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  1. Caveolin-1 (CAV-1) is a cholesterol-dependent essential component located in caveolae. Several studies have been CAV-1 related to cardio-metabolic parameters in animal models, however, there are few studies in...

    Authors: Faezeh Abaj, Fariba Koohdani, Masoumeh Rafiee, Ehsan Alvandi, Mir Saeed Yekaninejad and Khadijeh Mirzaei
    Citation: BMC Endocrine Disorders 2021 21:138
  2. Management of primary aldosteronism (PA) has become a research hotspot in the field of endocrinology. To obtain reliable research evidence, it is necessary to establish a high-quality PA research database.

    Authors: Wen Wang, Yuanmei Li, Qianrui Li, Tingting Zhang, Wei Wang, Dan Mo, Haoming Tian, Tao Chen and Yan Ren
    Citation: BMC Endocrine Disorders 2021 21:137
  3. This study aims to explore the correlation between procalcitonin (PCT), 25-hydroxyvitamin D3 (25(OH)D), pentraxin-3 (PTX-3), amylase (AMS) levels and severity of diabetic ketoacidosis complicated by pancreatitis.

    Authors: Songtao Lu, Dongmei Wei, Chao Yin, Juwen Xiong, Lishuang Zhu, Shaoru Yan and Rui Meng
    Citation: BMC Endocrine Disorders 2021 21:136
  4. The Middle East and North Africa (MENA) is postulated to have the highest increase in the prevalence of diabetes by 2030; however, studies on the epidemiology of diabetes are rather limited across the region, ...

    Authors: Sanam Hariri, Zahra Rahimi, Nahid Hashemi-Madani, Seyyed Ali Mard, Farnaz Hashemi, Zahra Mohammadi, Leila Danehchin, Farhad Abolnezhadian, Aliasghar Valipour, Yousef Paridar, Mohammad Mahdi Mir-Nasseri, Alireza Khajavi, Sahar Masoudi, Saba Alvand, Bahman Cheraghian, Ali Akbar Shayesteh…
    Citation: BMC Endocrine Disorders 2021 21:135
  5. Long non-coding RNAs (lncRNAs) are widely reported to be involved in the development of human diseases. HLA complex P5 (HCP5) deregulation is associated with various diseases. However, the function of HCP5 in ...

    Authors: Xuan Wang, Yan Liu, Jian Rong and Kai Wang
    Citation: BMC Endocrine Disorders 2021 21:134
  6. To evaluate the effect of nicotinamide prior to streptozotocin-induced (STZ) diabetes in baroreflex sensitivity and cardiovascular autonomic modulation, and its association with hemodynamics and metabolic para...

    Authors: Paula L. Cruz, Ivana C. Moraes-Silva, Amanda A. Ribeiro, Jacqueline F. Machi, Marcelo Dantas Tavares de Melo, Fernando dos Santos, Maikon Barbosa da Silva, Celia Maria Cassaro Strunz, Elia Garcia Caldini and Maria-Claudia Irigoyen
    Citation: BMC Endocrine Disorders 2021 21:133
  7. Thyrotoxicosis is the state of thyroid hormone excess. But, in sub-Saharan Africa (SSA), specifically Northern Ethiopia, scientific evidence about thyrotoxicosis and its cardiac complications like dilated card...

    Authors: Bisrat Tesfay Abera, Merhawit Atsbha Abera, Gebretsadik Berhe, Girmatsion Fisseha Abreha, Hirut Teame Gebru, Hiluf Ebuy Abraha and Mohamedawel Mohamedniguss Ebrahim
    Citation: BMC Endocrine Disorders 2021 21:132
  8. Hypertension and overweight are independent risk factors for cardiovascular disease, and overweight increase the risk of developing high blood pressure. ERBB3( also known as HER3) plays a considerable role in ...

    Authors: Lijun Zhu, Zhengmei Fang, Yuelong Jin, Weiwei Chang, Mengyun Huang, Yan Chen and Yingshui Yao
    Citation: BMC Endocrine Disorders 2021 21:130
  9. MYL-1501D is a proposed biosimilar to insulin glargine. The noninferiority of MYL-1501D was demonstrated in patients with type 1 diabetes and type 2 diabetes in 2 phase 3 trials. Immunogenicity of MYL-1501D an...

