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  1. Although chronic adrenocorticotropic hormone (ACTH) and androgen hyperstimulation are assumed to be involved in the pathogenesis of adrenal myelolipomas associated with poor-compliance patients with congenital...

    Authors: Madson Q Almeida, Laura C Kaupert, Luciana P Brito, Antonio M Lerario, Beatriz M P Mariani, Marta Ribeiro, Osmar Monte, Francisco T Denes, Berenice B Mendonca and Tânia ASS Bachega
    Citation: BMC Endocrine Disorders 2014 14:42
  2. Previously considered as a disease of the affluent, west or urban people and not of public health importance, diabetes mellitus is increasingly becoming a significant cause of morbidity and mortality in sub-Sahar...

    Authors: Kelias Phiri Msyamboza, Chimwemwe J Mvula and Damson Kathyola
    Citation: BMC Endocrine Disorders 2014 14:41
  3. Increased morbidity and mortality associated with conventional glucocorticoid replacement therapy for primary adrenal insufficiency (primary AI; estimated prevalence 93–140/million), secondary AI (estimated pr...

    Authors: Bertil Ekman, David Fitts, Claudio Marelli, Robert D Murray, Marcus Quinkler and Pierre MJ Zelissen
    Citation: BMC Endocrine Disorders 2014 14:40
  4. Few studies have examined young adults with type 1 diabetes use of health services and the development of vascular complications. As part of the Youth Outreach for Diabetes (YOuR-Diabetes) project, this study ...

    Authors: Steven James, Lin Perry, Robyn Gallagher, Julia Lowe, Janet Dunbabin, Patrick McElduff, Shamasunder Acharya and Katharine Steinbeck
    Citation: BMC Endocrine Disorders 2014 14:39
  5. Central precocious puberty (CPP) and phenylketonuria (PKU) are two rare conditions, the latter being the rarer. To date, only one case featuring both these conditions has been reported, and hyperphenylalaninem...

    Authors: Laura Lucaccioni, Bernd C Schwahn, Malcolm Donaldson and Claudio Giacomozzi
    Citation: BMC Endocrine Disorders 2014 14:38
  6. Canagliflozin is a sodium glucose co-transporter 2 inhibitor developed for the treatment of patients with type 2 diabetes mellitus (T2DM). The efficacy and safety of canagliflozin were evaluated in patients wi...

    Authors: Alan Sinclair, Bruce Bode, Stewart Harris, Ujjwala Vijapurkar, Cristiana Mayer, Albert Fung, Wayne Shaw, Keith Usiskin, Mehul Desai and Gary Meininger
    Citation: BMC Endocrine Disorders 2014 14:37
  7. Insulin aspart (IAsp) and its biphasic preparations BIAsp50 and BIAsp70 (containing 50% and 70% IAsp, respectively) have distinct glucose-lowering properties as compared to human insulin (HI). We investigated ...

    Authors: Zhulin Ma, Jens Sandahl Christiansen, Torben Laursen, Chunsen Wu, Torsten Lauritzen, Tina Parkner and Jan Frystyk
    Citation: BMC Endocrine Disorders 2014 14:35
  8. Osmotic demyelination syndrome (ODS) may be observed as a result of a rapid change in serum osmolarity, such as that induced by an overly rapid correction of serum sodium levels in hyponatraemic patients.

    Authors: Giovanni Corona, Luigi Simonetti, Corinna Giuliani, Alessandra Sforza and Alessandro Peri
    Citation: BMC Endocrine Disorders 2014 14:34
  9. Increased risk of osteoporosis and its clinical significance in patients with diabetes is controversial. We analyze osteoporosis prevalence and determinants of bone mineral density (BMD) in patients with type ...

    Authors: Gudrun Leidig-Bruckner, Sonja Grobholz, Thomas Bruckner, Christa Scheidt-Nave, Peter Nawroth and Jochen G Schneider
    Citation: BMC Endocrine Disorders 2014 14:33
  10. Seminomas have been rarely associated with malignant hypercalcemia. The responsible mechanism of hypercalcemia in this setting has been described to be secondary to 1,25-dihydroxyvitamin D secretion. The relat...

