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  1. Among patients with type 2 diabetes, insulin intensification to achieve glycemic targets occurs less often than clinically indicated. Barriers to intensification are not well understood. We present patients’ b...

    Authors: Jennifer M. Polinski, Seoyoung C. Kim, Dingfeng Jiang, Ahmed Hassoun, William H. Shrank, Xavier Cos, Efraín Rodríguez-Vigil, Shuichi Suzuki, Ikuro Matsuba, John D. Seeger, Wesley Eddings, Gregory Brill and Bradley H. Curtis
    Citation: BMC Endocrine Disorders 2015 15:46
    Content type: Research article Published on:

  2. China is one of the countries with the highest prevalence of diabetes in the world. We analysed all the death certificates mentioning diabetes from 2002 to 2012 in Songjiang District of Shanghai to estimate mo...

    Authors: Meiying Zhu, Jiang Li, Zhiyuan Li, Wei Luo, Dajun Dai, Scott R. Weaver, Christine Stauber, Ruiyan Luo and Hua Fu
    Citation: BMC Endocrine Disorders 2015 15:45
    Content type: Research article Published on:

  4. Problematic hypoglycaemia is a significant problem among people with insulin-treated type 1 and 2 diabetes mellitus, which adversely affects quality of life and leads to high societal costs. Blood glucose awar...

    Authors: Stefanie MPA Rondags, Maartje de Wit, Maurits W van Tulder, Michaela Diamant and Frank J. Snoek
    Citation: BMC Endocrine Disorders 2015 15:43
    Content type: Study protocol Published on:

  5. Hypoglycemia is the main side effect of intensified insulin therapy in type 1 diabetes and recognized as a limitation in achieving glycemic targets. Patients with impaired awareness of hypoglycemia have a thre...

    Authors: Cornelis A.J. van Beers, Susanne J. Kleijer, Erik H. Serné, Petronella H. Geelhoed-Duijvestijn, Frank J. Snoek, Mark H.H. Kramer and Michaela Diamant
    Citation: BMC Endocrine Disorders 2015 15:42
    Content type: Study protocol Published on:

  6. Non-alcoholic fatty liver disease (NAFLD) is one of the most common disorders of the liver worldwide. Recently, a correlation between thyroid dysfunction and NAFLD has been discussed. Objective of the present ...

    Authors: Ulla Ludwig, Daniela Holzner, Christian Denzer, Artur Greinert, Mark Martin Haenle, Suemeyra Oeztuerk, Wolfgang Koenig, Bernhard Otto Boehm, Richard Andrew Mason, Wolfgang Kratzer and Tilmann Graeter
    Citation: BMC Endocrine Disorders 2015 15:41
    Content type: Research article Published on:

  7. The association between mesotheliomas and ectopic ACTH secretion has been rarely reported; we present the first case of ectopic ACTH secretion (EAS) associated with a well-differentiated peritoneal mesotheliom...

    Authors: Carmen F. Mendoza, Patricia Ontiveros, Daniel X. Xibillé and Manuel H. Rivera
    Citation: BMC Endocrine Disorders 2015 15:40
    Content type: Case report Published on:

    The Erratum to this article has been published in BMC Endocrine Disorders 2015 15:48

  8. Mazabraud’s syndrome is defined as the association between fibrous dysplasia and intramuscular myxomas. The syndrome was first described in 1967 and, up until now, less than 100 cases have been reported worldw...

    Authors: Doina Piciu, Elena Barbus, Andra Piciu and Bogdan Fetica
    Citation: BMC Endocrine Disorders 2015 15:39
    Content type: Case report Published on:

  9. Gestational diabetes mellitus (GDM) is associated with adverse pregnancy outcomes such as preeclampsia and macrosomia. Women with polycystic ovary syndrome (PCOS) are at increased risk of developing GDM. Today...

    Authors: Ingrid Hov Odsæter, Arne Åsberg, Eszter Vanky and Sven Magnus Carlsen
    Citation: BMC Endocrine Disorders 2015 15:38
    Content type: Research article Published on:

  10. Lifestyle modification is fundamental to obesity treatment, but few studies have described the effects of structured lifestyle programmes specifically in bariatric patients. We sought to describe changes in an...