    Authors: Bin Sun, Nilanjan Sengupta, Anita Rao, Charles Donnelly, Vinit Waichale, Arnab Sinha Roy, Shilpa Ramaswamy, Divya Pathak, Ronald R. Bowsher, Yaron Raiter, Patrick Aubonnet and Abhijit Barve
    Citation: BMC Endocrine Disorders 2021 21:129
  10. Achieving an optimal glycemic control has been described to reduce the incidence of diabetes mellitus (DM) related complications. The association between comorbidities and glycemic control remains unclear. Our...

    Authors: Manuel Urina-Jassir, Lina Johana Herrera-Parra, Juliana Alexandra Hernández Vargas, Ana María Valbuena-García, Lizbeth Acuña-Merchán and Miguel Urina-Triana
    Citation: BMC Endocrine Disorders 2021 21:128
  11. Several new antidiabetic medicines (GLP-1 receptor agonists, DPP-4 inhibitors, and SGLT-2 inhibitors) have been approved by the European Medicines Agency since 2006. The aim of this study was to evaluate the u...

    Authors: Nika Mardetko, Urska Nabergoj Makovec, Igor Locatelli, Andrej Janez and Mitja Kos
    Citation: BMC Endocrine Disorders 2021 21:127
  12. Evaluation of vitamin D supplementation on ovarian reserve in women with diminished ovarian reserve and vitamin D deficiency.

    Authors: Shahintaj Aramesh, Touran Alifarja, Ramin Jannesar, Parvin Ghaffari, Raziyeh Vanda and Fatemeh Bazarganipour
    Citation: BMC Endocrine Disorders 2021 21:126
  13. Non-alcoholic fatty liver disease (NAFLD) is a common disorder that is known to be the leading cause of chronic liver disease worldwide. This study aims to systematically review and meta-analyze the associatio...

    Authors: Nader Salari, Niloufar Darvishi, Kamran Mansouri, Hooman Ghasemi, Melika Hosseinian-Far, Fateme Darvishi and Masoud Mohammadi
    Citation: BMC Endocrine Disorders 2021 21:125
  14. Although there is abundant evidence indicating the relative contribution of insulin resistance (HOMA-IR) and β-cell dysfunction (HOMA-β) among first-degree relatives (FDRs) of Type 2 DM patients, few studies r...

    Authors: Fahd Ahmed, Molham AL-Habori, Ebtesam Al-Zabedi and Riyadh Saif-Ali
    Citation: BMC Endocrine Disorders 2021 21:124
  15. Diabetes is a well-known risk factor for tuberculosis and poorly glycemic control may increase the risk of tuberculosis. We performed a meta-analysis to explore the association of glycemic control in diabetic ...

    Authors: Zhifei Chen, Qi Liu, Ranran Song, Wenxin Zhang, Tingping Wang, Zhan Lian, Xuezhi Sun and Yanli Liu
    Citation: BMC Endocrine Disorders 2021 21:123
  16. Treatment of diabetes mellitus has majorly improved over the past century, however, the disease burden is high and its prevalence still expanding. Further insight in the diabetes population is imperative to im...

    Authors: Jessica C. G. Bak, Dick Mul, Erik H. Serné, Harold W. de Valk, Theo C. J. Sas, Petronella H. Geelhoed-Duijvestijn, Mark H. H. Kramer, Max Nieuwdorp and Carianne L. Verheugt
    Citation: BMC Endocrine Disorders 2021 21:122
  17. Previous studies have indicated that women with a history of menstrual disorders have an increased risk of metabolic and cardiovascular diseases. This has been attributed to the high proportion of polycystic o...

    Authors: Saisai Li, Linjuan Ma, Yang Song, Jiehong Zheng, Yuqun Cai, Hong Xu, Peiqiong Chen, Wenxian Xu, Yizhou Huang, Tongyun Qi, Chunming Li, Ketan Chu, Yibing Lan, Ling Xu and Jianhong Zhou
    Citation: BMC Endocrine Disorders 2021 21:121
  18. Gestational diabetes mellitus (GDM) is associated with increased risks of disease for mother and child during pregnancy and after that. Early diagnosis of GDM would promote both maternal and fetal health. Meta...

