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  1. Content type: Case report

    Charcot neuropathic osteoarthropathy (CNO) is one of the most devastating complications of neuropathy in patients with diabetes. Establishing diagnosis of CNO is difficult, due to the lack of clear clinical an...

    Authors: C. V. Loupa, E. Meimeti, A. Kokas, E. D. Voyatzoglou and A. Donou

    Citation: BMC Endocrine Disorders 2019 19:96

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  2. Content type: Research article

    Cholecystectomy, central obesity, and insulin resistance (IR) are established risk factors for nonalcoholic fatty liver disease (NAFLD). We aimed to examine the relative contributions and combined association ...

    Authors: Wenzhu Yue, Xingxing Sun and Tingting Du

    Citation: BMC Endocrine Disorders 2019 19:95

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  3. Content type: Research article

    Acromegaly is highly associated with thyroid disorders. However, the clinical characteristics of thyroid nodules in individuals with acromegaly who present with thyroid diseases have not been completely elucid...

    Authors: Dianshuang Xu, Bolin Wu, Xiaoju Li, Yunjiu Cheng, Dubo Chen, Yuefeng Fang, Qiu Du, Zhiyong Chen and Xiaodong Wang

    Citation: BMC Endocrine Disorders 2019 19:94

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  4. Content type: Research article

    Obese women with polycystic ovary syndrome (PCOS) may face additional barriers in achieving weight loss. We aimed to compare the effects of the hypocaloric low glycemic index (LGI) diet on anthropometric varia...

    Authors: Farnaz Shishehgar, Parvin Mirmiran, Maryam Rahmati, Maryam Tohidi and Fahimeh Ramezani Tehrani

    Citation: BMC Endocrine Disorders 2019 19:93

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  5. Content type: Case report

    Hypertriglyceridemia is often observed as the result of lipid abnormality and frequently associated with other lipid and metabolic disorders. Aggravation of hypertriglyceridemia is caused by various conditions...

    Authors: Shintaro Irie, Takatoshi Anno, Fumiko Kawasaki, Ryo Shigemoto, Shuhei Nakanishi, Kohei Kaku and Hideaki Kaneto

    Citation: BMC Endocrine Disorders 2019 19:92

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  6. Content type: Research article

    In 2015 approximately 5.0 million people were estimated to have died from diabetes. Poor glycemic control is the most determinant of diabetes-related complication and death. The percentage of patients whose bl...

    Authors: Yitagesu Mamo, Fekede Bekele, Tadesse Nigussie and Ameha Zewudie

    Citation: BMC Endocrine Disorders 2019 19:91

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  7. Content type: Research article

    Endothelial cell-specific molecule-1 (ESM-1) is a biomarker associated with tumor progression in pituitary adenoma. We specifically focused on one type of pituitary adenoma, namely null cell adenoma (NCA) and ...

    Authors: Shousen Wang, Zhifeng Wu, Liangfeng Wei and Jianhe Zhang

    Citation: BMC Endocrine Disorders 2019 19:90

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  8. Content type: Research article

    Diabetes-related kidney disease is associated with end-stage renal disease and mortality, but opportunities remain to quantify its association with cardiovascular and non-cardiovascular morbidity outcomes.

    Authors: James B. Wetmore, Suying Li, Thanh G. N. Ton, Yi Peng, Michael K. Hansen, Cheryl Neslusan, Ralph Riley, Jiannong Liu and David T. Gilbertson

    Citation: BMC Endocrine Disorders 2019 19:89

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  9. Content type: Research article

    Glycosylated hemoglobin (HbA1c) has a detrimental impact on the myocardium with left ventricular (LV) diastolic dysfunction. Obesity is a risk factor of type 2 diabetes. To understand the relationships between...

    Authors: Xin Zuo, Xueting Liu, Runtian Chen, Huiting Ou, Jiabao Lai, Youming Zhang and Dewen Yan

    Citation: BMC Endocrine Disorders 2019 19:88

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  10. Content type: Research article

    Subjects with prediabetes are at increased risk of future T2DM and cardiovascular disease (CVD) compared to NGT individuals. The OGTT (FPG = 100–125 and 2 h-PG = 140–199 mg/dl) and HbA1c 5.7–6.4% have been use...

    Authors: Saadallah Iskandar, Ayman Migahid, Dalia Kamal, Osama Megahed, Ralph A. DeFronzo, Mahmoud Zirie, Amin Jayyousi, Mahmood Al Jaidah and Muhammad Abdul-Ghani

    Citation: BMC Endocrine Disorders 2019 19:87

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  11. Content type: Case report

    The diagnosis of subacute thyroiditis (SAT) is based mainly on the presence of painful thyroid goitre and a significant increase in erythrocyte sedimentation rate (ESR). Proceeding according to these diagnosti...

