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  1. Ectopic adrenocorticotropic hormone (ACTH) syndrome (EAS) is caused by tumours releasing ACTH. Ectopic ACTH-producing tumour regression is rarely induced using steroidogenesis inhibitors. We presented a case o...

    Authors: Hideyuki Iwayama, Sho Hirase, Yuka Nomura, Tatsuo Ito, Hiroyuki Morita, Kazuo Otake, Akihisa Okumura and Junko Takagi
    Citation: BMC Endocrine Disorders 2018 18:19
    Content type: Case report Published on:

  2. Here, we report a case of central pontine demyelinization in a type-2 diabetes patient with hyperglycemia after a binge-eating attack in the absence of a relevant hyponatremia.

    Authors: Rainer U. Pliquett, Arno Noll, Richard Ibe, Alexandra Katz, Charlotte Ackmann, Alexandra Schreiber and Matthias Girndt
    Citation: BMC Endocrine Disorders 2018 18:18
    Content type: Case report Published on:

  3. Thyroid nodules are highly prevalent, but a robust, feasible method for malignancy differentiation has not yet been well documented. This study aimed to establish a practical model for thyroid nodule discrimin...

    Authors: Jia Liu, Dongmei Zheng, Qiang Li, Xulei Tang, Zuojie Luo, Zhongshang Yuan, Ling Gao and Jiajun Zhao
    Citation: BMC Endocrine Disorders 2018 18:17
    Content type: Research article Published on:

  4. The evaluation of metabolic syndrome in a society predisposed to the diabetes mellitus epidemic opens a new avenue to understanding this rapidly growing global metabolic problem. Although Saudi Arabia reports ...

    Authors: Khalid Al-Rubeaan, Nahla Bawazeer, Yousuf Al Farsi, Amira M. Youssef, Abdulrahman A. Al-Yahya, Hamid AlQumaidi, Basim M. Al-Malki, Khalid A. Naji, Khalid Al-Shehri and Fahd I. Al Rumaih
    Citation: BMC Endocrine Disorders 2018 18:16
    Content type: Research article Published on:

  5. The aim of this study was to quantify the association of Val109Asp polymorphism of intelectin 1 (ITLN1) gene with the abdominal obesity (AO) in Kyrgyz population.

    Authors: Jainagul Isakova, Elnura Talaibekova, Denis Vinnikov, Nazira Aldasheva, Erkin Mirrakhimov and Almaz Aldashev
    Citation: BMC Endocrine Disorders 2018 18:15
    Content type: Research article Published on:

  6. Impaired insulin activity in women with polycystic ovary syndrome might differ from that seen in type 2 diabetes mellitus without polycystic ovary syndrome. This study was designed to compare the effects of tr...

    Authors: Tao Tao, Peihong Wu, Yuying Wang and Wei Liu
    Citation: BMC Endocrine Disorders 2018 18:14
    Content type: Research article Published on:

  7. Intravenous glucocorticoids (ivGC) have been recommended as a first-line treatment of moderate-to-severe and active thyroid-associated ophthalmopathy (TAO). However, not all patients are responsive to ivGC. Th...

    Authors: Yang Wang, Shuo Zhang, Yidan Zhang, Xingtong Liu, Hao Gu, Sisi Zhong, Yazhuo Huang, Sijie Fang, Jing Sun, Huifang Zhou and Xianqun Fan
    Citation: BMC Endocrine Disorders 2018 18:13
    Content type: Research article Published on:

  8. Continuous glucose monitoring (CGM) enables users to view real-time interstitial glucose readings and provides information on the direction and rate of change of blood glucose levels. Users can also access his...

    Authors: J. Lawton, M. Blackburn, J. Allen, F. Campbell, D. Elleri, L. Leelarathna, D. Rankin, M. Tauschmann, H. Thabit and R. Hovorka
    Citation: BMC Endocrine Disorders 2018 18:12
    Content type: Research article Published on:

  9. Many studies have reported associations between estrogen receptor (ER) gene polymorphisms and postmenopausal osteoporosis (PMOP) risk and bone mineral density (BMD), but the results are controversial. The aim ...

    Authors: Heping Zhu, Jiannong Jiang, Qiang Wang, Jun Zong, Liang Zhang, Tieliang Ma, Youjia Xu and Leiyan Zhang
    Citation: BMC Endocrine Disorders 2018 18:11
    Content type: Research article Published on:

  10. The adverse effects of growth hormone (GH) deficiency (GHD) in adults (AGHD) on metabolism and health-related quality of life (HRQoL) can be improved with GH substitution. This investigation aimed to design a ...

