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  1. Diabetic ketoacidosis (DKA) is an acute, major, life-threatening complication of diabetes that requires immediate treatment. Allergic reaction to insulin is rare, especially when using recombinant human insuli...

    Authors: Anh Dat Nguyen, Chinh Quoc Luong, Hieu Chi Chu, Van Khoa Dieu Nguyen, Chi Van Nguyen, Tuan Anh Nguyen, Quan Huu Nguyen, Ton Duy Mai, Dinh Van Nguyen, Bay Quang Nguyen, Thong Huu Tran, Phuong Viet Dao, Dat Tuan Nguyen, Nguyet Nhu Nguyen and Son Ngoc Do

    Citation: BMC Endocrine Disorders 2019 19:121

    Content type: Case report

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  2. Agenesis of the dorsal pancreas (ADP) is clinically rare, and it is usually accompanied by abdominal pain. Various disorders of glucose metabolism associating with ADP have been reported, but there are only tw...

    Authors: Tian Yang, Xudan Yang, Luping Wang and Jun Mo

    Citation: BMC Endocrine Disorders 2019 19:120

    Content type: Case report

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  3. The shape of the glucose response curve during an oral glucose tolerance test (OGTT) can predict β-cell function and insulin resistance. However, there have been few studies conducted on Chinese people. Thus, ...

    Authors: Xinqi Cheng, Na Yang, Yuxiu Li, Qi Sun, Ling Qiu, Lingling Xu, Fan Ping, Wei Li and Huabing Zhang

    Citation: BMC Endocrine Disorders 2019 19:119

    Content type: Research article

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  4. Diabetes is 7th largest cause of death worldwide, and prevalence is increasing rapidly in low-and middle-income countries. There is an urgent need to develop and test interventions to prevent and control diabe...

    Authors: Joanna Morrison, Kohenour Akter, Hannah Maria Jennings, Tasmin Nahar, Abdul Kuddus, Sanjit Kumer Shaha, Naveed Ahmed, Carina King, Hassan Haghparast-Bidgoli, Anthony Costello, A. K. Azad Khan, Kishwar Azad and Edward Fottrell

    Citation: BMC Endocrine Disorders 2019 19:118

    Content type: Research article

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  5. Exercise is known to induce multiple beneficial conditioning processes. Conversely, although exercise may generate several hormonal effects, an intrinsic hormonal conditioning process has not been reported. In...

    Authors: Flavio A. Cadegiani and Claudio E. Kater

    Citation: BMC Endocrine Disorders 2019 19:117

    Content type: Research article

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  6. We report a novel mutation within the StAR gene, causing congenital adrenal hyperplasia, with the so far unreported association with heterochromia iridis.

    Authors: Vera Splittstösser, Felix Schreiner, Bettina Gohlke, Maik Welzel, Paul-Martin Holterhus and Joachim Woelfle

    Citation: BMC Endocrine Disorders 2019 19:116

    Content type: Case report

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  7. The prevalence of obesity and its comorbidities, including type 2 diabetes mellitus (T2DM), is dramatically increasing throughout the world; however, the underlying aetiology is incompletely understood. Genome...

    Authors: Naomi L. Cook, Milos Pjanic, Andrew G. Emmerich, Abhiram S. Rao, Susanne Hetty, Joshua W. Knowles, Thomas Quertermous, Casimiro Castillejo-López and Erik Ingelsson

    Citation: BMC Endocrine Disorders 2019 19:115

    Content type: Research article

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  8. Pituitary metastasis is a rare condition with a poor prognosis. Very few patients with pituitary metastasis are symptomatic. It is often associated with presence of co-existing metastases to other organs. Isol...

    Authors: Sirinart Sirinvaravong, Peeradon Vibhatavata, Paweena Chunharojrith, Pornsuk Cheunsuchon and Sutin Sriussadaporn

    Citation: BMC Endocrine Disorders 2019 19:114

    Content type: Case report

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  9. Colorectal cancer (CRC) is the fourth most commonly diagnosed gastrointestinal (GI) malignancy and the third leading cause of cancer-related death worldwide. In the current case-control study, an association b...

