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  1. This study aimed to investigate the occurrence and risk factors of thyroid dysfunction (TD) in patients with chronic hepatitis C (CHC) infection in Taiwan.

    Authors: Yu-Kang Chang, Yuan-Tsung Tseng, Kou-Huang Chen and Kow-Tong Chen
    Citation: BMC Endocrine Disorders 2019 19:36
  2. Diabetes mellitus is a growing cause of disease burden globally. Its management is multifaceted, and adherence to pharmacotherapy is known to play a significant role in glycaemic control. Data on medication ad...

    Authors: Leopold Ndemnge Aminde, Maxime Tindong, Calypse A. Ngwasiri, Jeannine A. Aminde, Tsi Njim, Azingala Ajua Fondong and Noah Fongwen Takah
    Citation: BMC Endocrine Disorders 2019 19:35
  3. To compare neurocognitive functioning of Type 1 diabetic mellitus (T1DM) and healthy adults, and explore risk factors of cognitive dysfunction of T1DM patients, especially the association between cognitive imp...

    Authors: Xin Ding, Chen Fang, Xiang Li, Yong-Jun Cao, Qi-Lin Zhang, Yun Huang, Jian Pan and Xia Zhang
    Citation: BMC Endocrine Disorders 2019 19:34
  4. As a member of peroxiredoxin (PRX) family, PRX3 is predominantly located in mitochondria and plays an important role of free radical scavenging. Since a body of evidence demonstrated the involvement of PRX3 in...

    Authors: Hou-Li Liu, Tian-Tian Li, Ai-Qun Yu, Jingmin Li, Xiaoyan Li, Lianqin Li and Tomonori Kaifu
    Citation: BMC Endocrine Disorders 2019 19:32
  5. type 2 diabetes mellitus (T2DM) is a complicated disease that can affect bone health, but the change in bone biochemical markers caused by T2DM was controversial, so the aim of this study was to investigate wh...

    Authors: Lianzi Wang, Tao Li, Jiaqing Liu, Xian Wu, Huihui Wang, Xuemei Li, Enjun Xu, Qiuli Chen, Chuan Yan, Huimin Li, Yuanhong Xu and Wei Wei
    Citation: BMC Endocrine Disorders 2019 19:31
  6. Irregular menstruation is clinically associated with an increased risk for ovarian cancer and disease-related mortality. This relationship remains poorly understood, and a mechanism explaining it has yet to be...

    Authors: Jiao Jiao, Matthew Sagnelli, Bei Shi, Yuanyuan Fang, Ziqi Shen, Tianyu Tang, Bingying Dong, Da Li and Xiuxia Wang
    Citation: BMC Endocrine Disorders 2019 19:30
  7. To determine the relation between daily glycemic fluturation and the intestinal mucosal barrier dysfunction in type 2 diabetes mellitus (T2DM).

    Authors: Lijuan Shen, Li Ao, Haoben Xu, Junfeng Shi, Dali You, Xiuwen Yu, Weixin Xu, Jie Sun and Fei Wang
    Citation: BMC Endocrine Disorders 2019 19:29
  8. Although snoring has been previously reported to be associated with metabolic syndrome (MetS), its interaction with body mass index(BMI) on MetS remains unclear. We aimed to examine the individual effects and ...

    Authors: Yanyan Li, Qian Gao, Lu Li, Yanan Shen, Qing Lu, Jianjun Huang, Chenming Sun, Hui Wang, Nan Qiao, Cong Wang, Haixia Zhang and Tong Wang
    Citation: BMC Endocrine Disorders 2019 19:28
  9. Diabetes-related lower limb amputations (LLA) are associated with significant morbidity and mortality. Although the incidence has decreased over the past two decades in most High-Income Countries, the situatio...

    Authors: Osei Sarfo-Kantanka, Fred Stephen Sarfo, Ishmael Kyei, Charles Agyemang and Jean Claude Mbanya
    Citation: BMC Endocrine Disorders 2019 19:27
  10. Immune checkpoint inhibitors including nivolumab, an anti-programmed cell death protein 1 antibody, are recently developed cancer immunotherapy agents. Immune checkpoint inhibitors are known to cause autoimmun...