    Authors: Peter H. Kann, Simona Bergmann, Martin Bidlingmaier, Christina Dimopoulou, Birgitte T. Pedersen, Günter K. Stalla, Matthias M. Weber and Stefanie Meckes-Ferber
    Citation: BMC Endocrine Disorders 2018 18:10
    Content type: Research article Published on:

  11. Limited real-world data are currently available on hypoglycemia in diabetes patients. The International Operations Hypoglycemia Assessment Tool (IO HAT) study was designed to estimate hypoglycemia in insulin-t...

    Authors: Rıfat Emral, Tamer Tetiker, Ibrahim Sahin, Ramazan Sari, Ahmet Kaya, İlhan Yetkin, Sefika Uslu Cil and Neslihan Başcıl Tütüncü
    Citation: BMC Endocrine Disorders 2018 18:9
    Content type: Research article Published on:

  12. Ultrasensitive assays to measure pre-pubertal gonadotropins levels could help identify patients with Turner syndrome (TS) in mid-childhood, but studies in this field are scarce. The aim of this study was to an...

    Authors: Stela Carpini, Annelise Barreto Carvalho, Sofia Helena Valente de Lemos-Marini, Gil Guerra-Junior and Andréa Trevas Maciel-Guerra
    Citation: BMC Endocrine Disorders 2018 18:8
    Content type: Research article Published on:

  13. Thyroid eye disease (TED) is a debilitating autoimmune orbital disease that is often a result of Graves’ disease. Dysthyroid optic neuropathy (DON) is a rare but sight-threatening manifestation of TED with the...

    Authors: Shuo Zhang, Yang Wang, Sisi Zhong, Xingtong Liu, Yazhuo Huang, Sijie Fang, Ai Zhuang, Yinwei Li, Jing Sun, Huifang Zhou and Xianqun Fan
    Citation: BMC Endocrine Disorders 2018 18:7
    Content type: Case report Published on:

  14. Although current beta cell replacement therapy is effective in stabilizing glycemic control in highly selected patients with refractory type 1 diabetes, many hurdles are inherent to this and other donor-based ...

    Authors: Klemens Wallner, Rene G. Pedroza, Isaac Awotwe, James M. Piret, Peter A. Senior, A. M. James Shapiro and Christopher McCabe
    Citation: BMC Endocrine Disorders 2018 18:6
    Content type: Research article Published on:

  15. Increased knowledge concerning the differences in the illness perception and self-management among sexes is needed for planning proper support programs for patients with diabetes. The aim of this study was to ...

    Authors: Wimonrut Boonsatean, Anna Carlsson, Irena Dychawy Rosner and Margareta Östman
    Citation: BMC Endocrine Disorders 2018 18:5
    Content type: Research article Published on:

  16. Gestational diabetes insipidus (GDI) is a rare endocrine complication during pregnancy that is associated with vasopressinase overproduction from the placenta. Although increased vasopressinase is associated w...

    Authors: Tatsuya Kondo, Miwa Nakamura, Sayaka Kitano, Junji Kawashima, Takeshi Matsumura, Takashi Ohba, Munekage Yamaguchi, Hidetaka Katabuchi and Eiichi Araki
    Citation: BMC Endocrine Disorders 2018 18:4
    Content type: Case report Published on:

  17. The association between thyroid nodules and adiposity remains controversial. We performed a cross-sectional, community-based study to examine whether thyroid nodules are associated with overweight and obesity,...

    Authors: Bin Song, Zhihua Zuo, Juan Tan, Jianjin Guo, Weiping Teng, Yibing Lu and Chao Liu
    Citation: BMC Endocrine Disorders 2018 18:3
    Content type: Research article Published on:

  18. The approach to acromegalic patients with persistent acromegaly after surgery and inadequate response to first-generation somatostatin receptor ligands (SRLs) should be strictly tailored. Current options inclu...

    Authors: A. Ciresi, S. Radellini, V. Guarnotta and C. Giordano
    Citation: BMC Endocrine Disorders 2018 18:2
    Content type: Case report Published on:

  19. This retrospective study investigated the effect of adding metformin to pharmacologic insulin dosing in type 1 diabetics on insulin therapy 1 year after treatment compared with patients on insulin therapy alone.

