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  1. Type 2 diabetes in the Gulf Cooperation Council countries, including Oman, is currently the fastest growing health crisis and is a significant cause of premature mortality and disability. There is currently in...

    Authors: Adhra Al-Mawali, Ayaman Al-Harrasi, Sathish Kumar Jayapal, Magdi Morsi, Avinash Daniel Pinto, Waleed Al-Shekaili, Hilal Al-Kharusi, Zainab Al-Balushi and John Idikula

    Citation: BMC Endocrine Disorders 2021 21:42

    Content type: Research article

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  2. Gestational diabetes mellitus (GDM) causes many problems for mother and her neonate. A healthy diet plays an important role in preventing GDM. This study aimed to investigate the relationship between major die...

    Authors: Abazar Roustazadeh, Hamed Mir, Sima Jafarirad, Farideh Mogharab, Seyed Ahmad Hosseini, Amir Abdoli and Saiedeh Erfanian

    Citation: BMC Endocrine Disorders 2021 21:41

    Content type: Research article

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  3. Metabolic syndrome (Mets) is prevalent in the general population and has been reported to be an independent risk factor for cognitive impairment. This study aimed to investigate the association of Mets with th...

    Authors: Xiaohui Wang, Long Ji, Zhaoyang Tang, Guoyong Ding, Xueyu Chen, Jian Lv, Yanru Chen and Dong Li

    Citation: BMC Endocrine Disorders 2021 21:40

    Content type: Research article

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  4. Recently, the relationship between thyroid hormones (THs) across the euthyroid ranges and metabolic syndrome (MetS) has been widely discussed. This study aimed to present specific cutoff values of THs to asses...

    Authors: Xi Ding, Chun-Ying Zhu, Rui Li, Li-Ping Wu, Yue Wang, Shi-Qian Hu, Yi-Ming Liu, Feng-Yi Zhao, Yang Zhao, Meng Zhang, Ming-Qian He, Zi-Yi Chen and Bing-Yin Shi

    Citation: BMC Endocrine Disorders 2021 21:39

    Content type: Research article

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  5. The incidence of thyroid nodules is increasing year by year around the world. However, ultrasound is not recommended as a screening test for the general population or patients with a normal thyroid on palpatio...

    Authors: Zhi Chen, Singla Sethiel Mosha, Tong Zhang, Ming Xu, Yanli Li, Zhuoqing Hu, Weiqiang Liang, Xiaoyi Deng, Tingting Ou, Ling Li and Wangen Li

    Citation: BMC Endocrine Disorders 2021 21:38

    Content type: Research article

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  6. This study aimed to develop and validate a nomogram for predicting acute kidney injury (AKI) during the Intensive Care Unit (ICU) stay of patients with diabetic ketoacidosis (DKA).

    Authors: Tingting Fan, Haosheng Wang, Jiaxin Wang, Wenrui Wang, Haifei Guan and Chuan Zhang

    Citation: BMC Endocrine Disorders 2021 21:37

    Content type: Research article

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  7. Transsphenoidal surgery (TSS) to resect an adrenocorticotropic hormone (ACTH)-secreting pituitary adenoma is the first-line treatment for Cushing’s disease (CD), with increasing usage of endoscopic transspheno...

    Authors: Zarina Brady, Aoife Garrahy, Claire Carthy, Michael W. O’Reilly, Christopher J. Thompson, Mark Sherlock, Amar Agha and Mohsen Javadpour

    Citation: BMC Endocrine Disorders 2021 21:36

    Content type: Research article

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  9. Levothyroxine replacement therapy may decrease the risk of adverse pregnancy outcomes among women with subclinical hypothyroidism (SCH). The aim of this study is to conduct a systematic review and meta-analysi...

    Authors: Magnus Bein, Oriana Hoi Yun Yu, Sonia Marzia Grandi, Francesca Y. E. Frati, Ihab Kandil and Kristian B. Filion

    Citation: BMC Endocrine Disorders 2021 21:34

    Content type: Research article

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  10. Immune checkpoint inhibitors (ICIs) are a novel class of oncological agents which are used to treat a number of malignancies. To date seven agents have been approved by the Food and Drug Administration (FDA) t...

    Authors: Christine Newman, Oratile Kgosidalwa, Osamah A. Hakami, Carmel Kennedy, Liam Grogan and Amar Agha

    Citation: BMC Endocrine Disorders 2021 21:33

    Content type: Case report

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  11. Insulin resistance (IR) in skeletal muscle is a key feature of the pre-diabetic state, hypertension, dyslipidemia, cardiovascular diseases and also predicts type 2 diabetes. However, the underlying molecular m...

