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  1. Cardiovascular disease (CVD) presents the most serious health problems and contributes to the increased mortality in young women with Turner syndrome. Arterial hypertension in Turner syndrome patients is signi...

    Authors: Ji Yeon Shin, Bo Hyun Kim, Young Keum Kim, Tae Hwa Kim, Eun Heui Kim, Min Jin Lee, Jong Ho Kim, Yun Kyung Jeon, Sang Soo Kim and In Joo Kim

    Citation: BMC Endocrine Disorders 2018 18:27

    Content type: Case report

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  2. Retinol binding protein 4 (RBP4), a protein secreted by adipocytes and bound in plasma to transthyretin (TTR), has been associated with obesity, the early phase of insulin resistance, metabolic syndrome, and t...

    Authors: Karunee Kwanbunjan, Pornpimol Panprathip, Chanchira Phosat, Noppanath Chumpathat, Naruemon Wechjakwen, Somchai Puduang, Ratchada Auyyuenyong, Ina Henkel and Florian J. Schweigert

    Citation: BMC Endocrine Disorders 2018 18:26

    Content type: Research article

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  3. Recent epidemiological studies have suggested inverse associations between vitamin D status and metabolic diseases including type 2 diabetes (T2DM). The aim of this study was to examine whether a higher serum ...

    Authors: Danting Li, Haoche Wei, Hongmei Xue, Jieyi Zhang, Mengxue Chen, Yunhui Gong and Guo Cheng

    Citation: BMC Endocrine Disorders 2018 18:25

    Content type: Research article

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  4. Cushing’s syndrome in humans shares many similarities with its counterpart in dogs in terms of etiology (pituitary versus adrenal causes), clinical signs, and pathophysiologic sequelae. In both species, treatm...

    Authors: Daniel K. Langlois, Michele C. Fritz, William D. Schall, N. Bari Olivier, Rebecca C. Smedley, Paul G. Pearson, Marc B. Bailie and Stephen W. Hunt III

    Citation: BMC Endocrine Disorders 2018 18:24

    Content type: Research article

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  5. 11β-Hydroxylase deficiency (11OHD) is a common form of congenital adrenal hyperplasia that has been shown to result from inactivating CYP11B1 mutations, and pathogenic CYP11B2/CYP11B1 chimeras contribute to a min...

    Authors: Lian Duan, Rufei Shen, Lingyu Song, Yong Liao and Hongting Zheng

    Citation: BMC Endocrine Disorders 2018 18:23

    Content type: Case report

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  6. Adrenocorticotropic hormone (ACTH)-independent Cushing’s syndrome (CS) with bilateral cortisol-secreting adenomas has been rarely reported in the literatures. Precise recognition and management of this disorde...

    Authors: Jia Wei, Sheyu Li, Qilin Liu, Yuchun Zhu, Nianwei Wu, Ying Tang, Qianrui Li, Kaiyun Ren, Qianying Zhang, Yerong Yu, Zhenmei An, Jing Chen and Jianwei Li

    Citation: BMC Endocrine Disorders 2018 18:22

    Content type: Case report

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  7. To our knowledge, no reports are available indicating the effects of synbiotic supplementation on hormonal status, biomarkers of inflammation and oxidative stress in subjects with polycystic ovary syndrome (PC...

    Authors: Khadijeh Nasri, Mehri Jamilian, Elham Rahmani, Fereshteh Bahmani, Maryam Tajabadi-Ebrahimi and Zatollah Asemi

    Citation: BMC Endocrine Disorders 2018 18:21

    Content type: Research article

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  8. Growth hormone deficiency (GHD) is a potential consequence of traumatic brain injury (TBI), including sport-related concussion (SRC). GH stimulation testing is required for definitive diagnosis; however, this ...

    Authors: Kirstie Lithgow, Alex Chin, Chantel T. Debert and Gregory A. Kline

    Citation: BMC Endocrine Disorders 2018 18:20

    Content type: Research article

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  9. Ectopic adrenocorticotropic hormone (ACTH) syndrome (EAS) is caused by tumours releasing ACTH. Ectopic ACTH-producing tumour regression is rarely induced using steroidogenesis inhibitors. We presented a case o...

    Authors: Hideyuki Iwayama, Sho Hirase, Yuka Nomura, Tatsuo Ito, Hiroyuki Morita, Kazuo Otake, Akihisa Okumura and Junko Takagi

    Citation: BMC Endocrine Disorders 2018 18:19

    Content type: Case report

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  10. Here, we report a case of central pontine demyelinization in a type-2 diabetes patient with hyperglycemia after a binge-eating attack in the absence of a relevant hyponatremia.