    Authors: Magdalena Stasiak, Renata Michalak and Andrzej Lewinski

    Citation: BMC Endocrine Disorders 2019 19:86

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  12. Content type: Research article

    Older patients with type 2 diabetes mellitus represent a heterogeneous group in terms of metabolic profile. It makes glucose-lowering-therapy (GLT) complex to manage, as it needs to be individualised according...

    Authors: Antoine CHRISTIAENS, Michel P. HERMANS, Benoit BOLAND and Séverine HENRARD

    Citation: BMC Endocrine Disorders 2019 19:85

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  13. Content type: Research article

    In patients with diabetes mellitus, the urinary microalbumin-to-urine creatinine ratio (UACR) can not only predict the occurrence of diabetic nephropathy but also can be a risk factor for cardiovascular diseas...

    Authors: Juan Xie, Xiaoqing Wang, Yiyuan Zhang, Hailun Li, Yong Xu and Donghui Zheng

    Citation: BMC Endocrine Disorders 2019 19:84

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  14. Content type: Research article

    Thyroid dysfunction is one of the prevalent endocrine disorders. The relationship between lifestyle factors and thyroid dysfunction was not clear and some of the factors seemed paradoxical.

    Authors: Yanling Huang, Liangchun Cai, Yuanyuan Zheng, Jinxing Pan, Liantao Li, Liyao Zong, Wei Lin, Jixing Liang, Huibin Huang, Junping Wen and Gang Chen

    Citation: BMC Endocrine Disorders 2019 19:83

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  15. Content type: Case report

    Primary hyperparathyroidism (PHPT), which is mostly caused by a parathyroid adenoma, is fairly common in postmenopausal women but is relatively rare in pregnant women. PHPT-induced pancreatitis during pregnanc...

    Authors: Jun Yang, Meng-jie Dong and Feng Chen

    Citation: BMC Endocrine Disorders 2019 19:82

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  16. Content type: Research article

    Elderly patients with type 2 diabetes mellitus (T2DM) experience fractures more frequently than elderly individuals without diabetes. Fractures requiring hospitalization greatly affect quality of life, and alt...

    Authors: Takeshi Horii, Makiko Iwasawa, Yusuke Kabeya, Jyunichi Shimizu and Koichiro Atsuda

    Citation: BMC Endocrine Disorders 2019 19:81

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  17. Content type: Case report

    Myasthenia gravis (MG) is the most common disorder of neuromuscular transmission, and it is typified by fluctuating degrees and variable combinations of weakness in the ocular, bulbar, limb, and respiratory mu...

    Authors: Mi-Chu Lin, Ming-Hsien Tsai, Jyh-Gang Leu and Yu-Wei Fang

    Citation: BMC Endocrine Disorders 2019 19:80

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  18. Content type: Research article

    Traditionally Type 2 Diabetes Mellitus (T2DM) was associated with older age, but is now being increasingly diagnosed in younger populations due to the increasing prevalence of obesity and inactivity. We aimed ...

    Authors: Laura J. Gray, Emer M. Brady, Olatz Albaina, Charlotte L. Edwardson, Deirdre Harrington, Kamlesh Khunti, Joanne Miksza, João Filipe Raposo, Ellesha Smith, Andriani Vazeou, Itziar Vergara, Susann Weihrauch-Blüher and Melanie J. Davies

    Citation: BMC Endocrine Disorders 2019 19:79

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  19. Content type: Study protocol

    Hypoglycaemia, especially nocturnal, remains the main limiting factor of achieving good glycaemic control in type 1 diabetes.

    Authors: Rikke Mette Agesen, Amra Ciric Alibegovic, Henrik Ullits Andersen, Henning Beck-Nielsen, Peter Gustenhoff, Troels Krarup Hansen, Christoffer Hedetoft, Tonny Jensen, Claus Bogh Juhl, Susanne Søgaard Lerche, Kirsten Nørgaard, Hans-Henrik Parving, Lise Tarnow, Birger Thorsteinsson and Ulrik Pedersen-Bjergaard

    Citation: BMC Endocrine Disorders 2019 19:78

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  20. Content type: Research article

    Chronic inflammation has been associated with dysglycemia among people living with HIV (PLHIV). There is however, limited data regarding this phenomenon in sub-Sahara Africa (SSA). Therefore we assessed the le...

