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  1. Diabetes self-management education can be helpful for patients with type 2 diabetes in managing their condition. We aimed to study the effects of the group-based PRoactive Interdisciplinary Self-MAnagement (PR...

    Authors: Esther du Pon, Nanne Kleefstra, Frits Cleveringa, Ad van Dooren, Eibert R. Heerdink and Sandra van Dulmen

    Citation: BMC Endocrine Disorders 2019 19:139

    Content type: Research article

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  2. To evaluate the impact of treatment with recombinant human growth hormone (rhGH; Omnitrope®) on the risk of diabetes mellitus in adults with growth hormone deficiency (GHD), using data from the ongoing PATRO A...

    Authors: Paolo Beck-Peccoz, Charlotte Höybye, Robert D. Murray, Suat Simsek, Markus Zabransky, Hichem Zouater and Günter Stalla

    Citation: BMC Endocrine Disorders 2019 19:138

    Content type: Research article

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  3. Body posture may be disordered by vestibular dysfunction, neurological disorders, problems with the distribution of muscle tone, brain injuries, and other dysfunctions. Growth hormone deficiency (GHD) can lead...

    Authors: Magdalena Kobylińska, Roksana Malak, Katarzyna Majewska, Andrzej Kędzia and Włodzimierz Samborski

    Citation: BMC Endocrine Disorders 2019 19:137

    Content type: Research article

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  4. Abdominal obesity and presence of the metabolic syndrome (MetS) significantly increase the risk of developing diseases such as Type 2 diabetes mellitus (T2DM) with escalating emergence of MetS and T2DM constit...

    Authors: Doris Pierce, Lea Merone, Chris Lewis, Tony Rahman, John Croese, Alex Loukas, Malcolm McDonald, Paul Giacomin and Robyn McDermott

    Citation: BMC Endocrine Disorders 2019 19:136

    Content type: Study protocol

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  5. The burden of non-communicable diseases is growing rapidly in low- and middle-income countries. Research suggests that health interventions that aim to improve patient self-management and empower patients to c...

    Authors: Nina Abrahams, Lucy Gilson, Naomi S. Levitt and Joel A. Dave

    Citation: BMC Endocrine Disorders 2019 19:133

    Content type: Research article

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  6. This analysis evaluates the cost-effectiveness of insulin degludec (degludec) versus biosimilar insulin glargine U100 (glargine U100) in patients with type 1 (T1DM) and type 2 diabetes mellitus (T2DM) in Bulga...

    Authors: Monika Russel-Szymczyk, Vasil Valov, Alexandra Savova and Manoela Manova

    Citation: BMC Endocrine Disorders 2019 19:132

    Content type: Research article

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  7. Finding the relationship between the major dietary patterns and cardiometabolic phenotypes could be used for planning prevention programs based on the cultural and dietary habits to prevent transient from a me...

    Authors: Leila Nikniaz, Mahdieh Abbasalizad Farhangi, Jafar Sadegh Tabrizi and Zeinab Nikniaz

    Citation: BMC Endocrine Disorders 2019 19:131

    Content type: Research article

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  8. Abscess in the thyroid gland is a rare but severe infectious disease. The condition can have anatomic or iatrogenic underlying causes. If untreated it could be fatal. Pathogens vary considerably. Treatment is ...

    Authors: Henrik Falhammar, Göran Wallin and Jan Calissendorff

    Citation: BMC Endocrine Disorders 2019 19:130

    Content type: Case report

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  9. Nerves and neurotrophic growth factors are emerging promoters of cancer growth. The precursor for Nerve Growth Factor (proNGF) is overexpressed in thyroid cancer, but its potential role as a clinical biomarker...

    Authors: Christopher W. Rowe, Sam Faulkner, Jonathan W. Paul, Jorge M. Tolosa, Craig Gedye, Cino Bendinelli, Katie Wynne, Shaun McGrath, John Attia, Roger Smith and Hubert Hondermarck

    Citation: BMC Endocrine Disorders 2019 19:128

    Content type: Research article

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  10. We measured the concentrations of the adipocytokines vaspin and visfatin in obese Chinese children. Furthermore, we studied the correlation of these adipocytokines with early-onset metabolic and vascular seque...