    Authors: René Rodríguez-Gutiérrez, Maria Azucena Zapata-Rivera, Dania Lizeth Quintanilla-Flores, Carlos Rodrigo Camara-Lemarroy, Fernando Javier Lavalle-Gonzalez, José Gerardo González-González and Jesús Zacarías Villarreal-Pérez
    Citation: BMC Endocrine Disorders 2014 14:32
  11. Diabetes education and self-care remains the cornerstone of diabetes management. There are many structured diabetes modules available in the United Kingdom, Europe and United States of America. Contrastingly, ...

    Authors: Badariah Ahmad, Amutha Ramadas, Quek Kia Fatt and Anuar Zaini Md Zain
    Citation: BMC Endocrine Disorders 2014 14:31
  12. Continuous intraperitoneal insulin infusion (CIPII) with an implantable pump is a treatment option for patients with type 1 diabetes mellitus (T1DM). Aim of the present study was to describe the long-term cour...

    Authors: Peter R van Dijk, Susan JJ Logtenberg, Klaas H Groenier, Rijk OB Gans, Nanne Kleefstra and Henk JG Bilo
    Citation: BMC Endocrine Disorders 2014 14:30
  13. Aldosterone synthase (CYP11B2) deficiency is a rare autosomal recessive disorder, usually presenting with severe salt-wasting in infancy or stress-induced hyperkalaemia and postural hypotension in adulthood. Neon...

    Authors: Elaine Hui, Matthew CW Yeung, Pik To Cheung, Elaine Kwan, Louis Low, Kathryn CB Tan, Karen SL Lam and Angel OK Chan
    Citation: BMC Endocrine Disorders 2014 14:29
  14. The effects of brain natriuretic peptide (BNP) on the risk of cardiovascular disease and atherosclerosis have been studied. However, little information is available regarding peripheral arterial disease (PAD),...

    Authors: Qi-hui Jin, Wan-lan Ye, Huai-hong Chen, Xiao-jun He, Tian-lang Li, Qiang Liu, Liang Zhong, Lei Xu and Chun-mao Han
    Citation: BMC Endocrine Disorders 2014 14:27
  15. Hand-foot syndrome (HFS), also known as palmar-plantar Erythrodysesthesia (PPE), acral erythema or Burgdorf reaction, is a dermatologic toxic reaction to certain chemotherapies, including sorafenib. A high inc...

    Authors: Carlos Velandia-Carrillo, Edwin Wandurraga-Sánchez and Diego Gómez-Abreo
    Citation: BMC Endocrine Disorders 2014 14:26
  16. To study hormonal changes associated with severe hyperglycemia in critically ill children and the relationship with prognosis and length of stay in intensive care.

    Authors: Yolanda Ballestero, Jesús López-Herce, Rafael González, Maria José Solana, Jimena del Castillo, Javier Urbano, Marta Botran, Ana García, Nieves López and Jose María Bellón
    Citation: BMC Endocrine Disorders 2014 14:25
  17. The editors of BMC Endocrine Disorders would like to thank all our reviewers who have contributed to the journal in Volume 13 (2013).

    Authors: Tim Shipley
    Citation: BMC Endocrine Disorders 2014 14:15
  18. The purpose of this study was to evaluate the association between blood manganese levels and the prevalence of chronic diseases in the Korean population.

    Authors: Eun Sil Koh, Sung Jun Kim, Hye Eun Yoon, Jong Hee Chung, Sungjin Chung, Cheol Whee Park, Yoon Sik Chang and Seok Joon Shin
    Citation: BMC Endocrine Disorders 2014 14:24
  19. The aim of the present study is to examine the clinical indices related to cardiovascular risk management of Greek patients with type 2 diabetes, before and after the major economic crisis that emerged in the ...

