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  1. In patients with both Type 1 and Type 2 diabetes endogenous insulin secretion falls with time which changes treatment requirements, however direct measurement of endogenous insulin secretion is rarely performe...

    Authors: Angus G Jones, Rachel EJ Besser, Beverley M Shields, Timothy J McDonald, Suzy V Hope, Bridget A Knight and Andrew T Hattersley
    Citation: BMC Endocrine Disorders 2012 12:6
  2. Hypoglycemia is a common complication of diabetes treatment. This paper describes symptoms, predecessors, consequences and medications associated with the first episode of severe hypoglycemia among ACCORD part...

    Authors: Denise E Bonds, Michael E Miller, Jim Dudl, Mark Feinglos, Faramarz Ismail-Beigi, Saul Malozowski, Elizabeth Seaquist, Debra L Simmons and Ajay Sood
    Citation: BMC Endocrine Disorders 2012 12:5
  3. Pituitary disorders following pregnancy are an important yet under reported clinical entity in the developing world. Conversely, post partum panhypopituitarism has a more devastating impact on women in such se...

    Authors: Faheem G Sheriff, William P Howlett and Kajiru G Kilonzo
    Citation: BMC Endocrine Disorders 2012 12:4
  4. Animal studies suggest that local adipocyte-mediated activity of the renin-angiotensin-aldosterone system (RAAS) contributes to circulating levels, and may promote the development of obesity-related hypertensi...

    Authors: Conall M O'Seaghdha, Shih-Jen Hwang, Ramachandran S Vasan, Martin G Larson, Udo Hoffmann, Thomas J Wang and Caroline S Fox
    Citation: BMC Endocrine Disorders 2012 12:3
  5. Hypertriglyceridemia may be associated with important complications. The aim of this study is to estimate the magnitude of association and quality of supporting evidence linking hypertriglyceridemia to cardiov...

    Authors: M Hassan Murad, Ahmad Hazem, Fernando Coto-Yglesias, Svitlana Dzyubak, Shabnum Gupta, Irina Bancos, Melanie A Lane, Patricia J Erwin, Lars Berglund, Tarig Elraiyah and Victor M Montori
    Citation: BMC Endocrine Disorders 2012 12:2
  6. Sub-Saharan Africa is currently enduring the heaviest global burden of diabetes and diabetes care in such resource poor countries is far below standards. This study aims to describe the gaps in the care of Eth...

    Authors: Esayas K Gudina, Solomon T Amade, Fessahaye A Tesfamichael and Rana Ram
    Citation: BMC Endocrine Disorders 2011 11:19
  7. Recent evidence suggests that there may be a bidirectional, physiological link between hypogonadism and metabolic syndrome (MetS), and testosterone replacement therapy (TRT) has been shown to improve some symp...

    Authors: Rajib K Bhattacharya, Mohit Khera, Gary Blick, Harvey Kushner, Dat Nguyen and Martin M Miner
    Citation: BMC Endocrine Disorders 2011 11:18
  8. Older patients with newly diagnosed type 2 diabetes mellitus are less likely to receive antihyperglycaemic therapy compared to their younger counterparts. The purpose of this study was to assess the reasons of...

    Authors: Qiaoyi Zhang, Elizabeth Marrett, Kevin Jameson, Susanne Meiler, Michael J Davies, Larry Radican and Alan J Sinclair
    Citation: BMC Endocrine Disorders 2011 11:17
  9. We examined the association of biomarkers of inflammation and endothelial dysfunction with diabetes and metabolic syndrome (MetS) in persons from Inner Mongolia.

    Authors: Angela M Thompson, Yonghong Zhang, Weijun Tong, Tan Xu, Jing Chen, Li Zhao, Tanika N Kelly, Chung-Shiuan Chen, Lydia A Bazzano and Jiang He
    Citation: BMC Endocrine Disorders 2011 11:16
  10. Hyperthyroidism is accompanied by osteoporosis with higher incidence of fracture rates. The present work aimed to study bone status in hyperthyroidism and to elucidate the impact of severity, duration, and eti...

    Authors: El Hadidy M El Hadidy, Mohamed Ghonaim, Soma Sh Abd El Gawad and Mohamed Abou El Atta
    Citation: BMC Endocrine Disorders 2011 11:15
  11. Patients with acute myocardial infarction and newly detected abnormal glucose regulation have been shown to have a less favourable prognosis compared to patients with normal glucose regulation. The importance ...

    Authors: Eva C Knudsen, Ingebjørg Seljeflot, Michael Abdelnoor, Jan Eritsland, Arild Mangschau, Carl Müller, Harald Arnesen and Geir Ø Andersen
    Citation: BMC Endocrine Disorders 2011 11:14
  12. Latinos in the United States have a higher prevalence of type 2 diabetes than non-Latino whites, even after controlling for adiposity. Decreased adiponectin is associated with insulin resistance and predicts T...

