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  1. Type 2 Diabetes mellitus (T2DM) is one of the most common endocrine diseases that weakens the immune system. Candida albicans, is part of the natural oral flora and increases in cases of compromised immune system...

    Authors: Atefe Halimi, Nazanin Mortazavi, Ali Memarian, Maryam Zahedi, Farhad Niknejad, Ahmad Sohrabi and Shakiba Javadian Sarraf
    Citation: BMC Endocrine Disorders 2022 22:296
  2. To explore facilitators and barriers to self-management engagement of Chinese people with poorly controlled type 2 diabetes.

    Authors: Yuan Liu, Jiajia Jiang, Wenjun You, Dandan Gong, Xiaoqing Ma, Min Wu and Feng Li
    Citation: BMC Endocrine Disorders 2022 22:294
  3. Tumor infiltration with cytotoxic CD8+ T-cells is associated with a favorable outcome in several neoplasms, including thyroid cancer. The chemokine axis CXCR4/SDF-1 correlates with more aggressive tumors, but ...

    Authors: Alexander Wilhelm, Isabelle Lemmenmeier, Alexandros Lalos, Alberto Posabella, Venkatesh Kancherla, Salvatore Piscuoglio, Tarik Delko, Markus von Flüe, Kathrin Glatz and Raoul André Droeser
    Citation: BMC Endocrine Disorders 2022 22:292
  4. Immune checkpoint inhibitors (ICI) targeting cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), programmed cell death protein 1 and its ligand (PD-1/PD-L1) have become the current standard-of-care for advan...

    Authors: Jeroen M. K. de Filette, Stéphanie André, Lynn De Mey, Sandrine Aspeslagh, Rafik Karmali, Bart J Van der Auwera and Bert Bravenboer
    Citation: BMC Endocrine Disorders 2022 22:291
  5. Type 2 diabetes (T2D) is a chronic, progressive lifestyle disease and the most rapidly growing health challenge of the twenty-first century. The American Diabetes Association recommends that T2D reversal can b...

    Authors: Chhavi Goyal Mehra, Annie Mattilda Raymond and Rekha Prabhu
    Citation: BMC Endocrine Disorders 2022 22:290
  6. Polycystic ovary syndrome (PCOS) is a common endocrine disorder with heterogeneous aetiology. It is characterized by irregular menses and or oligo/anovulation, hyper-androgenism, and polycystic ovaries. The pr...

    Authors: I. Ranathunga, T. G. Athukorala, M. R. Sumanatilleke and N. P. Somasundaram
    Citation: BMC Endocrine Disorders 2022 22:289
  7. The importance of genetic and dietary factors in occurrence and progression of chronic diseases such as metabolic syndrome (MetS) has been established. However, complex interrelationships, including direct and...

    Authors: Mahdieh Khodarahmi, Goli Siri, Farnoosh Erahimzadeh, Mahdieh Abbasalizad Farhangi and Dariush Shanehbandi
    Citation: BMC Endocrine Disorders 2022 22:288
  8. Ionizing radiation (IR) is high-energy radiation that has the potential to displace electrons from atoms and break chemical bonds. It has the ability to introduce mutations, DNA strand breakage, and cell death...

    Authors: Sanaa A. El-Benhawy, Enayat I. Fahmy, Sherien M. Mahdy, Galal H. Khedr, Alyaa S. Sarhan, Mohamed H. Nafady, Yousef A. Yousef Selim, Tarek M. Salem, Nehal Abu-Samra and Hany A. El Khadry
    Citation: BMC Endocrine Disorders 2022 22:287
  9. Previous studies have indicated an association between birth weight (BW) and type 2 diabetes mellitus (T2DM), but few studies have explored this relationship under different conditions of obesity in adulthood.

    Authors: Pu Song, Hui Hui, Manqing Yang, Peng Lai, Yan Ye, Ying Liu and Xuekui Liu
    Citation: BMC Endocrine Disorders 2022 22:285
  10. To investigate whether exposure to systemic antibiotics influences the risk of developing type 2 diabetes and overweight/obesity.

