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  1. The corticotropin-releasing hormone (CRH) challenge test can distinguish the disorders of the hypothalamus from those of the pituitary. However, the pathophysiology of hypothalamic disorder (HD) has not been f...

    Authors: Yuji Hataya, Marie Okubo, Takuro Hakata, Kanta Fujimoto, Toshio Iwakura and Naoki Matsuoka
    Citation: BMC Endocrine Disorders 2022 22:312
    Content type: Research Published on:

  2. Diabetic retinopathy is a complication of diabetes affecting the eyes and can lead to blindless if left untreated. Several significant risk factors have been reported for DR, of which several can be classified...

    Authors: Mike Trott, Robin Driscoll and Shahina Pardhan
    Citation: BMC Endocrine Disorders 2022 22:311
    Content type: Research article Published on:

  3. Insulinoma is an uncommon insulin-secreting neuroendocrine tumor that presents with severe recurrent hypoglycemia. Although cases of extrapancreatic insulinomas have been reported, the majority of insulinomas ...

    Authors: Michelle P. Walker, Vikram Shenoy, David C. Metz, Charles A. Stanley, Douglas Fraker, Vinay Chandrasekhara and Anastassia Amaro
    Citation: BMC Endocrine Disorders 2022 22:310
    Content type: Case report Published on:

  4. Osteoporosis is a very common bone disease in the elderly population and can lead to fractures and disability. Malnutrition can lead to osteoporosis. The geriatric nutritional risk index (GNRI) is a tool used ...

    Authors: Yuanyuan JI, Nan Geng, Yingchun Niu, Hang Zhao, Wenjie Fei, Shuchun Chen and Lu ping Ren
    Citation: BMC Endocrine Disorders 2022 22:308
    Content type: Research article Published on:

  5. Diabetic kidney disease (DKD) is highly prevalent among patients with diabetes mellitus. It affects approximately 20% of diabetic patients, who are believed to be more than 400 million individuals. The objecti...

    Authors: Hassan Ali Abdelwahid, Hesham Mohamed Dahlan, Gassem Maoudhah Mojemamy and Gasem Hussein Darraj
    Citation: BMC Endocrine Disorders 2022 22:307
    Content type: Research article Published on:

  6. Adropin is a potent metabolic regulator of insulin sensitivity and glycolipid metabolism. The present study investigated the effects of sitagliptin on adropin and metabolic parameters in participants with newl...

    Authors: Qiu Wang, Yu An, Lin Zhang, Yuanying Zhang, Guang Wang and Jia Liu
    Citation: BMC Endocrine Disorders 2022 22:306
    Content type: Research Published on:

  8. Meteorin-like (Metrnl) is a newly discovered adipomyokine that regulates systemic energy homeostasis. Both thyroid hormones and Metrnl increase energy expenditure and induce browning of adipose tissue. Thus, t...

    Authors: Xiaohui Wen, Xiaoyu Ding, Xiaona Chang, Jiaxuan Wang, Qiu Wang, Jia Liu and Guang Wang
    Citation: BMC Endocrine Disorders 2022 22:304
    Content type: Research Published on:

  9. Low Magnesium (Mg) dietary intake has been associated with increased risk of type 2 diabetes mellitus (T2DM). Furthermore, in patients with T2DM, hypomagnesemia is associated with worst glycaemic control. Bariatr...

    Authors: Silva MM, Neves JS, Borges-Canha M, Mendes AP, Fonseca MJ, Mendonça F, Ferreira MJ, Salazar D, Pedro J, Guerreiro V, Lau E, Varela A, Freitas P and Carvalho D
    Citation: BMC Endocrine Disorders 2022 22:303
    Content type: Research Published on:

  10. Data is inconsistent and, for the most part, not sufficient to demonstrate the association between serum Prolactin (PRL) concentration within the physiologic range and the incidence rate of type 2 Diabetes Mel...

    Authors: Atrin Niknam, Fatemeh Mahboobifard, Maryam Rahmati, Faezeh Firouzi, Ehsan Rojhani, Fereidoun Azizi and Fahimeh Ramezani Tehrani
    Citation: BMC Endocrine Disorders 2022 22:302
    Content type: Research Published on:

  11. Diabetic ketoacidosis (DKA) is one of the most severe acute complications of type 1 diabetes mellitus (T1DM). Patients with DKA of different severities may have different clinical manifestations, serum biochem...