    Authors: Rocio I Pereira, Cecilia CL Wang, Patrick Hosokawa, L Miriam Dickinson, Michel Chonchol, Mori J Krantz, John F Steiner, Daniel H Bessesen, Edward P Havranek and Carlin S Long
    Citation: BMC Endocrine Disorders 2011 11:13
  13. Development of type 2 diabetes mellitus (T2DM) is determined by the interactions of genetic and environmental factors. This study was designed to evaluate the possible role of VDR single nucleotide polymorphis...

    Authors: Sakineh Shab-Bidar, Tirang R Neyestani and Abolghassem Djazayery
    Citation: BMC Endocrine Disorders 2011 11:12
  14. Activation of peroxisome proliferator-activated receptor (PPAR)gamma is associated with bone loss and increased fracture risk, while PPARalpha activation seems to have positive skeletal effects. To further exp...

    Authors: Astrid K Stunes, Irene Westbroek, Björn I Gustafsson, Reidar Fossmark, Jan H Waarsing, Erik F Eriksen, Christiane Petzold, Janne E Reseland and Unni Syversen
    Citation: BMC Endocrine Disorders 2011 11:11
  15. Interferon-α in combination with ribavirin is the current gold standard for treatment of chronic hepatitis C. It is unknown if the development of autoimmune thyroid disease (TD) during treatment confers an imp...

    Authors: Huy A Tran, Tracey L Jones, Robert Gibson and Glenn EM Reeves
    Citation: BMC Endocrine Disorders 2011 11:10
  16. The once-weekly (QW) formulation of the glucagon-like peptide-1 receptor agonist exenatide has been demonstrated to improve A1C, fasting plasma glucose (FPG), body weight, serum lipid profiles, and blood press...

    Authors: Kristin Taylor, Kate Gurney, Jenny Han, Richard Pencek, Brandon Walsh and Michael Trautmann
    Citation: BMC Endocrine Disorders 2011 11:9
  17. There is limited literature on hypernatreamia in the setting of hyperglycaemic crisis. This is despite the fact that the presence of hypernatreamia may impact on the classification of hyperglycaemic crisis and...

    Authors: Chukwuma O Ekpebegh, Benjamin Longo-Mbenza, Augustin Nge-Okwe, Anthonia O Ogbera and Nomawethu T Tonjeni
    Citation: BMC Endocrine Disorders 2011 11:8
  18. Adipose tissue abundance relies partly on the factors that regulate adipogenesis, i.e. proliferation and differentiation of adipocytes. While components of the transcriptional program that initiates adipogenes...

    Authors: Pernille Keller, Valentina Gburcik, Natasa Petrovic, Iain J Gallagher, Jan Nedergaard, Barbara Cannon and James A Timmons
    Citation: BMC Endocrine Disorders 2011 11:7
  19. Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders caused by defects in the steroid 21 hydroxylase gene (CYP21A2). We studied the spectrum of mutations in CYP21A2 gene in a multi-...

    Authors: Aysha H Khan, Muniba Aban, Jamal Raza, Naeem ul Haq, Abdul Jabbar and Tariq Moatter
    Citation: BMC Endocrine Disorders 2011 11:5
  20. Accurately monitoring adherence to treatment with recombinant human growth hormone (r-hGH) enables appropriate intervention in cases of poor adherence. The electronic r-hGH auto-injector, easypod™, automatical...

    Authors: Mauro Bozzola, Michel Colle, Maria Halldin-Stenlid, Sylvain Larroque and Monia Zignani
    Citation: BMC Endocrine Disorders 2011 11:4
  21. The objective of this study was to characterize insulin use and examine factors associated with persistence to mealtime insulin among patients with type 2 diabetes (T2D) on stable basal insulin therapy initiat...

    Authors: Machaon M Bonafede, Anupama Kalsekar, Manjiri Pawaskar, Kimberly M Ruiz, Amelito M Torres, Karen R Kelly and Suellen M Curkendall
    Citation: BMC Endocrine Disorders 2011 11:3
  22. Haematopoietic stem cells undergo mobilization from bone marrow to blood in response to physiological stimuli such as ischemia and tissue injury. The aim of study was to determine the kinetics of circulating CD34

    Authors: Abel A Nathan, Viswanathan Mohan, Subash S Babu, Soumi Bairagi and Madhulika Dixit
    Citation: BMC Endocrine Disorders 2011 11:2
  23. Research has investigated whether communication technologies (e.g. mobile telephony, forums, email) can be used to transfer digital information between healthcare professionals and young people who live with d...

