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  1. Content type: Research article

    Fasting plasma glucose (FPG) is the most commonly used screening tool for diabetes in Sri Lanka. Cut-off values from American Diabetes Association recommendations are adopted in the absence of local data. We a...

    Authors: G. W. Katulanda, P. Katulanda, C. Dematapitiya, H. A. Dissanayake, S. Wijeratne, M. H. R. Sheriff and D. R. Matthews

    Citation: BMC Endocrine Disorders 2019 19:11

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  2. Content type: Research article

    Zinc-α2-glycoprotein (ZAG) is a recently novel lipolytic adipokine implicated in regulation of glucose and lipid metabolism in many metabolic disorders. In vitro and animal studies suggest that thyroid hormone...

    Authors: Xin-Hua Xiao, Xiao-Yan Qi, Jiao-Yang Li, Yi-Bing Wang, Ya-Di Wang, Zhe-Zhen Liao, Jing Yang, Li Ran, Ge-Bo Wen and Jiang-Hua Liu

    Citation: BMC Endocrine Disorders 2019 19:12

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  3. Content type: Case report

    Increased urinary free cortisol in response to the oral administration of dexamethasone is a paradoxical reaction mainly reported in patients with primary pigmented nodular adrenocortical disease. Here, we des...

    Authors: Chihiro Sakaguchi, Kenji Ashida, Kenichi Kohashi, Kenji Ohe, Yoichi Fujii, Seiichi Yano, Yayoi Matsuda, Shohei Sakamoto, Ryuichi Sakamoto, Yoshinao Oda, Masatoshi Nomura and Yoshihiro Ogawa

    Citation: BMC Endocrine Disorders 2019 19:13

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  4. Content type: Research article

    Vitamin-D2 (D2) treatment has been associated with a decrease in 25-hydroxy (25(OH)) vitamin-D3 (D3) level, suggesting that D3 treatment would be preferred to raise total 25(OH) vitamin-D (D) level. We postula...

    Authors: Muhammad M. Hammami, Kafa Abuhdeeb, Safa Hammami and Ahmed Yusuf

    Citation: BMC Endocrine Disorders 2019 19:8

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  5. Content type: Research article

    The most frequently used methods of assessing Graves’ orbithopathy (GO) include: Clinical Activity Score (CAS), ultrasonography (USG), computed tomography (CT), and magnetic resonance imaging (MRI). There exis...

    Authors: Piotr Szumowski, Saeid Abdelrazek, Łukasz Żukowski, Małgorzata Mojsak, Monika Sykała, Katarzyna Siewko, Katarzyna Maliszewska, Anna Popławska-Kita and Janusz Myśliwiec

    Citation: BMC Endocrine Disorders 2019 19:10

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  6. Content type: Research article

    The role of technology in the self-management of type 1 diabetes mellitus (T1DM) among children and young people is not well understood. Interventions should aim to improve key diabetes self-management behavio...

    Authors: Emily C. L. Knox, Helen Quirk, Cris Glazebrook, Tabitha Randell and Holly Blake

    Citation: BMC Endocrine Disorders 2019 19:7

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  7. Content type: Research article

    Metabolic syndrome (MetS) is a cluster of metabolic abnormalities that increases the cardiovascular risk. Regular physical exercise can promote benefits, but the MetS individuals are demotivated to perform it....

    Authors: Danúbia Sá-Caputo, Laisa Liane Paineiras-Domingos, Arlete Francisca-Santos, Elzi Martins dos Anjos, Aline Silva Reis, Mario Fritsch Toros Neves, Wille Oigman, Ricardo Oliveira, Andrea Brandão, Christiano Bittencourt Machado, Xavier Chiementin, Redha Taiar, Alessandro Sartório and Mario Bernardo-Filho

    Citation: BMC Endocrine Disorders 2019 19:6

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  8. Content type: Case report

    Insulin injection, especially with insulin analogs, occasionally induces the production of insulin antibodies with high binding capacity and low affinity, similar to the insulin autoantibodies characteristic o...

    Authors: Keizo Kaneko, Chihiro Satake, Tomohito Izumi, Mamiko Tanaka, Junpei Yamamoto, Yoichiro Asai, Shojiro Sawada, Junta Imai, Tetsuya Yamada and Hideki Katagiri

    Citation: BMC Endocrine Disorders 2019 19:5

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  9. Content type: Research article

    Several clinical trials have studied the effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs) on glycometabolism and cardiovascular risk factors since they were identified. Because of their cardiova...