    Authors: Chunyan Yin, Wei Hu, Ming Wang and Yanfeng Xiao

    Citation: BMC Endocrine Disorders 2019 19:127

    Content type: Research article

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  11. At present, the proportion of undiagnosed diabetes in Chinese adults is as high as 15.5%. People with diabetes who are not treated and controlled in time may have various complications, such as cardiovascular ...

    Authors: Siyu Liu, Yue Gao, Yuhang Shen, Min Zhang, Jingjing Li and Pinghui Sun

    Citation: BMC Endocrine Disorders 2019 19:126

    Content type: Research article

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  12. Compositional abnormalities in lipoproteins and cardiovascular risk factors play an important role in the progression of diabetic peripheral neuropathy (DPN). This systematic review aimed to estimate the predi...

    Authors: Syed Shah Zaman Haider Naqvi, Saber Imani, Hossein Hosseinifard, Qing-Lian Wen, M. Naveed Shahzad, Iqra Ijaz, Youcai Deng, Man Guo and Yong Xu

    Citation: BMC Endocrine Disorders 2019 19:125

    Content type: Research article

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  13. The present study aimed to investigate the prognostic significance of preoperative main pancreatic duct dilation and the neutrophil-to-lymphocyte ratio (PD-NLR) in pancreatic neuroendocrine tumors (PNETs) of t...

    Authors: Bo Zhou, Canyang Zhan, Jie Xiang, Yuan Ding and Sheng Yan

    Citation: BMC Endocrine Disorders 2019 19:123

    Content type: Research article

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  14. Benign thyroid nodules (BTN) are frequently diagnosed as papillary thyroid carcinoma (PTC), leading to unnecessary treatment. We found that plasma lncRNA DLG1-AS1 was upregulated in PTC patients but not in BTN...

    Authors: Tao He, Huan Wang, Jiangming Sun, Jie Wu, Fakuo Gong, Shujun Li, Hui Wang and Yufeng Li

    Citation: BMC Endocrine Disorders 2019 19:122

    Content type: Research article

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  15. Diabetic ketoacidosis (DKA) is an acute, major, life-threatening complication of diabetes that requires immediate treatment. Allergic reaction to insulin is rare, especially when using recombinant human insuli...

    Authors: Anh Dat Nguyen, Chinh Quoc Luong, Hieu Chi Chu, Van Khoa Dieu Nguyen, Chi Van Nguyen, Tuan Anh Nguyen, Quan Huu Nguyen, Ton Duy Mai, Dinh Van Nguyen, Bay Quang Nguyen, Thong Huu Tran, Phuong Viet Dao, Dat Tuan Nguyen, Nguyet Nhu Nguyen and Son Ngoc Do

    Citation: BMC Endocrine Disorders 2019 19:121

    Content type: Case report

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  16. Agenesis of the dorsal pancreas (ADP) is clinically rare, and it is usually accompanied by abdominal pain. Various disorders of glucose metabolism associating with ADP have been reported, but there are only tw...

    Authors: Tian Yang, Xudan Yang, Luping Wang and Jun Mo

    Citation: BMC Endocrine Disorders 2019 19:120

    Content type: Case report

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  17. The shape of the glucose response curve during an oral glucose tolerance test (OGTT) can predict β-cell function and insulin resistance. However, there have been few studies conducted on Chinese people. Thus, ...

    Authors: Xinqi Cheng, Na Yang, Yuxiu Li, Qi Sun, Ling Qiu, Lingling Xu, Fan Ping, Wei Li and Huabing Zhang

    Citation: BMC Endocrine Disorders 2019 19:119

    Content type: Research article

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  18. Diabetes is 7th largest cause of death worldwide, and prevalence is increasing rapidly in low-and middle-income countries. There is an urgent need to develop and test interventions to prevent and control diabe...

    Authors: Joanna Morrison, Kohenour Akter, Hannah Maria Jennings, Tasmin Nahar, Abdul Kuddus, Sanjit Kumer Shaha, Naveed Ahmed, Carina King, Hassan Haghparast-Bidgoli, Anthony Costello, A. K. Azad Khan, Kishwar Azad and Edward Fottrell

    Citation: BMC Endocrine Disorders 2019 19:118

    Content type: Research article

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  19. Exercise is known to induce multiple beneficial conditioning processes. Conversely, although exercise may generate several hormonal effects, an intrinsic hormonal conditioning process has not been reported. In...

    Authors: Flavio A. Cadegiani and Claudio E. Kater

    Citation: BMC Endocrine Disorders 2019 19:117

    Content type: Research article

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  20. We report a novel mutation within the StAR gene, causing congenital adrenal hyperplasia, with the so far unreported association with heterochromia iridis.