    Authors: Catherine Crowe, Irene Gibson, Katie Cunningham, Claire Kerins, Caroline Costello, Jane Windle, Paula M. O′Shea, Mary Hynes, Brian McGuire, Katriona Kilkelly, Helena Griffin, Tim O′Brien, Jenni Jones and Francis M Finucane
    Citation: BMC Endocrine Disorders 2015 15:37
    Content type: Research article Published on:

  11. The pathogenesis of diabetic cardiomyopathy (DCM) involves the enhanced activation of peroxisome proliferator activating receptor (PPAR) transcription factors, including the most prominent isoform in the heart...

    Authors: Megan T. Quintana, Jun He, Jenyth Sullivan, Trisha Grevengoed, Jonathan Schisler, Yipin Han, Joseph A. Hill, Cecelia C. Yates, William E. Stansfield, Rudo F. Mapanga, M. Faadiel Essop, Michael J. Muehlbauer, Christopher B. Newgard, James R. Bain and Monte S. Willis
    Citation: BMC Endocrine Disorders 2015 15:36
    Content type: Research article Published on:

  12. The aim of the present study was to investigate the associations between endogenous testosterone concentrations and the incidence of acute myocardial infarction (AMI) in men and women with and without type 2 d...

    Authors: Bledar Daka, Robert D. Langer, Charlotte A. Larsson, Thord Rosén, Per Anders Jansson, Lennart Råstam and Ulf Lindblad
    Citation: BMC Endocrine Disorders 2015 15:35
    Content type: Research article Published on:

  13. There have only been a few reports about use of dipeptidyl peptidase 4 (DPP-4) inhibitors in elderly patients with type 2 diabetes mellitus (T2DM), suggesting that the safety of these agents has not been suffi...

    Authors: Shinichi Umezawa, Akira Kubota, Hajime Maeda, Akira Kanamori, Kiyokazu Matoba, Yasuyuki Jin, Fuyuki Minagawa, Mitsuo Obana, Kotaro Iemitsu, Shogo Ito, Hikaru Amamiya, Mizuki Kaneshiro, Masahiko Takai, Hideaki Kaneshige, Kazuhiko Hoshino, Masashi Ishikawa…
    Citation: BMC Endocrine Disorders 2015 15:34
    Content type: Research article Published on:

  14. Vitamin D deficiency is reported as a possible risk factor for the development of diabetes in several epidemiologic studies. In this study, we investigated the frequency of 25-OH vitamin D deficiency in type 2...

    Authors: Celil Alper Usluogullari, Fevzi Balkan, Sedat Caner, Rifki Ucler, Cafer Kaya, Reyhan Ersoy and Bekir Cakir
    Citation: BMC Endocrine Disorders 2015 15:33
    Content type: Research article Published on:

  15. There are several specific inflammatory and oxidative correlates among patients with hypothyroidism, but most studies are cross-sectional and do not evaluate the change in parameters during the treatment. The ...

    Authors: Roseane C. Marchiori, Luiz A. F. Pereira, Alexandre A. Naujorks, Diego L. Rovaris, Daiane F. Meinerz, Marta M. M. F. Duarte and João B. T. Rocha
    Citation: BMC Endocrine Disorders 2015 15:32
    Content type: Research article Published on:

  17. Pheochromocytoma and reninoma represent two rare diseases causing hypertension. We here reported a rare case of association between type 2 multiple endocrine neoplasia related bilateral pheochromocytoma and re...

    Authors: Rosa Maria Paragliola, Ettore Capoluongo, Francesco Torino, Angelo Minucci, Giulia Canu, Alessandro Prete, Alfredo Pontecorvi and Salvatore Maria Corsello
    Citation: BMC Endocrine Disorders 2015 15:30
    Content type: Case report Published on:

  18. While poor sleep quality can worsen cardiovascular risk factors such as glucose and lipid profiles in patients with type 2 diabetes mellitus (T2DM), the relationship between sleep quality and atherosclerosis r...

    Authors: Yusuke Osonoi, Tomoya Mita, Takeshi Osonoi, Miyoko Saito, Atsuko Tamasawa, Shiho Nakayama, Yuki Someya, Hidenori Ishida, Akio Kanazawa, Masahiko Gosho, Yoshio Fujitani and Hirotaka Watada
    Citation: BMC Endocrine Disorders 2015 15:29
    Content type: Research article Published on:

  19. Charcot osteoarthropathy or charcot foot is a rare, chronic, non-communicable condition of bones and joints which may results into severe deformity and more prone to develop ulcers possibly leading to amputati...