    Authors: Shaghayegh Hosseinkhani, Hojat Dehghanbanadaki, Hossein Aazami, Parvin Pasalar, Mojgan Asadi and Farideh Razi
    Citation: BMC Endocrine Disorders 2021 21:120
  19. Most patients with congenital adrenal hypoplasia (AHC) develop symptoms during infantile and juvenile periods, with varying clinical manifestations. AHC is a disease that is easily misdiagnosed as Addison’s di...

    Authors: Hong Ouyang, Bo Chen, Na Wu, Ling Li, Runyu Du, Meichen Qian, Wenshu Yu, Yujing He and Xinyan Liu
    Citation: BMC Endocrine Disorders 2021 21:118
  20. Although diabetes is one of the fastest increasing diseases in prevalence worldwide and demands significant medical resources, more than half of all patients with diabetes do not achieve the expected target le...

    Authors: Yoshiko Tominaga, Donald E. Morisky and Mayumi Mochizuki
    Citation: BMC Endocrine Disorders 2021 21:117
  21. Transsphenoidal surgery (TSS) remains the treatment of choice for non-functioning pituitary macroadenomas (NFPMA). The value of measuring tumour volumes before and after surgery, and its influence on endocrine...

    Authors: K. Seejore, S. A. Alavi, S. M. Pearson, J. M. W. Robins, B. Alromhain, A. Sheikh, P. Nix, T. Wilson, S. M. Orme, A. Tyagi, N. Phillips and R. D. Murray
    Citation: BMC Endocrine Disorders 2021 21:116
  22. Tamoxifen, which is one of the selective estrogen receptor modulators (SERMs), can bring out life-threatening complication, e.g. hypertriglyceridemia-induced acute pancreatitis, although it is rare. We precise...

    Authors: Hayato Isobe, Masashi Shimoda, Yuki Kan, Fuminori Tatsumi, Yukino Katakura, Tomohiko Kimura, Atsushi Obata, Kenji Kohara, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku and Hideaki Kaneto
    Citation: BMC Endocrine Disorders 2021 21:115
  23. Primary aldosteronism (PA) is highly prevalent in hypertensive population. Adrenal vein sampling (AVS) is the only procedure to assess adrenal aldosterone hypersecretion in PA. PA patients without aldosterone-...

    Authors: Fang Sun, Yangning Hong, Hexuan Zhang, Xiaoli Liu, Zhigang Zhao, Hongbo He, Zhencheng Yan and Zhiming Zhu
    Citation: BMC Endocrine Disorders 2021 21:114
  24. There are insufficient data in case of the potential association of habitual dietary L-arginine and the risk of type 2 diabetes mellitus (T2DM) incidence. Here we aimed to examine the potential effect of dieta...

    Authors: Parvin Mirmiran, Zahra Bahadoran, Zahra Gaeini and Fereidoun Azizi
    Citation: BMC Endocrine Disorders 2021 21:113
  25. Few studies have focused on the association between lifestyle and subclinical hypothyroidism (SCH). The purpose of this study was to investigate the association between lifestyle and thyroid function in SCH.

    Authors: Kejun Wu, Yu Zhou, Sujie Ke, Jingze Huang, Xuelin Gao, Beibei Li, Xiaoying Lin, Xiaohong Liu, Xiaoying Liu, Li Ma, Linxi Wang, Li Wu, Lijuan Wu, Chengwen Xie, Junjun Xu, Yanping Wang…
    Citation: BMC Endocrine Disorders 2021 21:112
  26. Low free triiodothyronine (FT3) levels are related to a poor prognosis deterioration in patients with COVID-19 presenting with non-thyroidal illness syndrome (NTI). This study was designed to explore whether f...

    Authors: Jing Gong, Ding-kun Wang, Hui Dong, Qing-song Xia, Zhao-yi Huang, Yan Zhao, Xing Chen, Fen Yuan, Jing-bin Li and Fu-er Lu
    Citation: BMC Endocrine Disorders 2021 21:111
  27. Patients with growth hormone (GH)-secreting adenoma usually develop glucose intolerance. GH increases metabolic rate and, when secreted aberrantly, may result in metabolic syndrome. Herein, we examine the asso...