    Authors: Ghodratollah Soltani, Arash Poursheikhani, Maryam Yassi, Abdorasool Hayatbakhsh, Matin Kerachian and Mohammad Amin Kerachian

    Citation: BMC Endocrine Disorders 2019 19:113

    Content type: Research article

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  10. Cytologically indeterminate thyroid nodules currently present a challenge for clinical decision-making. The main aim of our study was to determine whether the classifications, American College of Radiology (AC...

    Authors: Thayse Lozovoy Madsen Barbosa, Cleo Otaviano Mesa Junior, Hans Graf, Teresa Cavalvanti, Marcus Adriano Trippia, Ricardo Torres da Silveira Ugino, Gabriel Lucca de Oliveira, Victor Hugo Granella and Gisah Amaral de Carvalho

    Citation: BMC Endocrine Disorders 2019 19:112

    Content type: Research article

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  11. Barakat syndrome is an autosomal dominant rare genetic disease caused by haploinsufficiency of the GATA binding protein 3 (GATA3) gene. It is also known as HDR syndrome, and is characterized by varying degrees of...

    Authors: Anne D. D. Joseph, Nirmala D. Sirisena, Thirunavukarasu Kumanan, Vathualan Sujanitha, Veronika Strelow, Raina Yamamoto, Stefan Wieczorek and Vajira H. W. Dissanayake

    Citation: BMC Endocrine Disorders 2019 19:111

    Content type: Case report

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  12. Severe hypoglycaemia carries a significant risk of morbidity and mortality for people with type 1 diabetes. Economic costs are also high, estimated at approximately £13 million annually in England, UK. Continu...

    Authors: Parizad Avari, Rozana Ramli, Monika Reddy, Nick Oliver and Rachael Fothergill

    Citation: BMC Endocrine Disorders 2019 19:110

    Content type: Study protocol

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  13. Sarcopenia and sarcopenic obesity (SO) have a greater impact on the elderly. This study aimed to explore whether there were sex differences in the prevalence and adverse outcomes of sarcopenia and SO in commun...

    Authors: Yanping Du, Xiaodong Wang, Hua Xie, Songbai Zheng, Xiaoqing Wu, Xiaoying Zhu, Xuemei Zhang, Sihong Xue, Huilin Li, Wei Hong, Wenjing Tang, Minmin Chen, Qun Cheng and Jianqin Sun

    Citation: BMC Endocrine Disorders 2019 19:109

    Content type: Research article

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  14. The adipokine adipsin contributes to insulin resistance (IR), inflammation, and obesity, which are all regarded as high-risk factors for mild cognitive impairment (MCI) in patients with type 2 diabetes mellitu...

    Authors: Dan Guo, Yang Yuan, Rong Huang, Sai Tian, Jiaqi Wang, Hongyan Lin, Ke An, Jin Han and Shaohua Wang

    Citation: BMC Endocrine Disorders 2019 19:108

    Content type: Research article

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  15. Hypoglycemia is a common complication of insulin therapy in patients with Type 1 Diabetes Mellitus (DM). Awareness of hypoglycemic symptoms helps patients to recognize hypoglycemia and initiate self-treatment....

    Authors: Mohammad J. Alkhatatbeh, Nedaa A. Abdalqader and Mohammad A. Y. Alqudah

    Citation: BMC Endocrine Disorders 2019 19:107

    Content type: Research article

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  16. Lifestyle modification targeting weight management is the first-line treatment for women with Polycystic Ovary Syndrome (PCOS) regardless of presenting symptoms. Women with PCOS are more likely to gain more we...