    Authors: Lilian Nkinda, Kirtika Patel, Benson Njuguna, Jean Pierre Ngangali, Peter Memiah, George M. Bwire, Mtebe V. Majigo, Mucho Mizinduko, Sonak D. Pastakia and Eligius Lyamuya

    Citation: BMC Endocrine Disorders 2019 19:77

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  21. Content type: Research article

    Sarcopenic obesity, central obesity combined with decreased skeletal muscle mass, is identified to be associated with metabolic syndrome and cardiovascular diseases; however, its role in the occurrence of non-...

    Authors: Xiaoyou Su, Jing Xu and Chao Zheng

    Citation: BMC Endocrine Disorders 2019 19:76

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  22. Content type: Research article

    To investigate any associations between blood glucose (BG) and lipid levels in patients with different glucose tolerance statuses, including type 2 diabetes (T2DM) and impaired glucose regulation (IGR) cases a...

    Authors: Shujin Wang, Guohong Li, Hong Zuo, Hua Yang, Lei Ma, Jia Feng, Yu Niu, Liming Ma, Songfang Liu, Ting Qi and Xufeng Liu

    Citation: BMC Endocrine Disorders 2019 19:75

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  23. Content type: Study protocol

    Type 2 Diabetes Mellitus (T2DM) has become an endemic disease. A number of interrelated factors increase the risk of the onset of T2DM, however much of the pathogenesis of the disease is associated with lifest...

    Authors: Linda Cloete, Brett G. Mitchell and Darren Morton

    Citation: BMC Endocrine Disorders 2019 19:74

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  24. Content type: Research article

    Several studies have indicated that inflammatory markers were associated with the risk of mild cognitive impairment (MCI) in type 2 diabetes (T2D). Serum folate was related to MCI as well as inflammation. Howe...

    Authors: Miaoyan Zheng, Baocheng Chang, Liqiang Tian, Chunyan Shan, Hui Chen, Yuxia Gao, Guowei Huang and Meilin Zhang

    Citation: BMC Endocrine Disorders 2019 19:73

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  25. Content type: Research article

    Further knowledge about the pubertal development mode of girls with Turner syndrome (TS) who have undergone hormone replacement therapy (HRT) is beneficial to the proposal of an optimal HRT regimen. This study...

    Authors: Song Guo, Jun Zhang, Yanhong Li, Huamei Ma, Qiuli Chen, Hongshan Chen and Minlian Du

    Citation: BMC Endocrine Disorders 2019 19:72

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  26. Content type: Case report

    Metabolic encephalopathy is a rare but potentially devastating complication of diabetic ketoacidosis (DKA). This case highlights the dramatic cognitive decline of a young man due to metabolic encephalopathy co...

    Authors: Maria Tomkins, Richard McCormack, Karen O’Connell, Amar Agha and Áine Merwick

    Citation: BMC Endocrine Disorders 2019 19:71

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  27. Content type: Research article

    Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in young women and increases risk of cardiovascular and metabolic disease, and infertility. Women with PCOS share many characteristics com...

    Authors: Laura E. McBreairty, Philip D. Chilibeck, Julianne J. Gordon, Donna R. Chizen and Gordon A. Zello

    Citation: BMC Endocrine Disorders 2019 19:70

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  28. Content type: Research article

    To assess the association between cardiorespiratory fitness (CRF) and weight changes in treatment seeking patients with severe obesity who underwent a 1-year intensive lifestyle intervention (ILI) program.

    Authors: Jarle Berge, Øyvind Støren, Jens K. Hertel, Espen Gjevestad, Milada Cvancarova Småstuen and Jøran Hjelmesæth

    Citation: BMC Endocrine Disorders 2019 19:69

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  29. Content type: Case report

    Endogenous Cushing’s syndrome, a rare endocrine disorder, characterised by chronic cortisol hypersecretion, results in neuropsychiatric disturbances and in cognitive deficits, which are only partially reversib...

    Authors: Malgorzata Monika Brzozowska, Sacha Kepreotis, Fiona Tsang and Sully Xiomara Fuentes- Patarroyo

    Citation: BMC Endocrine Disorders 2019 19:68

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  30. Content type: Research article

    This study aimed to examine the associations between gender and the prevalence of metabolic syndrome (MS) components among Korean adults by age and body mass index (BMI) subgroups.

    Authors: Young-Mo Yang, Byung-Cheul Shin, Chihyoung Son and In-Hyuk Ha

    Citation: BMC Endocrine Disorders 2019 19:67

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  31. Content type: Research article

    The aim of the study was to estimate and compare the 8-year cumulative incidence of diabetes mellitus (DM) among Sami and non-Sami inhabitants of rural districts in Northern Norway.

