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  1. The ubiquitin conjugating enzyme E2L3 (UBE2L3) gene is associated with susceptibility to many autoimmune diseases. The aim of this study was to investigate the association between UBE2L3 gene and autoimmune th...

    Authors: Yu Wang, Yuan-feng Zhu, Qiong Wang, Jing Xu, Ni Yan, Jian Xu, Liang-feng Shi, Shuang-tao He and Jin-an Zhang
    Citation: BMC Endocrine Disorders 2016 16:18
  2. Islet cell transplantation is a method to stabilize type 1 diabetes patients with hypoglycemia unawareness and unstable blood glucose levels by reducing insulin dependency and protecting against severe hypogly...

    Authors: Klemens Wallner, A. M. James Shapiro, Peter A. Senior and Christopher McCabe
    Citation: BMC Endocrine Disorders 2016 16:17
  3. Many patients with acromegaly do not achieve biochemical control with first-generation somatostatin analogues. A large, multicenter, randomized, Phase III core study demonstrated that pasireotide LAR had signi...

    Authors: Marcello D. Bronstein, Maria Fleseriu, Sebastian Neggers, Annamaria Colao, Michael Sheppard, Feng Gu, Chiung-Chyi Shen, Mônica Gadelha, Andrew J. Farrall, Karina Hermosillo Reséndiz, Matthieu Ruffin, YinMiao Chen and Pamela Freda
    Citation: BMC Endocrine Disorders 2016 16:16
  4. Women with type 2 diabetes mellitus (T2DM) have a higher risk of fractures despite increased bone mineral density (BMD). In experimental studies a potential role of plasminogen activator inhibitor-1 (PAI-1) in...

    Authors: Silvija Canecki-Varžić, Ivana Prpić-Križevac and Ines Bilić-Ćurčić
    Citation: BMC Endocrine Disorders 2016 16:14
  5. The number and activity of circulating endothelial progenitor cells (EPCs) in prehypertension is preserved in premenopausal women. However, whether this favorable effect still exists in prehypertensive premeno...

    Authors: Haitao Zeng, Yanping Jiang, Hailin Tang, Zi Ren, Gaofeng Zeng and Zhen Yang
    Citation: BMC Endocrine Disorders 2016 16:13
  6. There is rising incidence of gastroenteropancreatic neuroendocrine tumours (GEP- NETs) in many parts of the world, but epidemiological data from Asian populations is rare.

    Authors: Doris T. Chan, Andrea O. Y. Luk, W. Y. So, Alice P. S. Kong, Francis C. C. Chow, Ronald C. W. Ma and Anthony W. I. Lo
    Citation: BMC Endocrine Disorders 2016 16:12
  7. The relationship between alterations in thyroid function and cognitive deficits has been investigated in several previous studies. Hypo-or hyperthyroidism and, to a lesser extent, subclinical thyroid dysfuncti...

    Authors: Yao Hu, Zhi-cheng Wang, Qi-hao Guo, Wei Cheng and Yan-wen Chen
    Citation: BMC Endocrine Disorders 2016 16:11
  8. Information about the achievement of glycemic targets in patients with type 2 diabetes according to different individualization strategies is scarce. Our aim was to analyze the allocation of type 2 diabetic pa...

    Authors: I. Miñambres, J. J. Mediavilla, J. Sarroca and A. Pérez
    Citation: BMC Endocrine Disorders 2016 16:10
  9. The rare incidence of neuroendocrine neoplasms (NENs) has contributed to a paucity of large epidemiologic studies of patients with this condition. We investigated the occurrence and clinicopathologic features ...

    Authors: George C. Nikou, Kalliopi Pazaitou-Panayiotou, Dimitrios Dimitroulopoulos, Georgios Alexandrakis, Pavlos Papakostas, Michalis Vaslamatzis, Philippos Kaldrymidis, Vyron Markussis and Anna Koumarianou
    Citation: BMC Endocrine Disorders 2016 16:8
  10. Experiments in mice initially suggested a role for the protein angiopoietin-like 8 (ANGPTL8) in glucose homeostasis. However, subsequent experiments in model systems have challenged this proposed role. We soug...