    Authors: JinYu Pan, XiangHong Yang and Wei Zhu
    Citation: BMC Endocrine Disorders 2021 21:109
  28. Thyroid autoimmunity(TAI) is the most prevalent autoimmune condition in women of fertile age. There are increasing data regarding the association of thyroid dysfunction and thyroid autoimmunity with adverse pr...

    Authors: Batul Birjandi, Fahimeh Ramezani Tehrani, Atieh Amouzegar, Maryam Tohidi, Razieh Bidhendi Yarandi and Feriedoun Azizi
    Citation: BMC Endocrine Disorders 2021 21:108
  29. The prevalence of obesity is considered to be increased worldwide. Lack of mineral elements is one of the essential side effects of bariatric surgery as a trending treatment for obesity. We aimed to assess zin...

    Authors: Fahimeh Soheilipour, Mohammad Ebrahimian, Mohadeseh Pishgahroudsari, Maryam Hajian, Davoud Amirkashani, Mahtab Ordooei, Mohammad Radgoodarzi and Delaram Eskandari
    Citation: BMC Endocrine Disorders 2021 21:107
  30. The effects of vitamin and mineral supplementation on women with gestational diabetes mellitus (GDM) have not been well established. We conduct a meta-analysis to evaluate the effects of vitamin and mineral su...

    Authors: Dandan Li, Zixin Cai, Zhenhong Pan, Yan Yang and Jingjing Zhang
    Citation: BMC Endocrine Disorders 2021 21:106
  31. The best HbA1c test interval strategy for detecting new type 2 diabetes mellitus (T2DM) cases in healthy individuals should be determined with consideration of HbA1c test characteristics, risk stratification t...

    Authors: Sachiko Ohde, Kensuke Moriwaki and Osamu Takahashi
    Citation: BMC Endocrine Disorders 2021 21:105
  32. Normoalbuminuric diabetic kidney disease (NADKD) is a newly defined DKD, the clinical features and pathogenesis for which are still being understood. This study aimed to investigate the features and risk facto...

    Authors: Qi Dai, Nan Chen, Ling Zeng, Xin-Jie Lin, Feng-Xiu Jiang, Xiong-Jie Zhuang and Ze-Yuan Lu
    Citation: BMC Endocrine Disorders 2021 21:104
  33. Pseudohypoaldosteronism type II (PHAII), also called Gordon syndrome, is a rare hereditary disease caused by variants in the WNK1, WNK4, KLHL3 and CUL3 genes. The combination of PHAII with hyperthyroidism and sec...

    Authors: Rui Zhang, Simin Zhang, Yingying Luo, Meng Li, Xin Wen, Xiaoling Cai, Xueyao Han and Linong Ji
    Citation: BMC Endocrine Disorders 2021 21:103
  34. The purpose of this study was to investigate the application value of serum 25(OH)D3, uric acid, triglyceride (TG), and homeostasis model assessment of insulin resistance (HOMA-IR) in male patients with hyperu...

    Authors: Qun Zhang, Wei Chen, Canqin Yun and Juan Wang
    Citation: BMC Endocrine Disorders 2021 21:102
  35. This study estimated the incidence of major amputation for people in North Queensland, Australia, examined changes in amputation rates over time and investigated survival after major amputation.

    Authors: Tejas P. Singh, Joseph V. Moxon, Michael T. Meehan, Rhondda Jones, Yvonne Cadet-James and Jonathan Golledge
    Citation: BMC Endocrine Disorders 2021 21:101
  36. It is widely acknowledged that nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus(T2DM) are all chronic metabolic diseases. The objective of this study is to retrospectively probe the associ...

    Authors: Yuanyuan Zhang, Juyi Li, Yingqun Ni, Yan Wang and Huaizhen Liu
    Citation: BMC Endocrine Disorders 2021 21:100
  37. Diet is central to the management of type 2 diabetes mellitus (T2DM). Depending on the stage of the disease at which the recommended diet is initiated, optimal adherence can reduce HbA1c by about 1 to 2%. Howe...