    Authors: Stavros Liatis, Stavroula Papaoikonomou, Asimina Ganotopoulou, Athanasia Papazafiropoulou, Constantinos Dinos, Marios Michail, Apostolos Xilomenos, Andreas Melidonis and Stavros Pappas
    Citation: BMC Endocrine Disorders 2014 14:23
  20. Due to ongoing rise in need for care for people with chronic diseases and lagging increase in number of care providers, alternative forms of care provision and self-management support are needed. Empowering pa...

    Authors: Yvonne Roelofsen, Steven H Hendriks, Floor Sieverink, Michael van Vugt, Kornelis JJ van Hateren, Frank J Snoek, Maartje de Wit, Rijk OB Gans, Klaas H Groenier, Julia EWC van Gemert-Pijnen, Nanne Kleefstra and Henk JG Bilo
    Citation: BMC Endocrine Disorders 2014 14:22
  21. Many type 2 diabetes mellitus patients face difficulties self-managing their illness, which can lead to high levels of diabetes-related distress. Diabetes distress may be decreased by peer support, as peers un...

    Authors: Lianne de Vries, Amber AWA van der Heijden, Esther van 't Riet, Caroline A Baan, Piet J Kostense, Mieke Rijken, Guy EHM Rutten and Giel Nijpels
    Citation: BMC Endocrine Disorders 2014 14:21
  22. Diabetic retinopathy (DR) is one of the leading causes for complete loss of vision among working-aged adults around the world. The present study aims to evaluate the rate of DR and its risk factors among the a...

    Authors: Prasad Katulanda, Yasindu C Waniganayake, Priyanga Ranasinghe, WM Udai Akalanka Wijetunga, Mahesh Jayaweera, Nishantha P Wijesinghe, Rezvi Sheriff and David R Matthews
    Citation: BMC Endocrine Disorders 2014 14:20
  23. Hyperglycemia induces chromatin remodeling with consequences on differential gene expression in mouse hepatocytes, similar to what occurs during aging. The liver is the central organ for the regulation of gluc...

    Authors: Flávia G Ghiraldini, André B Silveira, Dirk A Kleinjan, Nick Gilbert and Maria Luiza S Mello
    Citation: BMC Endocrine Disorders 2014 14:19
  24. Hyperhomocysteinemia is a well-known cardiovascular risk factor and its elevation is established in overt hypothyroidism. Since some authors suggest that chronic autoimmune thyroiditis per se may be considered...

    Authors: Maciej Owecki, Jolanta Dorszewska, Nadia Sawicka-Gutaj, Anna Oczkowska, Michał K Owecki, Michał Michalak, Jakub Fischbach, Wojciech Kozubski and Marek Ruchała
    Citation: BMC Endocrine Disorders 2014 14:18
  25. To compare the safety and efficacy of saxagliptin 2.5 mg twice daily (BID) versus placebo add-on therapy to metformin immediate release (IR) in patients with type 2 diabetes and inadequate glycemic control wit...

    Authors: Judith L White, Patricia Buchanan, Jia Li and Robert Frederich
    Citation: BMC Endocrine Disorders 2014 14:17
  26. Aromatase deficiency is a rare, autosomal recessive disorder of which there are approximately twenty four case reports. The aromatase enzyme is crucial in the biosynthesis of oestrogens from androgens. The phe...

    Authors: Lucia Gagliardi, Hamish S Scott, Jinghua Feng and David J Torpy
    Citation: BMC Endocrine Disorders 2014 14:16
  27. The possible association between metabolic syndrome (MS) and bone mineral density (BMD) has been highlighted recently. However, the exact effects of MS on calcaneal quantitative ultrasound (QUS) parameters rem...

    Authors: Min Sun, Mengdie Cao, Qi Fu, Zhenxin Zhu, Chuchen Meng, Jia Mao, Yun Shi, Yu Duan, Wei Tang, Xiaoping Huang, Wei He and Tao Yang
    Citation: BMC Endocrine Disorders 2014 14:14
  28. Emerging epidemiological evidence suggest an association between metabolic syndrome and fractures. However, whether metabolic syndrome is an independent risk or protective factor of fractures remains controver...

