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  1. The aim of the study was to estimate and compare the 8-year cumulative incidence of diabetes mellitus (DM) among Sami and non-Sami inhabitants of rural districts in Northern Norway.

    Authors: Ali Naseribafrouei, Bent Martin Eliassen, Marita Melhus, Johan Svartberg and Ann Ragnhild Broderstad
    Citation: BMC Endocrine Disorders 2019 19:66
  2. For patients with type 2 diabetes (T2D), cardiovascular disease (CVD) is the single most common cause of mortality. In 2008 and 2012, the Federal Drug Administration (FDA) and the European Medicines Agency (EM...

    Authors: Guntram Schernthaner, Heinz Drexel, Evgeny Moshkovich, Birute Zilaitiene, Emil Martinka, Leszek Czupryniak, Tamás Várkonyi, Andrej Janež, Kristine Ducena, Katarina Lalić, Tsvetalina Tankova, Martin Prázný, Lea Smirčić Duvnjak, Olga Sukhareva and Harald Sourij
    Citation: BMC Endocrine Disorders 2019 19:64
  3. Co-existing Cushing’s syndrome and primary aldosteronism caused by bilateral adrenocortical adenomas, secreting cortisol and aldosterone, respectively, have rarely been reported. Precise diagnosis and manageme...

    Authors: Kaiyun Ren, Jia Wei, Qilin Liu, Yuchun Zhu, Nianwei Wu, Ying Tang, Qianrui Li, Qianying Zhang, Yerong Yu, Zhenmei An, Jing Chen and Jianwei Li
    Citation: BMC Endocrine Disorders 2019 19:63
  4. Patients with type 2 diabetes mellitus (T2DM) have accelerated atherosclerosis as a pro thrombotic state that is associated with the platelet activation priming. Platelets, which undergo the continuous mild st...

    Authors: Razie Mahmoodian, Morteza Salimian, Mohsen Hamidpour, Ali Akbar Khadem-Maboudi and Ahmad Gharehbaghian
    Citation: BMC Endocrine Disorders 2019 19:62
  5. Insulin-derived amyloidosis is a skin-related complication of insulin therapy that interferes with insulin therapy. Although toxicities of in vitro-formed insulin amyloid fibrils have been well studied, the to...

    Authors: Keiichi Iwaya, Tamotsu Zako, Junta Fukunaga, Karin Margareta Sörgjerd, Kentaro Ogata, Koichiro Kogure, Hiroshi Kosano, Masayuki Noritake, Mizuo Maeda, Yukio Ando, Yoshiya Katsura and Terumasa Nagase
    Citation: BMC Endocrine Disorders 2019 19:61
  6. Survival from many cancer types is steadily increasing, and as a result, a growing number of cancer patients will live with other chronic diseases, of which diabetes is one of the most prevalent. This study ai...

    Authors: Anne Beiter Arreskov, Maria Å. Olsen, Sandra Sinius Pouplier, Volkert Siersma, Christen L. Andersen, Søren Friis and Niels de Fine Olivarius
    Citation: BMC Endocrine Disorders 2019 19:60
  7. The present study aimed to investigate the inhibitory effects of aminoguanidine (AG) and 2-bromoethylamine (2-BEA) on the semicarbazide-sensitive amine oxidase (SSAO) activity both in vitro and in vivo, and th...

    Authors: Chaosheng Li, Zhenhua Wang, Xiaoli Li and Jun Chen
    Citation: BMC Endocrine Disorders 2019 19:59
  8. In recent years, the relationship between thyroid stimulating hormone (TSH) and obesity has been widely discussed. However, it is unclear how thyroid hormone concentrations relate to body weight and its impact...

    Authors: Ranran Xu, Fei Huang, Shijie Zhang, Yongman Lv and Qingquan Liu
    Citation: BMC Endocrine Disorders 2019 19:58
  9. Although exercise seems to be beneficial for type 2 diabetes mellitus (T2DM) patients, there is limited research elucidating the optimal accessible indices of adiposity and insulin resistance for identifying e...