    Authors: Rainer U. Pliquett, Arno Noll, Richard Ibe, Alexandra Katz, Charlotte Ackmann, Alexandra Schreiber and Matthias Girndt

    Citation: BMC Endocrine Disorders 2018 18:18

    Content type: Case report

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  11. Thyroid nodules are highly prevalent, but a robust, feasible method for malignancy differentiation has not yet been well documented. This study aimed to establish a practical model for thyroid nodule discrimin...

    Authors: Jia Liu, Dongmei Zheng, Qiang Li, Xulei Tang, Zuojie Luo, Zhongshang Yuan, Ling Gao and Jiajun Zhao

    Citation: BMC Endocrine Disorders 2018 18:17

    Content type: Research article

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  12. The evaluation of metabolic syndrome in a society predisposed to the diabetes mellitus epidemic opens a new avenue to understanding this rapidly growing global metabolic problem. Although Saudi Arabia reports ...

    Authors: Khalid Al-Rubeaan, Nahla Bawazeer, Yousuf Al Farsi, Amira M. Youssef, Abdulrahman A. Al-Yahya, Hamid AlQumaidi, Basim M. Al-Malki, Khalid A. Naji, Khalid Al-Shehri and Fahd I. Al Rumaih

    Citation: BMC Endocrine Disorders 2018 18:16

    Content type: Research article

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  13. The aim of this study was to quantify the association of Val109Asp polymorphism of intelectin 1 (ITLN1) gene with the abdominal obesity (AO) in Kyrgyz population.

    Authors: Jainagul Isakova, Elnura Talaibekova, Denis Vinnikov, Nazira Aldasheva, Erkin Mirrakhimov and Almaz Aldashev

    Citation: BMC Endocrine Disorders 2018 18:15

    Content type: Research article

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  14. Impaired insulin activity in women with polycystic ovary syndrome might differ from that seen in type 2 diabetes mellitus without polycystic ovary syndrome. This study was designed to compare the effects of tr...

    Authors: Tao Tao, Peihong Wu, Yuying Wang and Wei Liu

    Citation: BMC Endocrine Disorders 2018 18:14

    Content type: Research article

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  15. Intravenous glucocorticoids (ivGC) have been recommended as a first-line treatment of moderate-to-severe and active thyroid-associated ophthalmopathy (TAO). However, not all patients are responsive to ivGC. Th...

    Authors: Yang Wang, Shuo Zhang, Yidan Zhang, Xingtong Liu, Hao Gu, Sisi Zhong, Yazhuo Huang, Sijie Fang, Jing Sun, Huifang Zhou and Xianqun Fan

    Citation: BMC Endocrine Disorders 2018 18:13

    Content type: Research article

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  16. Continuous glucose monitoring (CGM) enables users to view real-time interstitial glucose readings and provides information on the direction and rate of change of blood glucose levels. Users can also access his...

    Authors: J. Lawton, M. Blackburn, J. Allen, F. Campbell, D. Elleri, L. Leelarathna, D. Rankin, M. Tauschmann, H. Thabit and R. Hovorka

    Citation: BMC Endocrine Disorders 2018 18:12

    Content type: Research article

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  17. Many studies have reported associations between estrogen receptor (ER) gene polymorphisms and postmenopausal osteoporosis (PMOP) risk and bone mineral density (BMD), but the results are controversial. The aim ...

    Authors: Heping Zhu, Jiannong Jiang, Qiang Wang, Jun Zong, Liang Zhang, Tieliang Ma, Youjia Xu and Leiyan Zhang

    Citation: BMC Endocrine Disorders 2018 18:11

    Content type: Research article

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  18. The adverse effects of growth hormone (GH) deficiency (GHD) in adults (AGHD) on metabolism and health-related quality of life (HRQoL) can be improved with GH substitution. This investigation aimed to design a ...

    Authors: Peter H. Kann, Simona Bergmann, Martin Bidlingmaier, Christina Dimopoulou, Birgitte T. Pedersen, Günter K. Stalla, Matthias M. Weber and Stefanie Meckes-Ferber

    Citation: BMC Endocrine Disorders 2018 18:10

    Content type: Research article

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  19. Limited real-world data are currently available on hypoglycemia in diabetes patients. The International Operations Hypoglycemia Assessment Tool (IO HAT) study was designed to estimate hypoglycemia in insulin-t...