    Authors: Vera Splittstösser, Felix Schreiner, Bettina Gohlke, Maik Welzel, Paul-Martin Holterhus and Joachim Woelfle

    Citation: BMC Endocrine Disorders 2019 19:116

    Content type: Case report

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  21. The prevalence of obesity and its comorbidities, including type 2 diabetes mellitus (T2DM), is dramatically increasing throughout the world; however, the underlying aetiology is incompletely understood. Genome...

    Authors: Naomi L. Cook, Milos Pjanic, Andrew G. Emmerich, Abhiram S. Rao, Susanne Hetty, Joshua W. Knowles, Thomas Quertermous, Casimiro Castillejo-López and Erik Ingelsson

    Citation: BMC Endocrine Disorders 2019 19:115

    Content type: Research article

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  22. Pituitary metastasis is a rare condition with a poor prognosis. Very few patients with pituitary metastasis are symptomatic. It is often associated with presence of co-existing metastases to other organs. Isol...

    Authors: Sirinart Sirinvaravong, Peeradon Vibhatavata, Paweena Chunharojrith, Pornsuk Cheunsuchon and Sutin Sriussadaporn

    Citation: BMC Endocrine Disorders 2019 19:114

    Content type: Case report

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  23. Colorectal cancer (CRC) is the fourth most commonly diagnosed gastrointestinal (GI) malignancy and the third leading cause of cancer-related death worldwide. In the current case-control study, an association b...

    Authors: Ghodratollah Soltani, Arash Poursheikhani, Maryam Yassi, Abdorasool Hayatbakhsh, Matin Kerachian and Mohammad Amin Kerachian

    Citation: BMC Endocrine Disorders 2019 19:113

    Content type: Research article

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  24. Cytologically indeterminate thyroid nodules currently present a challenge for clinical decision-making. The main aim of our study was to determine whether the classifications, American College of Radiology (AC...

    Authors: Thayse Lozovoy Madsen Barbosa, Cleo Otaviano Mesa Junior, Hans Graf, Teresa Cavalvanti, Marcus Adriano Trippia, Ricardo Torres da Silveira Ugino, Gabriel Lucca de Oliveira, Victor Hugo Granella and Gisah Amaral de Carvalho

    Citation: BMC Endocrine Disorders 2019 19:112

    Content type: Research article

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  25. Barakat syndrome is an autosomal dominant rare genetic disease caused by haploinsufficiency of the GATA binding protein 3 (GATA3) gene. It is also known as HDR syndrome, and is characterized by varying degrees of...

    Authors: Anne D. D. Joseph, Nirmala D. Sirisena, Thirunavukarasu Kumanan, Vathualan Sujanitha, Veronika Strelow, Raina Yamamoto, Stefan Wieczorek and Vajira H. W. Dissanayake

    Citation: BMC Endocrine Disorders 2019 19:111

    Content type: Case report

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  26. Severe hypoglycaemia carries a significant risk of morbidity and mortality for people with type 1 diabetes. Economic costs are also high, estimated at approximately £13 million annually in England, UK. Continu...

    Authors: Parizad Avari, Rozana Ramli, Monika Reddy, Nick Oliver and Rachael Fothergill

    Citation: BMC Endocrine Disorders 2019 19:110

    Content type: Study protocol

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  27. Sarcopenia and sarcopenic obesity (SO) have a greater impact on the elderly. This study aimed to explore whether there were sex differences in the prevalence and adverse outcomes of sarcopenia and SO in commun...

    Authors: Yanping Du, Xiaodong Wang, Hua Xie, Songbai Zheng, Xiaoqing Wu, Xiaoying Zhu, Xuemei Zhang, Sihong Xue, Huilin Li, Wei Hong, Wenjing Tang, Minmin Chen, Qun Cheng and Jianqin Sun

    Citation: BMC Endocrine Disorders 2019 19:109

    Content type: Research article

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  28. The adipokine adipsin contributes to insulin resistance (IR), inflammation, and obesity, which are all regarded as high-risk factors for mild cognitive impairment (MCI) in patients with type 2 diabetes mellitu...