    Authors: Hong-Ting Zhu, Min Yu, Hao Hu, Qing-Fang He, Jin Pan and Ru-Ying Hu
    Citation: BMC Endocrine Disorders 2019 19:57
  10. Thyrotoxicosis is often caused by destructive thyroiditis (DT) or Graves’ disease (GD), and a prompt and accurate differential diagnosis for thyrotoxicosis is needed as management strategy differs. A meta-anal...

    Authors: Xiaojuan Peng, Shenglan Wu, Caiqun Bie, Huijun Tang, Zhe Xiong and Shaohui Tang
    Citation: BMC Endocrine Disorders 2019 19:56
  11. The diet quality of adults living in the United States has improved overtime. We aim to determine whether diet quality among adults with diabetes mellitus has changed over time, and to examine trends in socioe...

    Authors: Colin J. Orr, Thomas C. Keyserling, Alice S. Ammerman and Seth A. Berkowitz
    Citation: BMC Endocrine Disorders 2019 19:54
  12. Parathyroid carcinoma is a rare neoplasm that may present sporadically or in the context of a genetic syndrome. Diagnosis and management are challenging due to the lack of clinical and pathological features th...

    Authors: Valentina Ferraro, Lucia Ilaria Sgaramella, Giovanna Di Meo, Francesco Paolo Prete, Francesco Logoluso, Francesco Minerva, Marica Noviello, Giuseppina Renzulli, Angela Gurrado and Mario Testini
    Citation: BMC Endocrine Disorders 2019 19(Suppl 1):46

    This article is part of a Supplement: Volume 19 Supplement 1

  13. Medullary thyroid carcinoma is a neuroendocrine tumor belonging form a malignant growth of the thyroid parafollicular C-cells, representing from 1 to 10% of all thyroid cancer. The biochemical activity of medu...

    Authors: Claudio Gambardella, Chiara Offi, Renato Patrone, Guglielmo Clarizia, Claudio Mauriello, Ernesto Tartaglia, Francesco Di Capua, Sergio Di Martino, Roberto Maria Romano, Lorenzo Fiore, Alessandra Conzo, Giovanni Conzo and Giovanni Docimo
    Citation: BMC Endocrine Disorders 2019 19(Suppl 1):45

    This article is part of a Supplement: Volume 19 Supplement 1

  14. The association between Hashimoto’s thyroiditis (HT) and papillary thyroid carcinoma (PTC) is a controversial question that is still under debate, its pathological significance and the eventual clinical implic...

    Authors: Giuseppa Graceffa, Renato Patrone, Salvatore Vieni, Silvia Campanella, Sergio Calamia, Iole Laise, Giovanni Conzo, Mario Latteri and Calogero Cipolla
    Citation: BMC Endocrine Disorders 2019 19(Suppl 1):26

    This article is part of a Supplement: Volume 19 Supplement 1

  15. Hypothyroidism, one of the prevalent endocrine disorders worldwide, has a broad spectrum of clinical manifestations, from an asymptomatic condition to myxedema coma. Although the majority of patients with hypo...

    Authors: Chung Gyo Seo, Kyoung Jin Kim, Euyhyun Park, Nam Hoon Kim, Joo Hyung Kim, Hee Young Kim, Sin Gon Kim and Kyeong Jin Kim
    Citation: BMC Endocrine Disorders 2019 19:52
  16. The molecular basis of the Turkish population with suspected maturity-onset diabetes of the young (MODY) has not been identified. This is the first study to investigate the association between HNF1A-gene single-n...

    Authors: Selvihan Beysel, Nilnur Eyerci, Ferda Alparslan Pinarli, Muhammed Kizilgul, Ozgur Ozcelik, Mustafa Caliskan and Erman Cakal
    Citation: BMC Endocrine Disorders 2019 19:51
  17. Teenagers and young adults with type 1 diabetes (T1D) experience significant burden managing this serious chronic condition and glycaemic control is at its unhealthiest during this life stage. Flash glucose mo...