    Authors: Joel Nuotio, Teemu Niiranen, Tomi T. Laitinen, Jessica Miller, Matthew A. Sabin, Aki S. Havulinna, Jorma S. A. Viikari, Tapani Rönnemaa, Nina Hutri-Kähönen, Tomi P. Laitinen, Päivi Tossavainen, Veikko Salomaa, Olli T. Raitakari, David P. Burgner and Markus Juonala
    Citation: BMC Endocrine Disorders 2022 22:284
  11. People living with type 1 diabetes (PWT1D) are at increased risk for impairments in brain function, which may impact on daily life. Cognitive impairments in PWT1D might contribute to increasing eating disorder...

    Authors: Sylvain Iceta, Léonie Sohier, Catherine Bégin, Anne-Sophie Brazeau, Rémi Rabasa-Lhoret and Claudia Gagnon
    Citation: BMC Endocrine Disorders 2022 22:283
  12. To evaluate the association of vitamin D and thyroid-stimulating hormone (TSH) with weight loss (WL) percentage (%) in patients with diabetes/prediabetes and Class II/III obesity.

    Authors: Kemal Ağbaht and Serhan Vahit Pişkinpaşa
    Citation: BMC Endocrine Disorders 2022 22:282
  13. Irisin is a novel myokine both in mice and humans, and it can also be secreted by adipose tissue and the liver in a small amounts. There are few studies on irisin and bone metabolism. The aim of this study was...

    Authors: Junru Liu, Xing Wang, Dongmei Fan, Lina Sun, Weinan Zhang, Fuzai Yin and Bowei Liu
    Citation: BMC Endocrine Disorders 2022 22:281
  14. Coexistence of a catecholamine-secreting tumor and an adrenal cortical tumor is quite rare which makes both diagnosis and management challenging. The purpose of this article is to describe the presence of this...

    Authors: Yu-Chen Hsu, Cheng-Han Lee, Chen-Yu Chen and Chung-Jye Hung
    Citation: BMC Endocrine Disorders 2022 22:279
  15. 22q11.2 deletion syndrome (DiGeorge syndrome) is associated with multiple organ dysfunctions such as cardiac defects, immunodeficiency, and hypoplasia of parathyroid glands. Moreover, the phenotype of 22q11.2 ...

    Authors: Xuelian Chen, Lichuan Yang, Jianwei Li and Huiwen Tan
    Citation: BMC Endocrine Disorders 2022 22:278
  16. Type 2 diabetes mellitus (T2DM) and its related complications contribute to the high morbidity and mortality in worldwide. Skeletal muscle insulin resistance plays a critical role in the onset of T2DM due to t...

    Authors: Jianjuan Ke, Xiaohua Hu, Changhua Wang and Yemin Zhang
    Citation: BMC Endocrine Disorders 2022 22:276
  17. We aimed to explore descriptive epidemiology of T1 and T2 Diabetes Mellitus (DM) and to investigate demographic factors and comorbidities associated with all-cause mortality by aggregating and utilizing large-...

    Authors: Dinara Galiyeva, Arnur Gusmanov, Yesbolat Sakko, Alpamys Issanov, Kuralay Atageldiyeva, Kainar Kadyrzhanuly, Aiymzhan Nurpeissova, Marzhan Rakhimzhanova, Aigul Durmanova, Antonio Sarria-Santamera and Abduzhappar Gaipov
    Citation: BMC Endocrine Disorders 2022 22:275
  18. A novel non–insulin-based metabolic score for insulin resistance (METS‐IR) index has been proposed as a simple and reliable alternative insulin resistance (IR) marker, but its the predictive value in asymptoma...

    Authors: Zhenwei Wang, Xiaofang Hui, Xu Huang, Jingjie Li and Naifeng Liu
    Citation: BMC Endocrine Disorders 2022 22:274
  19. Depression is a risk factor for type 2 diabetes (T2D) and cardiovascular disease (CVD). The aims were to explore the prevalence of depression, anxiety, antidepressant use, obesity, Hemoglobin A1c > 64 mmol/mol...

