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  1. Barakat syndrome is an autosomal dominant rare genetic disease caused by haploinsufficiency of the GATA binding protein 3 (GATA3) gene. It is also known as HDR syndrome, and is characterized by varying degrees of...

    Authors: Anne D. D. Joseph, Nirmala D. Sirisena, Thirunavukarasu Kumanan, Vathualan Sujanitha, Veronika Strelow, Raina Yamamoto, Stefan Wieczorek and Vajira H. W. Dissanayake
    Citation: BMC Endocrine Disorders 2019 19:111
  2. Severe hypoglycaemia carries a significant risk of morbidity and mortality for people with type 1 diabetes. Economic costs are also high, estimated at approximately £13 million annually in England, UK. Continu...

    Authors: Parizad Avari, Rozana Ramli, Monika Reddy, Nick Oliver and Rachael Fothergill
    Citation: BMC Endocrine Disorders 2019 19:110
  3. Sarcopenia and sarcopenic obesity (SO) have a greater impact on the elderly. This study aimed to explore whether there were sex differences in the prevalence and adverse outcomes of sarcopenia and SO in commun...

    Authors: Yanping Du, Xiaodong Wang, Hua Xie, Songbai Zheng, Xiaoqing Wu, Xiaoying Zhu, Xuemei Zhang, Sihong Xue, Huilin Li, Wei Hong, Wenjing Tang, Minmin Chen, Qun Cheng and Jianqin Sun
    Citation: BMC Endocrine Disorders 2019 19:109
  4. The adipokine adipsin contributes to insulin resistance (IR), inflammation, and obesity, which are all regarded as high-risk factors for mild cognitive impairment (MCI) in patients with type 2 diabetes mellitu...

    Authors: Dan Guo, Yang Yuan, Rong Huang, Sai Tian, Jiaqi Wang, Hongyan Lin, Ke An, Jin Han and Shaohua Wang
    Citation: BMC Endocrine Disorders 2019 19:108
  5. Hypoglycemia is a common complication of insulin therapy in patients with Type 1 Diabetes Mellitus (DM). Awareness of hypoglycemic symptoms helps patients to recognize hypoglycemia and initiate self-treatment....

    Authors: Mohammad J. Alkhatatbeh, Nedaa A. Abdalqader and Mohammad A. Y. Alqudah
    Citation: BMC Endocrine Disorders 2019 19:107
  6. Lifestyle modification targeting weight management is the first-line treatment for women with Polycystic Ovary Syndrome (PCOS) regardless of presenting symptoms. Women with PCOS are more likely to gain more we...

    Authors: Siew Lim, Caroline A. Smith, Michael F. Costello, Freya MacMillan, Lisa Moran and Carolyn Ee
    Citation: BMC Endocrine Disorders 2019 19:106
  7. Clinical care of patients with cyclic Cushing’s syndrome (CS) is challenging. Classical pitfalls include incorrect subtyping, unnecessary surgical procedures and delayed definite treatment.

    Authors: Adriana Albani, Christina M. Berr, Felix Beuschlein, Marcus Treitl, Klaus Hallfeldt, Jürgen Honegger, Günter Schnauder and Martin Reincke
    Citation: BMC Endocrine Disorders 2019 19:105
  8. The relationship between breast cancer (BC) and thyroid disease (TD) is still controversial. The aim of the study was to investigate the possible coexistence of TD in patients with newly diagnosed BC and its c...

    Authors: Chiara Dobrinja, Serena Scomersi, Fabiola Giudici, Giulia Vallon, Alessio Lanzaro, Marina Troian, Deborah Bonazza, Andrea Romano, Fabrizio Zanconati, Nicolò de Manzini and Marina Bortul
    Citation: BMC Endocrine Disorders 2019 19:104
  9. Medullary thyroid carcinoma is a malignant uncommon and aggressive tumour of the parafollicular C cells. In about 75% of cases it is sporadic while, in case of RET mutation, it is associated to multiple endocr...

    Authors: Claudio Gambardella, Chiara Offi, Guglielmo Clarizia, Roberto Maria Romano, Immacolata Cozzolino, Marco Montella, Rosa Maria Di Crescenzo, Massimo Mascolo, Angelo Cangiano, Sergio Di Martino, Giancarlo Candela and Giovanni Docimo
    Citation: BMC Endocrine Disorders 2019 19:103
  10. The relationship between thyroid nodules (TNs) and adiposity is controversial. This paper describes a cross-sectional investigation performed to determine the existence of any such relationship. To assess adip...