    Authors: Hemang M. Parikh, Targ Elgzyri, Amra Alibegovic, Natalie Hiscock, Ola Ekström, Karl-Fredrik Eriksson, Allan Vaag, Leif C. Groop, Kristoffer Ström and Ola Hansson

    Citation: BMC Endocrine Disorders 2021 21:32

    Content type: Research article

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  12. Multiple endocrine neoplasia type 1 (MEN1) is a rare inherited syndrome that concurrently involves various endocrine glands. We report a rare case of MEN1 in a 43-year-old man whose first manifestation was an ...

    Authors: Ji Eun Jun, You-Cheol Hwang, Kyu Jeong Ahn, Ho Yeon Chung and In-Kyung Jeong

    Citation: BMC Endocrine Disorders 2021 21:31

    Content type: Case report

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  13. Studies of drug utilization in patients with diabetes, a chronic disease that can be treated with a wide range of available medicines, have attracted substantial social and clinical interest.

    Authors: Artur Mendes Moura, Sofia Oliveira Martins and João Filipe Raposo

    Citation: BMC Endocrine Disorders 2021 21:30

    Content type: Research article

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  14. Cushing’s syndrome occurs due to overproduction of cortisol from adrenal glands. Endogenous hypercortisolemia can occur secondary to adrenocorticotropic hormone (ACTH) dependent as well as independent causes. ...

    Authors: Piyumi Sachindra Alwis Wijewickrama, Vithiya Ratnasamy, Noel P. Somasundaram, Manilka Sumanatilleke and Sathyajith Buddhika Ambawatte

    Citation: BMC Endocrine Disorders 2021 21:29

    Content type: Case report

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  15. Advanced glycation end-products (AGEs) are heterogeneous molecules produced by the non-enzymatic glycation of proteins, lipids, or nucleic acids during hyperglycaemia. Accumulation of AGEs in the peripheral ne...

    Authors: Stella Papachristou, Kalliopi Pafili and Nikolaos Papanas

    Citation: BMC Endocrine Disorders 2021 21:28

    Content type: Review

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  16. Although thyroid function has been demonstrated to be associated with non-alcoholic fatty liver disease (NAFLD) in different population, the prevalence and features of NAFLD in hyperthyroidism have not been re...

    Authors: Bairong Wang, Baomin Wang, Yumei Yang, Jing Xu, Mengyang Hong, Mingfeng Xia, Xiaomu Li and Xin Gao

    Citation: BMC Endocrine Disorders 2021 21:27

    Content type: Research article

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  17. Diabetes Mellitus (DM) is a metabolic disorder associated with acute and chronic complications. Diabetic ketoacidosis (DKA) is the most serious diabetic emergency in patients with type one and type two diabete...

    Authors: Addisu Getie, Adam Wondmieneh, Melaku Bimerew, Getnet Gedefaw and Asmamaw Demis

    Citation: BMC Endocrine Disorders 2021 21:26

    Content type: Research article

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  19. Hyperuricemia is associated with insulin resistance, pancreatic β-cell dysfunction and consequently with development of type 2 diabetes. Although a direct relationship between high levels of uric acid (UA) and...

    Authors: Asghar Ghasemi

    Citation: BMC Endocrine Disorders 2021 21:24

    Content type: Review

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  20. Bullous pemphigoid is the most common bullous chronic autoimmune skin disease. Recent studies have suggested dipeptidyl-peptidase 4 inhibitors as possible predisposing agents of bullous pemphigoid. The objecti...

    Authors: Vaia Lambadiari, Aikaterini Kountouri, Foteini Kousathana, Emmanouil Korakas, Georgios Kokkalis, Sofia Theotokoglou, Lina Palaiodimou, Pelagia Katsimbri, Ignatios Ikonomidis, Konstantinos Theodoropoulos and Evangelia Papadavid

    Citation: BMC Endocrine Disorders 2021 21:23

    Content type: Research article

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  21. Adrenal vein sampling (AVS) is the preferred method for subtyping patients with primary aldosteronism, while the procedure is technically challenging. This study evaluated the feasibility and effectiveness of ...

    Authors: Jindong Wan, Fei Ran, Siwei Xia, Jixin Hou, Dan Wang, Sen Liu, Yi Yang, Peng Zhou and Peijian Wang

    Citation: BMC Endocrine Disorders 2021 21:22

    Content type: Research article

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  22. Previous studies have indicated inconsistent relationships of diabetes with thyroid cancer risk, yet little is known in China. In this study, we aimed to investigate the associations between diabetes, diabetes...