    Authors: Eva O. Melin, Pär Wanby, Thomas Neumark, Sara Holmberg, Ann-Sofi Nilsson Neumark, Karin Johansson, Mona Landin-Olsson, Hans Thulesius, Magnus Hillman and Maria Thunander
    Citation: BMC Endocrine Disorders 2022 22:273
  20. We aimed to evaluate the performance of Chinese visceral adiposity index (CVAI), visceral adiposity index (VAI), lipid accumulation product (LAP), triglyceride glucose (TyG) as indices in screening abnormal gl...

    Authors: Qianqian Yin, Xiaonan Yan, Yijuan Cao and Jianhua Zheng
    Citation: BMC Endocrine Disorders 2022 22:272
  21. Gallbladder stone diseases (GSD) is a main risk factor of gallbladder cancer (GBC). This study aimed to reveal their bridge to metabolic syndrome.

    Authors: Yong Wan, Jianqin Zhang, Min Chen, Mao Ma and Binwu Sheng
    Citation: BMC Endocrine Disorders 2022 22:270
  22. Machine learning was a highly effective tool in model construction. We aim to establish a machine learning-based predictive model for predicting the cervical lymph node metastasis (LNM) in papillary thyroid mi...

    Authors: Yanling Huang, Yaqian Mao, Lizhen Xu, Junping Wen and Gang Chen
    Citation: BMC Endocrine Disorders 2022 22:269
  23. The role of the Endocannabinoids (ECs) in insulin resistance, and their association with visceral obesity and metabolic profile have been studied extensively. Since the association between ECs and metabolic fa...

    Authors: Hadi Bazyar, Khadijeh Nasiri, Parisa Ghanbari, Elahe Mohammadi, Neda Lotfi Yagin, Maryam Khazdouz, Vahideh Aghamohammadi and Shafagh Ali Asgarzadeh
    Citation: BMC Endocrine Disorders 2022 22:268
  24. Research suggests that fibrinogen (Fib) is related to mild cognitive impairment (MCI) and diabetic peripheral neuropathy (DPN) and the risk of MCI in patients with DPN is greatly increased, although no studies...

    Authors: Yong Zhuang, Huibin Huang, Zhenfei Fu, Jinying Zhang and Qingyan Cai
    Citation: BMC Endocrine Disorders 2022 22:267
  25. Diabetic peripheral neuropathy (DPN), due to its potential for causing morbidity and disability from foot ulcers and amputations, is increasingly becoming a source of concern in Saudi Arabia and worldwide. How...

    Authors: Lukman Femi Owolabi, Mushabab Alghamdi, Bappa Adamu, Magaji Garba Taura, Abubakar Jibo, Mohammed Almansour, Saeed Naseer Alaklabi, Mohammed Ali Alghamdi, Yousef Ayesh Alotaibi, Isa Adamu Imam, Reda Abdelrazak, Ahmad Rafaat and Muktar Hassan Aliyu
    Citation: BMC Endocrine Disorders 2022 22:266
  26. Ovarian steroid cell tumors (SCTs), not otherwise specified (NOS), are rare, with few large studies. The purpose of this study was to analyze the clinical features, prognosis, and treatment choices for these p...

    Authors: Mengyan Lin, Kechun Bao, Lingjia Lu, Shuhang Xu, Yun Liang, Xiaodong Cheng and Fenfen Wang
    Citation: BMC Endocrine Disorders 2022 22:265
  27. Proneurotensin (Pro-NT) is a strong predictor of cardiometabolic disease including type 2 diabetes and obesity, however, the effect of lifestyle change on Pro-NT has not been investigated in this context. Midd...

    Authors: Louise Bennet, Ayesha Fawad, Joachim Struck, Sara Lönn Larsson, Andreas Bergmann and Olle Melander
    Citation: BMC Endocrine Disorders 2022 22:264
  28. The purpose of this study was to survey the associations of six single nucleotide polymorphisms (SNPs) in the TMOD1 and PTCSC2 genes with thyroid carcinoma (TC).

