:123

    Content type: Research article

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  27. The prevalence of type 2 diabetes mellitus (T2DM) is expected to increase from 7.7% in 2017 to 8.4% in 2045 worldwide. Diabetes complications contribute to morbidity and mortality. To evaluate whether the diab...

    Authors: Hyunju Yoo, Eunjung Choo and Sukhyang Lee

    Citation: BMC Endocrine Disorders 2020 20:122

    Content type: Research article

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  28. The association between the polymorphisms in the vitamin D receptor (VDR) gene and the risk of type 1 diabetes mellitus (T1DM) has been evaluated in several studies. However, the findings were inconclusive. Thus,...

    Authors: Na Zhai, Ramtin Bidares, Masoud Hassanzadeh Makoui, Saeed Aslani, Payam Mohammadi, Bahman Razi, Danyal Imani, Mohammad Yazdchi and Haleh Mikaeili

    Citation: BMC Endocrine Disorders 2020 20:121

    Content type: Research article

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  29. Basedow’s disease and Hashimoto’s thyroiditis are autoimmune thyroid disorders and usually diagnosed with elevation of serum autoimmune antibodies. Thyrotropin receptor antibodies (TRAb) and/or thyroid-stimula...

    Authors: Megumi Horiya, Takatoshi Anno, Fumiko Kawasaki, Yuichiro Iwamoto, Shintaro Irie, Yasumasa Monobe, Koichi Tomoda, Kohei Kaku, Shuhei Nakanishi and Hideaki Kaneto

    Citation: BMC Endocrine Disorders 2020 20:120

    Content type: Case report

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  30. The growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis is critical for the regulation of children’s growth and development. Serum IGF-1 concentrations are usually low in individuals with idiopathic sh...

    Authors: Qianqian Zhao, Mei Zhang, Baolan Ji, Yuntian Chu, Hui Pan, Wenhua Yan and Bo Ban

    Citation: BMC Endocrine Disorders 2020 20:119

    Content type: Research article

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  31. The escalating prevalence of adrenal incidentaloma (AI) has been associated with the improvement of radiologic techniques and widespread imaging in aging population. It is currently unclear whether patients wi...

    Authors: Ana Podbregar, Andrej Janez, Katja Goricar and Mojca Jensterle

    Citation: BMC Endocrine Disorders 2020 20:118

    Content type: Research article

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  32. Acromegaly patients managed on Somatostatin receptor ligands (SRLs), the most common first-line pharmacotherapy for acromegaly, may still experience acromegaly symptoms such as headache, sweating, fatigue, sof...

    Authors: Eliza B. Geer, Jill Sisco, Daphne T. Adelman, William H. Ludlam, Asi Haviv, Shuqian Liu, Susan D. Mathias, Dana Gelbaum and Lizheng Shi

    Citation: BMC Endocrine Disorders 2020 20:117

    Content type: Research article

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  33. Cushing’s syndrome has been described as a complex endocrine disorder characterized with high cortisol concentration. Correct and early diagnosis of Cushing’s syndrome is challenging. According to the latest g...

    Authors: Huiwen Tan, Dawei Chen, Yerong Yu, Kai Yu, Weiming He, Bowen Cai, Su Jiang, Ying Tang, Nanwei Tong and Zhenmei An

    Citation: BMC Endocrine Disorders 2020 20:116

    Content type: Case report

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  34. Primary aldosteronism (PA) increases the risk of cardiovascular morbidity, including stroke, coronary artery disease, atrial fibrillation, and heart failure. The relationship between primary aldosteronism and ...

    Authors: Ying Zhang, Fang Luo, Peng Fan, Xu Meng, Kunqi Yang and Xianliang Zhou

    Citation: BMC Endocrine Disorders 2020 20:115

    Content type: Case report

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  35. We investigated whether the contralateral suppression index in aldosterone-producing adrenal adenoma could be used as a diagnostic criterion when catheterization in either right or left adrenal vein fails or w...

    Authors: Jeongmin Lee, Borami Kang, Jeonghoon Ha, Min-Hee Kim, Byungil Choi, Tae-Ho Hong, Moo IL Kang and Dong-Jun Lim

    Citation: BMC Endocrine Disorders 2020 20:114

    Content type: Research article

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  36. Colorectal cancer (CRC), which is related with insulin resistance, is a one of the most common cancers. Triglyceride-glucose index (TyG index) was made for a marker of insulin resistance. We conducted the inve...

    Authors: Takuro Okamura, Yoshitaka Hashimoto, Masahide Hamaguchi, Akihiro Obora, Takao Kojima and Michiaki Fukui

    Citation: BMC Endocrine Disorders 2020 20:113

    Content type: Research article

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  37. Albuminuria is the early manifestation of the pathogenesis of diabetic nephropathy (DN). The current study was to investigate the relationship of pulmonary function with albuminuria in type 2 diabetic patients...