    Authors: Ali Naseribafrouei, Bent Martin Eliassen, Marita Melhus, Johan Svartberg and Ann Ragnhild Broderstad

    Citation: BMC Endocrine Disorders 2019 19:66

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  32. Content type: Research article

    The Captopril challenge test (CCT) is an easy-conduct confirmatory test for diagnosing primary aldosteronism (PA). Guidelines show that plasma aldosterone is normally suppressed by captopril (> 30%) in primary...

    Authors: Ke-ying Zhu, Yan Zhang, Wen-jing Zhang, Hong-yun Li, Wen-huan Feng, Da-long Zhu and Ping Li

    Citation: BMC Endocrine Disorders 2019 19:65

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  33. Content type: Correspondence

    For patients with type 2 diabetes (T2D), cardiovascular disease (CVD) is the single most common cause of mortality. In 2008 and 2012, the Federal Drug Administration (FDA) and the European Medicines Agency (EM...

    Authors: Guntram Schernthaner, Heinz Drexel, Evgeny Moshkovich, Birute Zilaitiene, Emil Martinka, Leszek Czupryniak, Tamás Várkonyi, Andrej Janež, Kristine Ducena, Katarina Lalić, Tsvetalina Tankova, Martin Prázný, Lea Smirčić Duvnjak, Olga Sukhareva and Harald Sourij

    Citation: BMC Endocrine Disorders 2019 19:64

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  34. Content type: Case report

    Co-existing Cushing’s syndrome and primary aldosteronism caused by bilateral adrenocortical adenomas, secreting cortisol and aldosterone, respectively, have rarely been reported. Precise diagnosis and manageme...

    Authors: Kaiyun Ren, Jia Wei, Qilin Liu, Yuchun Zhu, Nianwei Wu, Ying Tang, Qianrui Li, Qianying Zhang, Yerong Yu, Zhenmei An, Jing Chen and Jianwei Li

    Citation: BMC Endocrine Disorders 2019 19:63

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  35. Content type: Research article

    Patients with type 2 diabetes mellitus (T2DM) have accelerated atherosclerosis as a pro thrombotic state that is associated with the platelet activation priming. Platelets, which undergo the continuous mild st...

    Authors: Razie Mahmoodian, Morteza Salimian, Mohsen Hamidpour, Ali Akbar Khadem-Maboudi and Ahmad Gharehbaghian

    Citation: BMC Endocrine Disorders 2019 19:62

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  36. Content type: Case report

    Insulin-derived amyloidosis is a skin-related complication of insulin therapy that interferes with insulin therapy. Although toxicities of in vitro-formed insulin amyloid fibrils have been well studied, the to...

    Authors: Keiichi Iwaya, Tamotsu Zako, Junta Fukunaga, Karin Margareta Sörgjerd, Kentaro Ogata, Koichiro Kogure, Hiroshi Kosano, Masayuki Noritake, Mizuo Maeda, Yukio Ando, Yoshiya Katsura and Terumasa Nagase

    Citation: BMC Endocrine Disorders 2019 19:61

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  37. Content type: Research article

    Survival from many cancer types is steadily increasing, and as a result, a growing number of cancer patients will live with other chronic diseases, of which diabetes is one of the most prevalent. This study ai...

    Authors: Anne Beiter Arreskov, Maria Å. Olsen, Sandra Sinius Pouplier, Volkert Siersma, Christen L. Andersen, Søren Friis and Niels de Fine Olivarius

    Citation: BMC Endocrine Disorders 2019 19:60

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  38. Content type: Research article

    The present study aimed to investigate the inhibitory effects of aminoguanidine (AG) and 2-bromoethylamine (2-BEA) on the semicarbazide-sensitive amine oxidase (SSAO) activity both in vitro and in vivo, and th...

    Authors: Chaosheng Li, Zhenhua Wang, Xiaoli Li and Jun Chen

    Citation: BMC Endocrine Disorders 2019 19:59

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  39. Content type: Research article

    In recent years, the relationship between thyroid stimulating hormone (TSH) and obesity has been widely discussed. However, it is unclear how thyroid hormone concentrations relate to body weight and its impact...

    Authors: Ranran Xu, Fei Huang, Shijie Zhang, Yongman Lv and Qingquan Liu

    Citation: BMC Endocrine Disorders 2019 19:58

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  40. Content type: Research article

    Although exercise seems to be beneficial for type 2 diabetes mellitus (T2DM) patients, there is limited research elucidating the optimal accessible indices of adiposity and insulin resistance for identifying e...

