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  1. To examine the effects of physical activity on the development and progression of microvascular complications in patients with type 1 diabetes.

    Authors: Caroline BT Makura, Krishnarajah Nirantharakumar, Alan J Girling, Ponnusamy Saravanan and Parth Narendran
    Citation: BMC Endocrine Disorders 2013 13:37
  2. Our aim was to assess the associations between vitamin D (vitD) status, metabolic profile and polymorphisms in genes involved in the transport (Group-Component: GC) and the hydroxylation (NAD synthetase 1: NADSYN...

    Authors: Lydia Foucan, Fritz-Line Vélayoudom-Céphise, Laurent Larifla, Christophe Armand, Jacqueline Deloumeaux, Cedric Fagour, Jean Plumasseau, Marie-Line Portlis, Longjian Liu, Fabrice Bonnet and Jacques Ducros
    Citation: BMC Endocrine Disorders 2013 13:36
  3. Ghrelin and peptide YY (PYY) are appetite regulating hormones secreted from the gastrointestinal tract (gut). Aside from their known effect on energy homeostasis, accumulating data indicates that these gut hor...

    Authors: Peyvand Amini, Farrell Cahill, Danny Wadden, Yunqi Ji, Pardis Pedram, Sangeetha Vidyasankar, Yanqing Yi, Wayne Gulliver, Gary Paterno, Hongwei Zhang, Alecia Rideout and Guang Sun
    Citation: BMC Endocrine Disorders 2013 13:35
  4. Alterations in the naive T cell subpopulations have been demonstrated in patients with T cell mediated autoimmune disorders, reminiscent of immunological changes found in the elderly during immunosenescence, i...

    Authors: Martina Prelog, Jörn Schönlaub, Reinhard Würzner, Christian Koppelstaetter, Giovanni Almanzar, Andrea Brunner, Martin Gasser, Rupert Prommegger, Gabriele Häusler, Klaus Kapelari and Wolfgang Högler
    Citation: BMC Endocrine Disorders 2013 13:34
  5. Insufficient vitamin D status and increased renin-angiotensin system (RAS) activity have been associated with renal-vascular disease and nephropathy in diabetes. Accumulating evidence indicates that vitamin D ...

    Authors: Jenifer M Brown, Kristina Secinaro, Jonathan S Williams and Anand Vaidya
    Citation: BMC Endocrine Disorders 2013 13:33
  6. The interaction of advanced glycation end products (AGEs) and its receptor (RAGE) has played an important role in the pathogenesis of diabetes and its complications. A soluble form of RAGE (sRAGE) has been rep...

    Authors: Tarek MK Motawi, Mohamed A Abou-Seif, Ahmed MA Bader and Mohamed O Mahmoud
    Citation: BMC Endocrine Disorders 2013 13:32
  7. Sub-clinical hypothyroid dysfunction, a relatively understudied disorder in the Kingdom of Saudi Arabia (KSA), has significant clinical implications if not properly monitored. Also from KSA, more than 50% of t...

    Authors: Naji J Aljohani, Nasser M Al-Daghri, Omar S Al-Attas, Majed S Alokail, Khalid M Alkhrafy, Abdulaziz Al-Othman, Sobhy Yakout, Abdulaziz F Alkabba, Ahmed S Al-Ghamdi, Mussa Almalki, Badurudeen Mahmood Buhary and Shaun Sabico
    Citation: BMC Endocrine Disorders 2013 13:31
  8. To examine the association of anthropometry indices with gout and to compare the performance of indices to predict gout in Taiwanese men.

    Authors: Wen-Yu Lin, Chia-Chi Lung, Ting-Sung Liu, Zhi-Hong Jian, Pei-Chieh Ko, Jing-Yang Huang, Chien-Chang Ho, Shih-Chang Chen, Yi-Chen Chiang and Yung-Po Liaw
    Citation: BMC Endocrine Disorders 2013 13:30
  9. Sorafenib can be considered as the effective option of treatment in patients with metastatic radioiodine refractory differentiated thyroid cancers. The cutaneous manifestations of Sorafenib include rash, desqu...