    Authors: Kaijun Tong, Chang Zhang, Tingting Yang, Rongbiao Guo, Xinyuan Wang, Renyang Guan and Tianbo Jin
    Citation: BMC Endocrine Disorders 2022 22:263
  29. Non-islet cell tumour hypoglycemia (NICTH) is rarely encountered in clinical practice. Insulin-like growth factor 2 (IGF2) is the most common cause of NICTH observed in the setting of mesenchymal and epithelia...

    Authors: Mairead T. Crowley, Eibhlin Lonergan, Peter O’Callaghan, Caroline M. Joyce, M. Morita, Niamh Conlon and Domhnall J. O’Halloran
    Citation: BMC Endocrine Disorders 2022 22:262
  30. Lipid and glucose metabolism abnormalities are associated with nonalcoholic fatty liver disease (NAFLD). The triglyceride–glucose (TyG) index is a recently developed indicator that can identify individuals at ...

    Authors: Wei Li, Yan Wang, Feng He, Zhuo Liu, Jie Dong, Yuqi Zhang, Tianfang Li, Shengyun Liu and En Chen
    Citation: BMC Endocrine Disorders 2022 22:261
  31. Several studies on various bariatric surgeries involving patients with type 2 diabetes mellitus (T2DM) showed an overall rate of remission of hyperglycemia. However, there is little known about predictive fact...

    Authors: Marziyeh Moradi, Ali Kabir, Davood Khalili, Maziar Moradi Lakeh, Masoud Solaymani Dodaran, Abdolreza Pazouki, Mohammad Kermansaravi, Peyman Alibeigi, Hashem Moazenzadeh, Mohammad Reza Abdolhosseini, Foolad Eghbali and Hamid Reza Baradaran
    Citation: BMC Endocrine Disorders 2022 22:260
  32. Parathyroid carcinoma is an uncommon cause of PTH-dependent hypercalcemia. Only a handful of cases have been reported of parathyroid carcinoma during pregnancy.

    Authors: Chinthana Dematapitiya, Chiara Perera, Sivatharshiya Pathmanathan, Vindya Subasinghe, Gayani Anandagoda, Vajira Dissanayaka, Umesha Wijenayake, Preethi Dissanayake, Kavinga Gamage, Piyumi Wijewickrama and Manilka Sumanatilleke
    Citation: BMC Endocrine Disorders 2022 22:259
  33. In India, the prevalence of overweight among adolescents is on the rise, setting the stage for an increase in metabolic syndrome (MS). This paper presents the national prevalence of MS in adolescents in India.

    Authors: Sowmya Ramesh, Ransi Ann Abraham, Avina Sarna, Harshpal S. Sachdev, Akash Porwal, Nizamuddin Khan, Rajib Acharya, Praween K. Agrawal, Sana Ashraf and Lakshmi Ramakrishnan
    Citation: BMC Endocrine Disorders 2022 22:258
  34. Addison’s disease is primary adrenal dysfunction and is characterized by decrease of cortisol level and increase of adrenocorticotropic hormone (ACTH) level. It is known that infection is one of main causes of...

    Authors: Hideaki Kaneto, Fuminori Tatsumi, Mana Ohnishi, Yuichiro Iwamoto, Yukino Katakura, Masashi Shimoda, Shuhei Nakanishi, Kohei Kaku and Tomoatsu Mune
    Citation: BMC Endocrine Disorders 2022 22:257
  35. Growth differentiation factor 15 (GDF15) was newly discovered to be a promising target of metformin. The study was aimed to investigate the relationship between GDF15 and glycemic control after metformin treat...

    Authors: Fei Gao, Cheng Li, Yufei Wang, Jingyi Lu, Wei Lu, Jian Zhou, Jun Yin and Xiaojing Ma
    Citation: BMC Endocrine Disorders 2022 22:256
  36. The clinicopathological characteristics of solid pseudopapillary tumor (SPT) and pancreatic neuroendocrine neoplasm (pNEN) are different. We, therefore, systematically investigated the performance of the clini...