    Authors: Ayumu Takeno, Masahiro Yamamoto, Miwa Morita, Sayuri Tanaka, Ippei Kanazawa, Mika Yamauchi, Sakae Kaneko and Toshitsugu Sugimoto
    Citation: BMC Endocrine Disorders 2019 19:25
  11. Data of studies focusing on the trends of adiposity indices among women with prior gestational diabetes mellitus (GDM), are limited and controversial. The aim of this study was to compare overtime trends of ad...

    Authors: Samira Behboudi-Gandevani, Fahimeh Ramezani Tehrani, Maryam Rahmati, Mina Amiri and Fereidoun Azizi
    Citation: BMC Endocrine Disorders 2019 19:24
  12. Dysglycemic status defined by prediabetes and diabetes is known to be related with future risk of diabetic complications and cardiovascular diseases. Herein, we aimed to determine the diagnostic accuracy of gl...

    Authors: Yotsapon Thewjitcharoen, Amia Jones Elizabeth, Siriwan Butadej, Soontaree Nakasatien, Phawinpon Chotwanvirat, Ekgaluck Wanothayaroj, Sirinate Krittiyawong, Tinapa Himathongkam and Thep Himathongkam
    Citation: BMC Endocrine Disorders 2019 19:23
  13. As an insulin-dependent disease, type 1 diabetes requires paying close attention to the glycemic control. Studies have shown that mobile health (mHealth) can improve the management of chronic diseases. However...

    Authors: Xuemei Wang, Wei Shu, Jian Du, Maolin Du, Peiyu Wang, Mingming Xue, Huiqiu Zheng, Yufeng Jiang, Shaohua Yin, Danyan Liang, Ruiqi Wang and Lina Hou
    Citation: BMC Endocrine Disorders 2019 19:21
  14. Measurement of gylcated hemoglobin A1c (HbA1c) plays a central role in monitoring quality of antidiabetic therapy and in the diagnosis of diabetes. Several studies report increased levels of HbA1c in nondiabet...

    Authors: Annette Masuch, Nele Friedrich, Johannes Roth, Matthias Nauck, Ulrich Alfons Müller and Astrid Petersmann
    Citation: BMC Endocrine Disorders 2019 19:20
  15. Sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3) proteins have an important role in counteracting oxidative stress. Although diabetes and hypothyroidism (HT) are both characterized by oxidative stress, the mechanisms a...

    Authors: Abdullah Al-Khaldi and Samar Sultan
    Citation: BMC Endocrine Disorders 2019 19:19
  16. The incretin-based medicines GLP1 analogues (GLP1a) and dipeptidyl peptidase-4 inhibitors (DPP4i) are hypoglycaemic agents licensed for the treatment of type 2 diabetes mellitus (T2DM). Although these drugs po...

    Authors: Giuseppe Roberto, Francesco Barone-Adesi, Francesco Giorgianni, Valeria Pizzimenti, Carmen Ferrajolo, Michele Tari, Claudia Bartolini, Roberto Da Cas, Marina Maggini, Stefania Spila-Alegiani, Paolo Francesconi, Gianluca Trifirò, Elisabetta Poluzzi, Fabio Baccetti and Rosa Gini
    Citation: BMC Endocrine Disorders 2019 19:18
  17. Hypoglycemia presents a barrier to optimum diabetes management and it is related to a negative impact on health-related quality of life, healthcare resource use, and work productivity. Despite the fact that th...

    Authors: Gashayeneh Genetu Tiruneh, Nurilign Abebe and Getenet Dessie
    Citation: BMC Endocrine Disorders 2019 19:17
  18. Renal hyperparathyroidism is a common complication of chronic kidney disease (CKD) or end-stage renal disease (ESRD) characterized by elevated parathyroid hormone levels secondary to derangements in the homeos...

    Authors: Tsai-Sung Tai, Yueh-Han Hsu, Jia Ming Chang and Chien-Chin Chen
    Citation: BMC Endocrine Disorders 2019 19:16
  19. A comparative study of 11 β HSD 1 activity in type 2 diabetes mellitus subjects with respect to fasting blood glucose and other metabolic parameters was conducted.