    Authors: Bilal Bin Younis, Adeela Shahid, Rozina Arshad, Saima Khurshid and Junaid Masood
    Citation: BMC Endocrine Disorders 2015 15:28
    Content type: Research article Published on:

  20. Cushing’s disease is very rare in the paediatric population. Although uncommon, corticotroph hyperplasia causing Cushing’s syndrome has been described in the adult population, but appears to be extremely rare ...

    Authors: E. Noctor, S. Gupta, T. Brown, M. Farrell, M. Javadpour, C. Costigan and A. Agha
    Citation: BMC Endocrine Disorders 2015 15:27
    Content type: Case report Published on:

  21. Associations between demographic data and pulmonary function have not been adequately examined in patients that underwent Roux-en-Y Gastric Bypass (RYGB). This study was designed to examine changes in body fat...

    Authors: Yinfang Tu, Haoyong Yu, Yuqian Bao, Pin Zhang, Jianzhong Di, Xiaodong Han and Weiping Jia
    Citation: BMC Endocrine Disorders 2015 15:26
    Content type: Research article Published on:

  23. Hypoxia inducible factor-1α (HIF-1α) is the central transcriptional regulator of hypoxic responses during the progression of pituitary adenomas. Although previous immunohistochemical studies revealed that HIF-...

    Authors: Chenran Zhang, Qiang Qiang, Ying Jiang, Liuhua Hu, Xuehua Ding, Yicheng Lu and Guohan Hu
    Citation: BMC Endocrine Disorders 2015 15:24
    Content type: Research article Published on:

  24. Patients with type-2 diabetes mellitus (T2DM) and hypertension have increased risk of cardiovascular disease (CVD). We studied individualized treatment targets and their achievement in clinical practice.

    Authors: Roland E Schmieder, Anselm K Gitt, Cornelia Koch, Peter Bramlage, Taoufik Ouarrak and Diethelm Tschöpe
    Citation: BMC Endocrine Disorders 2015 15:23
    Content type: Research article Published on:

  25. Continuous glucose monitoring (CGM) has revolutionised diabetes management. CGM enables complete visualisation of the glucose profile, and the uncovering of metabolic ‘weak points’. A standardised procedure to...

    Authors: Petra Augstein, Peter Heinke, Lutz Vogt, Roberto Vogt, Christine Rackow, Klaus-Dieter Kohnert and Eckhard Salzsieder
    Citation: BMC Endocrine Disorders 2015 15:22
    Content type: Research article Published on:

  26. To explore clinical characteristics and beta cell function in Chinese patients with newly diagnosed drug naive type 2 diabetes mellitus (T2DM) with different levels of serum triglyceride (TG).

    Authors: Shuang Zheng, Huan Zhou, Tingting Han, Yangxue Li, Yao Zhang, Wei Liu and Yaomin Hu
    Citation: BMC Endocrine Disorders 2015 15:21
    Content type: Research article Published on:

  27. Psychosocial problems are common in patients with diabetes. However, data on psychosocial issues affecting patients with diabetes in Zambia are scarce. The present study explored sources of stress, stress copi...

    Authors: Given Hapunda, Amina Abubakar, Fons van de Vijver and Frans Pouwer
    Citation: BMC Endocrine Disorders 2015 15:20
    Content type: Research article Published on:

  28. The hormone somatostatin inhibits growth hormone release from the pituitary gland and is theoretically linked to diabetes and diabetes related complications. This study aimed to investigate the relationship be...

    Authors: Peter R van Dijk, Gijs WD Landman, Larissa van Essen, Joachim Struck, Klaas H Groenier, Henk JG Bilo, Stephan JL Bakker and Nanne Kleefstra
    Citation: BMC Endocrine Disorders 2015 15:19
    Content type: Research article Published on:

  29. Primary care physicians (PCPs) are the main providers of diabetes care especially in resource-limited countries which experience extreme shortage of specialists. The present study aimed to evaluate PCPs’ appro...

    Authors: Ahmadou M Jingi, Jobert Richie N Nansseu and Jean Jacques N Noubiap
    Citation: BMC Endocrine Disorders 2015 15:18
    Content type: Research article Published on:

  30. Platelet hyperreactivity is a factor which contributes towards increased risk of cardiovascular events in adults with type 2 diabetes (T2DM). However, little is known about platelets’ disturbances among childr...