    Authors: Syed Zubair Hussain, Ali Asghar, Mubasher Ikram and Najmul Islam
    Citation: BMC Endocrine Disorders 2013 13:29
  10. Being an intermediate stage in the development of diabetes, pre-diabetics were estimated as high as 14% to 63% in China and one to three quarters of them will develop into diabetes within 10 years. It is well ...

    Authors: Rui Feng, Kaichun Li, Jing Cheng, Shaoyu Xie, Jing Chai, Pingfu Wei and Debin Wang
    Citation: BMC Endocrine Disorders 2013 13:28
  11. Hypothyroidism, commonly induced in preparation for radioiodine treatment of differentiated thyroid cancer, is a text-book cause for hyponatremia. Nausea, stress, and increased fluid intake associated with the...

    Authors: Muhammad M Hammami, Fahad Almogbel, Sumaya Hammami, Jaber Faifi, Awad Alqahtani and Walid Hashem
    Citation: BMC Endocrine Disorders 2013 13:27
  12. The abnormality of interleukin-21 (IL-21)-IL-21-receptor (IL-21R) system has been found in many autoimmune diseases including autoimmune thyroid diseases (AITDs). In this study, we investigated whether polymor...

    Authors: Jian Zhang, Wan Xia Xiao, Yuan Feng Zhu, Fatuma Said Muhali, Ling Xiao, Wen Juan Jiang, Xiao Hong Shi, Lian Hua Zhou and Jin An Zhang
    Citation: BMC Endocrine Disorders 2013 13:26
  13. Diabetes distress is a general term that refers to the emotional burdens, anxieties, frustrations, stressors and worries that stem from managing a severe, complex condition like Type 1 diabetes. To date there ...

    Authors: Myles Balfe, Frank Doyle, Diarmuid Smith, Seamus Sreenan, Ruairi Brugha, David Hevey and Ronan Conroy
    Citation: BMC Endocrine Disorders 2013 13:25
  14. In randomized controlled trials (RCTs), colesevelam HCI, added to other anti-diabetic therapy, reduced hemoglobin A1C by approximately 0.3% to 0.4% over 16- to 26-weeks compared with an increase of approximate...

    Authors: Richard A Hansen, Joel F Farley, Matthew L Maciejewski, Xin Ye, Chunlin Qian and Ben Powers
    Citation: BMC Endocrine Disorders 2013 13:24
  15. Infection is the most common precipitating factor and cause of death in patients with hyperglycemic crises. Treating infection-precipitated hyperglycemic crises includes using empiric antibiotics early; correc...

    Authors: Chien-Cheng Huang, Willy Chou, Hung-Jung Lin, Shih-Chung Chen, Shu-Chun Kuo, Wei-Lung Chen, Jiann-Hwa Chen, Hsien-Yi Wang and How-Ran Guo
    Citation: BMC Endocrine Disorders 2013 13:23
  16. Down syndrome (DS) has been described as one of the main contributors for low bone mineral density (BMD). Physical activity (PA) is a key factor in skeletal health and thus, PA levels might be associated to th...

    Authors: Ángel Matute-Llorente, Alejandro González-Agüero, Alba Gómez-Cabello, Germán Vicente-Rodríguez and José Antonio Casajús
    Citation: BMC Endocrine Disorders 2013 13:22
  17. Chronic insulin resistance, exacerbated in the course of pregnancy, is an important pathophysiologic mechanism of gestational diabetes mellitus (GDM). We hypothesise that the degree of insulin resistance, asse...

    Authors: Alina Sokup, Barbara Ruszkowska-Ciastek, Krzysztof Góralczyk, Małgorzata Walentowicz, Marek Szymański and Danuta Rość
    Citation: BMC Endocrine Disorders 2013 13:21
  18. Type 2 diabetes is a common and costly illness, associated with significant morbidity and mortality. Despite this, there is relatively little information on the ‘real-world’ medication utilization patterns for...

    Authors: Manjiri Pawaskar, Machaon Bonafede, Barbara Johnson, Robert Fowler, Gregory Lenhart and Byron Hoogwerf
    Citation: BMC Endocrine Disorders 2013 13:20
  19. Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a common cause of hyponatremia in hospitalized patients and is often described in patients with small-cell carcinoma of the lung. In this rep...