    Authors: Dan Guo, Yang Yuan, Rong Huang, Sai Tian, Jiaqi Wang, Hongyan Lin, Ke An, Jin Han and Shaohua Wang

    Citation: BMC Endocrine Disorders 2019 19:108

    Content type: Research article

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  29. Hypoglycemia is a common complication of insulin therapy in patients with Type 1 Diabetes Mellitus (DM). Awareness of hypoglycemic symptoms helps patients to recognize hypoglycemia and initiate self-treatment....

    Authors: Mohammad J. Alkhatatbeh, Nedaa A. Abdalqader and Mohammad A. Y. Alqudah

    Citation: BMC Endocrine Disorders 2019 19:107

    Content type: Research article

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  30. Lifestyle modification targeting weight management is the first-line treatment for women with Polycystic Ovary Syndrome (PCOS) regardless of presenting symptoms. Women with PCOS are more likely to gain more we...

    Authors: Siew Lim, Caroline A. Smith, Michael F. Costello, Freya MacMillan, Lisa Moran and Carolyn Ee

    Citation: BMC Endocrine Disorders 2019 19:106

    Content type: Research article

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  31. Clinical care of patients with cyclic Cushing’s syndrome (CS) is challenging. Classical pitfalls include incorrect subtyping, unnecessary surgical procedures and delayed definite treatment.

    Authors: Adriana Albani, Christina M. Berr, Felix Beuschlein, Marcus Treitl, Klaus Hallfeldt, Jürgen Honegger, Günter Schnauder and Martin Reincke

    Citation: BMC Endocrine Disorders 2019 19:105

    Content type: Case report

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  32. The relationship between breast cancer (BC) and thyroid disease (TD) is still controversial. The aim of the study was to investigate the possible coexistence of TD in patients with newly diagnosed BC and its c...

    Authors: Chiara Dobrinja, Serena Scomersi, Fabiola Giudici, Giulia Vallon, Alessio Lanzaro, Marina Troian, Deborah Bonazza, Andrea Romano, Fabrizio Zanconati, Nicolò de Manzini and Marina Bortul

    Citation: BMC Endocrine Disorders 2019 19:104

    Content type: Research

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  33. Medullary thyroid carcinoma is a malignant uncommon and aggressive tumour of the parafollicular C cells. In about 75% of cases it is sporadic while, in case of RET mutation, it is associated to multiple endocr...

    Authors: Claudio Gambardella, Chiara Offi, Guglielmo Clarizia, Roberto Maria Romano, Immacolata Cozzolino, Marco Montella, Rosa Maria Di Crescenzo, Massimo Mascolo, Angelo Cangiano, Sergio Di Martino, Giancarlo Candela and Giovanni Docimo

    Citation: BMC Endocrine Disorders 2019 19:103

    Content type: Case report

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  34. The relationship between thyroid nodules (TNs) and adiposity is controversial. This paper describes a cross-sectional investigation performed to determine the existence of any such relationship. To assess adip...

    Authors: Hui-xia Yang, Yu Zhong, Wei-hua Lv, Feng Zhang and Hong Yu

    Citation: BMC Endocrine Disorders 2019 19:102

    Content type: Research article

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  35. Diabetes Mellitus is an increasingly prevalent chronic disease characterized by the body’s inability to metabolize glucose. The objective of this study was to build an effective predictive model with high sens...

    Authors: Hang Lai, Huaxiong Huang, Karim Keshavjee, Aziz Guergachi and Xin Gao

    Citation: BMC Endocrine Disorders 2019 19:101

    Content type: Research article

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  36. Abnormal levels of liver enzymes, particularly aminotransferases, are prognostic features of non-alcoholic fatty liver disease (NAFLD). Considering the important role of dietary intakes in development of NAFLD...

    Authors: Parvin Mirmiran, Zahra Gaeini, Zahra Bahadoran and Fereidoun Azizi

    Citation: BMC Endocrine Disorders 2019 19:100

    Content type: Research article

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  37. Glucagon stimulation test (GST) is often employed to assess the insulin reserve of the pancreatic beta cells in diabetic subjects. The clinical significance of the increment of plasma glucose (Δglucose) by exo...

    Authors: Yasutaka Takeda, Yukihiro Fujita, Ryoichi Bessho, Mao Sato, Tomoe Abe, Tsuyoshi Yanagimachi, Hidemitsu Sakagami, Atsuko Abiko, Yumi Takiyama, Tsuguhito Ota and Masakazu Haneda

    Citation: BMC Endocrine Disorders 2019 19:99

    Content type: Research article

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  38. To investigate the prevalence of cardiovascular disease (CVD) risk factors and assess the 10-year risk of CVD in non-menopausal and postmenopausal women with type 2 diabetes mellitus (T2DM).