    Authors: Qingxu Liu, Xiaoqin Yin and Pin Li
    Citation: BMC Endocrine Disorders 2022 22:301
    Content type: Research Published on:

  12. 17α-hydroxylase deficiency (17OHD) is a rare autosomal recessive disorder. Aldosterone levels are usually low in patients with 17OHD. However, among the approximately 150 cases of 17OHD reported to date, aldos...

    Authors: Yuki Ishinoda, Asuka Uto, Yoshifumi Yamada, Maki Okazaki, Hidetomo Asada, Seina Wakamatsu, Isao Kurihara, Hironori Shibata, Tomohiro Ishii, Tomonobu Hasegawa, Hiroo Kumagai and Akira Kasuga
    Citation: BMC Endocrine Disorders 2022 22:300
    Content type: Case report Published on:

  13. GnRHa treatment was established for improving final adult height (FAH) in children presenting with Idiopathic central precocious puberty (ICPP) up to age 8, while several controversies remained for older age g...

    Authors: Ming-ming Ni, Shu-ting Yang, Wen-wen Wu, Shan-shan Wang, Man Li, Qing-qing Liu and Xing Ji
    Citation: BMC Endocrine Disorders 2022 22:299
    Content type: Research Published on:

  14. Polycystic ovary syndrome (PCOS) is diagnosed based on chronic anovulation, androgen excess (clinical and/or biochemical), and polycystic ovaries in ultrasound. The aim of the present study was to evaluate whi...

    Authors: Asieh Mansour, Amir Pejman Hashemi Taheri, Behnaz Moradi, Mohammad Reza Mohajeri-Tehrani, Mostafa Qorbani, Sahar Ghorbani Pashakolaee, Milad Sanginabadi and Sayed Mahmoud Sajjadi-Jazi
    Citation: BMC Endocrine Disorders 2022 22:298
    Content type: Research Published on:

  15. Diabetes Mellitus (DM) is a fast-growing health problem that imposes an enormous economic burden. Several studies demonstrated the association between physical inactivity and predicting the incidence of diabet...

    Authors: Abdelrahman A. Jamiel, Husam I. Ardah, Amjad M. Ahmed and Mouaz H. Al-Mallah
    Citation: BMC Endocrine Disorders 2022 22:297
    Content type: Research Published on:

  16. Type 2 Diabetes mellitus (T2DM) is one of the most common endocrine diseases that weakens the immune system. Candida albicans, is part of the natural oral flora and increases in cases of compromised immune system...

    Authors: Atefe Halimi, Nazanin Mortazavi, Ali Memarian, Maryam Zahedi, Farhad Niknejad, Ahmad Sohrabi and Shakiba Javadian Sarraf
    Citation: BMC Endocrine Disorders 2022 22:296
    Content type: Research Published on:

  17. Sodium-Glucose-Co-Transporter 2 (SGLT2) inhibitor (Empagliflozin) is an effective drug in controlling blood glucose through predominantly glycosuria. Glycosuria increases the risk of genitourinary infections i...

    Authors: Azizul Hasan Aamir, Umar Yousaf Raja, Faisal Masood Qureshi, Ali Asghar, Saeed Ahmed Mahar, Ibrar Ahmed, Tahir Ghaffar, Jamal Zafar, Mohammad Imtiaz Hasan, Amna Riaz, Syed Abbas Raza, Irshad Ahmed Khosa, Jahanzeb Khan and Jaffer Bin Baqar
    Citation: BMC Endocrine Disorders 2022 22:295
    Content type: Research Published on:

  18. To explore facilitators and barriers to self-management engagement of Chinese people with poorly controlled type 2 diabetes.

    Authors: Yuan Liu, Jiajia Jiang, Wenjun You, Dandan Gong, Xiaoqing Ma, Min Wu and Feng Li
    Citation: BMC Endocrine Disorders 2022 22:294
    Content type: Research article Published on:

  20. Tumor infiltration with cytotoxic CD8+ T-cells is associated with a favorable outcome in several neoplasms, including thyroid cancer. The chemokine axis CXCR4/SDF-1 correlates with more aggressive tumors, but ...