    Authors: Sara E. Boucher, Andrew R. Gray, Martin de Bock, Esko J. Wiltshire, Barbara C. Galland, Paul A. Tomlinson, Jenny Rayns, Karen E. MacKenzie and Benjamin J. Wheeler
    Citation: BMC Endocrine Disorders 2019 19:50
  18. Ovarian reserve, vital for reproductive function, can be adversely affected by thyroid diseases. Despite alternations of thyroid hormones with ageing, data on interactions between the overtime trend of thyroid...

    Authors: Sara Bahri, Fahimeh Ramezani Tehrani, Atieh Amouzgar, Maryam Rahmati, Maryam Tohidi, Maryam Vasheghani and Fereidoun Azizi
    Citation: BMC Endocrine Disorders 2019 19:47
  19. On average, patients in Japan with type 2 diabetes mellitus have a clinical consultation every month, although evidence for a favorable follow-up interval is lacking. This study investigated whether the follow...

    Authors: Tomohiko Ukai, Shuhei Ichikawa, Miho Sekimoto, Satoru Shikata and Yousuke Takemura
    Citation: BMC Endocrine Disorders 2019 19:43
  20. Some microRNAs are involved in diabetes pathology and some are known to have role in stroke. MiR-503 causes endothelial dysfunction in diabetic patients, predisposing to ischemia. There has been no study evalu...

    Authors: Saba Sheikhbahaei, Danesh Manizheh, Saadatnia Mohammad, Tajaddini Mohamad Hasan, Nazemian Saman, Rafiee Laleh, Motieian Mahsa, Amoushahi Khouzani Sanaz and Haghjooy Javanmard Shaghayegh
    Citation: BMC Endocrine Disorders 2019 19:42
  21. Type 2 diabetes mellitus (T2D) is a leading cause of morbidity and mortality in Mexico. Here, we aimed to report incidence rates (IR) of type 2 diabetes in middle-aged apparently-healthy Mexican adults, identi...

    Authors: Olimpia Arellano-Campos, Donaji V. Gómez-Velasco, Omar Yaxmehen Bello-Chavolla, Ivette Cruz-Bautista, Marco A. Melgarejo-Hernandez, Liliana Muñoz-Hernandez, Luz E. Guillén, Jose de Jesus Garduño-Garcia, Ulices Alvirde, Yukiko Ono-Yoshikawa, Ricardo Choza-Romero, Leobardo Sauque-Reyna, Maria Eugenia Garay-Sevilla, Juan Manuel Malacara-Hernandez, Maria Teresa Tusie-Luna, Luis Miguel Gutierrez-Robledo…
    Citation: BMC Endocrine Disorders 2019 19:41
  22. To analyze data in terms of the glycaemic control and therapeutic regimens used for Type-2 Diabetes Mellitus (T2DM) management in Greece, identify factors that influence clinical decisions and determine the le...

    Authors: Stavros Liatis, Styliani Iraklianou, Kyriakos Kazakos, George Mastorakos, Kostas Milios, Zadalla Mouslech, Marina Noutsou, Emmanouil Pagkalos and Christos Sampanis
    Citation: BMC Endocrine Disorders 2019 19:39
  23. Early diagnosis and relapse prediction in Graves’ disease influences treatment. We assessed the abilities of four TSH-receptor antibody tests [TRAb] and one cyclic adenosine monophosphate bioassay to predict r...

    Authors: Tristan Struja, Rebecca Jutzi, Noemi Imahorn, Marina Kaeslin, Fabienne Boesiger, Alexander Kutz, Esther Mundwiler, Andreas Huber, Marius Kraenzlin, Beat Mueller, Christian Meier, Luca Bernasconi and Philipp Schuetz
    Citation: BMC Endocrine Disorders 2019 19:38
  24. In the treatment for hypothyroidism, a historically symptom-orientated approach has given way to reliance on a single biochemical parameter, thyroid stimulating hormone (TSH).

    Authors: John E. M. Midgley, Anthony D. Toft, Rolf Larisch, Johannes W. Dietrich and Rudolf Hoermann
    Citation: BMC Endocrine Disorders 2019 19:37
  25. This study aimed to investigate the occurrence and risk factors of thyroid dysfunction (TD) in patients with chronic hepatitis C (CHC) infection in Taiwan.