    Authors: Hui-xia Yang, Yu Zhong, Wei-hua Lv, Feng Zhang and Hong Yu
    Citation: BMC Endocrine Disorders 2019 19:102
  11. Diabetes Mellitus is an increasingly prevalent chronic disease characterized by the body’s inability to metabolize glucose. The objective of this study was to build an effective predictive model with high sens...

    Authors: Hang Lai, Huaxiong Huang, Karim Keshavjee, Aziz Guergachi and Xin Gao
    Citation: BMC Endocrine Disorders 2019 19:101
  12. Abnormal levels of liver enzymes, particularly aminotransferases, are prognostic features of non-alcoholic fatty liver disease (NAFLD). Considering the important role of dietary intakes in development of NAFLD...

    Authors: Parvin Mirmiran, Zahra Gaeini, Zahra Bahadoran and Fereidoun Azizi
    Citation: BMC Endocrine Disorders 2019 19:100
  13. Glucagon stimulation test (GST) is often employed to assess the insulin reserve of the pancreatic beta cells in diabetic subjects. The clinical significance of the increment of plasma glucose (Δglucose) by exo...

    Authors: Yasutaka Takeda, Yukihiro Fujita, Ryoichi Bessho, Mao Sato, Tomoe Abe, Tsuyoshi Yanagimachi, Hidemitsu Sakagami, Atsuko Abiko, Yumi Takiyama, Tsuguhito Ota and Masakazu Haneda
    Citation: BMC Endocrine Disorders 2019 19:99
  14. To investigate the prevalence of cardiovascular disease (CVD) risk factors and assess the 10-year risk of CVD in non-menopausal and postmenopausal women with type 2 diabetes mellitus (T2DM).

    Authors: Huanhuan Zhou, Chenghuan Zhang, Jingyu Ni and Xiaoyun Han
    Citation: BMC Endocrine Disorders 2019 19:98
  15. Charcot neuropathic osteoarthropathy (CNO) is one of the most devastating complications of neuropathy in patients with diabetes. Establishing diagnosis of CNO is difficult, due to the lack of clear clinical an...

    Authors: C. V. Loupa, E. Meimeti, A. Kokas, E. D. Voyatzoglou and A. Donou
    Citation: BMC Endocrine Disorders 2019 19:96
  16. Cholecystectomy, central obesity, and insulin resistance (IR) are established risk factors for nonalcoholic fatty liver disease (NAFLD). We aimed to examine the relative contributions and combined association ...

    Authors: Wenzhu Yue, Xingxing Sun and Tingting Du
    Citation: BMC Endocrine Disorders 2019 19:95
  17. Acromegaly is highly associated with thyroid disorders. However, the clinical characteristics of thyroid nodules in individuals with acromegaly who present with thyroid diseases have not been completely elucid...

    Authors: Dianshuang Xu, Bolin Wu, Xiaoju Li, Yunjiu Cheng, Dubo Chen, Yuefeng Fang, Qiu Du, Zhiyong Chen and Xiaodong Wang
    Citation: BMC Endocrine Disorders 2019 19:94
  18. Obese women with polycystic ovary syndrome (PCOS) may face additional barriers in achieving weight loss. We aimed to compare the effects of the hypocaloric low glycemic index (LGI) diet on anthropometric varia...

    Authors: Farnaz Shishehgar, Parvin Mirmiran, Maryam Rahmati, Maryam Tohidi and Fahimeh Ramezani Tehrani
    Citation: BMC Endocrine Disorders 2019 19:93
  19. Hypertriglyceridemia is often observed as the result of lipid abnormality and frequently associated with other lipid and metabolic disorders. Aggravation of hypertriglyceridemia is caused by various conditions...

    Authors: Shintaro Irie, Takatoshi Anno, Fumiko Kawasaki, Ryo Shigemoto, Shuhei Nakanishi, Kohei Kaku and Hideaki Kaneto
    Citation: BMC Endocrine Disorders 2019 19:92
  20. In 2015 approximately 5.0 million people were estimated to have died from diabetes. Poor glycemic control is the most determinant of diabetes-related complication and death. The percentage of patients whose bl...