    Authors: Alexander Wilhelm, Isabelle Lemmenmeier, Alexandros Lalos, Alberto Posabella, Venkatesh Kancherla, Salvatore Piscuoglio, Tarik Delko, Markus von Flüe, Kathrin Glatz and Raoul André Droeser
    Citation: BMC Endocrine Disorders 2022 22:292
    Content type: Research Published on:

  21. Immune checkpoint inhibitors (ICI) targeting cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), programmed cell death protein 1 and its ligand (PD-1/PD-L1) have become the current standard-of-care for advan...

    Authors: Jeroen M. K. de Filette, Stéphanie André, Lynn De Mey, Sandrine Aspeslagh, Rafik Karmali, Bart J Van der Auwera and Bert Bravenboer
    Citation: BMC Endocrine Disorders 2022 22:291
    Content type: Case report Published on:

  22. Type 2 diabetes (T2D) is a chronic, progressive lifestyle disease and the most rapidly growing health challenge of the twenty-first century. The American Diabetes Association recommends that T2D reversal can b...

    Authors: Chhavi Goyal Mehra, Annie Mattilda Raymond and Rekha Prabhu
    Citation: BMC Endocrine Disorders 2022 22:290
    Content type: Research Published on:

  23. Polycystic ovary syndrome (PCOS) is a common endocrine disorder with heterogeneous aetiology. It is characterized by irregular menses and or oligo/anovulation, hyper-androgenism, and polycystic ovaries. The pr...

    Authors: I. Ranathunga, T. G. Athukorala, M. R. Sumanatilleke and N. P. Somasundaram
    Citation: BMC Endocrine Disorders 2022 22:289
    Content type: Research Published on:

  24. The importance of genetic and dietary factors in occurrence and progression of chronic diseases such as metabolic syndrome (MetS) has been established. However, complex interrelationships, including direct and...

    Authors: Mahdieh Khodarahmi, Goli Siri, Farnoosh Erahimzadeh, Mahdieh Abbasalizad Farhangi and Dariush Shanehbandi
    Citation: BMC Endocrine Disorders 2022 22:288
    Content type: Research Published on:

  25. Ionizing radiation (IR) is high-energy radiation that has the potential to displace electrons from atoms and break chemical bonds. It has the ability to introduce mutations, DNA strand breakage, and cell death...

    Authors: Sanaa A. El-Benhawy, Enayat I. Fahmy, Sherien M. Mahdy, Galal H. Khedr, Alyaa S. Sarhan, Mohamed H. Nafady, Yousef A. Yousef Selim, Tarek M. Salem, Nehal Abu-Samra and Hany A. El Khadry
    Citation: BMC Endocrine Disorders 2022 22:287
    Content type: Research Published on:

  27. Previous studies have indicated an association between birth weight (BW) and type 2 diabetes mellitus (T2DM), but few studies have explored this relationship under different conditions of obesity in adulthood.

    Authors: Pu Song, Hui Hui, Manqing Yang, Peng Lai, Yan Ye, Ying Liu and Xuekui Liu
    Citation: BMC Endocrine Disorders 2022 22:285
    Content type: Research article Published on:

  28. To investigate whether exposure to systemic antibiotics influences the risk of developing type 2 diabetes and overweight/obesity.

    Authors: Joel Nuotio, Teemu Niiranen, Tomi T. Laitinen, Jessica Miller, Matthew A. Sabin, Aki S. Havulinna, Jorma S. A. Viikari, Tapani Rönnemaa, Nina Hutri-Kähönen, Tomi P. Laitinen, Päivi Tossavainen, Veikko Salomaa, Olli T. Raitakari, David P. Burgner and Markus Juonala
    Citation: BMC Endocrine Disorders 2022 22:284
    Content type: Research Published on:

  29. People living with type 1 diabetes (PWT1D) are at increased risk for impairments in brain function, which may impact on daily life. Cognitive impairments in PWT1D might contribute to increasing eating disorder...

    Authors: Sylvain Iceta, Léonie Sohier, Catherine Bégin, Anne-Sophie Brazeau, Rémi Rabasa-Lhoret and Claudia Gagnon
    Citation: BMC Endocrine Disorders 2022 22:283
    Content type: Study protocol Published on:

  30. To evaluate the association of vitamin D and thyroid-stimulating hormone (TSH) with weight loss (WL) percentage (%) in patients with diabetes/prediabetes and Class II/III obesity.