    Authors: Meng Wang, Wei-Wei Gong, Feng Lu, Ru-Ying Hu, Qing-Fang He and Min Yu

    Citation: BMC Endocrine Disorders 2021 21:21

    Content type: Research article

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  23. Familial hypocalciuric hypercalcemia (FHH) is a heterogeneous autosomal-dominant disorder of calcium hemostasis that may be difficult to distinguish clinically from mild primary hyperparathyroidism. Loss-of-fu...

    Authors: Noha N Mukhtar, Mohei El-Din M Abouzied, Mohammed H Alqahtani and Muhammad M Hammami

    Citation: BMC Endocrine Disorders 2021 21:20

    Content type: Case report

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  24. The present study aimed to evaluate the effect of artesunate (ART) on the reduction of cardiovascular complications in a type 1 diabetes model and to investigate the associated mechanism based on the receptor ...

    Authors: Yi Chen, Wei Li, Xiaolin Nong, Chen Liang, Jiaquan Li, Wei Lu, Bingge Wang, Zhong Yuan and Shiying Yang

    Citation: BMC Endocrine Disorders 2021 21:19

    Content type: Research article

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  25. Currently, there is a lack of data relating to glycemic parameters and their relationship with C-peptide (CP) and proinsulin (PI) during the partial remission period (PRP) in type 1 diabetes mellitus (T1D). Th...

    Authors: Gül Yeşiltepe-Mutlu, Merve Çapacı, Ecem Can, Tuğba Gökçe, Gizem Bayrakçı, Serra Muradoğlu, Said İncir, Esra Papatya Çakır and Şükrü Hatun

    Citation: BMC Endocrine Disorders 2021 21:18

    Content type: Research article

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  26. Diabetic retinopathy is the most common microvascular complication of diabetes and it is a leading cause of visual impairment and blindness among patients with diabetes. This study aimed to investigate the eff...

    Authors: Seyed Shahriar Hosseini, Mohsen Shamsi, Mahboobeh Khorsandi and Rahmatollah Moradzadeh

    Citation: BMC Endocrine Disorders 2021 21:17

    Content type: Research article

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  27. Long-term antithyroid drug therapy has become one of the options for treatment of Graves’ hyperthyroidism. The aim of this study was to compare thyroid status in those who discontinued methimazole (MMI) treatm...

    Authors: Fereidoun Azizi, Hengameh Abdi and Atieh Amouzegar

    Citation: BMC Endocrine Disorders 2021 21:16

    Content type: Research article

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  28. Functional gonadotroph adenomas (FGAs) are rare adenomas that most commonly secrete FSH. However, solitary LH-secreting pituitary adenomas are unusual.

    Authors: Yi Zhang, Cheng Chen, Min Lin, Kan Deng, Huijuan Zhu, Wenbin Ma, Hui Pan, Renzhi Wang and Yong Yao

    Citation: BMC Endocrine Disorders 2021 21:15

    Content type: Case report

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  29. Skin autofluorescence (SAF) is a non-invasive marker of tissue accumulation of advanced glycation endproducts (AGE). Recently, we demonstrated in the general population that elevated SAF levels predict the dev...

    Authors: Henderikus E. Boersma, Robert P. van Waateringe, Melanie M. van der Klauw, Reindert Graaff, Andrew D. Paterson, Andries J. Smit and Bruce H. R. Wolffenbuttel

    Citation: BMC Endocrine Disorders 2021 21:14

    Content type: Research article

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  30. Primary central nervous system lymphoma is a rare extra-nodal lymphoma of the central nervous system. Primary central nervous system lymphoma lesions usually appear in the vicinity of the ventricle, and there ...

    Authors: Ken Takao, Ayaka Tani, Tetsuya Suwa, Yayoi Kuwabara-Ohmura, Kenta Nonomura, Yanyan Liu, Takehiro Kato, Masami Mizuno, Takuo Hirota, Mayumi Enya, Katsumi Iizuka, Yukio Horikawa, Chiemi Saigo, Yusuke Kito, Tatsuhiko Miyazaki, Naoyuki Ohe…

    Citation: BMC Endocrine Disorders 2021 21:13

    Content type: Case report

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  31. Pseudohypoparathyroidism is a rare genetic disease characterized by hypocalcaemia and hyperphosphataemia due to the defect to the guanine nucleotide-binding protein alpha subunit (GNAS) gene. Patients with pse...