    Authors: Xu Zhao, Kun Huang, Meijie Zheng and Junting Duan

    Citation: BMC Endocrine Disorders 2019 19:4

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  10. Content type: Research article

    Dipeptidyl peptidase-4 (DPP-4) inhibitors could effectively reduce HbA1C and postprandial hyperglycemia and could incur only minimal danger of hypoglycemia. Patients with uncontrolled diabetes might be treated by...

    Authors: Fu-Shun Yen, Jen-Huai Chiang, Chii-Min Hwu, Yu-Hsin Yen, Boniface J. Lin, James Cheng-Chung Wei and Chih-Cheng Hsu

    Citation: BMC Endocrine Disorders 2019 19:3

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  11. Content type: Research article

    Diabetic foot ulcers (DFU) are a common problem in longstanding diabetes. However, mortality outcomes in Australian patients with DFU are still unclear.

    Authors: Kanakamani Jeyaraman, Thomas Berhane, Mark Hamilton, Abhilash P. Chandra and Henrik Falhammar

    Citation: BMC Endocrine Disorders 2019 19:1

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  12. Content type: Research article

    Chronic diabetic complications may afflict all organ tissues, including those of the respiratory system. The six-minute walk test (6MWT) is an alternative and widely used method of assessing functional capacity a...

    Authors: Krzysztof Kuziemski, Wojciech Słomiński and Ewa Jassem

    Citation: BMC Endocrine Disorders 2019 19:2

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  13. Content type: Research article

    Sub-Saharan Africa continues to face the highest rate of mortality from diabetes in the world due to limited access to quality diabetes care. We assessed the quality of diabetes care in a rural diabetes clinic...

    Authors: Sonak D. Pastakia, Bernardo Nuche-Berenguer, Chelsea Regina Pekny, Benson Njuguna, Elizabeth Guinevere O’Hara, Stephanie Y. Cheng, Jeremiah Laktabai, Victor Buckwalter, Nicholas Kirui and Patrick Chege

    Citation: BMC Endocrine Disorders 2018 18:97

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  14. Content type: Research article

    Growth hormone (GH) is a heterogeneous protein composed of several molecular isoforms, the most abundant ones being the 22 kDa- and 20 kDa-GH. Exercise-induced secretion of GH isoforms has been extensively inv...

    Authors: A. E. Rigamonti, M. Haenelt, M. Bidlingmaier, A. De Col, S. Tamini, G. Tringali, R. De Micheli, L. Abbruzzese, C. R. Goncalves da Cruz, M. Bernardo-Filho, S. G. Cella and A. Sartorio

    Citation: BMC Endocrine Disorders 2018 18:96

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  15. Content type: Case report

    Insulinoma is a rare tumour representing 1–2% of all pancreatic neoplasms and it is malignant in only 10% of cases. Locoregional invasion or metastases define malignancy, whereas the dimension (> 2 cm), CK19 s...

    Authors: Mariasmeralda Caliri, Valentina Verdiani, Edoardo Mannucci, Vittorio Briganti, Luca Landoni, Alessandro Esposito, Giulia Burato, Carlo Maria Rotella, Massimo Mannelli and Alessandro Peri

    Citation: BMC Endocrine Disorders 2018 18:98

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  16. Content type: Research article

    Random glucose is widely measured in epidemiological studies and in the clinical setting when standardized fasting protocols and oral glucose tolerance testing or HbA1c measuring are not feasible. The relationshi...

    Authors: Jens Baumert, Christin Heidemann, Rebecca Paprott, Yong Du and Christa Scheidt-Nave

    Citation: BMC Endocrine Disorders 2018 18:95

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  17. Content type: Research article

    Malignant insulinoma is extremely rare and accounts for only 10% of total insulinoma cases. The goal of this study is to retrospectively analyze clinical data from 15 patients with malignant insulinoma treated...

    Authors: Jie Yu, Fan Ping, Huabing Zhang, Wei Li, Tao Yuan, Yong Fu, Kai Feng, Weibo Xia, Lingling Xu and Yuxiu Li

    Citation: BMC Endocrine Disorders 2018 18:92

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  18. Content type: Research article

    Hyponatraemia is the most common electrolyte disturbance amongst hospitalised patients. Both American and European guidelines recommend fluid restriction as first line treatment for SIADH, however differ on se...