    Authors: Ravindra Shukla, Asish Kumar Basu, Biplab Mandal, Pradip Mukhopadhyay, Animesh Maity, Satyam Chakraborty and Praveen Kumar Devrabhai
    Citation: BMC Endocrine Disorders 2019 19:15
  20. Increased urinary free cortisol in response to the oral administration of dexamethasone is a paradoxical reaction mainly reported in patients with primary pigmented nodular adrenocortical disease. Here, we des...

    Authors: Chihiro Sakaguchi, Kenji Ashida, Kenichi Kohashi, Kenji Ohe, Yoichi Fujii, Seiichi Yano, Yayoi Matsuda, Shohei Sakamoto, Ryuichi Sakamoto, Yoshinao Oda, Masatoshi Nomura and Yoshihiro Ogawa
    Citation: BMC Endocrine Disorders 2019 19:13
  21. Zinc-α2-glycoprotein (ZAG) is a recently novel lipolytic adipokine implicated in regulation of glucose and lipid metabolism in many metabolic disorders. In vitro and animal studies suggest that thyroid hormone...

    Authors: Xin-Hua Xiao, Xiao-Yan Qi, Jiao-Yang Li, Yi-Bing Wang, Ya-Di Wang, Zhe-Zhen Liao, Jing Yang, Li Ran, Ge-Bo Wen and Jiang-Hua Liu
    Citation: BMC Endocrine Disorders 2019 19:12
  22. Fasting plasma glucose (FPG) is the most commonly used screening tool for diabetes in Sri Lanka. Cut-off values from American Diabetes Association recommendations are adopted in the absence of local data. We a...

    Authors: G. W. Katulanda, P. Katulanda, C. Dematapitiya, H. A. Dissanayake, S. Wijeratne, M. H. R. Sheriff and D. R. Matthews
    Citation: BMC Endocrine Disorders 2019 19:11
  23. The most frequently used methods of assessing Graves’ orbithopathy (GO) include: Clinical Activity Score (CAS), ultrasonography (USG), computed tomography (CT), and magnetic resonance imaging (MRI). There exis...

    Authors: Piotr Szumowski, Saeid Abdelrazek, Łukasz Żukowski, Małgorzata Mojsak, Monika Sykała, Katarzyna Siewko, Katarzyna Maliszewska, Anna Popławska-Kita and Janusz Myśliwiec
    Citation: BMC Endocrine Disorders 2019 19:10
  24. Vitamin-D2 (D2) treatment has been associated with a decrease in 25-hydroxy (25(OH)) vitamin-D3 (D3) level, suggesting that D3 treatment would be preferred to raise total 25(OH) vitamin-D (D) level. We postula...

    Authors: Muhammad M. Hammami, Kafa Abuhdeeb, Safa Hammami and Ahmed Yusuf
    Citation: BMC Endocrine Disorders 2019 19:8
  25. The role of technology in the self-management of type 1 diabetes mellitus (T1DM) among children and young people is not well understood. Interventions should aim to improve key diabetes self-management behavio...

    Authors: Emily C. L. Knox, Helen Quirk, Cris Glazebrook, Tabitha Randell and Holly Blake
    Citation: BMC Endocrine Disorders 2019 19:7
  26. Metabolic syndrome (MetS) is a cluster of metabolic abnormalities that increases the cardiovascular risk. Regular physical exercise can promote benefits, but the MetS individuals are demotivated to perform it....

    Authors: Danúbia Sá-Caputo, Laisa Liane Paineiras-Domingos, Arlete Francisca-Santos, Elzi Martins dos Anjos, Aline Silva Reis, Mario Fritsch Toros Neves, Wille Oigman, Ricardo Oliveira, Andrea Brandão, Christiano Bittencourt Machado, Xavier Chiementin, Redha Taiar, Alessandro Sartório and Mario Bernardo-Filho
    Citation: BMC Endocrine Disorders 2019 19:6
  27. Insulin injection, especially with insulin analogs, occasionally induces the production of insulin antibodies with high binding capacity and low affinity, similar to the insulin autoantibodies characteristic o...