    Authors: Hong-Ting Zhu, Min Yu, Hao Hu, Qing-Fang He, Jin Pan and Ru-Ying Hu

    Citation: BMC Endocrine Disorders 2019 19:57

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  41. Content type: Research article

    Thyrotoxicosis is often caused by destructive thyroiditis (DT) or Graves’ disease (GD), and a prompt and accurate differential diagnosis for thyrotoxicosis is needed as management strategy differs. A meta-anal...

    Authors: Xiaojuan Peng, Shenglan Wu, Caiqun Bie, Huijun Tang, Zhe Xiong and Shaohui Tang

    Citation: BMC Endocrine Disorders 2019 19:56

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  42. Content type: Research article

    The diet quality of adults living in the United States has improved overtime. We aim to determine whether diet quality among adults with diabetes mellitus has changed over time, and to examine trends in socioe...

    Authors: Colin J. Orr, Thomas C. Keyserling, Alice S. Ammerman and Seth A. Berkowitz

    Citation: BMC Endocrine Disorders 2019 19:54

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  43. Content type: Research

    Parathyroid carcinoma is a rare neoplasm that may present sporadically or in the context of a genetic syndrome. Diagnosis and management are challenging due to the lack of clinical and pathological features th...

    Authors: Valentina Ferraro, Lucia Ilaria Sgaramella, Giovanna Di Meo, Francesco Paolo Prete, Francesco Logoluso, Francesco Minerva, Marica Noviello, Giuseppina Renzulli, Angela Gurrado and Mario Testini

    Citation: BMC Endocrine Disorders 2019 19(Suppl 1):46

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    This article is part of a Supplement: Volume 19 Supplement 1

  44. Content type: Research

    Medullary thyroid carcinoma is a neuroendocrine tumor belonging form a malignant growth of the thyroid parafollicular C-cells, representing from 1 to 10% of all thyroid cancer. The biochemical activity of medu...

    Authors: Claudio Gambardella, Chiara Offi, Renato Patrone, Guglielmo Clarizia, Claudio Mauriello, Ernesto Tartaglia, Francesco Di Capua, Sergio Di Martino, Roberto Maria Romano, Lorenzo Fiore, Alessandra Conzo, Giovanni Conzo and Giovanni Docimo

    Citation: BMC Endocrine Disorders 2019 19(Suppl 1):45

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    This article is part of a Supplement: Volume 19 Supplement 1

  45. Content type: Research

    The association between Hashimoto’s thyroiditis (HT) and papillary thyroid carcinoma (PTC) is a controversial question that is still under debate, its pathological significance and the eventual clinical implic...

    Authors: Giuseppa Graceffa, Renato Patrone, Salvatore Vieni, Silvia Campanella, Sergio Calamia, Iole Laise, Giovanni Conzo, Mario Latteri and Calogero Cipolla

    Citation: BMC Endocrine Disorders 2019 19(Suppl 1):26

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    This article is part of a Supplement: Volume 19 Supplement 1

  46. Content type: Case report

    Hypothyroidism, one of the prevalent endocrine disorders worldwide, has a broad spectrum of clinical manifestations, from an asymptomatic condition to myxedema coma. Although the majority of patients with hypo...

    Authors: Chung Gyo Seo, Kyoung Jin Kim, Euyhyun Park, Nam Hoon Kim, Joo Hyung Kim, Hee Young Kim, Sin Gon Kim and Kyeong Jin Kim

    Citation: BMC Endocrine Disorders 2019 19:52

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  47. Content type: Research article

    The molecular basis of the Turkish population with suspected maturity-onset diabetes of the young (MODY) has not been identified. This is the first study to investigate the association between HNF1A-gene single-n...

    Authors: Selvihan Beysel, Nilnur Eyerci, Ferda Alparslan Pinarli, Muhammed Kizilgul, Ozgur Ozcelik, Mustafa Caliskan and Erman Cakal

    Citation: BMC Endocrine Disorders 2019 19:51

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  48. Content type: Study protocol

    Teenagers and young adults with type 1 diabetes (T1D) experience significant burden managing this serious chronic condition and glycaemic control is at its unhealthiest during this life stage. Flash glucose mo...

    Authors: Sara E. Boucher, Andrew R. Gray, Martin de Bock, Esko J. Wiltshire, Barbara C. Galland, Paul A. Tomlinson, Jenny Rayns, Karen E. MacKenzie and Benjamin J. Wheeler

    Citation: BMC Endocrine Disorders 2019 19:50

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