    Authors: Kemal Ağbaht and Serhan Vahit Pişkinpaşa
    Citation: BMC Endocrine Disorders 2022 22:282
    Content type: Research article Published on:

  31. Irisin is a novel myokine both in mice and humans, and it can also be secreted by adipose tissue and the liver in a small amounts. There are few studies on irisin and bone metabolism. The aim of this study was...

    Authors: Junru Liu, Xing Wang, Dongmei Fan, Lina Sun, Weinan Zhang, Fuzai Yin and Bowei Liu
    Citation: BMC Endocrine Disorders 2022 22:281
    Content type: Research Published on:

  33. Coexistence of a catecholamine-secreting tumor and an adrenal cortical tumor is quite rare which makes both diagnosis and management challenging. The purpose of this article is to describe the presence of this...

    Authors: Yu-Chen Hsu, Cheng-Han Lee, Chen-Yu Chen and Chung-Jye Hung
    Citation: BMC Endocrine Disorders 2022 22:279
    Content type: Case report Published on:

  34. 22q11.2 deletion syndrome (DiGeorge syndrome) is associated with multiple organ dysfunctions such as cardiac defects, immunodeficiency, and hypoplasia of parathyroid glands. Moreover, the phenotype of 22q11.2 ...

    Authors: Xuelian Chen, Lichuan Yang, Jianwei Li and Huiwen Tan
    Citation: BMC Endocrine Disorders 2022 22:278
    Content type: Case report Published on:

  36. Type 2 diabetes mellitus (T2DM) and its related complications contribute to the high morbidity and mortality in worldwide. Skeletal muscle insulin resistance plays a critical role in the onset of T2DM due to t...

    Authors: Jianjuan Ke, Xiaohua Hu, Changhua Wang and Yemin Zhang
    Citation: BMC Endocrine Disorders 2022 22:276
    Content type: Research Published on:

  37. We aimed to explore descriptive epidemiology of T1 and T2 Diabetes Mellitus (DM) and to investigate demographic factors and comorbidities associated with all-cause mortality by aggregating and utilizing large-...

    Authors: Dinara Galiyeva, Arnur Gusmanov, Yesbolat Sakko, Alpamys Issanov, Kuralay Atageldiyeva, Kainar Kadyrzhanuly, Aiymzhan Nurpeissova, Marzhan Rakhimzhanova, Aigul Durmanova, Antonio Sarria-Santamera and Abduzhappar Gaipov
    Citation: BMC Endocrine Disorders 2022 22:275
    Content type: Research Published on:

  38. A novel non–insulin-based metabolic score for insulin resistance (METS‐IR) index has been proposed as a simple and reliable alternative insulin resistance (IR) marker, but its the predictive value in asymptoma...

    Authors: Zhenwei Wang, Xiaofang Hui, Xu Huang, Jingjie Li and Naifeng Liu
    Citation: BMC Endocrine Disorders 2022 22:274
    Content type: Research Published on:

  39. Depression is a risk factor for type 2 diabetes (T2D) and cardiovascular disease (CVD). The aims were to explore the prevalence of depression, anxiety, antidepressant use, obesity, Hemoglobin A1c > 64 mmol/mol...

    Authors: Eva O. Melin, Pär Wanby, Thomas Neumark, Sara Holmberg, Ann-Sofi Nilsson Neumark, Karin Johansson, Mona Landin-Olsson, Hans Thulesius, Magnus Hillman and Maria Thunander
    Citation: BMC Endocrine Disorders 2022 22:273
    Content type: Research Published on:

  40. We aimed to evaluate the performance of Chinese visceral adiposity index (CVAI), visceral adiposity index (VAI), lipid accumulation product (LAP), triglyceride glucose (TyG) as indices in screening abnormal gl...

    Authors: Qianqian Yin, Xiaonan Yan, Yijuan Cao and Jianhua Zheng
    Citation: BMC Endocrine Disorders 2022 22:272
    Content type: Research article Published on:

  42. Gallbladder stone diseases (GSD) is a main risk factor of gallbladder cancer (GBC). This study aimed to reveal their bridge to metabolic syndrome.