    Authors: Difei Lu, Aimei Dong, Junqing Zhang and Xiaohui Guo

    Citation: BMC Endocrine Disorders 2021 21:12

    Content type: Case report

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  32. Endogenous Cushing’s syndrome (CS) results in increased cardiovascular (CV) morbidity and mortality. So far, most studies focussed on distinct disease entities rather than the integrity of the CV system. We he...

    Authors: Kristina Ehrlich, Caroline Morbach, Theresa Reiter, Peter Ulrich Heuschmann, Anke Hannemann, Martin Fassnacht, Stefan Störk, Stefanie Hahner and Timo Deutschbein

    Citation: BMC Endocrine Disorders 2021 21:11

    Content type: Study protocol

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  33. Weight loss therapy is becoming more and more important, and two classes of molecules, namely amylin receptor and GLP-1 receptor agonists, have shown promise in this regard. Interestingly, these molecules have...

    Authors: Anna Thorsø Larsen, Sofie Gydesen, Nina Sonne, Morten Asser Karsdal and Kim Henriksen

    Citation: BMC Endocrine Disorders 2021 21:10

    Content type: Research article

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  34. Neuroendocrine tumor (NET) with adrenocorticotropic hormone (ACTH) secretion are very rare. To our knowledge, no follow-up study is published for ACTH-secreting NET, regardless of the primary site, to show sec...

    Authors: Fatemeh Rahmani, Maryam Tohidi, Maryam Dehghani, Behrooz Broumand and Farzad Hadaegh

    Citation: BMC Endocrine Disorders 2021 21:9

    Content type: Case report

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  35. Studies analyzing the association between parity and normal-weight metabolic syndrome (MetS) in postmenopausal women of normal weight remain limited, this study aimed to explore the association between parity ...

    Authors: Mengte Shi, Xinhe Zhou, Chao Zheng and Youjin Pan

    Citation: BMC Endocrine Disorders 2021 21:8

    Content type: Research article

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  36. Red cell distribution width (RDW) is a predicter of infections, cancer and diabetes. However, the relationship between RDW and β-cell function and insulin resistance remains unclear in patients with type 2 dia...

    Authors: Deyuan Zhang, Siqi Zhang, Lifang Wang, Tianrong Pan and Xing Zhong

    Citation: BMC Endocrine Disorders 2021 21:7

    Content type: Research article

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  37. Neuroendocrine tumors (NETs) are rare tumors harboring overexpression of somatostatin receptors (SSTRs) on their cell membrane. Because some organs, such as the spleen, adrenal glands and liver, physiologicall...

    Authors: Emre Gezer, Berrin Çetinarslan, Dilek Karakaya, Zeynep Cantürk, Alev Selek, Mehmet Sözen and Serkan İşgören

    Citation: BMC Endocrine Disorders 2021 21:6

    Content type: Case report

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  38. Multiple pathological manifestations are rarely present in patients with primary hyperparathyroidism (PHPT). Here we described a case of a young woman who presented with multiple skeletal destructions and rece...

    Authors: Shuai Lu, Maoqi Gong, Yejun Zha, Aimin Cui, Wei Tian and Xieyuan Jiang

    Citation: BMC Endocrine Disorders 2021 21:5

    Content type: Case report

    Published on:

  39. Hypercalcemia of malignancy is relatively common in several cancers. However, in colorectal cancer, paraneoplastic phenomena that cause hypercalcemia is uncommon. In the few cases that are reported, secretion ...

    Authors: Vegard Heimly Brun, Erik Knutsen, Helge Stenvold and Hanne Halvorsen

    Citation: BMC Endocrine Disorders 2021 21:4

    Content type: Case report

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  40. The common endocrine disorder primary hyperparathyroidism (PHPT) can be cured by surgery. Preoperative localization of parathyroid adenoma (PTA) by imaging is a prerequisite for outpatient minimally invasive p...

    Authors: Elske Quak, Audrey Lasne Cardon, Renaud Ciappuccini, Charline Lasnon, Vianney Bastit, Véronique Le Henaff, Barbara Lireux, Gauthier Foucras, Cyril Jaudet, Celia Berchi, Jean-Michel Grellard, Justine Lequesne, Bénédicte Clarisse and Stéphane Bardet

    Citation: BMC Endocrine Disorders 2021 21:3

    Content type: Study protocol

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  41. Noonan syndrome is an inherited disease involving multiple systems. More than 15 related genes have been discovered, among which LZTR1 was discovered recently. However, the pathogenesis and inheritance pattern of...