    Authors: Yitagesu Mamo, Fekede Bekele, Tadesse Nigussie and Ameha Zewudie
    Citation: BMC Endocrine Disorders 2019 19:91
  21. Endothelial cell-specific molecule-1 (ESM-1) is a biomarker associated with tumor progression in pituitary adenoma. We specifically focused on one type of pituitary adenoma, namely null cell adenoma (NCA) and ...

    Authors: Shousen Wang, Zhifeng Wu, Liangfeng Wei and Jianhe Zhang
    Citation: BMC Endocrine Disorders 2019 19:90
  22. Diabetes-related kidney disease is associated with end-stage renal disease and mortality, but opportunities remain to quantify its association with cardiovascular and non-cardiovascular morbidity outcomes.

    Authors: James B. Wetmore, Suying Li, Thanh G. N. Ton, Yi Peng, Michael K. Hansen, Cheryl Neslusan, Ralph Riley, Jiannong Liu and David T. Gilbertson
    Citation: BMC Endocrine Disorders 2019 19:89
  23. Glycosylated hemoglobin (HbA1c) has a detrimental impact on the myocardium with left ventricular (LV) diastolic dysfunction. Obesity is a risk factor of type 2 diabetes. To understand the relationships between...

    Authors: Xin Zuo, Xueting Liu, Runtian Chen, Huiting Ou, Jiabao Lai, Youming Zhang and Dewen Yan
    Citation: BMC Endocrine Disorders 2019 19:88
  24. Subjects with prediabetes are at increased risk of future T2DM and cardiovascular disease (CVD) compared to NGT individuals. The OGTT (FPG = 100–125 and 2 h-PG = 140–199 mg/dl) and HbA1c 5.7–6.4% have been use...

    Authors: Saadallah Iskandar, Ayman Migahid, Dalia Kamal, Osama Megahed, Ralph A. DeFronzo, Mahmoud Zirie, Amin Jayyousi, Mahmood Al Jaidah and Muhammad Abdul-Ghani
    Citation: BMC Endocrine Disorders 2019 19:87
  25. The diagnosis of subacute thyroiditis (SAT) is based mainly on the presence of painful thyroid goitre and a significant increase in erythrocyte sedimentation rate (ESR). Proceeding according to these diagnosti...

    Authors: Magdalena Stasiak, Renata Michalak and Andrzej Lewinski
    Citation: BMC Endocrine Disorders 2019 19:86
  26. Older patients with type 2 diabetes mellitus represent a heterogeneous group in terms of metabolic profile. It makes glucose-lowering-therapy (GLT) complex to manage, as it needs to be individualised according...

    Authors: Antoine CHRISTIAENS, Michel P. HERMANS, Benoit BOLAND and Séverine HENRARD
    Citation: BMC Endocrine Disorders 2019 19:85
  27. In patients with diabetes mellitus, the urinary microalbumin-to-urine creatinine ratio (UACR) can not only predict the occurrence of diabetic nephropathy but also can be a risk factor for cardiovascular diseas...

    Authors: Juan Xie, Xiaoqing Wang, Yiyuan Zhang, Hailun Li, Yong Xu and Donghui Zheng
    Citation: BMC Endocrine Disorders 2019 19:84
  28. Thyroid dysfunction is one of the prevalent endocrine disorders. The relationship between lifestyle factors and thyroid dysfunction was not clear and some of the factors seemed paradoxical.

    Authors: Yanling Huang, Liangchun Cai, Yuanyuan Zheng, Jinxing Pan, Liantao Li, Liyao Zong, Wei Lin, Jixing Liang, Huibin Huang, Junping Wen and Gang Chen
    Citation: BMC Endocrine Disorders 2019 19:83
  29. Primary hyperparathyroidism (PHPT), which is mostly caused by a parathyroid adenoma, is fairly common in postmenopausal women but is relatively rare in pregnant women. PHPT-induced pancreatitis during pregnanc...

    Authors: Jun Yang, Meng-jie Dong and Feng Chen
    Citation: BMC Endocrine Disorders 2019 19:82
  30. Elderly patients with type 2 diabetes mellitus (T2DM) experience fractures more frequently than elderly individuals without diabetes. Fractures requiring hospitalization greatly affect quality of life, and alt...