    Authors: Kan Sun, Jianmin Liu, Nan Lu, Hanxiao Sun and Guang Ning
    Citation: BMC Endocrine Disorders 2014 14:13
  29. Steroid cell tumors of ovary account for less than 0.1% of all ovarian tumors and these tumours may present at any age in association with interesting presentations related to hormonal activities. The subtype,...

    Authors: Menghua Yuan, Mingcai Qiu and Mei Zhu
    Citation: BMC Endocrine Disorders 2014 14:12
  30. Diabetic cardiomyopathy is associated with a number of functional and structural pathological changes such as left ventricular dysfunction, cardiac remodeling, and apoptosis. The primary cause of diabetic card...

    Authors: Romana Bohuslavova, Frantisek Kolar, David Sedmera, Lada Skvorova, Frantisek Papousek, Jan Neckar and Gabriela Pavlinkova
    Citation: BMC Endocrine Disorders 2014 14:11
  31. Thyroid dysfunction is a common complication of chronic hepatitis C (CHC) and its therapy. Takotsubo cardiomyopathy (TCM) is a multifactorial, stress related cardiomyopathy, rarely reported in association with th...

    Authors: Carmen Sorina Martin, Luminita Nicoleta Ionescu, Carmen Gabriela Barbu, Anca Elena Sirbu, Ioana Maria Lambrescu, Ioana Smarandita Lacau, Doina Ruxandra Dimulescu and Simona Vasilica Fica
    Citation: BMC Endocrine Disorders 2014 14:10
  32. Not all obese subjects have an adverse metabolic profile predisposing them to developing type 2 diabetes or cardiovascular disease. The BioSHaRE-EU Healthy Obese Project aims to gain insights into the conseque...

    Authors: Jana V van Vliet-Ostaptchouk, Marja-Liisa Nuotio, Sandra N Slagter, Dany Doiron, Krista Fischer, Luisa Foco, Amadou Gaye, Martin Gögele, Margit Heier, Tero Hiekkalinna, Anni Joensuu, Christopher Newby, Chao Pang, Eemil Partinen, Eva Reischl, Christine Schwienbacher…
    Citation: BMC Endocrine Disorders 2014 14:9
  33. The rate of bone turnover is closely related to osteoporosis risk. We investigated the correlation between bone turnover markers and BMD at various skeletal sites in healthy native Chinese women, and to study ...

    Authors: Xi-Yu Wu, Hong-Li Li, Hui Xie, Xiang-Hang Luo, Yi-Qun Peng, Ling-Qing Yuan, Zhi-Feng Sheng, Ru-Chun Dai, Xian-Ping Wu and Er-Yuan Liao
    Citation: BMC Endocrine Disorders 2014 14:8
  34. Adipose tissue (AT) contributes to metabolic dysfunction through imbalanced production of adipokines, including cytokines. Visceral AT in particular is associated with metabolic disorders, indicating a specifi...

    Authors: Henrik Svensson, Birgitta Odén, Staffan Edén and Malin Lönn
    Citation: BMC Endocrine Disorders 2014 14:7
  35. Thyroid metastases are clinically rare, and usually occur in patients with a history of prior malignancy and when there are metastases elsewhere. Metastases of pancreatic carcinoma to the thyroid are extremely...

    Authors: Alessandro P Delitala, Gianpaolo Vidili, Alessandra Manca, Upinder Dial, Giuseppe Delitala and Giuseppe Fanciulli
    Citation: BMC Endocrine Disorders 2014 14:6
  36. A diagnosis of subacute thyroiditis is readily considered when patients present with a particular set of typical clinical characteristics. Subacute thyroiditis sometimes presents as a solitary cold nodule; how...

    Authors: Lian-Xi Li, Xing Wu, Bing Hu, Hui-Zhen Zhang and Han-Kui Lu
    Citation: BMC Endocrine Disorders 2014 14:4
  37. Trisomy 9p is an uncommon anomaly characterised by mental retardation, head and facial abnormalities, congenital heart defects, kidney abnormalities, and skeletal malformations. Affected children may also show...