    Authors: Paul Sutcliffe, Steven Martin, Jackie Sturt, John Powell, Frances Griffiths, Ann Adams and Jeremy Dale
    Citation: BMC Endocrine Disorders 2011 11:1
  24. Insulin responses and insulin levels seem to decline with age. However, the question of beta cell impairment attributable to ageing has been sparsely addressed in population-based studies. Non-fasting insulin ...

    Authors: Bente Bryhni, Egil Arnesen and Trond G Jenssen
    Citation: BMC Endocrine Disorders 2010 10:21
  25. Glucagon-like peptide (GLP-1) analogues are a new class of drugs used in the treatment of type 2 diabetes. They are given by injection, and regulate glucose levels by stimulating glucose-dependent insulin secr...

    Authors: Deepson S Shyangdan, Pamela L Royle, Christine Clar, Pawana Sharma and Norman R Waugh
    Citation: BMC Endocrine Disorders 2010 10:20
  26. The most common cause of hypopituitarism is pituitary adenoma. However, in the case of suprasellar masses different etiologies are possible. We report an unusual case of primary suprasellar lymphoma presented ...

    Authors: Zouhour Fadoukhair, Mounia Amzerin, Nabil Ismaili, Rhizlane Belbaraka, Rachida Latib, Yassir Sbitti, Hind M'rabti, Saber Boutayeb, Mohammed Ichou and Hassan Errihani
    Citation: BMC Endocrine Disorders 2010 10:19
  27. To investigate disease progression the first 12 months after diagnosis in children with type 1 diabetes negative (AAB negative) for pancreatic autoantibodies [islet cell autoantibodies(ICA), glutamic acid deca...

    Authors: Sven Pörksen, Lene Bjerke Laborie, Lotte Nielsen, Marie Louise Max Andersen, Tone Sandal, Heidi de Wet, Erik Schwarcz, Jan Åman, Peter Swift, Mirjana Kocova, Eugen J Schönle, Carine de Beaufort, Philip Hougaard, Frances Ashcroft, Anders Molven, Mikael Knip…
    Citation: BMC Endocrine Disorders 2010 10:16
  28. Diabetes mellitus places a considerable burden on patients in terms of morbidity and mortality and on society in terms of costs. Costs related to diabetes are expected to increase due to increasing prevalence ...

    Authors: Oddvar Solli, Trond Jenssen and Ivar S Kristiansen
    Citation: BMC Endocrine Disorders 2010 10:15
  29. At diabetes diagnosis major decisions about life-style changes and treatments are made based on characteristics measured shortly after diagnosis. The predictive value for mortality of these early characteristi...

    Authors: Niels de Fine Olivarius, Volkert Siersma, Anni BS Nielsen, Lars J Hansen, Lotte Rosenvinge and Carl Erik Mogensen
    Citation: BMC Endocrine Disorders 2010 10:14
  30. Cause-specific mortality is a commonly used endpoint of clinical trials or prospective studies. However, it is sometimes difficult for physician to determine the underlying-cause-of-death (UCD), especially for...

    Authors: Tsung-Hsueh Lu, Ching-Fai Kwok and Low-Tone Ho
    Citation: BMC Endocrine Disorders 2010 10:13
  31. Hypovitaminosis D is a common condition among elderly individuals in temperate-climate countries, with a clear seasonal variation on 25 hydroxyvitamin D levels, increasing after summer and decreasing after win...

    Authors: Sergio S Maeda, Ilda S Kunii, Lilian F Hayashi and Marise Lazaretti-Castro
    Citation: BMC Endocrine Disorders 2010 10:12
  32. The metabolic syndrome (MetS) concept is widely used in public health and clinical settings without an agreed pathophysiology. We have re-examined the MetS in terms of body fuels, so as to provide a coherent c...

    Authors: Mark L Wahlqvist, Hsing-Yi Chang, Chu-Chih Chen, Chih-Cheng Hsu, Wan-Chi Chang, Wuan-Szu Wang and Chao A Hsiung
    Citation: BMC Endocrine Disorders 2010 10:11
  33. Pituitary adenomas are associated with a variety of clinical manifestations resulting from excessive hormone secretion and tumor mass effects, and require a multidisciplinary management approach. This article ...

    Authors: Beverly MK Biller, Annamaria Colao, Stephan Petersenn, Vivien S Bonert and Marco Boscaro
    Citation: BMC Endocrine Disorders 2010 10:10
  34. Transcription factor 7-like 2 (TCF7L2) has emerged as a consistently replicated susceptibility gene for type 2 diabetes, however, whether the TCF7L2 gene also has similar effects on the retinal microvasculature i...