    Authors: Siew Lim, Caroline A. Smith, Michael F. Costello, Freya MacMillan, Lisa Moran and Carolyn Ee

    Citation: BMC Endocrine Disorders 2019 19:106

    Content type: Research article

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  17. Clinical care of patients with cyclic Cushing’s syndrome (CS) is challenging. Classical pitfalls include incorrect subtyping, unnecessary surgical procedures and delayed definite treatment.

    Authors: Adriana Albani, Christina M. Berr, Felix Beuschlein, Marcus Treitl, Klaus Hallfeldt, Jürgen Honegger, Günter Schnauder and Martin Reincke

    Citation: BMC Endocrine Disorders 2019 19:105

    Content type: Case report

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  18. The relationship between breast cancer (BC) and thyroid disease (TD) is still controversial. The aim of the study was to investigate the possible coexistence of TD in patients with newly diagnosed BC and its c...

    Authors: Chiara Dobrinja, Serena Scomersi, Fabiola Giudici, Giulia Vallon, Alessio Lanzaro, Marina Troian, Deborah Bonazza, Andrea Romano, Fabrizio Zanconati, Nicolò de Manzini and Marina Bortul

    Citation: BMC Endocrine Disorders 2019 19:104

    Content type: Research

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  19. Medullary thyroid carcinoma is a malignant uncommon and aggressive tumour of the parafollicular C cells. In about 75% of cases it is sporadic while, in case of RET mutation, it is associated to multiple endocr...

    Authors: Claudio Gambardella, Chiara Offi, Guglielmo Clarizia, Roberto Maria Romano, Immacolata Cozzolino, Marco Montella, Rosa Maria Di Crescenzo, Massimo Mascolo, Angelo Cangiano, Sergio Di Martino, Giancarlo Candela and Giovanni Docimo

    Citation: BMC Endocrine Disorders 2019 19:103

    Content type: Case report

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  20. The relationship between thyroid nodules (TNs) and adiposity is controversial. This paper describes a cross-sectional investigation performed to determine the existence of any such relationship. To assess adip...

    Authors: Hui-xia Yang, Yu Zhong, Wei-hua Lv, Feng Zhang and Hong Yu

    Citation: BMC Endocrine Disorders 2019 19:102

    Content type: Research article

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  21. Diabetes Mellitus is an increasingly prevalent chronic disease characterized by the body’s inability to metabolize glucose. The objective of this study was to build an effective predictive model with high sens...

    Authors: Hang Lai, Huaxiong Huang, Karim Keshavjee, Aziz Guergachi and Xin Gao

    Citation: BMC Endocrine Disorders 2019 19:101

    Content type: Research article

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  22. Abnormal levels of liver enzymes, particularly aminotransferases, are prognostic features of non-alcoholic fatty liver disease (NAFLD). Considering the important role of dietary intakes in development of NAFLD...

    Authors: Parvin Mirmiran, Zahra Gaeini, Zahra Bahadoran and Fereidoun Azizi

    Citation: BMC Endocrine Disorders 2019 19:100

    Content type: Research article

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  23. Glucagon stimulation test (GST) is often employed to assess the insulin reserve of the pancreatic beta cells in diabetic subjects. The clinical significance of the increment of plasma glucose (Δglucose) by exo...

    Authors: Yasutaka Takeda, Yukihiro Fujita, Ryoichi Bessho, Mao Sato, Tomoe Abe, Tsuyoshi Yanagimachi, Hidemitsu Sakagami, Atsuko Abiko, Yumi Takiyama, Tsuguhito Ota and Masakazu Haneda

    Citation: BMC Endocrine Disorders 2019 19:99

    Content type: Research article

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  24. To investigate the prevalence of cardiovascular disease (CVD) risk factors and assess the 10-year risk of CVD in non-menopausal and postmenopausal women with type 2 diabetes mellitus (T2DM).