    Authors: Beata Malachowska, Bartlomiej Tomasik, Agnieszka Szadkowska, Anna Baranowska-Jazwiecka, Olga Wegner, Wojciech Mlynarski and Wojciech Fendler
    Citation: BMC Endocrine Disorders 2015 15:17
    Content type: Research article Published on:

  31. Primary hyperparathyroidism (PHPT) and metabolic syndrome (MS) have been independently related to cardiovascular morbidities, however this association is still controversial. Mexican population has a high prev...

    Authors: Victoria Mendoza-Zubieta, Gloria A Gonzalez-Villaseñor, Guadalupe Vargas-Ortega, Baldomero Gonzalez, Claudia Ramirez-Renteria, Moises Mercado, Mario A Molina-Ayala and Aldo Ferreira-Hermosillo
    Citation: BMC Endocrine Disorders 2015 15:16
    Content type: Research article Published on:

  32. Low-dose combined oral contraceptives (COCs) can interfere with bone mass acquisition during adolescence. This study aimed to evaluate bone mineral density (BMD) and bone mineral content (BMC) in female adoles...

    Authors: Talita Poli Biason, Tamara Beres Lederer Goldberg, Cilmery Suemi Kurokawa, Maria Regina Moretto, Altamir Santos Teixeira and Hélio Rubens de Carvalho Nunes
    Citation: BMC Endocrine Disorders 2015 15:15
    Content type: Research article Published on:

  33. Polycystic ovary syndrome (PCOS) is associated with obesity and increased cardiovascular (CV) risk markers. In this study our aim was to assess the effects of six months treatment with liraglutide 1.8 mg od on...

    Authors: Hassan Kahal, Ahmed Aburima, Tamas Ungvari, Alan S Rigby, Anne M Coady, Rebecca V Vince, Ramzi A Ajjan, Eric S Kilpatrick, Khalid M Naseem and Stephen L Atkin
    Citation: BMC Endocrine Disorders 2015 15:14
    Content type: Research article Published on:

  35. The concept is now emerging that higher thyroid-stimulating hormone (TSH) and lower thyroid hormone levels within the euthyroid range may adversely affect atherosclerosis. The aim of this study was to investig...

    Authors: Yun Zhang, Ping Lu, Ling Zhang and Xinhua Xiao
    Citation: BMC Endocrine Disorders 2015 15:12
    Content type: Research article Published on:

  36. Insulin resistance triggered by excess fat is a key pathogenic factor that promotes type 2 diabetes. Understanding molecular mechanisms of insulin resistance may lead to the identification of a novel therapeut...

    Authors: Andreas AK Tandelilin, Tetsuaki Hirase, Athanasius W Hudoyo, Jidong Cheng, Keiko Toyama, Hiroko Morisaki and Takayuki Morisaki
    Citation: BMC Endocrine Disorders 2015 15:11
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Endocrine Disorders 2015 15:80

  37. Anasarca in patients with lymphoma is a rare symptom. We report a patient with DLBCL associated with pituitary gland infiltration that was diagnosed based on significant anasarca.

    Authors: Ayako Kumabe, Tsuneaki Kenzaka, Yoshioki Nishimura, Masaki Aikawa, Masaki Mori and Masami Matsumura
    Citation: BMC Endocrine Disorders 2015 15:10
    Content type: Case report Published on:

  38. Insulin resistance (IR) plays a vital role in the pathogenesis of Type 2 Diabetes Mellitus (T2DM). The mechanism of IR may be associated with inflammation, whereas the neutrophil-lymphocyte ratio (NLR) is a ne...

    Authors: Meiqin Lou, Peng Luo, Ru Tang, Yixian Peng, Siyuan Yu, Wanjing Huang and Lei He
    Citation: BMC Endocrine Disorders 2015 15:9
    Content type: Research article Published on:

  39. Diabetic retinopathy (DR) is an important microvascular complication of diabetes with a high concordance rate in patients with diabetes. Inflammation is supposed to participate in the development of DR. This s...

    Authors: Danfeng Peng, Jie Wang, Rong Zhang, Shanshan Tang, Feng Jiang, Miao Chen, Jing Yan, Xue Sun, Tao Wang, Shiyun Wang, Yuqian Bao, Cheng Hu and Weiping Jia
    Citation: BMC Endocrine Disorders 2015 15:8
    Content type: Research article Published on:

  40. Evidence suggests that activation of κ-opioid receptor (KOR) by U50,488H exhibits potential cardiovascular protective properties. However, the effects of U50,488H on vascular dysfunction in diabetes mellitus (...