    Authors: Huanhuan Zhou, Chenghuan Zhang, Jingyu Ni and Xiaoyun Han

    Citation: BMC Endocrine Disorders 2019 19:98

    Content type: Research article

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  39. Charcot neuropathic osteoarthropathy (CNO) is one of the most devastating complications of neuropathy in patients with diabetes. Establishing diagnosis of CNO is difficult, due to the lack of clear clinical an...

    Authors: C. V. Loupa, E. Meimeti, A. Kokas, E. D. Voyatzoglou and A. Donou

    Citation: BMC Endocrine Disorders 2019 19:96

    Content type: Case report

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  40. Cholecystectomy, central obesity, and insulin resistance (IR) are established risk factors for nonalcoholic fatty liver disease (NAFLD). We aimed to examine the relative contributions and combined association ...

    Authors: Wenzhu Yue, Xingxing Sun and Tingting Du

    Citation: BMC Endocrine Disorders 2019 19:95

    Content type: Research article

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  41. Acromegaly is highly associated with thyroid disorders. However, the clinical characteristics of thyroid nodules in individuals with acromegaly who present with thyroid diseases have not been completely elucid...

    Authors: Dianshuang Xu, Bolin Wu, Xiaoju Li, Yunjiu Cheng, Dubo Chen, Yuefeng Fang, Qiu Du, Zhiyong Chen and Xiaodong Wang

    Citation: BMC Endocrine Disorders 2019 19:94

    Content type: Research article

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  42. Obese women with polycystic ovary syndrome (PCOS) may face additional barriers in achieving weight loss. We aimed to compare the effects of the hypocaloric low glycemic index (LGI) diet on anthropometric varia...

    Authors: Farnaz Shishehgar, Parvin Mirmiran, Maryam Rahmati, Maryam Tohidi and Fahimeh Ramezani Tehrani

    Citation: BMC Endocrine Disorders 2019 19:93

    Content type: Research article

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  43. Hypertriglyceridemia is often observed as the result of lipid abnormality and frequently associated with other lipid and metabolic disorders. Aggravation of hypertriglyceridemia is caused by various conditions...

    Authors: Shintaro Irie, Takatoshi Anno, Fumiko Kawasaki, Ryo Shigemoto, Shuhei Nakanishi, Kohei Kaku and Hideaki Kaneto

    Citation: BMC Endocrine Disorders 2019 19:92

    Content type: Case report

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  44. In 2015 approximately 5.0 million people were estimated to have died from diabetes. Poor glycemic control is the most determinant of diabetes-related complication and death. The percentage of patients whose bl...

    Authors: Yitagesu Mamo, Fekede Bekele, Tadesse Nigussie and Ameha Zewudie

    Citation: BMC Endocrine Disorders 2019 19:91

    Content type: Research article

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  45. Endothelial cell-specific molecule-1 (ESM-1) is a biomarker associated with tumor progression in pituitary adenoma. We specifically focused on one type of pituitary adenoma, namely null cell adenoma (NCA) and ...

    Authors: Shousen Wang, Zhifeng Wu, Liangfeng Wei and Jianhe Zhang

    Citation: BMC Endocrine Disorders 2019 19:90

    Content type: Research article

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  46. Diabetes-related kidney disease is associated with end-stage renal disease and mortality, but opportunities remain to quantify its association with cardiovascular and non-cardiovascular morbidity outcomes.

    Authors: James B. Wetmore, Suying Li, Thanh G. N. Ton, Yi Peng, Michael K. Hansen, Cheryl Neslusan, Ralph Riley, Jiannong Liu and David T. Gilbertson

    Citation: BMC Endocrine Disorders 2019 19:89

    Content type: Research article

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  47. Glycosylated hemoglobin (HbA1c) has a detrimental impact on the myocardium with left ventricular (LV) diastolic dysfunction. Obesity is a risk factor of type 2 diabetes. To understand the relationships between...

    Authors: Xin Zuo, Xueting Liu, Runtian Chen, Huiting Ou, Jiabao Lai, Youming Zhang and Dewen Yan

    Citation: BMC Endocrine Disorders 2019 19:88

    Content type: Research article

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