    Authors: Huanhuan Zhou, Chenghuan Zhang, Jingyu Ni and Xiaoyun Han

    Citation: BMC Endocrine Disorders 2019 19:98

    Content type: Research article

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  25. Charcot neuropathic osteoarthropathy (CNO) is one of the most devastating complications of neuropathy in patients with diabetes. Establishing diagnosis of CNO is difficult, due to the lack of clear clinical an...

    Authors: C. V. Loupa, E. Meimeti, A. Kokas, E. D. Voyatzoglou and A. Donou

    Citation: BMC Endocrine Disorders 2019 19:96

    Content type: Case report

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  26. Cholecystectomy, central obesity, and insulin resistance (IR) are established risk factors for nonalcoholic fatty liver disease (NAFLD). We aimed to examine the relative contributions and combined association ...

    Authors: Wenzhu Yue, Xingxing Sun and Tingting Du

    Citation: BMC Endocrine Disorders 2019 19:95

    Content type: Research article

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  27. Acromegaly is highly associated with thyroid disorders. However, the clinical characteristics of thyroid nodules in individuals with acromegaly who present with thyroid diseases have not been completely elucid...

    Authors: Dianshuang Xu, Bolin Wu, Xiaoju Li, Yunjiu Cheng, Dubo Chen, Yuefeng Fang, Qiu Du, Zhiyong Chen and Xiaodong Wang

    Citation: BMC Endocrine Disorders 2019 19:94

    Content type: Research article

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  28. Obese women with polycystic ovary syndrome (PCOS) may face additional barriers in achieving weight loss. We aimed to compare the effects of the hypocaloric low glycemic index (LGI) diet on anthropometric varia...

    Authors: Farnaz Shishehgar, Parvin Mirmiran, Maryam Rahmati, Maryam Tohidi and Fahimeh Ramezani Tehrani

    Citation: BMC Endocrine Disorders 2019 19:93

    Content type: Research article

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  29. Hypertriglyceridemia is often observed as the result of lipid abnormality and frequently associated with other lipid and metabolic disorders. Aggravation of hypertriglyceridemia is caused by various conditions...

    Authors: Shintaro Irie, Takatoshi Anno, Fumiko Kawasaki, Ryo Shigemoto, Shuhei Nakanishi, Kohei Kaku and Hideaki Kaneto

    Citation: BMC Endocrine Disorders 2019 19:92

    Content type: Case report

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  30. In 2015 approximately 5.0 million people were estimated to have died from diabetes. Poor glycemic control is the most determinant of diabetes-related complication and death. The percentage of patients whose bl...

    Authors: Yitagesu Mamo, Fekede Bekele, Tadesse Nigussie and Ameha Zewudie

    Citation: BMC Endocrine Disorders 2019 19:91

    Content type: Research article

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  31. Endothelial cell-specific molecule-1 (ESM-1) is a biomarker associated with tumor progression in pituitary adenoma. We specifically focused on one type of pituitary adenoma, namely null cell adenoma (NCA) and ...

    Authors: Shousen Wang, Zhifeng Wu, Liangfeng Wei and Jianhe Zhang

    Citation: BMC Endocrine Disorders 2019 19:90

    Content type: Research article

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  32. Diabetes-related kidney disease is associated with end-stage renal disease and mortality, but opportunities remain to quantify its association with cardiovascular and non-cardiovascular morbidity outcomes.

    Authors: James B. Wetmore, Suying Li, Thanh G. N. Ton, Yi Peng, Michael K. Hansen, Cheryl Neslusan, Ralph Riley, Jiannong Liu and David T. Gilbertson

    Citation: BMC Endocrine Disorders 2019 19:89

    Content type: Research article

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  33. Glycosylated hemoglobin (HbA1c) has a detrimental impact on the myocardium with left ventricular (LV) diastolic dysfunction. Obesity is a risk factor of type 2 diabetes. To understand the relationships between...