    Authors: Kathryn Berkman, Kate Haigh, Ling Li, Jack Lockett, Goce Dimeski, Anthony Russell and Warrick J. Inder

    Citation: BMC Endocrine Disorders 2018 18:93

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  19. Content type: Research article

    Diabetes is a risk factor for cognitive impairment, but whether there is also a link between pre-diabetes and cognitive dysfunction is not yet fully established. The aim of this observational study was to inve...

    Authors: Elin Dybjer, Peter M. Nilsson, Gunnar Engström, Catherine Helmer and Katarina Nägga

    Citation: BMC Endocrine Disorders 2018 18:91

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  20. Content type: Research article

    Bariatric surgery is effective in remission of obesity comorbidities. This study was aimed at comparing CVD risk between morbidly obese patients with type 2 diabetes and pre-diabetes before and after bariatric...

    Authors: Matilde Rubio-Almanza, Rosa Cámara-Gómez, David Hervás-Marín, José Luis Ponce-Marco and Juan Francisco Merino-Torres

    Citation: BMC Endocrine Disorders 2018 18:90

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  21. Content type: Study protocol

    Alström syndrome (ALMS) is a very rare autosomal recessive monogenic disorder caused by a mutation in the ALMS1 gene and characterised by childhood onset obesity, dyslipidaemia, advanced non-alcoholic fatty liver...

    Authors: Shanat Baig, Vishy Veeranna, Shaun Bolton, Nicola Edwards, Jeremy W. Tomlinson, Konstantinos Manolopoulos, John Moran, Richard P. Steeds and Tarekegn Geberhiwot

    Citation: BMC Endocrine Disorders 2018 18:88

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  22. Content type: Research article

    Cognitive impairment is commonly observed in patients with Hashimoto thyroiditis (HT). Low levels of vitamin D have been correlated with cognitive impairment in non-HT population. We examined the association o...

    Authors: Jun Xu, Xiang-yun Zhu, Hui Sun, Xiao-qin Xu, Song-ao Xu, Yuan Suo, Li-jun Cao, Qiang Zhou, Hui-jie Yu and Wei-zhong Cao

    Citation: BMC Endocrine Disorders 2018 18:87

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  23. Content type: Case report

    Thyroid lymphomas are an exceptional finding in patients with thyroid nodules. Burkitt’s lymphoma is one of the rarest and most aggressive forms of thyroid lymphomas, and its prognosis depends on the earliness...

    Authors: Stella Bernardi, Andrea Michelli, Deborah Bonazza, Veronica Calabrò, Fabrizio Zanconati, Gabriele Pozzato and Bruno Fabris

    Citation: BMC Endocrine Disorders 2018 18:86

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  24. Content type: Research article

    After hormonal replacement therapy (HRT) including androgen replacement or sequential therapy of estrogen and progesterone, The combination of human chorionic gonadotropin (hCG) and human menopausal gonadotrop...

    Authors: Yinjie Gao, Bingqing Yu, Jiangfeng Mao, Xi Wang, Min Nie and Xueyan Wu

    Citation: BMC Endocrine Disorders 2018 18:85

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  25. Content type: Research article

    Soluble receptor for advanced glycation end-products (sRAGE) and advanced glycation end-products (AGE) have been associated with risks of cardiovascular disease. Because sRAGE is regarded as a scavenger to AGE...

    Authors: Kuang-Hsing Chiang, Jaw-Wen Chen, Shao-Sung Huang, Hsin-Bang Leu, Shing-Jong Lin and Po-Hsun Huang

    Citation: BMC Endocrine Disorders 2018 18:84

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  26. Content type: Case report

    Mucopolysaccharidosis type I (MPS I) results in significant disease burden and early treatment is important for optimal outcomes. Recognition of short stature and growth failure as symptoms of MPS I among pedi...

    Authors: Ana Maria Martins, Kristin Lindstrom, Sandra Obikawa Kyosen, Maria Veronica Munoz-Rojas, Nathan Thibault and Lynda E. Polgreen

    Citation: BMC Endocrine Disorders 2018 18:83

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  27. Content type: Case report

    Gitelman syndrome (GS) is an inherited autosomal recessive renal tubular disorder characterized by low levels of potassium and magnesium in the blood, decreased excretion of calcium in the urine, and elevated ...