    Authors: Rıfat Emral, Tamer Tetiker, Ibrahim Sahin, Ramazan Sari, Ahmet Kaya, İlhan Yetkin, Sefika Uslu Cil and Neslihan Başcıl Tütüncü

    Citation: BMC Endocrine Disorders 2018 18:9

    Content type: Research article

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  20. Ultrasensitive assays to measure pre-pubertal gonadotropins levels could help identify patients with Turner syndrome (TS) in mid-childhood, but studies in this field are scarce. The aim of this study was to an...

    Authors: Stela Carpini, Annelise Barreto Carvalho, Sofia Helena Valente de Lemos-Marini, Gil Guerra-Junior and Andréa Trevas Maciel-Guerra

    Citation: BMC Endocrine Disorders 2018 18:8

    Content type: Research article

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  21. Thyroid eye disease (TED) is a debilitating autoimmune orbital disease that is often a result of Graves’ disease. Dysthyroid optic neuropathy (DON) is a rare but sight-threatening manifestation of TED with the...

    Authors: Shuo Zhang, Yang Wang, Sisi Zhong, Xingtong Liu, Yazhuo Huang, Sijie Fang, Ai Zhuang, Yinwei Li, Jing Sun, Huifang Zhou and Xianqun Fan

    Citation: BMC Endocrine Disorders 2018 18:7

    Content type: Case report

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  22. Although current beta cell replacement therapy is effective in stabilizing glycemic control in highly selected patients with refractory type 1 diabetes, many hurdles are inherent to this and other donor-based ...

    Authors: Klemens Wallner, Rene G. Pedroza, Isaac Awotwe, James M. Piret, Peter A. Senior, A. M. James Shapiro and Christopher McCabe

    Citation: BMC Endocrine Disorders 2018 18:6

    Content type: Research article

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  23. Increased knowledge concerning the differences in the illness perception and self-management among sexes is needed for planning proper support programs for patients with diabetes. The aim of this study was to ...

    Authors: Wimonrut Boonsatean, Anna Carlsson, Irena Dychawy Rosner and Margareta Östman

    Citation: BMC Endocrine Disorders 2018 18:5

    Content type: Research article

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  24. Gestational diabetes insipidus (GDI) is a rare endocrine complication during pregnancy that is associated with vasopressinase overproduction from the placenta. Although increased vasopressinase is associated w...

    Authors: Tatsuya Kondo, Miwa Nakamura, Sayaka Kitano, Junji Kawashima, Takeshi Matsumura, Takashi Ohba, Munekage Yamaguchi, Hidetaka Katabuchi and Eiichi Araki

    Citation: BMC Endocrine Disorders 2018 18:4

    Content type: Case report

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  25. The association between thyroid nodules and adiposity remains controversial. We performed a cross-sectional, community-based study to examine whether thyroid nodules are associated with overweight and obesity,...

    Authors: Bin Song, Zhihua Zuo, Juan Tan, Jianjin Guo, Weiping Teng, Yibing Lu and Chao Liu

    Citation: BMC Endocrine Disorders 2018 18:3

    Content type: Research article

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  26. The approach to acromegalic patients with persistent acromegaly after surgery and inadequate response to first-generation somatostatin receptor ligands (SRLs) should be strictly tailored. Current options inclu...

    Authors: A. Ciresi, S. Radellini, V. Guarnotta and C. Giordano

    Citation: BMC Endocrine Disorders 2018 18:2

    Content type: Case report

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  27. This retrospective study investigated the effect of adding metformin to pharmacologic insulin dosing in type 1 diabetics on insulin therapy 1 year after treatment compared with patients on insulin therapy alone.

    Authors: Selvihan Beysel, Ilknur Ozturk Unsal, Muhammed Kizilgul, Mustafa Caliskan, Bekir Ucan and Erman Cakal

    Citation: BMC Endocrine Disorders 2018 18:1

    Content type: Research article

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  28. Diabetes is one of the most common metabolic disorders, with a high prevalence of patients with poor metabolic control. Worldwide, evidence highlights the importance of developing and implementing educational ...

    Authors: Maria do Rosário Pinto, Pedro Miguel Dinis Santos Parreira, Marta Lima Basto and Lisete dos Santos Mendes Mónico

    Citation: BMC Endocrine Disorders 2017 17:77

    Content type: Research article

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  29. Metabolic syndrome is a cluster of the most dangerous heart attack risk factors such as diabetes and prediabetes, abdominal obesity, high cholesterol and high blood pressure. Hyperuricemia is a condition in wh...