    Authors: Yu-Kang Chang, Yuan-Tsung Tseng, Kou-Huang Chen and Kow-Tong Chen
    Citation: BMC Endocrine Disorders 2019 19:36
  26. Diabetes mellitus is a growing cause of disease burden globally. Its management is multifaceted, and adherence to pharmacotherapy is known to play a significant role in glycaemic control. Data on medication ad...

    Authors: Leopold Ndemnge Aminde, Maxime Tindong, Calypse A. Ngwasiri, Jeannine A. Aminde, Tsi Njim, Azingala Ajua Fondong and Noah Fongwen Takah
    Citation: BMC Endocrine Disorders 2019 19:35
  27. To compare neurocognitive functioning of Type 1 diabetic mellitus (T1DM) and healthy adults, and explore risk factors of cognitive dysfunction of T1DM patients, especially the association between cognitive imp...

    Authors: Xin Ding, Chen Fang, Xiang Li, Yong-Jun Cao, Qi-Lin Zhang, Yun Huang, Jian Pan and Xia Zhang
    Citation: BMC Endocrine Disorders 2019 19:34
  28. As a member of peroxiredoxin (PRX) family, PRX3 is predominantly located in mitochondria and plays an important role of free radical scavenging. Since a body of evidence demonstrated the involvement of PRX3 in...

    Authors: Hou-Li Liu, Tian-Tian Li, Ai-Qun Yu, Jingmin Li, Xiaoyan Li, Lianqin Li and Tomonori Kaifu
    Citation: BMC Endocrine Disorders 2019 19:32
  29. type 2 diabetes mellitus (T2DM) is a complicated disease that can affect bone health, but the change in bone biochemical markers caused by T2DM was controversial, so the aim of this study was to investigate wh...

    Authors: Lianzi Wang, Tao Li, Jiaqing Liu, Xian Wu, Huihui Wang, Xuemei Li, Enjun Xu, Qiuli Chen, Chuan Yan, Huimin Li, Yuanhong Xu and Wei Wei
    Citation: BMC Endocrine Disorders 2019 19:31
  30. Irregular menstruation is clinically associated with an increased risk for ovarian cancer and disease-related mortality. This relationship remains poorly understood, and a mechanism explaining it has yet to be...

    Authors: Jiao Jiao, Matthew Sagnelli, Bei Shi, Yuanyuan Fang, Ziqi Shen, Tianyu Tang, Bingying Dong, Da Li and Xiuxia Wang
    Citation: BMC Endocrine Disorders 2019 19:30
  31. To determine the relation between daily glycemic fluturation and the intestinal mucosal barrier dysfunction in type 2 diabetes mellitus (T2DM).

    Authors: Lijuan Shen, Li Ao, Haoben Xu, Junfeng Shi, Dali You, Xiuwen Yu, Weixin Xu, Jie Sun and Fei Wang
    Citation: BMC Endocrine Disorders 2019 19:29
  32. Although snoring has been previously reported to be associated with metabolic syndrome (MetS), its interaction with body mass index(BMI) on MetS remains unclear. We aimed to examine the individual effects and ...

    Authors: Yanyan Li, Qian Gao, Lu Li, Yanan Shen, Qing Lu, Jianjun Huang, Chenming Sun, Hui Wang, Nan Qiao, Cong Wang, Haixia Zhang and Tong Wang
    Citation: BMC Endocrine Disorders 2019 19:28
  33. Diabetes-related lower limb amputations (LLA) are associated with significant morbidity and mortality. Although the incidence has decreased over the past two decades in most High-Income Countries, the situatio...

    Authors: Osei Sarfo-Kantanka, Fred Stephen Sarfo, Ishmael Kyei, Charles Agyemang and Jean Claude Mbanya
    Citation: BMC Endocrine Disorders 2019 19:27
  34. Immune checkpoint inhibitors including nivolumab, an anti-programmed cell death protein 1 antibody, are recently developed cancer immunotherapy agents. Immune checkpoint inhibitors are known to cause autoimmun...