    Authors: Haiyang Zhou, Xinhuan Liang, Yingfen Qing, Bihui Meng, Jia Zhou, Song Huang, Shurong Lu, Zhenxing Huang, Haiyan Yang, Yan Ma and Zuojie Luo

    Citation: BMC Endocrine Disorders 2018 18:82

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  28. Content type: Research article

    Proinsulin connecting peptide (C-Peptide) is a marker of the beta-cell function and has been considered a marker of insulin resistance whose evidence suggests were associated with cardiovascular mortality. Our...

    Authors: Romildo Luiz Monteiro Andrade, Denise P. Gigante, Isabel Oliveira de Oliveira and Bernardo Lessa Horta

    Citation: BMC Endocrine Disorders 2018 18:80

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  29. Content type: Research article

    Poor understanding of diabetes management targets is associated with worse disease outcomes. Patients may use different information than providers to assess their diabetes control. In this study, we identify t...

    Authors: Anjali Gopalan, Katherine Kellom, Kevin McDonough and Marilyn M. Schapira

    Citation: BMC Endocrine Disorders 2018 18:79

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  30. Content type: Case report

    Congenital lipoid adrenal hyperplasia (CLAH) is an extremely rare and the most severe form of congenital adrenal hyperplasia. Typical features include disorder of sex development, early-onset adrenal crisis an...

    Authors: Xiu Zhao, Zhe Su, Xia Liu, Jianming Song, Yungen Gan, Pengqiang Wen, Shoulin Li, Li Wang and Lili Pan

    Citation: BMC Endocrine Disorders 2018 18:78

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  31. Content type: Research article

    Type 2 diabetes mellitus has become one of the most important public health concerns worldwide. Due to its high prevalence and morbidity, there is an avid necessity to find new therapies that slow the progress...

    Authors: Miguel Ángel Gómez-Sámano, Jorge Enrique Baquerizo-Burgos, Melissa Fabiola Coronel Coronel, Buileng Daniela Wong-Campoverde, Fernando Villanueva-Martinez, Diego Molina-Botello, Jose Alonso Avila-Rojo, Lucía Palacios-Báez, Daniel Cuevas-Ramos, Francisco Javier Gomez-Perez, Alejandro Zentella-Dehesa, Álvaro Aguayo-González and Alfonso Gulias-Herrero

    Citation: BMC Endocrine Disorders 2018 18:77

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  32. Content type: Research article

    Hashimoto’s thyroiditis is a complex autoimmune thyroid disease, the onset of which is associated with environmental exposures and specific susceptibility genes. Its incidence in females is higher than its inc...

    Authors: Licheng Gong, Beihong Liu, Jing Wang, Hong Pan, Anhui Qi, Siyang Zhang, Jinyi Wu, Ping Yang and Binbin Wang

    Citation: BMC Endocrine Disorders 2018 18:76

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  33. Content type: Research article

    Improved glycemic control is the desired outcome after the discharge of patients with diabetes. We aimed to determine the efficacy of a basal-bolus insulin protocol in hospitalized patients with diabetes treat...

    Authors: Elena Chertok Shacham, Hila Kfir, Naama Schwartz and Avraham Ishay

    Citation: BMC Endocrine Disorders 2018 18:75

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  34. Content type: Study protocol

    Health care providers aim to stimulate self-management in type 2 diabetes (T2DM) patients. However, they have a limited number of patient contacts to do this. With the growing number of T2DM patients, innovati...

    Authors: Anne Meike Boels, Guy Rutten, Nicolaas Zuithoff, Ardine de Wit and Rimke Vos

    Citation: BMC Endocrine Disorders 2018 18:74

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  35. Content type: Study protocol

    Little evidence exists on the impact of diabetes risk scores, e.g. on physicians and patient’s behavior, perceived risk of persons, shared-decision making and particularly on patient’s health. The aim of this ...

    Authors: Esther Jacobs, Miguel Tamayo, Joachim Rosenbauer, Matthias B. Schulze, Oliver Kuss and Wolfgang Rathmann

    Citation: BMC Endocrine Disorders 2018 18:72

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  36. Content type: Research article

    When children with type 1 diabetes approach adolescence, they are encouraged to become more involved in diabetes self-management. This study explored the challenges pre-adolescent children encounter when self-...