    Authors: Keizo Kaneko, Chihiro Satake, Tomohito Izumi, Mamiko Tanaka, Junpei Yamamoto, Yoichiro Asai, Shojiro Sawada, Junta Imai, Tetsuya Yamada and Hideki Katagiri
    Citation: BMC Endocrine Disorders 2019 19:5
  28. Several clinical trials have studied the effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs) on glycometabolism and cardiovascular risk factors since they were identified. Because of their cardiova...

    Authors: Xu Zhao, Kun Huang, Meijie Zheng and Junting Duan
    Citation: BMC Endocrine Disorders 2019 19:4
  29. Dipeptidyl peptidase-4 (DPP-4) inhibitors could effectively reduce HbA1C and postprandial hyperglycemia and could incur only minimal danger of hypoglycemia. Patients with uncontrolled diabetes might be treated by...

    Authors: Fu-Shun Yen, Jen-Huai Chiang, Chii-Min Hwu, Yu-Hsin Yen, Boniface J. Lin, James Cheng-Chung Wei and Chih-Cheng Hsu
    Citation: BMC Endocrine Disorders 2019 19:3
  30. Chronic diabetic complications may afflict all organ tissues, including those of the respiratory system. The six-minute walk test (6MWT) is an alternative and widely used method of assessing functional capacity a...

    Authors: Krzysztof Kuziemski, Wojciech Słomiński and Ewa Jassem
    Citation: BMC Endocrine Disorders 2019 19:2
  31. Diabetic foot ulcers (DFU) are a common problem in longstanding diabetes. However, mortality outcomes in Australian patients with DFU are still unclear.

    Authors: Kanakamani Jeyaraman, Thomas Berhane, Mark Hamilton, Abhilash P. Chandra and Henrik Falhammar
    Citation: BMC Endocrine Disorders 2019 19:1
  32. Insulinoma is a rare tumour representing 1–2% of all pancreatic neoplasms and it is malignant in only 10% of cases. Locoregional invasion or metastases define malignancy, whereas the dimension (> 2 cm), CK19 s...

    Authors: Mariasmeralda Caliri, Valentina Verdiani, Edoardo Mannucci, Vittorio Briganti, Luca Landoni, Alessandro Esposito, Giulia Burato, Carlo Maria Rotella, Massimo Mannelli and Alessandro Peri
    Citation: BMC Endocrine Disorders 2018 18:98
  33. Sub-Saharan Africa continues to face the highest rate of mortality from diabetes in the world due to limited access to quality diabetes care. We assessed the quality of diabetes care in a rural diabetes clinic...

    Authors: Sonak D. Pastakia, Bernardo Nuche-Berenguer, Chelsea Regina Pekny, Benson Njuguna, Elizabeth Guinevere O’Hara, Stephanie Y. Cheng, Jeremiah Laktabai, Victor Buckwalter, Nicholas Kirui and Patrick Chege
    Citation: BMC Endocrine Disorders 2018 18:97
  34. Growth hormone (GH) is a heterogeneous protein composed of several molecular isoforms, the most abundant ones being the 22 kDa- and 20 kDa-GH. Exercise-induced secretion of GH isoforms has been extensively inv...

    Authors: A. E. Rigamonti, M. Haenelt, M. Bidlingmaier, A. De Col, S. Tamini, G. Tringali, R. De Micheli, L. Abbruzzese, C. R. Goncalves da Cruz, M. Bernardo-Filho, S. G. Cella and A. Sartorio
    Citation: BMC Endocrine Disorders 2018 18:96
  35. Random glucose is widely measured in epidemiological studies and in the clinical setting when standardized fasting protocols and oral glucose tolerance testing or HbA1c measuring are not feasible. The relationshi...