    Authors: Katharine R. Clapham, Audrey Y. Chu, Jennifer Wessel, Pradeep Natarajan, Jason Flannick, Manuel A. Rivas, Samantha Sartori, Roxana Mehran, Usman Baber, Valentin Fuster, Robert A. Scott, Daniel J. Rader, Michael Boehnke, Mark I. McCarthy, David M. Altshuler, Sekar Kathiresan…
    Citation: BMC Endocrine Disorders 2016 16:7
  11. The metabolic impact of participating in a diabetes camp is little known among children and adolescents living with type 1 diabetes in sub-Saharan Africa. We aimed to assess the changes in glycemic control and...

    Authors: Mesmin Y. Dehayem, Rémy Takogue, Siméon-Pierre Choukem, Olivier T. S. Donfack, Jean-Claude Katte, Suzanne Sap, Eugène Sobngwi and Jean-Claude Mbanya
    Citation: BMC Endocrine Disorders 2016 16:5
  12. Hospital inpatient care for patients with diabetes was estimated to cost $76 billion in 2012. Substantial expense resulted from those patients having multiple hospitalizations. The objective was to compare the...

    Authors: Pamela C. Heaton, Vibha C. A. Desai, Christina M. L. Kelton and Swapnil N. Rajpathak
    Citation: BMC Endocrine Disorders 2016 16:4
  13. Aldosterone-producing adrenocortical carcinoma is a rare malignancy, which is usually diagnosed by histopathological examination of the excised tumor. In inoperable cases, aldosterone-producing ACC diagnosed b...

    Authors: Kennosuke Ohashi, Takeshi Hayashi, Masaya Sakamoto, Hiroyuki Iuchi, Hirofumi Suzuki, Takanori Ebisawa, Katsuyoshi Tojo, Hironobu Sasano and Kazunori Utsunomiya
    Citation: BMC Endocrine Disorders 2016 16:3
  14. Isolated adrenocorticotropic hormone (ACTH) deficiency is a pituitary disorder characterized by reduction only in the secretion of ACTH. Although the underlying mechanism remains to be elucidated, numbers of c...

    Authors: Yukihiro Goto, Kazunori Tatsuzawa, Kazuyasu Aita, Yuichi Furuno, Takuya Kawabe, Kei Ohwada, Hiroyasu Sasajima and Katsuyoshi Mineura
    Citation: BMC Endocrine Disorders 2016 16:2
  15. Resistance to thyroid hormone beta (RTHβ) is a rare and usually dominantly inherited syndrome caused by mutations of the thyroid hormone receptor β gene (THRB). In severe cases, it is rarely challenging to contro...

    Authors: Yoshihiro Maruo, Asami Mori, Yoriko Morioka, Chihiro Sawai, Yu Mimura, Katsuyuki Matui and Yoshihiro Takeuchi
    Citation: BMC Endocrine Disorders 2016 16:1
  16. Responsiveness to GH treatment can be estimated by both growth and ∆IGF-I. The primary aim of the present study was to investigate if mimicking the physiological increase during puberty in GH secretion, by usi...

    Authors: Elena Lundberg, Berit Kriström, Bjorn Jonsson and Kerstin Albertsson-Wikland
    Citation: BMC Endocrine Disorders 2015 15:84
  17. The prevalence of pediatric hormonal disorders and hormonally-sensitive cancers are rising. Chemicals including bisphenol A (BPA), phthalates, parabens, 4-nonylphenol (4NP) and triclosan have been linked to di...

    Authors: Erin Speiser Ihde, Ji Meng Loh and Lawrence Rosen
    Citation: BMC Endocrine Disorders 2015 15:83

    The Erratum to this article has been published in BMC Endocrine Disorders 2016 16:6

  18. Neurofibromatosis type 1 (NF1) is a common autosomal dominant genetic disorder with an extremely variable phenotype. In childhood NF1 can be associated with optic glioma and central precocious puberty; the lat...

