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  1. The major cause of primary hypothyroidism is autoimmune mediated with progressive and permanent destruction of the thyroid gland resulting in life-long replacement therapy. Treatable and reversible hypothyroid...

    Authors: Huy A Tran
    Citation: BMC Endocrine Disorders 2006 6:3
  2. Although thyroxin therapy clearly is beneficial to children with frank hypothyroidism there is little data on the effects of thyroxin in children with compensated or subclinical hypothyroidism. The objective o...

    Authors: Naghma J Aijaz, Evelyn M Flaherty, Thomas Preston, Stacey Storch Bracken, Andrew H Lane and Thomas A Wilson
    Citation: BMC Endocrine Disorders 2006 6:2
  3. Most patients with growth hormone deficiency (GHD) show high body mass index. Overweight subjects, but GHD patients, were demonstrated to have high left ventricular mass index (LVMi) and abnormal LV geometric ...

    Authors: Cesare de Gregorio, Lorenzo Curtò, Antonino Recupero, Patrizia Grimaldi, Barbara Almoto, Marilena Venturino, Domenico Cento, Maria Carola Narbone, Francesco Trimarchi, Sebastiano Coglitore and Salvatore Cannavò
    Citation: BMC Endocrine Disorders 2006 6:1
  4. The global pattern of varying prevalence of diseases of affluence, such as obesity, cardiovascular disease and diabetes, suggests that some environmental factor specific to agrarian societies could initiate th...

    Authors: Tommy Jönsson, Stefan Olsson, Bo Ahrén, Thorkild C Bøg-Hansen, Anita Dole and Staffan Lindeberg
    Citation: BMC Endocrine Disorders 2005 5:10
  5. The study aims to assess the pattern of thyroid response to combination Interferon-α2β (IFN-α) and Ribavirin (RBV) anti-viral therapy in an Australian hepatitis C cohort. These include the prevalence of thyroi...

    Authors: Huy A Tran, Tracey L Jones and Robert G Batey
    Citation: BMC Endocrine Disorders 2005 5:8
  6. Genetic variants of proteins involved in lipid metabolism may play an important role in determining the susceptibility for complications associated with type II diabetes mellitus (T2DM). Goal of the present st...

    Authors: Manjusha Dixit, Sandeep Bhattacharya and Balraj Mittal
    Citation: BMC Endocrine Disorders 2005 5:7
  7. The prevalence of diabetes mellitus is higher in individuals with Down syndrome (DS) than in the general population; it may be due to the high prevalence of obesity presented by many of them. The aim of this s...

    Authors: Cristina T Fonseca, Daniela M Amaral, Márcia G Ribeiro, Izabel CR Beserra and Marília M Guimarães
    Citation: BMC Endocrine Disorders 2005 5:6
  8. To investigate whether IGF-I promoter polymorphism was associated with birth weight and risk factors for cardiovascular disease (CVD) and type 2 diabetes (T2DM), and whether the birth weight – risk factor relatio...

    Authors: Saskia J te Velde, Elisabeth FC van Rossum, Paul G Voorhoeve, Jos WR Twisk, Henriette A Delemarre van de Waal, Coen DA Stehouwer, Willem van Mechelen, Steven WJ Lamberts and Han CG Kemper
    Citation: BMC Endocrine Disorders 2005 5:5
  9. Both Diabetes and ageing are associated with reduced vascular endothelial function. The exact relationship between the 2 and any improvements from the insulin sensitizer rosiglitazone have not been explored.

    Authors: Jerrold Petrofsky, Scott Lee and Maria Cuneo
    Citation: BMC Endocrine Disorders 2005 5:4
  10. Diagnostic discordance for osteoporosis is the observation that the T-score of an individual patient varies from one key measurement site to another, falling into two different diagnostic categories identified...

    Authors: Alireza Moayyeri, Akbar Soltani, Nasibeh Khaleghnejad Tabari, Mohsen Sadatsafavi, Arash Hossein-neghad and Bagher Larijani
    Citation: BMC Endocrine Disorders 2005 5:3
  11. Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycaemia. Increased oxidative stress and decreased antioxidant levels are the leading cause of diabetes and diabetic complications. So i...

    Authors: Satyanarayana Sreemantula, Eswar K Kilari, Vishnu A Vardhan and Rajasekhar Jaladi
    Citation: BMC Endocrine Disorders 2005 5:2
  12. Biochemical testing for pheochromocytoma by measurement of fractionated plasma metanephrines is limited by false positive rates of up to 18% in people without known genetic predisposition to the disease. The p...