    Authors: Shiferaw Bekele Woyesa, Agete Tadewose Hirigo and Temesgen Bizuayehu Wube

    Citation: BMC Endocrine Disorders 2017 17:76

    Content type: Research article

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  30. We investigated how four aspects of socio-demography influence the effectiveness of an intervention with structured personal diabetes care on long-term outcomes.

    Authors: Andreas Heltberg, Volkert Siersma, John Sahl Andersen, Christina Ellervik, Henrik Brønnum-Hansen, Jakob Kragstrup and Niels de Fine Olivarius

    Citation: BMC Endocrine Disorders 2017 17:75

    Content type: Research article

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  31. We report a rare case of a juxta-adrenal schwannoma that could not be discriminated from an adrenal tumor before surgical resection and was complicated by bilateral hyperaldosteronism. To the best of our knowl...

    Authors: Naru Babaya, Yukako Makutani, Shinsuke Noso, Yoshihisa Hiromine, Hiroyuki Ito, Yasunori Taketomo, Kazuki Ueda, Hokuto Ushijima, Yoshifumi Komoike, Yuto Yamazaki, Hironobu Sasano, Yumiko Kawabata and Hiroshi Ikegami

    Citation: BMC Endocrine Disorders 2017 17:74

    Content type: Case report

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  32. Type 2 diabetes is associated with substantial cardiovascular morbidity and mortality arising from the high prevalence of cardiovascular risk factors such as hypertension, dyslipidaemia, obesity, poor glycaemi...

    Authors: Mercy W. Kimando, Frederick C. F. Otieno, Elijah N. Ogola and Kenn Mutai

    Citation: BMC Endocrine Disorders 2017 17:73

    Content type: Research article

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  33. Individuals with Diabetes Mellitus (DM) are at increased risk for fracture due to the decrease in bone strength and quality. Serum procollagen type I intact N-terminal (P1NP) and serum C-terminal cross-linking...

    Authors: Dyah Purnamasari, Melisa D. Puspitasari, Bambang Setiyohadi, Pringgodigdo Nugroho and Harry Isbagio

    Citation: BMC Endocrine Disorders 2017 17:72

    Content type: Research article

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  34. Vitamin D (VitD) and parathyroid hormone (PTH) play important roles in calcium metabolism and skeletal homeostasis. Estimates of the VitD status in several European countries show large variations between them...

    Authors: Luís Raposo, Sandra Martins, Daniela Ferreira, João Tiago Guimarães and Ana Cristina Santos

    Citation: BMC Endocrine Disorders 2017 17:71

    Content type: Research article

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  35. Type 2 diabetes (T2D) is a progressive disease that often requires a patient to use multiple antihyperglycemic agents to achieve glycemic control with disease progression. Omarigliptin is a once-weekly dipepti...

    Authors: Seung-Hwan Lee, Ira Gantz, Elizabeth Round, Melanie Latham, Edward A. O’Neill, Paulette Ceesay, Shailaja Suryawanshi, Keith D. Kaufman, Samuel S. Engel and Eseng Lai

    Citation: BMC Endocrine Disorders 2017 17:70

    Content type: Research article

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  36. Randomized clinical trials have shown the efficacy and safety of short-acting exenatide in patients with type 2 diabetes mellitus (T2DM). The aim of this observational study was to investigate the effectivenes...

    Authors: You-Cheol Hwang, Ari Kim, Euna Jo, Yeoree Yang, Jae-Hyoung Cho and Byung-Wan Lee

    Citation: BMC Endocrine Disorders 2017 17:68

    Content type: Research article

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  37. Adipose tissue, an endocrine organ of the body, is involved in some obesity-related disease states such as insulin resistance, diabetes mellitus, and atherosclerosis. Vaspin is a novel adipocyte with insulin s...

    Authors: Wei Yang, Yun Li, Tian Tian, Li Wang, Pearl Lee and Qi Hua

    Citation: BMC Endocrine Disorders 2017 17:67

    Content type: Research article

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  38. Self-care is essential for patients with diabetes mellitus. Both clinicians and researchers must be able to assess the quality of that self-care. Available tools have various limitations and none are theoretic...

    Authors: Davide Ausili, Claudio Barbaranelli, Emanuela Rossi, Paola Rebora, Diletta Fabrizi, Chiara Coghi, Michela Luciani, Ercole Vellone, Stefania Di Mauro and Barbara Riegel

    Citation: BMC Endocrine Disorders 2017 17:66

    Content type: Research article

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  39. The metabolic syndrome (MetS) is a combination of unfavourable health factors which includes abdominal obesity, dyslipidaemia, elevated blood pressure and impaired fasting glucose. Earlier studies have reporte...