    Authors: Jens Baumert, Christin Heidemann, Rebecca Paprott, Yong Du and Christa Scheidt-Nave
    Citation: BMC Endocrine Disorders 2018 18:95
  36. Hyponatraemia is the most common electrolyte disturbance amongst hospitalised patients. Both American and European guidelines recommend fluid restriction as first line treatment for SIADH, however differ on se...

    Authors: Kathryn Berkman, Kate Haigh, Ling Li, Jack Lockett, Goce Dimeski, Anthony Russell and Warrick J. Inder
    Citation: BMC Endocrine Disorders 2018 18:93
  37. Malignant insulinoma is extremely rare and accounts for only 10% of total insulinoma cases. The goal of this study is to retrospectively analyze clinical data from 15 patients with malignant insulinoma treated...

    Authors: Jie Yu, Fan Ping, Huabing Zhang, Wei Li, Tao Yuan, Yong Fu, Kai Feng, Weibo Xia, Lingling Xu and Yuxiu Li
    Citation: BMC Endocrine Disorders 2018 18:92
  38. Diabetes is a risk factor for cognitive impairment, but whether there is also a link between pre-diabetes and cognitive dysfunction is not yet fully established. The aim of this observational study was to inve...

    Authors: Elin Dybjer, Peter M. Nilsson, Gunnar Engström, Catherine Helmer and Katarina Nägga
    Citation: BMC Endocrine Disorders 2018 18:91
  39. Bariatric surgery is effective in remission of obesity comorbidities. This study was aimed at comparing CVD risk between morbidly obese patients with type 2 diabetes and pre-diabetes before and after bariatric...

    Authors: Matilde Rubio-Almanza, Rosa Cámara-Gómez, David Hervás-Marín, José Luis Ponce-Marco and Juan Francisco Merino-Torres
    Citation: BMC Endocrine Disorders 2018 18:90
  40. Alström syndrome (ALMS) is a very rare autosomal recessive monogenic disorder caused by a mutation in the ALMS1 gene and characterised by childhood onset obesity, dyslipidaemia, advanced non-alcoholic fatty liver...

    Authors: Shanat Baig, Vishy Veeranna, Shaun Bolton, Nicola Edwards, Jeremy W. Tomlinson, Konstantinos Manolopoulos, John Moran, Richard P. Steeds and Tarekegn Geberhiwot
    Citation: BMC Endocrine Disorders 2018 18:88
  41. Cognitive impairment is commonly observed in patients with Hashimoto thyroiditis (HT). Low levels of vitamin D have been correlated with cognitive impairment in non-HT population. We examined the association o...

    Authors: Jun Xu, Xiang-yun Zhu, Hui Sun, Xiao-qin Xu, Song-ao Xu, Yuan Suo, Li-jun Cao, Qiang Zhou, Hui-jie Yu and Wei-zhong Cao
    Citation: BMC Endocrine Disorders 2018 18:87
  42. Thyroid lymphomas are an exceptional finding in patients with thyroid nodules. Burkitt’s lymphoma is one of the rarest and most aggressive forms of thyroid lymphomas, and its prognosis depends on the earliness...

    Authors: Stella Bernardi, Andrea Michelli, Deborah Bonazza, Veronica Calabrò, Fabrizio Zanconati, Gabriele Pozzato and Bruno Fabris
    Citation: BMC Endocrine Disorders 2018 18:86
  43. After hormonal replacement therapy (HRT) including androgen replacement or sequential therapy of estrogen and progesterone, The combination of human chorionic gonadotropin (hCG) and human menopausal gonadotrop...

    Authors: Yinjie Gao, Bingqing Yu, Jiangfeng Mao, Xi Wang, Min Nie and Xueyan Wu
    Citation: BMC Endocrine Disorders 2018 18:85
  44. Soluble receptor for advanced glycation end-products (sRAGE) and advanced glycation end-products (AGE) have been associated with risks of cardiovascular disease. Because sRAGE is regarded as a scavenger to AGE...

    Authors: Kuang-Hsing Chiang, Jaw-Wen Chen, Shao-Sung Huang, Hsin-Bang Leu, Shing-Jong Lin and Po-Hsun Huang
    Citation: BMC Endocrine Disorders 2018 18:84

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