    Authors: Mirjana Kocova, Elena Kochova and Elena Sukarova-Angelovska
    Citation: BMC Endocrine Disorders 2015 15:82
  19. Denosumab is a fully human monoclonal antibody that inhibits receptor activator of nuclear factor kappa-β ligand (RANKL). Previous reports have shown that denosumab treatment of osteoporotic patients decreases...

    Authors: Yukio Nakamura, Mikio Kamimura, Shota Ikegami, Keijiro Mukaiyama, Shigeharu Uchiyama, Akira Taguchi and Hiroyuki Kato
    Citation: BMC Endocrine Disorders 2015 15:81
  20. The aim of the present study of the general population was to identify the best predictor of metabolic risk among the body index variables evaluated with dual-energy X-ray absorptiometry (DEXA) or anthropometr...

    Authors: Seok Hui Kang, Kyu Hyang Cho, Jong Won Park and Jun Young Do
    Citation: BMC Endocrine Disorders 2015 15:79
  21. The main purpose of the present study is to evaluate whether treatment with long-acting human glucagon-like peptide-1 liraglutide was associated with an improvement of excessive daytime sleepiness (EDS) in obe...

    Authors: Fernando Gomez-Peralta, Cristina Abreu, Jose Carlos Castro, Elvira Alcarria, Margarita Cruz-Bravo, Maria Jesús Garcia-Llorente, Cristina Albornos, Concepción Moreno, María Cepeda and Francisca Almodóvar
    Citation: BMC Endocrine Disorders 2015 15:78
  22. Type 2 diabetic patients display significantly higher incidence of cardiovascular (CV) events including stroke compared to non-diabetics. Morning blood pressure surge (MBPS) and blunted systolic night-day (SND...

    Authors: Johanne M. Lyhne, Esben Laugesen, Pernille Høyem, Simon Cichosz, Jens S. Christiansen, Søren T. Knudsen, Klavs W. Hansen, Troels K. Hansen and Per L. Poulsen
    Citation: BMC Endocrine Disorders 2015 15:77
  23. Recombinant Growth hormone (rGH) therapy is approved in many countries for treatment of short stature in a number of childhood diagnoses. Despite the increasing body of international literature on rGH use, the...

    Authors: Dalia Al-Abdulrazzaq, Abdullah Al-Taiar, Kholoud Hassan and Iman Al-Basari
    Citation: BMC Endocrine Disorders 2015 15:76
  24. High osteoprotegerin (OPG) has been reported in association with insulin resistance and type 2 diabetes. We aimed to evaluate the association of serum OPG with impaired glucose regulation (IGR) and microalbumi...

    Authors: Yixin Niu, Zhen Yang, Xiaoyong Li, Weiwei Zhang, Shuai Lu, Hongmei Zhang, Xueru Chen, Lingfei Zhu, Yin Xing, Guang Ning, Li Qin and Qing Su
    Citation: BMC Endocrine Disorders 2015 15:75
  25. Alterations in intestinal microbiota correlate with risk of development of obesity and type 2 diabetes. Probiotics have been suggested to play an important role in the management of dysglycemia, although the e...

    Authors: Qun Yan, Xu Li and Bo Feng
    Citation: BMC Endocrine Disorders 2015 15:74
  26. To evaluate the efficacy, safety, pain perception and health-related quality of life (QoL) of percutaneous ethanol injection treatment (PEIT) as an alternative to thyroid surgery in symptomatic thyroid cysts.

    Authors: Jordi L. Reverter, Núria Alonso, Marta Avila, Anna Lucas, Dídac Mauricio and Manel Puig-Domingo
    Citation: BMC Endocrine Disorders 2015 15:73
  27. Ectopic production of adrenocorticotropic hormone (ACTH) by neuroendocrine tumours (NET) is a rare condition, occult presentations often hampering the diagnosis. Although NET are relatively frequent in the ile...

    Authors: Diana Loreta Paun, Lavinia Vija, Emilia Stan, Alexandra Banica, Elena Bobeica, Dana Terzea, Catalina Poiana, Corin Badiu and Sorin Paun
    Citation: BMC Endocrine Disorders 2015 15:72
  28. The aim of this study was to investigate whether body composition, dietary pattern and habitual physical activity are associated with BMD according to time since menopause in women from Southern Brazil with no...