    Authors: Bruce H. R. Wolffenbuttel, Hanneke J. C. M. Wouters, Sandra N. Slagter, Robert P. van Waateringe, Anneke C. Muller Kobold, Jana V. van Vliet-Ostaptchouk, Thera P. Links and Melanie M. van der Klauw

    Citation: BMC Endocrine Disorders 2017 17:65

    Content type: Research article

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  40. It is well known that dyslipidemia and chronic hyperglycemia increase the onset of diabetes and diabetic complication. The aim of this study is to see the association of trace metals elements and lipid profile...

    Authors: Amare Desalegn Wolide, Belay Zawdie, Tilahun Alemayehu and Samuel Tadesse

    Citation: BMC Endocrine Disorders 2017 17:64

    Content type: Research article

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  41. Insulin treatment has been associated with a paradoxical worsening of diabetes retinopathy since many years in European cohorts. Recently, this issue has been stressed by some studies conducted in other parts ...

    Authors: Ahmadou M. Jingi, Aurel T. Tankeu, Narcisse Assene Ateba and Jean Jacques Noubiap

    Citation: BMC Endocrine Disorders 2017 17:63

    Content type: Debate

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  42. Recent studies have demonstrated that immune factors might have a role in the pathophysiology of insulin resistance and type 2 diabetes mellitus (T2DM). Inappropriate glycemic control in patients with T2DM is ...

    Authors: Muhammed Kizilgul, Ozgur Ozcelik, Selvihan Beysel, Hakan Akinci, Seyfullah Kan, Bekir Ucan, Mahmut Apaydin and Erman Cakal

    Citation: BMC Endocrine Disorders 2017 17:62

    Content type: Research article

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  43. Recent studies show that bile acids are involved in glucose and energy homeostasis through activation of G protein coupled membrane receptor (TGR5) and farnesoid X receptor (FXR). A few researches have explore...

    Authors: Xinfeng Yan, Peicheng Li, Zhaosheng Tang and Bo Feng

    Citation: BMC Endocrine Disorders 2017 17:60

    Content type: Research article

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  44. Slipped capital femoral epiphysis (SCFE) is a common hip disorder characterized by displacement of the capital femoral epiphysis from the metaphysic through the femoral epiphyseal plate. SCFE usually occurs du...

    Authors: Saori Kadowaki, Tomohiro Hori, Hideki Matsumoto, Kaori Kanda, Michio Ozeki, Yu Shirakami, Norio Kawamoto, Hidenori Ohnishi and Toshiyuki Fukao

    Citation: BMC Endocrine Disorders 2017 17:59

    Content type: Case report

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  45. Adrenal crisis (AC) occurs in various clinical conditions but previous epidemiological studies in AC are limited to chronic adrenal insufficiency (AI) and sepsis. The aim of this study was to investigate chara...

    Authors: Masahiro Iwasaku, Maki Shinzawa, Shiro Tanaka, Kimihiko Kimachi and Koji Kawakami

    Citation: BMC Endocrine Disorders 2017 17:58

    Content type: Research article

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  46. Parathyroid water-clear cell hyperplasia (WCCH) and water-clear cell adenoma (WCCA) are rare causes of primary hyperparathyroidism. The frequency of WCCH seems to be less than 1% of all primary hyperplasia.

    Authors: Georgios Boutzios, Helen Sarlanis, Anna Kolindou, Antigoni Velidaki and Theodore Karatzas

    Citation: BMC Endocrine Disorders 2017 17:57

    Content type: Case report

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  47. The increasing prevalence of diabetes is leading to a rise of eye diseases, augmenting the risk of sight-threatening complications. The aim of this study was to evaluate prevalence, awareness and practices reg...

    Authors: Lazaros Konstantinidis, Tania Carron, Eva de Ancos, Léonie Chinet, Isabelle Hagon-Traub, Emilie Zuercher and Isabelle Peytremann-Bridevaux

    Citation: BMC Endocrine Disorders 2017 17:56

    Content type: Research article

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  48. This study aimed to investigate preoperative somatostatin analogs (SSAs) treatment on the surgical outcome in patients with acromegaly.

    Authors: Lian Duan, Huijuan Zhu, Bing Xing and Feng Gu

    Citation: BMC Endocrine Disorders 2017 17:55

    Content type: Research article

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