    Authors: Hagos Amare Gebreyesus, Girmatsion Fisseha Abreha, Sintayehu Degu Besherae, Merhawit Atsbha Abera, Abraha Hailu Weldegerima, Eshetu Girma Kidane, Afework Mulugeta Bezabih, Tefera Belachew Lemma and Tsinuel Girma Nigatu
    Citation: BMC Endocrine Disorders 2021 21:99
  38. Manifestations of hypokalaemia in ectopic adrenocorticotropic hormonesyndrome(EAS) vary from mild muscle weakness to life-threatening arrhythmia. Herein, we present a rare case of EAS with concomitant rhabdomy...

    Authors: Wei Qiang, Sucai Song, Tianjun Chen, Zhe Wang, Jun Feng, Jiaojiao Zhang and Hui Guo
    Citation: BMC Endocrine Disorders 2021 21:98
  39. Hyperuricemia has attracted increasing attention. However, limited concern has been paid to the potential dangers of lowering serum uric acid (SUA). We observed lower levels of SUA in patients with COVID-19. T...

    Authors: Fang Hu, Yifan Guo, Jianghong Lin, Yingjuan Zeng, Juan Wang, Man Li and Li Cong
    Citation: BMC Endocrine Disorders 2021 21:97
  40. Mental health problems are highly prevalent in people with type 1 diabetes mellitus (T1DM), which adversely impact physical health and quality of life. This study aimed to explore the experiences of people wit...

    Authors: Lucienne Ferrier, Chantal F. Ski, Casey O’Brien, Zoe Jenkins, David R. Thompson, Gaye Moore, Glenn Ward and David J. Castle
    Citation: BMC Endocrine Disorders 2021 21:96
  41. Uric acid has strong antioxidant activity, whereas its oxidative damage is closely related to many diseases. We assessed the association between serum uric acid (SUA) levels and premature rupture of membranes ...

    Authors: Meixiang Guo, Jun Lu, Xuemei Yu, Xiaowen Hu, Wenjing Hou and Shuguang Pang
    Citation: BMC Endocrine Disorders 2021 21:95
  42. Recent studies have reported that HbA1c and lipid variability is useful for risk stratification in diabetes mellitus. The present study evaluated the predictive value of the baseline, subsequent mean of at lea...

    Authors: Sharen Lee, Jiandong Zhou, Wing Tak Wong, Tong Liu, William K. K. Wu, Ian Chi Kei Wong, Qingpeng Zhang and Gary Tse
    Citation: BMC Endocrine Disorders 2021 21:94
  43. Patients with Crooke cell tumours present with features of Cushing syndrome or mass effect. There are few reports of patients with Crooke cell tumours presenting due to apoplexy. All of them had silent tumours...

    Authors: Nipun Lakshitha de Silva, Noel Somasundaram, Roshana Constantine and Himashi Kularatna
    Citation: BMC Endocrine Disorders 2021 21:93
  44. The prevalence of diabetes is increasing worldwide. Our study aimed to estimate the changing trends in the prevalence and incidence of diagnosed type 2 diabetes mellitus (T2DM) among Xiamen residents and the f...

    Authors: Weiwei He, Qiushi Xu, Lili Han, Ting Wu, Xiulin Shi, Lishan Ye, Guanhua Yao and Xuejun Li
    Citation: BMC Endocrine Disorders 2021 21:92
  45. Although many studies on non-alcoholic fatty liver disease (NAFLD) are underway worldwide, and several existing studies have investigated the association between NAFLD and cardiovascular risk factors, studies ...

    Authors: A. L. Han
    Citation: BMC Endocrine Disorders 2021 21:91
  46. Hypercalcemia associated with acromegaly is mostly parathyroid hormone (PTH)-dependent, being caused by parathyroid hyperplasia or adenoma, which are common in individuals with multiple endocrine adenomatosis-...

    Authors: Shaomin Shi, Lan Zhang, Yerong Yu, Chun Wang and Jianwei Li
    Citation: BMC Endocrine Disorders 2021 21:90
  47. Due to the increasing worldwide prevalence of obesity, it is essential to determine the prevalence of obesity-related thyroid dysfunctions. The purpose of this study was to investigate the prevalence of thyroi...

    Authors: Mahdi Mahdavi, Atieh Amouzegar, Ladan Mehran, Elham Madreseh, Maryam Tohidi and Fereidoun Azizi
    Citation: BMC Endocrine Disorders 2021 21:89

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