    Authors: Leshuang Wu, Tianle Zou, Dan Shi, Huan Cheng, Muhammad Shahbaz, Muhammad Umar, Tianfeng Li, Xianbin Zhang, Peng Gong and Yushan Wei
    Citation: BMC Endocrine Disorders 2022 22:255
  37. Gestational diabetes is one of the most common metabolic disorders during pregnancy. Some studies have reported the effect of vitamin D deficiency on the incidence of this disorder. Therefore, the purpose of t...

    Authors: Zahra Mirzaei-Azandaryani, Sakineh Mohammad-Alizadeh-Charandabi, Elnaz Shaseb, Shamsi Abbasalizadeh and Mojgan Mirghafourvand
    Citation: BMC Endocrine Disorders 2022 22:254
  38. The incidence of papillary thyroid cancer (PTC) concomitant with Hashimoto’s thyroiditis (HT) is gradually increasing over the past decades. This study aims to identify differentially expressed lncRNAs between...

    Authors: Yuepeng Zhang and Yueli Tian
    Citation: BMC Endocrine Disorders 2022 22:252
  39. Safety of sulfonylurea drugs in the treatment of Type 2 Diabetes is still under debate. The aim of this study was to compare the all-cause mortality and cardiovascular adverse events of sulfonylureas and drugs...

    Authors: Vallo Volke, Urmeli Katus, Annika Johannson, Karolin Toompere, Keiu Heinla, Kertu Rünkorg and Anneli Uusküla
    Citation: BMC Endocrine Disorders 2022 22:251
  40. NADPH oxidase 1 (Nox1), which is highly expressed in the colon, is thought to play a potential role in host defense as a physical and innate immune barrier against commensal or pathogenic microbes in the gastr...

    Authors: R. M. Simonyan, K. V. Simonyan, G. M. Simonyan, H. S. Khachatryan, M. A. Babayan, M. H. Danielyan, L. V. Darbinyan and M. A. Simonyan
    Citation: BMC Endocrine Disorders 2022 22:250
  41. Type 1 diabetes (T1DM) is an autoimmune disorder which can have short- and long-term adverse effects on health. Dietitians in diabetes offer specialist evidence-based advice to people with T1DM and provide edu...

    Authors: Sophie Rodebjer Cairns and Elisabeth Stoltz Sjöström
    Citation: BMC Endocrine Disorders 2022 22:249
  42. The prevalence of type 2 diabetes mellitus has increased in the past decades. We investigated the prevalence of diabetes and its awareness, treatment, and control among adult residents of Tehran.

    Authors: Alireza Oraii, Akbar Shafiee, Arash Jalali, Farshid Alaeddini, Soheil Saadat, Farzad Masoudkabir, Ali Vasheghani-Farahani, Amirhossein Heidari, Saeed Sadeghian, Mohamamdali Boroumand, Abbasali Karimi and Oscar H. Franco
    Citation: BMC Endocrine Disorders 2022 22:248
  43. Management of diabetes during fasting is a clinical challenge. Sodium glucose co-transporter -2 inhibitors (SGLT2i) are considered safe with a low risk of hypoglycemia. However, studies on SGLT2i are scarce. T...

    Authors: Ibrar Ahmed, Umar Yousaf Raja, Muhammad Umar Wahab, Tejhmal Rehman, Osama Ishtiaq, A. H. Aamir, Tahir Ghaffar, Abbas Raza, Suresh Kumar, Akhtar Sherin, Faisal Masood, Fawad Ahmad Randhawa, Ali Asghar and Sehrish Khan
    Citation: BMC Endocrine Disorders 2022 22:247
  44. This study aimed to evaluate the effect of Neuromuscular Electrical Stimulation (NMES) on serum glucose level in children and adolescents with type-1 diabetes.

    Authors: Fatemeh Fallah, Morteza Alijanpour, Soraya Khafri, Mohammad Pournasrollah and Ghadam Ali Talebi
    Citation: BMC Endocrine Disorders 2022 22:246

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