    Authors: David Rankin, Jeni Harden, Katharine Barnard, Louise Bath, Kathryn Noyes, John Stephen and Julia Lawton

    Citation: BMC Endocrine Disorders 2018 18:71

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  37. Content type: Research article

    Vitamin D has been known since the twentieth Century for its benefits in bone health. Recent observational studies have demonstrated its benefits in infectious diseases such as tuberculosis and non-communicabl...

    Authors: Elizabeth Kagotho, Geoffrey Omuse, Nancy Okinda and Peter Ojwang

    Citation: BMC Endocrine Disorders 2018 18:70

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  38. Content type: Research article

    This study aimed to examine the switch from glargine+once daily insulin aspart (1 + 1 regimen) to glargine+insulin aspart 30 before breakfast combined with exercise and in patients with type 2 diabetes mellitu...

    Authors: Jing Li, Liming Wang, Fen Chen, Dongxia Xia and Lingling Miao

    Citation: BMC Endocrine Disorders 2018 18:69

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  39. Content type: Case report

    Congenital adrenal hyperplasia (CAH) resulting from steroid 11β-hydroxylase deficiency (11β-OHD) is caused by mutations in the CYP11B1 gene. It is the second major form of CAH associated with hypertension and hyp...

    Authors: Xianxian Yuan, Lin Lu, Shi Chen, Jun Jiang, Xiangqing Wang, Zhihui Liu, Huijuan Zhu, Hui Pan and Zhaolin Lu

    Citation: BMC Endocrine Disorders 2018 18:68

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  40. Content type: Study protocol

    Subclinical hypothyroidism is common in older people and its contribution to health and disease needs to be elucidated further. Observational and clinical trial data on the clinical effects of subclinical hypo...

    Authors: R. S. Du Puy, I. Postmus, D. J. Stott, M. R. Blum, R. K. E. Poortvliet, W. P. J. Den Elzen, R. P. Peeters, B. C. van Munster, B. H. R. Wolffenbuttel, R. G. J. Westendorp, P. M. Kearney, I. Ford, S. Kean, C. M. Messow, T. Watt, J. W. Jukema…

    Citation: BMC Endocrine Disorders 2018 18:67

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  41. Content type: Research article

    Insulin and insulin-like growth factor (IGF)-1 coupled with growth hormone helps control timing of sexual maturation. Mutations and variants in multiple genes are associated with development or reduced risk of...

    Authors: Hua-Pin Chang, Shun-Fa Yang, Shu-Li Wang and Pen-Hua Su

    Citation: BMC Endocrine Disorders 2018 18:66

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  42. Content type: Research article

    Metabolic syndrome (MetS) includes obesity, diabetes, dyslipidemia and hypertension. Its incidence is rapidly increasing worldwide, particularly in postmenopausal women. Estrogens regulate glucose homeostasis ...

    Authors: Lingxia Zhao, Xuemei Fan, Lin Zuo, Qiang Guo, Xiaole Su, Guangxia Xi, Ziyan Zhang, Jianlin Zhang and Guoping Zheng

    Citation: BMC Endocrine Disorders 2018 18:65

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  43. Content type: Research article

    To investigate the effect of a mildly elevated thyroid-stimulating hormone (TSH) concentration between 2.5 and 4.0 mIU/L during the first trimester on pregnancy outcomes in thyroid peroxydase antibody (TPOAb)-...

    Authors: Ping Li, Shuo Lin, Ling Li, Jinhui Cui, Shuisheng Zhou and Jianhui Fan

    Citation: BMC Endocrine Disorders 2018 18:64

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  44. Content type: Study protocol

    Type 2 diabetes is a serious clinical problem in both India and the UK. Adoption of a healthy lifestyle through dietary and physical activity modification can help prevent type 2 diabetes. However, implementin...

    Authors: Hazel Thomson, Nick Oliver, Ian F. Godsland, Ara Darzi, Weerachai Srivanichakorn, Azeem Majeed, Desmond G. Johnston, Arun Nanditha, Chamukuttan Snehalatha, Arun Raghavan, Priscilla Susairaj, Mary Simon, Krishnamoorthy Satheesh, Ambady Ramachandran, Stephen Sharp, Kate Westgate…

    Citation: BMC Endocrine Disorders 2018 18:63

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