    Authors: Selvihan Beysel, Ilknur Ozturk Unsal, Muhammed Kizilgul, Mustafa Caliskan, Bekir Ucan and Erman Cakal
    Citation: BMC Endocrine Disorders 2018 18:1
    Content type: Research article Published on:

  20. Diabetes is one of the most common metabolic disorders, with a high prevalence of patients with poor metabolic control. Worldwide, evidence highlights the importance of developing and implementing educational ...

    Authors: Maria do Rosário Pinto, Pedro Miguel Dinis Santos Parreira, Marta Lima Basto and Lisete dos Santos Mendes Mónico
    Citation: BMC Endocrine Disorders 2017 17:77
    Content type: Research article Published on:

  21. Metabolic syndrome is a cluster of the most dangerous heart attack risk factors such as diabetes and prediabetes, abdominal obesity, high cholesterol and high blood pressure. Hyperuricemia is a condition in wh...

    Authors: Shiferaw Bekele Woyesa, Agete Tadewose Hirigo and Temesgen Bizuayehu Wube
    Citation: BMC Endocrine Disorders 2017 17:76
    Content type: Research article Published on:

  22. We investigated how four aspects of socio-demography influence the effectiveness of an intervention with structured personal diabetes care on long-term outcomes.

    Authors: Andreas Heltberg, Volkert Siersma, John Sahl Andersen, Christina Ellervik, Henrik Brønnum-Hansen, Jakob Kragstrup and Niels de Fine Olivarius
    Citation: BMC Endocrine Disorders 2017 17:75
    Content type: Research article Published on:

  23. We report a rare case of a juxta-adrenal schwannoma that could not be discriminated from an adrenal tumor before surgical resection and was complicated by bilateral hyperaldosteronism. To the best of our knowl...

    Authors: Naru Babaya, Yukako Makutani, Shinsuke Noso, Yoshihisa Hiromine, Hiroyuki Ito, Yasunori Taketomo, Kazuki Ueda, Hokuto Ushijima, Yoshifumi Komoike, Yuto Yamazaki, Hironobu Sasano, Yumiko Kawabata and Hiroshi Ikegami
    Citation: BMC Endocrine Disorders 2017 17:74
    Content type: Case report Published on:

  24. Type 2 diabetes is associated with substantial cardiovascular morbidity and mortality arising from the high prevalence of cardiovascular risk factors such as hypertension, dyslipidaemia, obesity, poor glycaemi...

    Authors: Mercy W. Kimando, Frederick C. F. Otieno, Elijah N. Ogola and Kenn Mutai
    Citation: BMC Endocrine Disorders 2017 17:73
    Content type: Research article Published on:

  25. Individuals with Diabetes Mellitus (DM) are at increased risk for fracture due to the decrease in bone strength and quality. Serum procollagen type I intact N-terminal (P1NP) and serum C-terminal cross-linking...

    Authors: Dyah Purnamasari, Melisa D. Puspitasari, Bambang Setiyohadi, Pringgodigdo Nugroho and Harry Isbagio
    Citation: BMC Endocrine Disorders 2017 17:72
    Content type: Research article Published on:

  26. Vitamin D (VitD) and parathyroid hormone (PTH) play important roles in calcium metabolism and skeletal homeostasis. Estimates of the VitD status in several European countries show large variations between them...

    Authors: Luís Raposo, Sandra Martins, Daniela Ferreira, João Tiago Guimarães and Ana Cristina Santos
    Citation: BMC Endocrine Disorders 2017 17:71
    Content type: Research article Published on:

  27. Type 2 diabetes (T2D) is a progressive disease that often requires a patient to use multiple antihyperglycemic agents to achieve glycemic control with disease progression. Omarigliptin is a once-weekly dipepti...

    Authors: Seung-Hwan Lee, Ira Gantz, Elizabeth Round, Melanie Latham, Edward A. O’Neill, Paulette Ceesay, Shailaja Suryawanshi, Keith D. Kaufman, Samuel S. Engel and Eseng Lai
    Citation: BMC Endocrine Disorders 2017 17:70
    Content type: Research article Published on:

  29. Randomized clinical trials have shown the efficacy and safety of short-acting exenatide in patients with type 2 diabetes mellitus (T2DM). The aim of this observational study was to investigate the effectivenes...

    Authors: You-Cheol Hwang, Ari Kim, Euna Jo, Yeoree Yang, Jae-Hyoung Cho and Byung-Wan Lee
    Citation: BMC Endocrine Disorders 2017 17:68
    Content type: Research article Published on:

  30. Adipose tissue, an endocrine organ of the body, is involved in some obesity-related disease states such as insulin resistance, diabetes mellitus, and atherosclerosis. Vaspin is a novel adipocyte with insulin s...