    Authors: Xiu Zhao, Zhuoguang Li, Li Wang, Zhangzhang Lan, Feifei Lin, Wenyong Zhang and Zhe Su

    Citation: BMC Endocrine Disorders 2021 21:2

    Content type: Case report

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  42. Serum uric acid (SUA) is associated with the development of diabetic kidney disease (DKD). Thyroid hormones can regulate metabolism and insulin resistance. The relationship between SUA and thyroid function in ...

    Authors: Xiaomeng Feng, Jing Huang, Yan Peng and Yuan Xu

    Citation: BMC Endocrine Disorders 2021 21:1

    Content type: Research article

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  43. Thyroid associated orbitopathy (TAO) is the most common extrathyroidal complication of Graves’ disease. The disease course ranges from mild, where symptomatic therapy is sufficient, to severe, where high dose ...

    Authors: Janos K. Aranyosi, Tamas Deli, Annamaria Erdei, Geza Toth, Attila Jakab, Mariann Fodor, Endre V. Nagy and Bernadett Ujhelyi

    Citation: BMC Endocrine Disorders 2020 20:183

    Content type: Case report

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  44. Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) are the two most common hyperglycemic emergencies (HEs) associated with diabetes mellitus. Individuals with HEs can present with combined ...

    Authors: Xiao-yan Wu, Dun-min She, Fang Wang, Gang Guo, Ran Li, Ping Fang, Ling Li, Yun Zhou, Ke-qin Zhang and Ying Xue

    Citation: BMC Endocrine Disorders 2020 20:182

    Content type: Research article

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  45. To evaluate the association between diet and disease, the consideration of a whole diet has appeared to be more effective than the examination of single-nutrient intake. This study aimed to examine the relatio...

    Authors: Sahar Golpour-Hamedani, Nahid Rafie, Makan Pourmasoumi, Parvane Saneei and Sayyed Morteza Safavi

    Citation: BMC Endocrine Disorders 2020 20:181

    Content type: Research article

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  46. Existing prevention and treatment strategies target the classic types of diabetes yet this approach might not always be appropriate in some settings where atypical phenotypes exist. This study aims to assess t...

    Authors: Charlotte M. Bavuma, Sanctus Musafiri, Pierre-Claver Rutayisire, Loise M. Ng’ang’a, Ruth McQuillan and Sarah H. Wild

    Citation: BMC Endocrine Disorders 2020 20:180

    Content type: Research article

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  47. Lipid accumulation product (LAP) is a new index based on a combination of waist circumference (WC) and serum triglycerides (TG) reflecting lipid accumulation. In this cross-sectional study, we aimed to explore...

    Authors: Lianqin Dong, Mingzhu Lin, Wengui Wang, Danyan Ma, Yun Chen, Weijuan Su, Zheng Chen, Shunhua Wang, Xuejun Li, Zhibin Li and Changqin Liu

    Citation: BMC Endocrine Disorders 2020 20:179

    Content type: Research article

    Published on:

  48. Circulating angiopoietin-like 2 (ANGPTL2) protein levels are known to be significantly increased in numerous chronic inflammatory diseases and are associated with the diagnosis and/or prognosis of cardiovascular ...

    Authors: Yan Wang, Zhaohui Zheng, Yuxian Yang, Jianan Lang, Ning Zhang, Longyan Yang and Dong Zhao

    Citation: BMC Endocrine Disorders 2020 20:178

    Content type: Research article

    Published on:

  49. Plasma aldosterone-to-renin ratio (ARR) is popularly used for screening primary aldosteronism (PA). Some medications, including diuretics, are known to have an effect on ARR and cause false-negative and false-...

    Authors: Toshitaka Sawamura, Shigehiro Karashima, Satoshi Nagase, Hidetaka Nambo, Eiko Shimizu, Takuya Higashitani, Daisuke Aono, Azusa Ohbatake, Mitsuhiro Kometani, Masashi Demura, Kenji Furukawa, Yoshiyu Takeda and Takashi Yoneda

    Citation: BMC Endocrine Disorders 2020 20:177

    Content type: Research article

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  50. Thyroid associated orbitopathy (TAO) is defined as an immune mediated inflammatory process affecting the extraocular muscles, connective and adipose tissue of uncertain etiopathogenesis. TAO are classically de...

    Authors: Radwan El Othman, Christelle Ephrem, Elsie Touma, Souheil Hallit and Rola El Othman

    Citation: BMC Endocrine Disorders 2020 20:176

    Content type: Case report

    Published on:

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