    Authors: Takeshi Horii, Makiko Iwasawa, Yusuke Kabeya, Jyunichi Shimizu and Koichiro Atsuda
    Citation: BMC Endocrine Disorders 2019 19:81
  31. Myasthenia gravis (MG) is the most common disorder of neuromuscular transmission, and it is typified by fluctuating degrees and variable combinations of weakness in the ocular, bulbar, limb, and respiratory mu...

    Authors: Mi-Chu Lin, Ming-Hsien Tsai, Jyh-Gang Leu and Yu-Wei Fang
    Citation: BMC Endocrine Disorders 2019 19:80
  32. Traditionally Type 2 Diabetes Mellitus (T2DM) was associated with older age, but is now being increasingly diagnosed in younger populations due to the increasing prevalence of obesity and inactivity. We aimed ...

    Authors: Laura J. Gray, Emer M. Brady, Olatz Albaina, Charlotte L. Edwardson, Deirdre Harrington, Kamlesh Khunti, Joanne Miksza, João Filipe Raposo, Ellesha Smith, Andriani Vazeou, Itziar Vergara, Susann Weihrauch-Blüher and Melanie J. Davies
    Citation: BMC Endocrine Disorders 2019 19:79
  33. Hypoglycaemia, especially nocturnal, remains the main limiting factor of achieving good glycaemic control in type 1 diabetes.

    Authors: Rikke Mette Agesen, Amra Ciric Alibegovic, Henrik Ullits Andersen, Henning Beck-Nielsen, Peter Gustenhoff, Troels Krarup Hansen, Christoffer Hedetoft, Tonny Jensen, Claus Bogh Juhl, Susanne Søgaard Lerche, Kirsten Nørgaard, Hans-Henrik Parving, Lise Tarnow, Birger Thorsteinsson and Ulrik Pedersen-Bjergaard
    Citation: BMC Endocrine Disorders 2019 19:78
  34. Chronic inflammation has been associated with dysglycemia among people living with HIV (PLHIV). There is however, limited data regarding this phenomenon in sub-Sahara Africa (SSA). Therefore we assessed the le...

    Authors: Lilian Nkinda, Kirtika Patel, Benson Njuguna, Jean Pierre Ngangali, Peter Memiah, George M. Bwire, Mtebe V. Majigo, Mucho Mizinduko, Sonak D. Pastakia and Eligius Lyamuya
    Citation: BMC Endocrine Disorders 2019 19:77
  35. Sarcopenic obesity, central obesity combined with decreased skeletal muscle mass, is identified to be associated with metabolic syndrome and cardiovascular diseases; however, its role in the occurrence of non-...

    Authors: Xiaoyou Su, Jing Xu and Chao Zheng
    Citation: BMC Endocrine Disorders 2019 19:76
  36. To investigate any associations between blood glucose (BG) and lipid levels in patients with different glucose tolerance statuses, including type 2 diabetes (T2DM) and impaired glucose regulation (IGR) cases a...

    Authors: Shujin Wang, Guohong Li, Hong Zuo, Hua Yang, Lei Ma, Jia Feng, Yu Niu, Liming Ma, Songfang Liu, Ting Qi and Xufeng Liu
    Citation: BMC Endocrine Disorders 2019 19:75
  37. Type 2 Diabetes Mellitus (T2DM) has become an endemic disease. A number of interrelated factors increase the risk of the onset of T2DM, however much of the pathogenesis of the disease is associated with lifest...

    Authors: Linda Cloete, Brett G. Mitchell and Darren Morton
    Citation: BMC Endocrine Disorders 2019 19:74
  38. Several studies have indicated that inflammatory markers were associated with the risk of mild cognitive impairment (MCI) in type 2 diabetes (T2D). Serum folate was related to MCI as well as inflammation. Howe...

    Authors: Miaoyan Zheng, Baocheng Chang, Liqiang Tian, Chunyan Shan, Hui Chen, Yuxia Gao, Guowei Huang and Meilin Zhang
    Citation: BMC Endocrine Disorders 2019 19:73
  39. Further knowledge about the pubertal development mode of girls with Turner syndrome (TS) who have undergone hormone replacement therapy (HRT) is beneficial to the proposal of an optimal HRT regimen. This study...

    Authors: Song Guo, Jun Zhang, Yanhong Li, Huamei Ma, Qiuli Chen, Hongshan Chen and Minlian Du
    Citation: BMC Endocrine Disorders 2019 19:72
  40. Metabolic encephalopathy is a rare but potentially devastating complication of diabetic ketoacidosis (DKA). This case highlights the dramatic cognitive decline of a young man due to metabolic encephalopathy co...