    Authors: Yu Yan, Ronald Klein, Gerardo Heiss, Cynthia J Girman, Ethan M Lange, Barbara E Klein, Kathryn M Rose, Eric Boerwinkle, James S Pankow, Frederick L Brancati, Christie M Ballantyne, Anna Köttgen and Kari E North
    Citation: BMC Endocrine Disorders 2010 10:9
  35. In recent years, there has been an increasing attention to thyroid function in paediatric obese patients. In the present study we aimed 1) to determine the prevalence of abnormally elevated thyroid-stimulating...

    Authors: Anna Grandone, Nicola Santoro, Filomena Coppola, Paolo Calabrò, Laura Perrone and Emanuele Miraglia del Giudice
    Citation: BMC Endocrine Disorders 2010 10:8
  36. In a previous pooled analysis of 12 double-blind clinical studies that included data on 6,139 patients with type 2 diabetes, treatment with sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, was shown to...

    Authors: Debora Williams-Herman, Samuel S Engel, Elizabeth Round, Jeremy Johnson, Gregory T Golm, Hua Guo, Bret J Musser, Michael J Davies, Keith D Kaufman and Barry J Goldstein
    Citation: BMC Endocrine Disorders 2010 10:7
  37. Low skeletal muscle mass is associated with insulin resistance and metabolic syndrome. Serum creatinine may serve as a surrogate marker of muscle mass, and a possible relationship between low serum creatinine ...

    Authors: Jøran Hjelmesæth, Jo Røislien, Njord Nordstrand, Dag Hofsø, Helle Hager and Anders Hartmann
    Citation: BMC Endocrine Disorders 2010 10:6
  38. Endothelial progenitor cells (EPCs) play an important role in vascular repair and a decrease in the number of EPCs is observed in type 2 diabetes. However, there is no report on the change of EPCs after glycem...

    Authors: Worachat Churdchomjan, Pakpoom Kheolamai, Sirikul Manochantr, Pirath Tapanadechopone, Chairat Tantrawatpan, Yaowalak U-pratya and Surapol Issaragrisil
    Citation: BMC Endocrine Disorders 2010 10:5
  39. Type 2 diabetes mellitus (T2DM) and several types of neurodegeneration, including Alzheimer's, are linked to insulin-resistance, and chronic high dietary fat intake causes T2DM with mild neurodegeneration. Int...

    Authors: Ming Tong, Lisa Longato and Suzanne M de la Monte
    Citation: BMC Endocrine Disorders 2010 10:4
  40. Obesity, type 2 diabetes mellitus (T2D) and unhealthy blood lipid profile are strongly associated with the risk of developing cardiovascular disease (CVD). We examined whether blood lipid changes with short te...

    Authors: Peter Weeke, Charlotte Andersson, Emil L Fosbøl, Bente Brendorp, Lars Køber, Arya M Sharma, Nick Finer, Philip T James, Ian D Caterson, Richard A Rode and Christian Torp-Pedersen
    Citation: BMC Endocrine Disorders 2010 10:3
  41. Iodine deficiency is a global problem representing the most common preventable cause of mental retardation. Recently, the impact of subtle deficiencies in iodine intake on children and pregnant women has been ...

    Authors: Marcus M Cranston, Margaret AK Ryan, Tyler C Smith, Carter J Sevick and Stephanie K Brodine
    Citation: BMC Endocrine Disorders 2010 10:2
  42. Mice lacking Receptor-interacting protein 140 (RIP140) have reduced body fat which at least partly is mediated through increased lipid and glucose metabolism in adipose tissue. In humans, RIP140 is lower expresse...

    Authors: Niklas Mejhert, Jurga Laurencikiene, Amanda T Pettersson, Maria Kaaman, Britta M Stenson, Mikael Rydén and Ingrid Dahlman
    Citation: BMC Endocrine Disorders 2010 10:1
  43. A significant body of literature indicates that melatonin, a hormone primarily produced nocturnally by the pineal gland, is an important scavenger of hydroxyl radicals and other reactive oxygen species. Melato...

    Authors: Zoreh Davanipour, Henrik E Poulsen, Allan Weimann and Eugene Sobel
    Citation: BMC Endocrine Disorders 2009 9:22
  44. Numerous studies have reported that age-induced increased parathyroid hormone plasma levels are associated with cognitive decline and dementia. Little is known about the correlation that may exist between neur...

    Authors: Eric R Braverman, Thomas JH Chen, Amanda LC Chen, Vanessa Arcuri, Mallory M Kerner, Anish Bajaj, Javier Carbajal, Dasha Braverman, B William Downs and Kenneth Blum
    Citation: BMC Endocrine Disorders 2009 9:21
  45. Acromegaly, an orphan disease usually caused by a benign pituitary tumour, is characterised by hyper-secretion of growth hormone (GH) and insulin-like growth factor I (IGF-1). It is associated with reduced lif...

    Authors: David J Moore, Yaser Adi, Martin J Connock and Sue Bayliss
    Citation: BMC Endocrine Disorders 2009 9:20

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