    Authors: Ayumu Takeno, Masahiro Yamamoto, Miwa Morita, Sayuri Tanaka, Ippei Kanazawa, Mika Yamauchi, Sakae Kaneko and Toshitsugu Sugimoto
    Citation: BMC Endocrine Disorders 2019 19:25
  35. Data of studies focusing on the trends of adiposity indices among women with prior gestational diabetes mellitus (GDM), are limited and controversial. The aim of this study was to compare overtime trends of ad...

    Authors: Samira Behboudi-Gandevani, Fahimeh Ramezani Tehrani, Maryam Rahmati, Mina Amiri and Fereidoun Azizi
    Citation: BMC Endocrine Disorders 2019 19:24
  36. Dysglycemic status defined by prediabetes and diabetes is known to be related with future risk of diabetic complications and cardiovascular diseases. Herein, we aimed to determine the diagnostic accuracy of gl...

    Authors: Yotsapon Thewjitcharoen, Amia Jones Elizabeth, Siriwan Butadej, Soontaree Nakasatien, Phawinpon Chotwanvirat, Ekgaluck Wanothayaroj, Sirinate Krittiyawong, Tinapa Himathongkam and Thep Himathongkam
    Citation: BMC Endocrine Disorders 2019 19:23
  37. As an insulin-dependent disease, type 1 diabetes requires paying close attention to the glycemic control. Studies have shown that mobile health (mHealth) can improve the management of chronic diseases. However...

    Authors: Xuemei Wang, Wei Shu, Jian Du, Maolin Du, Peiyu Wang, Mingming Xue, Huiqiu Zheng, Yufeng Jiang, Shaohua Yin, Danyan Liang, Ruiqi Wang and Lina Hou
    Citation: BMC Endocrine Disorders 2019 19:21
  38. Measurement of gylcated hemoglobin A1c (HbA1c) plays a central role in monitoring quality of antidiabetic therapy and in the diagnosis of diabetes. Several studies report increased levels of HbA1c in nondiabet...

    Authors: Annette Masuch, Nele Friedrich, Johannes Roth, Matthias Nauck, Ulrich Alfons Müller and Astrid Petersmann
    Citation: BMC Endocrine Disorders 2019 19:20
  39. Sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3) proteins have an important role in counteracting oxidative stress. Although diabetes and hypothyroidism (HT) are both characterized by oxidative stress, the mechanisms a...

    Authors: Abdullah Al-Khaldi and Samar Sultan
    Citation: BMC Endocrine Disorders 2019 19:19
  40. The incretin-based medicines GLP1 analogues (GLP1a) and dipeptidyl peptidase-4 inhibitors (DPP4i) are hypoglycaemic agents licensed for the treatment of type 2 diabetes mellitus (T2DM). Although these drugs po...

    Authors: Giuseppe Roberto, Francesco Barone-Adesi, Francesco Giorgianni, Valeria Pizzimenti, Carmen Ferrajolo, Michele Tari, Claudia Bartolini, Roberto Da Cas, Marina Maggini, Stefania Spila-Alegiani, Paolo Francesconi, Gianluca Trifirò, Elisabetta Poluzzi, Fabio Baccetti and Rosa Gini
    Citation: BMC Endocrine Disorders 2019 19:18
  41. Hypoglycemia presents a barrier to optimum diabetes management and it is related to a negative impact on health-related quality of life, healthcare resource use, and work productivity. Despite the fact that th...

    Authors: Gashayeneh Genetu Tiruneh, Nurilign Abebe and Getenet Dessie
    Citation: BMC Endocrine Disorders 2019 19:17
  42. Renal hyperparathyroidism is a common complication of chronic kidney disease (CKD) or end-stage renal disease (ESRD) characterized by elevated parathyroid hormone levels secondary to derangements in the homeos...

    Authors: Tsai-Sung Tai, Yueh-Han Hsu, Jia Ming Chang and Chien-Chin Chen
    Citation: BMC Endocrine Disorders 2019 19:16

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