    Authors: Thaís R. Silva, Roberta Franz, Maria A. Maturana and Poli M. Spritzer
    Citation: BMC Endocrine Disorders 2015 15:71
  29. Ectopic thyroid is a rare disease. In the present study at the 9th People’s Hospital in Shanghai, China, 42 patients’ ectopic thyroid glands between the neck and maxillofacial region were subjected to a retros...

    Authors: Ting Gu, Boren Jiang, Ningjian Wang, Fangzhen Xia, Lizhen Wang, Aichun Gu, Feng Xu, Yongshun Han, Qin Li and Yingli Lu
    Citation: BMC Endocrine Disorders 2015 15:70
  30. The nonthyroidal illness syndrome (NTIS) is prevalent among patients with enterocutaneous fistula and is associated with poor outcomes. The present study aimed to explore the role of enteral nutrition (EN) the...

    Authors: Ranran Li, Jianan Ren, Qin Wu, Gefei Wang, Xiuwen Wu, Jun Chen, Guanwei Li, Zhiwu Hong, Huajian Ren, Yunzhao Zhao and Jieshou Li
    Citation: BMC Endocrine Disorders 2015 15:69
  31. Coexisting of Graves’ disease and functioning struma ovarii is a rare condition. Although the histology of struma ovarii predominantly composed of thyrocytes, the majority of the patients did not have thyrotox...

    Authors: Tullaya Sitasuwan, Suchanan Hanamornroongruang, Thavatchai Peerapatdit and Nuntakorn Thongtang
    Citation: BMC Endocrine Disorders 2015 15:68
  32. Canagliflozin, an oral agent that inhibits sodium glucose co-transporter 2, improves glycemic control, body weight, and blood pressure and is generally well tolerated in patients with type 2 diabetes mellitus ...

    Authors: Erin K. Buysman, Wing Chow, Henry J. Henk and Marcia F. T. Rupnow
    Citation: BMC Endocrine Disorders 2015 15:67
  33. Hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome is a rare autosomal dominant disorder caused by mutations in the zinc finger transcription factor gene, GATA3. GATA3 has 2 zinc finger domains, whi...

    Authors: Tetsuji Okawa, Masanori Yoshida, Takeshi Usui, Takahiro Kudou, Yasumasa Iwasaki, Kazuki Fukuoka, Norio Takahashi, Yuka Uehara and Yutaka Oiso
    Citation: BMC Endocrine Disorders 2015 15:66
  34. Chronic kidney disease (CKD) is becoming a serious health problem; the number of people with impaired renal function is rapidly rising. Progression of CKD is associated with having a number of complications, i...

    Authors: Saroj Khatiwada, Rajendra KC, Sharad Gautam, Madhab Lamsal and Nirmal Baral
    Citation: BMC Endocrine Disorders 2015 15:65
  35. This is the first case report of focal seizure as a manifestation of Immunoglobulin G4 (IgG4)-related hypophysitis. IgG4-related hypophysitis is a novel category of hypophysitis. The clinical presentations, im...

    Authors: Kanchana Ngaosuwan, Therdkiat Trongwongsa and Shanop Shuangshoti
    Citation: BMC Endocrine Disorders 2015 15:64
  36. Overweight and obesity are common among patients with Cushing’s syndrome (CS) and may persist in some patients even after ostensibly curative surgery, contributing to cardiometabolic dysfunction and increased ...

    Authors: Henry G. Fein, T. Brooks Vaughan III, Harvey Kushner, David Cram and Dat Nguyen
    Citation: BMC Endocrine Disorders 2015 15:63
  37. Cushing’s disease is an ACTH-producing pituitary adenoma, and the primary treatment is microscopic or endoscopic transsphenoidal selective adenectomy. The aims of the present study were to evaluate whether the...