    Authors: Xin Zuo, Xueting Liu, Runtian Chen, Huiting Ou, Jiabao Lai, Youming Zhang and Dewen Yan

    Citation: BMC Endocrine Disorders 2019 19:88

    Content type: Research article

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  34. Subjects with prediabetes are at increased risk of future T2DM and cardiovascular disease (CVD) compared to NGT individuals. The OGTT (FPG = 100–125 and 2 h-PG = 140–199 mg/dl) and HbA1c 5.7–6.4% have been use...

    Authors: Saadallah Iskandar, Ayman Migahid, Dalia Kamal, Osama Megahed, Ralph A. DeFronzo, Mahmoud Zirie, Amin Jayyousi, Mahmood Al Jaidah and Muhammad Abdul-Ghani

    Citation: BMC Endocrine Disorders 2019 19:87

    Content type: Research article

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  35. The diagnosis of subacute thyroiditis (SAT) is based mainly on the presence of painful thyroid goitre and a significant increase in erythrocyte sedimentation rate (ESR). Proceeding according to these diagnosti...

    Authors: Magdalena Stasiak, Renata Michalak and Andrzej Lewinski

    Citation: BMC Endocrine Disorders 2019 19:86

    Content type: Case report

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  36. Older patients with type 2 diabetes mellitus represent a heterogeneous group in terms of metabolic profile. It makes glucose-lowering-therapy (GLT) complex to manage, as it needs to be individualised according...

    Authors: Antoine CHRISTIAENS, Michel P. HERMANS, Benoit BOLAND and Séverine HENRARD

    Citation: BMC Endocrine Disorders 2019 19:85

    Content type: Research article

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  37. In patients with diabetes mellitus, the urinary microalbumin-to-urine creatinine ratio (UACR) can not only predict the occurrence of diabetic nephropathy but also can be a risk factor for cardiovascular diseas...

    Authors: Juan Xie, Xiaoqing Wang, Yiyuan Zhang, Hailun Li, Yong Xu and Donghui Zheng

    Citation: BMC Endocrine Disorders 2019 19:84

    Content type: Research article

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  38. Thyroid dysfunction is one of the prevalent endocrine disorders. The relationship between lifestyle factors and thyroid dysfunction was not clear and some of the factors seemed paradoxical.

    Authors: Yanling Huang, Liangchun Cai, Yuanyuan Zheng, Jinxing Pan, Liantao Li, Liyao Zong, Wei Lin, Jixing Liang, Huibin Huang, Junping Wen and Gang Chen

    Citation: BMC Endocrine Disorders 2019 19:83

    Content type: Research article

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  39. Primary hyperparathyroidism (PHPT), which is mostly caused by a parathyroid adenoma, is fairly common in postmenopausal women but is relatively rare in pregnant women. PHPT-induced pancreatitis during pregnanc...

    Authors: Jun Yang, Meng-jie Dong and Feng Chen

    Citation: BMC Endocrine Disorders 2019 19:82

    Content type: Case report

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  40. Elderly patients with type 2 diabetes mellitus (T2DM) experience fractures more frequently than elderly individuals without diabetes. Fractures requiring hospitalization greatly affect quality of life, and alt...

    Authors: Takeshi Horii, Makiko Iwasawa, Yusuke Kabeya, Jyunichi Shimizu and Koichiro Atsuda

    Citation: BMC Endocrine Disorders 2019 19:81

    Content type: Research article

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  41. Myasthenia gravis (MG) is the most common disorder of neuromuscular transmission, and it is typified by fluctuating degrees and variable combinations of weakness in the ocular, bulbar, limb, and respiratory mu...

    Authors: Mi-Chu Lin, Ming-Hsien Tsai, Jyh-Gang Leu and Yu-Wei Fang

    Citation: BMC Endocrine Disorders 2019 19:80

    Content type: Case report

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  42. Traditionally Type 2 Diabetes Mellitus (T2DM) was associated with older age, but is now being increasingly diagnosed in younger populations due to the increasing prevalence of obesity and inactivity. We aimed ...