    Authors: Chong-Gui Zhu, Qiu-Zi Zhang, Mei Zhu, Qiong-Li Zhai, Xiao-Yu Liang, Zong-Hong Shao, Emily C Ver Hoeve and Hui-Qi Qu
    Citation: BMC Endocrine Disorders 2013 13:19
  20. The aim was to study the glycaemic control of type 2 diabetic patients, and to identify factors associated with unacceptable glycaemic control (defined as HbA1c >8.0%).

    Authors: Joanne Hui Min Quah, Yan Ping Liu, Nan Luo, Choon How How and Ee Guan Tay
    Citation: BMC Endocrine Disorders 2013 13:18
  21. Autoimmune thyroid diseases including Graves’ disease and Hashimoto’s thyroiditis are caused by immune response to self-thyroid antigens. The rare situation of hyperthyroidism with Graves’ disease in twins has...

    Authors: Christoph A Rüst, Beat Knechtle and Thomas Rosemann
    Citation: BMC Endocrine Disorders 2013 13:17
  22. Marine-Lenhart syndrome is defined as the co-occurrence of Graves’ disease and functional nodules. The vast majority of autonomous adenomas are benign, whereas functional thyroid carcinomas are considered to b...

    Authors: Thomas Scherer, Evelyne Wohlschlaeger-Krenn, Michaela Bayerle-Eder, Christian Passler, Angelika Reiner-Concin, Michael Krebs and Alois Gessl
    Citation: BMC Endocrine Disorders 2013 13:16
  23. This study compares annual ambulatory care expenditures per patient with type 2 diabetes mellitus (T2DM) in France according to treatment phase and renal function status.

    Authors: Florent Guelfucci, Emilie Clay, Samuel Aballéa, Régis Lassalle, Nicholas Moore and Mondher Toumi
    Citation: BMC Endocrine Disorders 2013 13:15
  24. Hypovitaminosis D is a common condition among elderly individuals in temperate-climate countries, with a clear seasonal variation on 25 hydroxyvitamin D [(25(OH)D] levels, increasing after summer and decreasin...

    Authors: Sergio Setsuo Maeda, Gabriela Luporini Saraiva, Ilda Sizue Kunii, Lilian Fukusima Hayashi, Maysa Seabra Cendoroglo, Luiz Roberto Ramos and Marise Lazaretti-Castro
    Citation: BMC Endocrine Disorders 2013 13:14
  25. HIV patients on HAART are prone to metabolic abnormalities, including insulin resistance, lipodystrophy and diabetes. This study purports to investigate the relationship of ethnicity and CD4+ T cell count atta...

    Authors: Ranjita Misra, Prakash Chandra, Steven E Riechman, Dustin M Long, Shivani Shinde, Henry J Pownall, Ivonne Coraza, Dorothy E Lewis, Rajagopal V Sekhar and Ashok Balasubramanyam
    Citation: BMC Endocrine Disorders 2013 13:13
  26. To investigate potential associations of serum prolactin concentration (PRL) with metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM), previously observed in small and selected study samples, in a la...

    Authors: Lisa Balbach, Henri Wallaschofski, Henry Völzke, Matthias Nauck, Marcus Dörr and Robin Haring
    Citation: BMC Endocrine Disorders 2013 13:12
  27. Osteocalcin (OC) is a bone-specific protein produced primarily by osteoblasts during bone formation. Besides its role in bone formation, osteocalcin may play a role in the regulation of energy metabolism and m...

    Authors: Anke Hannemann, Nele Friedrich, Christin Spielhagen, Rainer Rettig, Till Ittermann, Matthias Nauck and Henri Wallaschofski
    Citation: BMC Endocrine Disorders 2013 13:11
  28. The editors of BMC Endocrine Disorders would like to thank all our reviewers who have contributed to the journal in Volume 12 (2012).