    Authors: Maria Tomkins, Richard McCormack, Karen O’Connell, Amar Agha and Áine Merwick
    Citation: BMC Endocrine Disorders 2019 19:71
  41. Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in young women and increases risk of cardiovascular and metabolic disease, and infertility. Women with PCOS share many characteristics com...

    Authors: Laura E. McBreairty, Philip D. Chilibeck, Julianne J. Gordon, Donna R. Chizen and Gordon A. Zello
    Citation: BMC Endocrine Disorders 2019 19:70
  42. To assess the association between cardiorespiratory fitness (CRF) and weight changes in treatment seeking patients with severe obesity who underwent a 1-year intensive lifestyle intervention (ILI) program.

    Authors: Jarle Berge, Øyvind Støren, Jens K. Hertel, Espen Gjevestad, Milada Cvancarova Småstuen and Jøran Hjelmesæth
    Citation: BMC Endocrine Disorders 2019 19:69
  43. Endogenous Cushing’s syndrome, a rare endocrine disorder, characterised by chronic cortisol hypersecretion, results in neuropsychiatric disturbances and in cognitive deficits, which are only partially reversib...

    Authors: Malgorzata Monika Brzozowska, Sacha Kepreotis, Fiona Tsang and Sully Xiomara Fuentes- Patarroyo
    Citation: BMC Endocrine Disorders 2019 19:68
  44. This study aimed to examine the associations between gender and the prevalence of metabolic syndrome (MS) components among Korean adults by age and body mass index (BMI) subgroups.

    Authors: Young-Mo Yang, Byung-Cheul Shin, Chihyoung Son and In-Hyuk Ha
    Citation: BMC Endocrine Disorders 2019 19:67
  45. The aim of the study was to estimate and compare the 8-year cumulative incidence of diabetes mellitus (DM) among Sami and non-Sami inhabitants of rural districts in Northern Norway.

    Authors: Ali Naseribafrouei, Bent Martin Eliassen, Marita Melhus, Johan Svartberg and Ann Ragnhild Broderstad
    Citation: BMC Endocrine Disorders 2019 19:66
  46. The Captopril challenge test (CCT) is an easy-conduct confirmatory test for diagnosing primary aldosteronism (PA). Guidelines show that plasma aldosterone is normally suppressed by captopril (> 30%) in primary...

    Authors: Ke-ying Zhu, Yan Zhang, Wen-jing Zhang, Hong-yun Li, Wen-huan Feng, Da-long Zhu and Ping Li
    Citation: BMC Endocrine Disorders 2019 19:65
  47. For patients with type 2 diabetes (T2D), cardiovascular disease (CVD) is the single most common cause of mortality. In 2008 and 2012, the Federal Drug Administration (FDA) and the European Medicines Agency (EM...

    Authors: Guntram Schernthaner, Heinz Drexel, Evgeny Moshkovich, Birute Zilaitiene, Emil Martinka, Leszek Czupryniak, Tamás Várkonyi, Andrej Janež, Kristine Ducena, Katarina Lalić, Tsvetalina Tankova, Martin Prázný, Lea Smirčić Duvnjak, Olga Sukhareva and Harald Sourij
    Citation: BMC Endocrine Disorders 2019 19:64
  48. Co-existing Cushing’s syndrome and primary aldosteronism caused by bilateral adrenocortical adenomas, secreting cortisol and aldosterone, respectively, have rarely been reported. Precise diagnosis and manageme...

    Authors: Kaiyun Ren, Jia Wei, Qilin Liu, Yuchun Zhu, Nianwei Wu, Ying Tang, Qianrui Li, Qianying Zhang, Yerong Yu, Zhenmei An, Jing Chen and Jianwei Li
    Citation: BMC Endocrine Disorders 2019 19:63
  49. Patients with type 2 diabetes mellitus (T2DM) have accelerated atherosclerosis as a pro thrombotic state that is associated with the platelet activation priming. Platelets, which undergo the continuous mild st...

    Authors: Razie Mahmoodian, Morteza Salimian, Mohsen Hamidpour, Ali Akbar Khadem-Maboudi and Ahmad Gharehbaghian
    Citation: BMC Endocrine Disorders 2019 19:62

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