    Authors: Laura J. Gray, Emer M. Brady, Olatz Albaina, Charlotte L. Edwardson, Deirdre Harrington, Kamlesh Khunti, Joanne Miksza, João Filipe Raposo, Ellesha Smith, Andriani Vazeou, Itziar Vergara, Susann Weihrauch-Blüher and Melanie J. Davies

    Citation: BMC Endocrine Disorders 2019 19:79

    Content type: Research article

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  43. Hypoglycaemia, especially nocturnal, remains the main limiting factor of achieving good glycaemic control in type 1 diabetes.

    Authors: Rikke Mette Agesen, Amra Ciric Alibegovic, Henrik Ullits Andersen, Henning Beck-Nielsen, Peter Gustenhoff, Troels Krarup Hansen, Christoffer Hedetoft, Tonny Jensen, Claus Bogh Juhl, Susanne Søgaard Lerche, Kirsten Nørgaard, Hans-Henrik Parving, Lise Tarnow, Birger Thorsteinsson and Ulrik Pedersen-Bjergaard

    Citation: BMC Endocrine Disorders 2019 19:78

    Content type: Study protocol

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  44. Chronic inflammation has been associated with dysglycemia among people living with HIV (PLHIV). There is however, limited data regarding this phenomenon in sub-Sahara Africa (SSA). Therefore we assessed the le...

    Authors: Lilian Nkinda, Kirtika Patel, Benson Njuguna, Jean Pierre Ngangali, Peter Memiah, George M. Bwire, Mtebe V. Majigo, Mucho Mizinduko, Sonak D. Pastakia and Eligius Lyamuya

    Citation: BMC Endocrine Disorders 2019 19:77

    Content type: Research article

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  45. Sarcopenic obesity, central obesity combined with decreased skeletal muscle mass, is identified to be associated with metabolic syndrome and cardiovascular diseases; however, its role in the occurrence of non-...

    Authors: Xiaoyou Su, Jing Xu and Chao Zheng

    Citation: BMC Endocrine Disorders 2019 19:76

    Content type: Research article

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  46. To investigate any associations between blood glucose (BG) and lipid levels in patients with different glucose tolerance statuses, including type 2 diabetes (T2DM) and impaired glucose regulation (IGR) cases a...

    Authors: Shujin Wang, Guohong Li, Hong Zuo, Hua Yang, Lei Ma, Jia Feng, Yu Niu, Liming Ma, Songfang Liu, Ting Qi and Xufeng Liu

    Citation: BMC Endocrine Disorders 2019 19:75

    Content type: Research article

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  47. Type 2 Diabetes Mellitus (T2DM) has become an endemic disease. A number of interrelated factors increase the risk of the onset of T2DM, however much of the pathogenesis of the disease is associated with lifest...

    Authors: Linda Cloete, Brett G. Mitchell and Darren Morton

    Citation: BMC Endocrine Disorders 2019 19:74

    Content type: Study protocol

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  48. Several studies have indicated that inflammatory markers were associated with the risk of mild cognitive impairment (MCI) in type 2 diabetes (T2D). Serum folate was related to MCI as well as inflammation. Howe...

    Authors: Miaoyan Zheng, Baocheng Chang, Liqiang Tian, Chunyan Shan, Hui Chen, Yuxia Gao, Guowei Huang and Meilin Zhang

    Citation: BMC Endocrine Disorders 2019 19:73

    Content type: Research article

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  49. Further knowledge about the pubertal development mode of girls with Turner syndrome (TS) who have undergone hormone replacement therapy (HRT) is beneficial to the proposal of an optimal HRT regimen. This study...

    Authors: Song Guo, Jun Zhang, Yanhong Li, Huamei Ma, Qiuli Chen, Hongshan Chen and Minlian Du

    Citation: BMC Endocrine Disorders 2019 19:72

    Content type: Research article

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