    Authors: Tim Shipley
    Citation: BMC Endocrine Disorders 2013 13:6
  29. Diabetic patients with positive glutamic acid decarboxylase antibody (GAD-Ab) could be classified as autoimmune diabetes, which is discriminated into acute-onset classical type 1 diabetes (T1DM) and latent aut...

    Authors: Xia Li, Gan Huang, Jian Lin, Lin Yang and Zhiguang Zhou
    Citation: BMC Endocrine Disorders 2013 13:10
  30. The glycated haemoglobin A1c (HbA1c) level may be used for screening for type 2 diabetes and prediabetes instead of a more burdensome oral glucose tolerance test (OGTT). However, among the high-risk South Asia...

    Authors: Everlina MA Vlaar, Wanda M Admiraal, Wim B Busschers, Frits Holleman, Vera Nierkens, Barend JC Middelkoop, Karien Stronks and Irene GM van Valkengoed
    Citation: BMC Endocrine Disorders 2013 13:8
  31. Obesity is a major risk factor for type 2 diabetes mellitus (T2DM). A proper anthropometric characterisation of T2DM risk is essential for disease prevention and clinical risk assessement.

    Authors: José María Huerta, María-José Tormo, María-Dolores Chirlaque, Diana Gavrila, Pilar Amiano, Larraitz Arriola, Eva Ardanaz, Laudina Rodríguez, María-José Sánchez, Michelle Mendez, Diego Salmerón, Aurelio Barricarte, Rosana Burgui, Miren Dorronsoro, Nerea Larrañaga, Esther Molina-Montes…
    Citation: BMC Endocrine Disorders 2013 13:7
  32. Insulin resistance is frequent in human immunodeficiency virus (HIV) infection and may be related to antiretroviral therapy. Cytokines secreted by adipose tissue (adipokines) are linked to insulin sensitivity....

    Authors: Victoria Arama, Catalin Tiliscan, Adrian Streinu-Cercel, Daniela Ion, Raluca Mihailescu, Daniela Munteanu, Adriana Hristea and Stefan Sorin Arama
    Citation: BMC Endocrine Disorders 2013 13:4
  33. Adrenal insufficiency is a rare and potentially lethal disease if untreated. Several clinical signs and biological markers are associated with glucocorticoid failure but the importance of these factors for dia...

    Authors: Jean-Baptiste Oboni, Pedro Marques-Vidal, François Pralong and Gérard Waeber
    Citation: BMC Endocrine Disorders 2013 13:3
  34. The mechanism behind parathyroid hormone (PTH) activation of bone remodeling is intimately dependent on the time of exposure of bone cells to hormone levels. Sustained high PTH levels trigger catabolism, while...

    Authors: Maira L Mendonça, Francisco A Pereira, Marcello H Nogueira-Barbosa, Lucas M Monsignore, Sara R Teixeira, Plauto CA Watanabe, Lea MZ Maciel and Francisco JA de Paula
    Citation: BMC Endocrine Disorders 2013 13:1
  35. Severe hypoglycaemia (SH) is one of the most feared complications of type 1 diabetes (T1DM) with a reported prevalence of nearly 40%. In randomized trials of Multiple Daily Injections (MDI) and Continuous Subc...

    Authors: Stuart Little, Thomas Chadwick, Pratik Choudhary, Cath Brennand, Julia Stickland, Shalleen Barendse, Tolulope Olateju, Lalantha Leelarathna, Emma Walkinshaw, Horng K Tan, Sally M Marshall, Reena M Thomas, Simon Heller, Mark Evans, David Kerr, Daniel Flanagan…
    Citation: BMC Endocrine Disorders 2012 12:33
  36. The use of chromium supplements is widespread for the prevention and treatment of diabetes mellitus but there are conflicting reports on efficacy, possibly reflecting discrepant effects across different popula...

    Authors: Umesh Masharani, Christine Gjerde, Shelley McCoy, Betty A Maddux, Danielle Hessler, Ira D Goldfine and Jack F Youngren
    Citation: BMC Endocrine Disorders 2012 12:31
  37. Gastroenteropancreatic neuroendocrine neoplasm (GEP-NEN) is the most common type of neuroendocrine tumors accounting for 65–75% of neuroendocrine neoplasms (NENs). Given the fact that there are few studies on ...