    Authors: Jon Ramm-Pettersen, Helene Halvorsen, Johan Arild Evang, Pål Rønning, Per Kristian Hol, Jens Bollerslev, Jon Berg-Johnsen and Eirik Helseth
    Citation: BMC Endocrine Disorders 2015 15:62
  38. Addison’s disease, or primary adrenal insufficiency, is often associated with reduced well-being and fatigue despite use of currently recommended adrenal hormone replacement. Hypoglycaemia is a known manifesta...

    Authors: Kristina S Petersen, R. Louise Rushworth, Peter M Clifton and David J Torpy
    Citation: BMC Endocrine Disorders 2015 15:61
  39. Central precocious puberty (CPP) is often familial but its genetic cause is largely unknown. Very recently, the makorin RING finger protein 3 (MKRN3) gene, located on chromosome 15 in the Prader-Willi syndrome (P...

    Authors: Anna Grandone, Grazia Cantelmi, Grazia Cirillo, Pierluigi Marzuillo, Caterina Luongo, Emanuele Miraglia del Giudice and Laura Perrone
    Citation: BMC Endocrine Disorders 2015 15:60
  40. Foot ulceration is the main precursor to lower limb amputation in patients with type 2 diabetes worldwide. Biomechanical factors have been implicated in the development of foot ulceration; however the associat...

    Authors: Malindu Eranga Fernando, Robert George Crowther, Margaret Cunningham, Peter Anthony Lazzarini, Kunwarjit Singh Sangla and Jonathan Golledge
    Citation: BMC Endocrine Disorders 2015 15:59
  41. Agenesis of the internal carotid artery (ICA) is a rare congenital abnormality, sporadically reported to be associated with a combined congenital hypopituitarism. Nevertheless, only a few cases have been exten...

    Authors: Stefano Stagi, Giovanna Traficante, Elisabetta Lapi, Marilena Pantaleo, Sabrina Becciani, Marzia Mortilla, Salvatore Seminara and Maurizio de Martino
    Citation: BMC Endocrine Disorders 2015 15:58
  42. Diabetes mellitus (DM) leads to multiple complications, including severe hypoglycaemia events (SHEs). SHEs can impact a patient’s quality of life and compliance and may directly result in additional costs to t...

    Authors: Marcin Czech, Elżbieta Rdzanek, Justyna Pawęska, Olga Adamowicz-Sidor, Maciej Niewada and Michał Jakubczyk
    Citation: BMC Endocrine Disorders 2015 15:57
  43. We evaluate the combined effect of the presence of elevated depressive symptoms and antidepressant medication use with respect to risk of type 2 diabetes among approximately 120,000 women enrolled in the Women...

    Authors: Christine Frisard, Xiangdong Gu, Brian Whitcomb, Yunsheng Ma, Penelope Pekow, Martha Zorn, Deidre Sepavich and Raji Balasubramanian
    Citation: BMC Endocrine Disorders 2015 15:56
  44. Although monitoring foot skin temperatures has been associated with diabetic foot ulcer recurrence, no studies have been carried out to test the feasibility among European Caucasians. Moreover, the educational...

    Authors: Anita Skafjeld, Marjolein. M. Iversen, Ingar Holme, Lis Ribu, Kjetil Hvaal and Bente. K. Kilhovd
    Citation: BMC Endocrine Disorders 2015 15:55
  45. In patients with type-2 diabetes receiving oral antidiabetic drugs (OADs), the addition of insulin is frequently required to achieve sufficient control over blood glucose levels. It is, however, difficult to p...

    Authors: Thomas Danne, Tobias Bluhmki, Jochen Seufert, Matthias Kaltheuner, Wolfgang Rathmann, Jan Beyersmann and Peter Bramlage
    Citation: BMC Endocrine Disorders 2015 15:54
  46. Vitamin D deficiency has been associated with acute stroke and other cardiovascular diseases in the developed world. Low 25-hydroxyvitamin D (25OHD) has been described in some populations in Sub-Saharan Africa...

    Authors: Daniel S. Kiggundu, Edrisa Mutebi, Davis Kibirige, Rebecca Boxer, Barbara Kakande, Brian K. Kigozi and Elly Katabira
    Citation: BMC Endocrine Disorders 2015 15:53

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