    Authors: Wei Yang, Yun Li, Tian Tian, Li Wang, Pearl Lee and Qi Hua
    Citation: BMC Endocrine Disorders 2017 17:67
    Content type: Research article Published on:

  31. Self-care is essential for patients with diabetes mellitus. Both clinicians and researchers must be able to assess the quality of that self-care. Available tools have various limitations and none are theoretic...

    Authors: Davide Ausili, Claudio Barbaranelli, Emanuela Rossi, Paola Rebora, Diletta Fabrizi, Chiara Coghi, Michela Luciani, Ercole Vellone, Stefania Di Mauro and Barbara Riegel
    Citation: BMC Endocrine Disorders 2017 17:66
    Content type: Research article Published on:

  32. The metabolic syndrome (MetS) is a combination of unfavourable health factors which includes abdominal obesity, dyslipidaemia, elevated blood pressure and impaired fasting glucose. Earlier studies have reporte...

    Authors: Bruce H. R. Wolffenbuttel, Hanneke J. C. M. Wouters, Sandra N. Slagter, Robert P. van Waateringe, Anneke C. Muller Kobold, Jana V. van Vliet-Ostaptchouk, Thera P. Links and Melanie M. van der Klauw
    Citation: BMC Endocrine Disorders 2017 17:65
    Content type: Research article Published on:

  33. It is well known that dyslipidemia and chronic hyperglycemia increase the onset of diabetes and diabetic complication. The aim of this study is to see the association of trace metals elements and lipid profile...

    Authors: Amare Desalegn Wolide, Belay Zawdie, Tilahun Alemayehu and Samuel Tadesse
    Citation: BMC Endocrine Disorders 2017 17:64
    Content type: Research article Published on:

  34. Insulin treatment has been associated with a paradoxical worsening of diabetes retinopathy since many years in European cohorts. Recently, this issue has been stressed by some studies conducted in other parts ...

    Authors: Ahmadou M. Jingi, Aurel T. Tankeu, Narcisse Assene Ateba and Jean Jacques Noubiap
    Citation: BMC Endocrine Disorders 2017 17:63
    Content type: Debate Published on:

  35. Recent studies have demonstrated that immune factors might have a role in the pathophysiology of insulin resistance and type 2 diabetes mellitus (T2DM). Inappropriate glycemic control in patients with T2DM is ...

    Authors: Muhammed Kizilgul, Ozgur Ozcelik, Selvihan Beysel, Hakan Akinci, Seyfullah Kan, Bekir Ucan, Mahmut Apaydin and Erman Cakal
    Citation: BMC Endocrine Disorders 2017 17:62
    Content type: Research article Published on:

  37. Recent studies show that bile acids are involved in glucose and energy homeostasis through activation of G protein coupled membrane receptor (TGR5) and farnesoid X receptor (FXR). A few researches have explore...

    Authors: Xinfeng Yan, Peicheng Li, Zhaosheng Tang and Bo Feng
    Citation: BMC Endocrine Disorders 2017 17:60
    Content type: Research article Published on:

  38. Slipped capital femoral epiphysis (SCFE) is a common hip disorder characterized by displacement of the capital femoral epiphysis from the metaphysic through the femoral epiphyseal plate. SCFE usually occurs du...

    Authors: Saori Kadowaki, Tomohiro Hori, Hideki Matsumoto, Kaori Kanda, Michio Ozeki, Yu Shirakami, Norio Kawamoto, Hidenori Ohnishi and Toshiyuki Fukao
    Citation: BMC Endocrine Disorders 2017 17:59
    Content type: Case report Published on:

  39. Adrenal crisis (AC) occurs in various clinical conditions but previous epidemiological studies in AC are limited to chronic adrenal insufficiency (AI) and sepsis. The aim of this study was to investigate chara...

    Authors: Masahiro Iwasaku, Maki Shinzawa, Shiro Tanaka, Kimihiko Kimachi and Koji Kawakami
    Citation: BMC Endocrine Disorders 2017 17:58
    Content type: Research article Published on:

  40. Parathyroid water-clear cell hyperplasia (WCCH) and water-clear cell adenoma (WCCA) are rare causes of primary hyperparathyroidism. The frequency of WCCH seems to be less than 1% of all primary hyperplasia.