    Authors: Xuan Zhou, Dongjuan Wang, Yuyang Zhang, Jinxia Zhang, Dingcheng Xiang and Haichang Wang
    Citation: BMC Endocrine Disorders 2015 15:7
    Content type: Research article Published on:

  41. The prevailing view that advocates long-term hormonal follow-up of adrenal incidentalomas is currently under debate. The purpose of the present study was to examine all adrenal incidentalomas presented during ...

    Authors: Hannah Yeomans, Jan Calissendorff, Cristina Volpe, Henrik Falhammar and Buster Mannheimer
    Citation: BMC Endocrine Disorders 2015 15:6
    Content type: Research article Published on:

  42. Vitamin D deficiency reportedly is associated with type 2 diabetes (T2DM). We aim to examine whether 25-hydroxyvitamin D (25OHD) has clinically significant influence on hemoglobin glycation (HbA1c) and insulin...

    Authors: Jayesh J Sheth, Ankna Shah, Frenny J Sheth, Sunil Trivedi, Mamta Lele, Navneet Shah, Premal Thakor and Rama Vaidya
    Citation: BMC Endocrine Disorders 2015 15:5
    Content type: Research article Published on:

  44. Primary hyperparathyroidism (PHPT) is often found on routine blood tests, at a relatively asymptomatic stage. However many studies suggest different systemic effects related to PHPT, which could be enhanced by...

    Authors: Chiara Sabbadin, Gabriella Donà, Luciana Bordin, Maurizio Iacobone, Valentina Camozzi, Caterina Mian and Decio Armanini
    Citation: BMC Endocrine Disorders 2015 15:4
    Content type: Case report Published on:

  45. In the treatment of childhood type 1 diabetes, being aware of the parents’ fear of hypoglycemia is important, since the parents’ fear may influence the management of treatment and the children’s blood glucose ...

    Authors: Anne Haugstvedt, Tore Wentzel-Larsen, Morten Aarflot, Berit Rokne and Marit Graue
    Citation: BMC Endocrine Disorders 2015 15:2
    Content type: Research article Published on:

  46. The study of endogenous insulin secretion may provide relevant insight into the comparison of the natural history of adult onset latent autoimmune diabetes (LADA) with types 1 and 2 diabetes mellitus. The aim ...

    Authors: Marta Hernandez, Angels Mollo, Josep Ramon Marsal, Aureli Esquerda, Ismael Capel, Manel Puig-Domingo, Paolo Pozzilli, Alberto de Leiva and Didac Mauricio
    Citation: BMC Endocrine Disorders 2015 15:1
    Content type: Research article Published on:

  47. Galactorrhoea is a common clinical problem in endocrinology. Visual and auditory cues from the newborn are known to stimulate prolactin secretion in lactating women. However, hyperprolactinaemia and galactorrh...

    Authors: Harsha Dissanayake, Sisil Keerthisena, Chinthana Dematapitiya and Prasad Katulanda
    Citation: BMC Endocrine Disorders 2014 14:98
    Content type: Case report Published on:

  49. Insulin resistance is one of the hallmark manifestations of obesity and Type II diabetes and reversal of this pathogenic abnormality is an attractive target for new therapies for Type II diabetes. A recent rep...

    Authors: Jidong Cheng, Hiroko Morisaki, Keiko Toyama, Naomi Sugimoto, Takuya Shintani, Andreas Tandelilin, Tetsuaki Hirase, Edward W Holmes and Takayuki Morisaki
    Citation: BMC Endocrine Disorders 2014 14:96
    Content type: Research article Published on:

  50. Children whose mothers had low thyroid hormone levels during pregnancy have been reported to have decreased cognitive function. The reported research is part of the follow-on study of the Controlled Antenatal ...

    Authors: Charlotte Hales, Sue Channon, Peter N Taylor, Mohd S Draman, Ilaria Muller, John Lazarus, Ruth Paradice, Aled Rees, Dionne Shillabeer, John W Gregory, Colin M Dayan and Marian Ludgate
    Citation: BMC Endocrine Disorders 2014 14:95
    Content type: Study protocol Published on:
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BMC Endocrine Disorders

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