    Authors: Yu-hong Wang, Yuan Lin, Ling Xue, Jin-hui Wang, Min-hu Chen and Jie Chen
    Citation: BMC Endocrine Disorders 2012 12:30
  38. Thyroid hemiagenesis is a rare anomaly, more commonly seen on the left side (ratio 4:1) and in females (ratio 3:1). The first to describe this anomaly was Handfield Jones in 1852.

    Authors: Merima Oruci, Yasuhiro Ito, Marko Buta, Ziv Radisavljevic, Gordana Pupic, Igor Djurisic and Radan Dzodic
    Citation: BMC Endocrine Disorders 2012 12:29
  39. Structured education programmes are now established as an essential component to assist effective self-management of diabetes. In the case of Type 1 diabetes, the Dose Adjustment For Normal Eating (DAFNE) prog...

    Authors: Jackie Elliott, Julia Lawton, David Rankin, Celia Emery, Mike Campbell, Simon Dixon and Simon Heller
    Citation: BMC Endocrine Disorders 2012 12:28
  40. Vitamin D deficiency is associated with multiple adverse health outcomes including increased morbidity and mortality in the general population and in critically ill patients. However, no randomized controlled ...

    Authors: Karin Amrein, Christian Schnedl, Andrea Berghold, Thomas R Pieber and Harald Dobnig
    Citation: BMC Endocrine Disorders 2012 12:27
  41. In addition to stimulating linear growth in children, growth hormone (GH) influences metabolism and body composition. These effects should be considered when individualizing GH treatment as dose-dependent chan...

    Authors: Ralph Decker, Anders Nygren, Berit Kriström, Andreas FM Nierop, Jan Gustafsson, Kerstin Albertsson-Wikland and Jovanna Dahlgren
    Citation: BMC Endocrine Disorders 2012 12:26
  42. The Metabolic syndrome (MS) which is a constellation of cardiometabolic risk factors including dyslipidaemia, hypertension, hyperglycaemia, central obesity, and endothelial dysfunction was hitherto relatively ...

    Authors: Mawuli Gyakobo, Albert GB Amoah, De-Anne Martey-Marbell and Rachel C Snow
    Citation: BMC Endocrine Disorders 2012 12:25
  43. Oxidative stress has been implicated in the development of type 2 diabetes mellitus. Bilirubin is a potent endogenous antioxidant, and coffee is a major source of exogenous antioxidants. Serum gamma-glutamyltr...

    Authors: Zhenjie Wang, Christopher McMonagle, Shinichiro Yoshimitsu, Sanjeev Budhathoki, Makiko Morita, Kengo Toyomura, Keizo Ohnaka, Ryoichi Takayanagi and Suminori Kono
    Citation: BMC Endocrine Disorders 2012 12:24
  44. Hypoglycaemia is a serious adverse effect of antidiabetic drug therapy. We aimed to determine incidence rates of hypoglycaemia in type-2 diabetic patients and identify predictors of hypoglycaemia when treatmen...

    Authors: Diethelm Tschöpe, Peter Bramlage, Christiane Binz, Michael Krekler, Evelin Deeg and Anselm K Gitt
    Citation: BMC Endocrine Disorders 2012 12:23
  45. Obesity is a major worldwide health problem. It is commonly observed in Down syndrome individuals than in the general population. The reason for increased risk of obesity in DS is unclear.

    Authors: Sohier Yahia, Reham M EL-farahaty, Amany K El-Hawary, Mona A El-hussiny, Hanaa Abdel-maseih, Faeza El-Dahtory and Abdel-Hady El-Gilany
    Citation: BMC Endocrine Disorders 2012 12:22
  46. The uncertainties regarding dose similarities between basal long-acting insulin analogues remain. Recent real-world studies indicate dose similarities between insulin detemir and insulin glargine, but further ...

    Authors: Marie Jakobsen, Mette Dalsgaard, Morten Hørmann and Daniél Vega Møller
    Citation: BMC Endocrine Disorders 2012 12:21

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