    Authors: Georgios Boutzios, Helen Sarlanis, Anna Kolindou, Antigoni Velidaki and Theodore Karatzas
    Citation: BMC Endocrine Disorders 2017 17:57
    Content type: Case report Published on:

  41. The increasing prevalence of diabetes is leading to a rise of eye diseases, augmenting the risk of sight-threatening complications. The aim of this study was to evaluate prevalence, awareness and practices reg...

    Authors: Lazaros Konstantinidis, Tania Carron, Eva de Ancos, Léonie Chinet, Isabelle Hagon-Traub, Emilie Zuercher and Isabelle Peytremann-Bridevaux
    Citation: BMC Endocrine Disorders 2017 17:56
    Content type: Research article Published on:

  42. This study aimed to investigate preoperative somatostatin analogs (SSAs) treatment on the surgical outcome in patients with acromegaly.

    Authors: Lian Duan, Huijuan Zhu, Bing Xing and Feng Gu
    Citation: BMC Endocrine Disorders 2017 17:55
    Content type: Research article Published on:

  43. A functional pituitary adenoma can produce multiple anterior-pituitary hormones, such as growth hormone (GH) -producing adenomas (GHoma) with prolactin or thyrotropin stimulating hormone production in the same...

    Authors: Tomoko Takiguchi, Hisashi Koide, Hidekazu Nagano, Akitoshi Nakayama, Masanori Fujimoto, Ai Tamura, Eri Komai, Akina Shiga, Takashi Kono, Seiichiro Higuchi, Ikki Sakuma, Naoko Hashimoto, Sawako Suzuki, Yui Miyabayashi, Norio Ishiwatari, Kentaro Horiguchi…
    Citation: BMC Endocrine Disorders 2017 17:54
    Content type: Case report Published on:

  44. It has been shown that hepcidin and YKL-40 levels change in persons with insulin resistance in different circumstances. However, variations of the levels of these parameters through the stages of prediabetes a...

    Authors: Driton Vela, Jovica Leshoski, Zana Vela, Muharrem Jakupaj, Mitko Mladenov and Ramadan B. Sopi
    Citation: BMC Endocrine Disorders 2017 17:53
    Content type: Research article Published on:

  45. dsd-LIFE is a comprehensive cross-sectional clinical outcome study of individuals with disorders/differences of sex development (DSD). This study focuses on various rare genetic conditions characterized by imp...

    Authors: Robert Röhle, Katharina Gehrmann, Maria Szarras-Czapnik, Hedi Claahsen-van der Grinten, Catherine Pienkowski, Claire Bouvattier, Peggy Cohen-Kettenis, Anna Nordenström, Ute Thyen and Birgit Köhler
    Citation: BMC Endocrine Disorders 2017 17:52
    Content type: Study protocol Published on:

  46. There are multiple criteria to define remission of type 2 diabetes (DM2) after bariatric surgery but there is not a specific one widely accepted. Our objectives were to compare diagnostic criteria for DM2 remi...

    Authors: María R. Alhambra-Expósito, María J. Molina-Puerta, María I. Prior-Sánchez, Gregorio Manzano-García, Alfonso Calañas-Continente and María A. Gálvez-Moreno
    Citation: BMC Endocrine Disorders 2017 17:51
    Content type: Research article Published on:

  48. Acromegaly is a rare, slowly progressive disorder resulting from excessive growth hormone (GH) production by a pituitary somatotroph tumor. The objective of this study was to examine acromegaly treatment outco...

    Authors: John D. Carmichael, Michael S. Broder, Dasha Cherepanov, Eunice Chang, Adam Mamelak, Qayyim Said, Maureen P. Neary and Vivien Bonert
    Citation: BMC Endocrine Disorders 2017 17:49
    Content type: Research article Published on:

  49. Hypoxia inducible factor 1 (HIF-1) activates protective pathways to counteract hypoxia and prevent tissue damage in conjunction with renal injury. The aim of this study was to evaluate a role of HIF-1 in diabe...

    Authors: Romana Bohuslavova, Radka Cerychova, Katerina Nepomucka and Gabriela Pavlinkova
    Citation: BMC Endocrine Disorders 2017 17:48
    Content type: Research article Published on:

  50. Primary adrenal insufficiency (PAI) is a rare and severe condition requiring lifelong steroid replacement. During acute illness or stressful events, it is important to appropriately adjust glucocorticoid dose;...

    Authors: L. M Shepherd, A. A Tahrani, C Inman, W Arlt and D. M Carrick-Sen
    Citation: BMC Endocrine Disorders 2017 17:47
    Content type: Research article Published on:
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BMC Endocrine Disorders

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