    Authors: Stefano Stagi, Elisabetta Lapi, Salvatore Seminara, Silvia Guarducci, Marilena Pantaleo, Sabrina Giglio, Francesco Chiarelli and Maurizio de Martino
    Citation: BMC Endocrine Disorders 2014 14:3
  38. Several studies have shown the association of solute carrier family 30 (zinc transporter) member 8 (SLC30A8) rs13266634 with type 2 diabetes (T2D). However, the association of alternative variants and haplotyp...

    Authors: Sameer D Salem, Riyadh Saif-Ali, Ikram S Ismail, Zaid Al-Hamodi and Sekaran Muniandy
    Citation: BMC Endocrine Disorders 2014 14:2
  39. Studies have shown that group Therapeutic Patient Education (TPE) may empower patients with type 2 diabetes to better manage their disease. The mechanism of these interventions is not fully understood. A reduc...

    Authors: Liora Valinsky, Moshe Mishali, Ronit Endevelt, Rachel Preiss, Keren Dopelt and Anthony D Heymann
    Citation: BMC Endocrine Disorders 2013 13:61
  40. Existing inconclusive data on the relationship between vitamin D status and human glucose homeostasis suggests that other factors, such as adiposity, might influence this relationship. The present study aimed ...

    Authors: Hataikarn Nimitphong, La-or Chailurkit, Suwannee Chanprasertyothin, Piyamitr Sritara and Boonsong Ongphiphadhanakul
    Citation: BMC Endocrine Disorders 2013 13:60
  41. One possible barrier to effective diabetes self-management is hypoglycaemia associated with diabetes medication. The current study was conducted to characterize hypoglycaemic events among UK patients with type...

    Authors: Beth D Mitchell, Jeffrey Vietri, Anthony Zagar, Bradley Curtis and Matthew Reaney
    Citation: BMC Endocrine Disorders 2013 13:59
  42. The discovery of sodium-glucose co-transporter 2 (SGLT2) inhibitors, with a novel mechanism independent of insulin secretion or sensitization, bring about a new therapeutic approach to the management of type 2...

    Authors: Asres Berhan and Alex Barker
    Citation: BMC Endocrine Disorders 2013 13:58
  43. Lifestyle intervention in type 2 diabetes mellitus (T2DM) is effective but needs a special local setting and is costly. Therefore, in a randomized-controlled trial we tested the hypothesis that the autonomous ...

    Authors: Kerstin Kempf and Stephan Martin
    Citation: BMC Endocrine Disorders 2013 13:57
  44. The complex process of development of the pituitary gland is regulated by a number of signalling molecules and transcription factors. Mutations in these factors have been identified in rare cases of congenital...

    Authors: Jana Breitfeld, Susanne Martens, Jürgen Klammt, Marina Schlicke, Roland Pfäffle, Kerstin Krause, Kerstin Weidle, Dorit Schleinitz, Michael Stumvoll, Dagmar Führer, Peter Kovacs and Anke Tönjes
    Citation: BMC Endocrine Disorders 2013 13:56
  45. Around 10 per cent of catecholamine-secreting tumours can be found outside the adrenal medulla (paraganglioma). We report a case of a functional sporadic paraganglioma that was localized lateral to the prostat...

    Authors: Jesper Kers, Zaheeb A Choudhry, Ton A Roeleveld and Alexander PJ Houdijk
    Citation: BMC Endocrine Disorders 2013 13:55
  46. Allograft inflammatory factor 1 (AIF-1) is a putative obesity gene. Our aim was to examine the expression of AIF-1 in human white adipose tissue (WAT) in relation to obesity and metabolic phenotypes in women.

    Authors: Silvia Lorente-Cebrián, Pauline Decaunes, Elisabeth Dungner, Anne Bouloumié, Peter Arner and Ingrid Dahlman
    Citation: BMC Endocrine Disorders 2013 13:54

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