    Authors: Anna M Sawka, Lehana Thabane, Amiram Gafni, Mitchell Levine and William F Young Jr
    Citation: BMC Endocrine Disorders 2005 5:1
  13. Alterations in carbohydrate metabolism are frequently observed in cirrhosis. We conducted this study to define the prevalence of diabetes mellitus (DM) and impaired glucose tolerance (IGT) in Iranian patients ...

    Authors: Seyed M Alavian, Behzad Hajarizadeh, Fariborz Nematizadeh and Bagher Larijani
    Citation: BMC Endocrine Disorders 2004 4:4
  14. Malignant neoplasia of the adrenal cortex is usually associated with very poor prognosis. When adrenocortical neoplasms are diagnosed in the early stages, distinction between carcinoma and adenoma can be very ...

    Authors: Angela S Barbosa, Luciano R Giacaglia, Regina M Martin, Berenice B Mendonca and Chin J Lin
    Citation: BMC Endocrine Disorders 2004 4:3
  15. Fractionated plasma metanephrine measurements are commonly used in biochemical testing in search of pheochromocytoma.

    Authors: Anna M Sawka, Ally PH Prebtani, Lehana Thabane, Amiram Gafni, Mitchell Levine and William F Young Jr
    Citation: BMC Endocrine Disorders 2004 4:2
  16. Many mechanistic steps underlying nutrient-stimulated insulin secretion (NSIS) are poorly understood. The influence of intracellular pH (pHi) on insulin secretion is widely documented, and can be used as an inves...

    Authors: Subhadra C Gunawardana, Jonathan V Rocheleau, W Steven Head and David W Piston
    Citation: BMC Endocrine Disorders 2004 4:1
  17. Newly diagnosed insulin-dependent diabetes mellitus is characterised by a temporary recovery of endogeneous insulin ("remission") after the beginning of medical treatment with subcutaneous insulin injections. ...

    Authors: Thomas Linn, Marion Mann, Markus Mann, Reinhard G Bretzel and Rolf H Boedeker
    Citation: BMC Endocrine Disorders 2003 3:5
  18. The combination of transfusion and chelation therapy has dramatically extended the life expectancy of thalassemic patients. The main objective of this study is to determine the prevalence of prominent thalasse...

    Authors: Alireza Abdollah Shamshirsaz, Mir Reza Bekheirnia, Mohammad Kamgar, Nima Pourzahedgilani, Navid Bouzari, Mohammadreza Habibzadeh, Reza Hashemi, Amirhooshang Abdollah Shamshirsaz, Shahriar Aghakhani, Hooman Homayoun and Bagher Larijani
    Citation: BMC Endocrine Disorders 2003 3:4
  19. Glucagon-like peptide-1 (GLP-1) and its agonists are under assessment in treatment of type 2 diabetes, by virtue of their antidiabetic actions, which include stimulation of insulin secretion, inhibition of glu...

    Authors: Margaret T Behme, John Dupré and Thomas J McDonald
    Citation: BMC Endocrine Disorders 2003 3:3
  20. Tyrosine hydroxylase (TH) activity and its possible participation in the control of insulin secretion were studied in pancreatic islets of adult Wistar rats fed a standard commercial diet (SD) or carbohydrates...

    Authors: María I Borelli, Modesto Rubio, María E García, Luis E Flores and Juan J Gagliardino
    Citation: BMC Endocrine Disorders 2003 3:2
  21. The incidence and risk factors for diabetic ketoacidosis (diabetic ketoacidosis) and hyperglycemic hyperosmolar syndrome (hyperglycemic hyperosmolar syndrome, previously called non-ketotic hyperosmolar coma) h...

    Authors: Kevin C Abbott, Victor J Bernet, Lawrence Y Agodoa and Christina M Yuan
    Citation: BMC Endocrine Disorders 2003 3:1
  22. Autonomous thyroid nodules can be treated by a variety of methods. We assessed the efficacy of percutaneous ethanol injection in treating autonomous thyroid nodules.

    Authors: Bagher Larijani, Mohammad Pajouhi, Hossein Ghanaati, Mohammad-Hassan Bastanhagh, Fereshteh Abbasvandi, Kazem Firooznia, Mahmood Shirzad, Mohammad-Reza Amini, Maryam Sarai, Nasreen Abbasvandi and Reza Baradar-Jalili
    Citation: BMC Endocrine Disorders 2002 2:3
  23. It has become increasingly clear that β-cell failure plays a critical role in the pathogenesis of type 2 diabetes. Free-radical mediated β-cell damage has been intensively studied in type 1 diabetes, but not i...

    Authors: Björn Tyrberg, Kamen A Anachkov, Sergio A Dib, Jessica Wang-Rodriguez, Kun-Ho Yoon and Fred Levine
    Citation: BMC Endocrine Disorders 2002 2:2

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