    Authors: Yun-Yun He, Zhe Chen, Xiang-Yang Fang, Jing Chang, Yong Lu and Xiao-Juan Wang

    Citation: BMC Endocrine Disorders 2020 20:112

    Content type: Research article

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  38. Marital status proves to be an independent prognostic factor in a variety of cancers. However, its prognostic impact on gastric neuroendocrine neoplasms (G-NEN) has not been investigated.

    Authors: Yu-Jie Zhou, Xiao-Fan Lu, Kenneth I. Zheng, Qi-Wen Wang, Jin-Nan Chen, Qing-Wei Zhang, Fang-Rong Yan and Xiao-Bo Li

    Citation: BMC Endocrine Disorders 2020 20:111

    Content type: Research article

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  39. Some studies have shown that a high level of bilirubin is a protective factor against metabolic syndrome (MS), while a high level of transaminase is a risk factor for MS. However, the existing results are inco...

    Authors: Hao Hao, Heng Guo, Ru-lin Ma, Yi-zhong Yan, Yun-hua Hu, Jiao-long Ma, Xiang-hui Zhang, Xin-ping Wang, Kui Wang, La-ti Mu, Yan-peng Song, Jing-yu Zhang, Jia He and Shu-xia Guo

    Citation: BMC Endocrine Disorders 2020 20:110

    Content type: Research article

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  40. Type 2 diabetes mellitus (T2D) is the most frequent type of diabetes. It has a multifactorial etiology, affecting millions of people worldwide. Ghrelin gene (GHRL) encodes the ghrelin peptide, which promotes food...

    Authors: Edgar Alfonso Rivera-León, Mara Anaís Llamas-Covarrubias, Sergio Sánchez-Enríquez, Erika Martínez-López, Mercedes González-Hita and Iris Monserrat Llamas-Covarrubias

    Citation: BMC Endocrine Disorders 2020 20:109

    Content type: Research article

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  41. Zonulin is a biomarker of impaired intestinal permeability, which has been associated with various disorders. The primary aim was to study serum zonulin (s-zonulin) in individuals with morbid obesity before an...

    Authors: Martin Aasbrenn, Stian Lydersen and Per G Farup

    Citation: BMC Endocrine Disorders 2020 20:108

    Content type: Research article

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  42. Some previous studies have reported inconsistent results on the association between alcohol intake and diabetic retinopathy (DR) risk. This study aimed to evaluate the potential effects of alcohol intake on su...

    Authors: Chen Chen, Zhaojun Sun, Weigang Xu, Jun Tan, Dan Li, Yiting Wu, Ting Zheng and Derong Peng

    Citation: BMC Endocrine Disorders 2020 20:106

    Content type: Research article

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  43. Statins are the first-line pharmaceutical agent in the management of hypercholesterolemia and cardiovascular (CV) risk reduction, and the most commonly prescribed class of drugs worldwide. Studies describing C...

    Authors: Ezra S. Hornik, Anne E. Altman-Merino, Andrew W. Koefoed, Kayla M. Meyer, Isabella B. Stone, Jessica A. Green, Gordon H. Williams, Gail K. Adler and Jonathan S. Williams

    Citation: BMC Endocrine Disorders 2020 20:105

    Content type: Study protocol

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  44. Recently, CaMKIV has been identified as a potential regulator of skeletal muscle glucose metabolism, it can also affect insulin gene expression in pancreas. However, its effects on adipose insulin resistance h...

    Authors: Jiali Liu, Ruihua Yang, Hao Meng, Ting Zhou and Qian He

    Citation: BMC Endocrine Disorders 2020 20:104

    Content type: Research article

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  45. To evaluate the association between high-sensitivity C-reactive protein (hsCRP) and erythrocyte sedimentation rate (ESR), and diabetic kidney disease (DKD) in patients with type 2 diabetes mellitus (T2DM).

    Authors: Shizhe Guo, Meng Wang, Yifei Yu, Yeping Yang, Fangfang Zeng, Fei Sun, Qin Li, Min He, Yiming Li, Jie Wen, Wei Gong and Zhaoyun Zhang

    Citation: BMC Endocrine Disorders 2020 20:103

    Content type: Research article

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  46. The associations between sociodemographic factors and HbA1c variability in type 2 diabetes are not yet established. Examining group differences in HbA1c variability may help identify patient characteristics re...

    Authors: Emelia Mellergård, Per Johnsson and Frida Eek

    Citation: BMC Endocrine Disorders 2020 20:102

    Content type: Research article

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  47. Anti-Müllerian hormone (AMH) is now considered the best serum biomarker of ovarian reserve, while basal sex hormones are classic markers used for assessing ovarian reserve. The interaction between AMH and sex ...

    Authors: Ping-Ping Lv, Min Jin, Jin-Peng Rao, Jian Chen, Li-Quan Wang, Chang-Chang Huang, Song-Qing Yang, Qiu-Ping Yao, Lei Feng, Jin-Ming Shen and Chun Feng

    Citation: BMC Endocrine Disorders 2020 20:101

    Content type: Research article

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