    Authors: Yong Wan, Jianqin Zhang, Min Chen, Mao Ma and Binwu Sheng
    Citation: BMC Endocrine Disorders 2022 22:270
    Content type: Research Published on:

  43. Machine learning was a highly effective tool in model construction. We aim to establish a machine learning-based predictive model for predicting the cervical lymph node metastasis (LNM) in papillary thyroid mi...

    Authors: Yanling Huang, Yaqian Mao, Lizhen Xu, Junping Wen and Gang Chen
    Citation: BMC Endocrine Disorders 2022 22:269
    Content type: Research Published on:

  44. The role of the Endocannabinoids (ECs) in insulin resistance, and their association with visceral obesity and metabolic profile have been studied extensively. Since the association between ECs and metabolic fa...

    Authors: Hadi Bazyar, Khadijeh Nasiri, Parisa Ghanbari, Elahe Mohammadi, Neda Lotfi Yagin, Maryam Khazdouz, Vahideh Aghamohammadi and Shafagh Ali Asgarzadeh
    Citation: BMC Endocrine Disorders 2022 22:268
    Content type: Research Published on:

  45. Research suggests that fibrinogen (Fib) is related to mild cognitive impairment (MCI) and diabetic peripheral neuropathy (DPN) and the risk of MCI in patients with DPN is greatly increased, although no studies...

    Authors: Yong Zhuang, Huibin Huang, Zhenfei Fu, Jinying Zhang and Qingyan Cai
    Citation: BMC Endocrine Disorders 2022 22:267
    Content type: Research Published on:

  46. Diabetic peripheral neuropathy (DPN), due to its potential for causing morbidity and disability from foot ulcers and amputations, is increasingly becoming a source of concern in Saudi Arabia and worldwide. How...

    Authors: Lukman Femi Owolabi, Mushabab Alghamdi, Bappa Adamu, Magaji Garba Taura, Abubakar Jibo, Mohammed Almansour, Saeed Naseer Alaklabi, Mohammed Ali Alghamdi, Yousef Ayesh Alotaibi, Isa Adamu Imam, Reda Abdelrazak, Ahmad Rafaat and Muktar Hassan Aliyu
    Citation: BMC Endocrine Disorders 2022 22:266
    Content type: Research Published on:

  47. Ovarian steroid cell tumors (SCTs), not otherwise specified (NOS), are rare, with few large studies. The purpose of this study was to analyze the clinical features, prognosis, and treatment choices for these p...

    Authors: Mengyan Lin, Kechun Bao, Lingjia Lu, Shuhang Xu, Yun Liang, Xiaodong Cheng and Fenfen Wang
    Citation: BMC Endocrine Disorders 2022 22:265
    Content type: Research Published on:

  48. Proneurotensin (Pro-NT) is a strong predictor of cardiometabolic disease including type 2 diabetes and obesity, however, the effect of lifestyle change on Pro-NT has not been investigated in this context. Midd...

    Authors: Louise Bennet, Ayesha Fawad, Joachim Struck, Sara Lönn Larsson, Andreas Bergmann and Olle Melander
    Citation: BMC Endocrine Disorders 2022 22:264
    Content type: Research Published on:

  49. The purpose of this study was to survey the associations of six single nucleotide polymorphisms (SNPs) in the TMOD1 and PTCSC2 genes with thyroid carcinoma (TC).

    Authors: Kaijun Tong, Chang Zhang, Tingting Yang, Rongbiao Guo, Xinyuan Wang, Renyang Guan and Tianbo Jin
    Citation: BMC Endocrine Disorders 2022 22:263
    Content type: Research Published on:

  50. Non-islet cell tumour hypoglycemia (NICTH) is rarely encountered in clinical practice. Insulin-like growth factor 2 (IGF2) is the most common cause of NICTH observed in the setting of mesenchymal and epithelia...

    Authors: Mairead T. Crowley, Eibhlin Lonergan, Peter O’Callaghan, Caroline M. Joyce, M. Morita, Niamh Conlon and Domhnall J. O’Halloran
    Citation: BMC Endocrine Disorders 2022 22:262
    Content type: Case report Published on:
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BMC Endocrine Disorders

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