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  1. We investigated the changes in blood glucose fluctuation, gastric emptying, and vascular endothelial function by switching from an exenatide twice-daily formulation (BID) to a once-weekly formulation (QW) sinc...

    Authors: Jun Inaishi, Yoshifumi Saisho, Yuusuke Watanabe, Tami Tsuchiya, Hironobu Sasaki, Tatsuhiro Masaoka and Hiroshi Itoh
    Citation: BMC Endocrine Disorders 2022 22:20
  2. Participants’ study satisfaction is important for both compliance with study protocols and retention, but research on parent study satisfaction is rare. This study sought to identify factors associated with pa...

    Authors: Jessica Melin, Kristian F. Lynch, Markus Lundgren, Carin Andrén Aronsson, Helena Elding Larsson and Suzanne Bennett Johnson
    Citation: BMC Endocrine Disorders 2022 22:19
  3. The alarming rise in the worldwide prevalence of obesity and associated type 2 diabetes mellitus (T2DM) have reached epidemic portions. Diabetes in its many forms and T2DM have different physiological backgrou...

    Authors: Nasser Sakran, Yitka Graham, Tadeja Pintar, Wah Yang, Radwan Kassir, Edith M. Willigendael, Rishi Singhal, Zoë E. Kooreman, Dharmanand Ramnarain, Kamal Mahawar, Chetan Parmar, Brijesh Madhok and Sjaak Pouwels
    Citation: BMC Endocrine Disorders 2022 22:9
  4. More than three decades of research and study for overcoming the problem of “non-acceptance/non-compliance” of patients has neither resolved nor reduced the severity of this problem. This phenomenological stud...

    Authors: Monire Davoodi, Behnaz Dindamal, Hossein Dargahi and Farzad Faraji-Khiavi
    Citation: BMC Endocrine Disorders 2022 22:18
  5. Although there is some evidence that vitamin D deficiency is highly prevalent in the Middle East, however its health impact is still not clear. The aim of this study was to assess the prevalence, causes and he...

    Authors: Salah Gariballa, Javed Yasin, Ghada Abluwi and Awad Al Essa
    Citation: BMC Endocrine Disorders 2022 22:17
  6. Patients with primary hyperparathyroidism (pHPT) and impaired kidney function (estimated glomerular filtration rate (eGFR) < 60 mL/min) are offered parathyroidectomy (PTX) to protect them from further complica...

    Authors: Josephine Matzen, Lise Sofie Bislev, Tanja Sikjær, Lars Rolighed, Mette Friberg Hitz, Pia Eiken, Anne Pernille Hermann, Jens-Erik Beck Jensen, Bo Abrahamsen and Lars Rejnmark
    Citation: BMC Endocrine Disorders 2022 22:14
  7. Research regarding the association between severe obesity and in-hospital mortality is inconsistent. We evaluated the impact of body mass index (BMI) levels on mortality in the medical wards. The analysis was ...

    Authors: Shelly Soffer, Eyal Zimlichman, Benjamin S. Glicksberg, Orly Efros, Matthew A. Levin, Robert Freeman, David L. Reich and Eyal Klang
    Citation: BMC Endocrine Disorders 2022 22:13
  8. The aim of this study was to determine the differences in biochemical parameters and diabetic ketoacidosis (DKA) severity in adult patients with type 1 and type 2 diabetes and utilization of serum BHB as a bio...

    Authors: Atchara Charoenpiriya, Laor Chailurkit and Boonsong Ongphiphadhanakul
    Citation: BMC Endocrine Disorders 2022 22:7
  9. Whether Hashimoto’s thyroiditis (HT) affects the lymph node metastasis of papillary thyroid carcinoma (PTC) remains uncertain. The diagnostic criteria for HT differed in previous studies. Our study focused on ...

    Authors: Lirong Wang, Jiawen Chen, Xin Yuan, Juan Wang, Lei Sun, Jue Jiang, Lin Zhang, Min Liu and Qi Zhou
    Citation: BMC Endocrine Disorders 2022 22:12
  10. Primary macronodular adrenal hyperplasia (PMAH), previously termed ACTH-independent macronodular adrenal hyperplasia (AIMAH), is a rare cause of Cushing’s syndrome usually characterized by functioning adrenal ...

    Authors: Xiao-Gang Tan, Jie Zhu and Liang Cui
    Citation: BMC Endocrine Disorders 2022 22:11
  11. Glucocorticoid (GC)-induced hyperglycemia is a frequent adverse effect in hospitalized patients. Guidelines recommend insulin treatment to a target range of 6–10 mmol/L (108–180 mg/dl), but efficacies of parti...

    Authors: Franzisca Merkofer, Tristan Struja, Neele Delfs, Carlos C. Spagnuolo, Jason F. Hafner, Kevin Kupferschmid, Ciril Baechli, Philipp Schuetz, Beat Mueller and Claudine A. Blum
    Citation: BMC Endocrine Disorders 2022 22:8
  12. Studies have shown that the high incidence of type 2 diabetes in China is associated with low birth weight and excessive nutrition in adulthood, which occurred during the famine years of the 1950s and 1960s, t...

    Authors: Jing Liu, Hang Zhao, Linlin Yang, Xing Wang, Linquan Yang, Yuling Xing, Xiuqin Lv, Huijuan Ma and Guangyao Song
    Citation: BMC Endocrine Disorders 2022 22:10
  13. Prophylactic central lymph node dissection (PCND) was a basic consensus for patients with papillary thyroid carcinoma (PTC) in China. However, unilateral or bilateral central lymph node dissection (CND) was st...

    Authors: Shouyi Yan, Jiafan Yu, Wenxin Zhao, Bo Wang and Liyong Zhang
    Citation: BMC Endocrine Disorders 2022 22:5
  14. Reduced skeletal muscle has been suggested as a potential risk factor for type 2 diabetes mellitus (T2DM). Serum creatinine is the primary metabolite of creatine in skeletal muscle. Therefore, low serum creati...

    Authors: Do Kyeong Song, Young Sun Hong, Yeon-Ah Sung and Hyejin Lee
    Citation: BMC Endocrine Disorders 2022 22:4
  15. Immune responses, especially type 2 immunity, might be related to the prevalence of thyroid nodules, while the key regulators and potential pathways are remaining largely unknown. In addition, the immune statu...

    Authors: Sanxing Wang, Xia Wang, Xiang Hua, Shichao Jiang, Yong Xie and Hongying Liu
    Citation: BMC Endocrine Disorders 2022 22:2
  16. Pituitary adenomas impose a burden of morbidity on patients and characterizing the molecular mechanisms underlying its pathogenesis received remarkable attention. Despite the appealing role of necroptosis as a...

    Authors: Mohammad E. Khamseh, Alireza Sheikhi, Zahra Shahsavari, Mohammad Ghorbani, Hamideh Akbari, Mehrnaz Imani, Mahshid Panahi, Alimohammad Alimohammadi, Maryam Ameri, Shima Nazem, Vahid Salimi and Masoumeh Tavakoli-Yaraki
    Citation: BMC Endocrine Disorders 2022 22:1
  17. The relationship between sleep duration and anthropometric indices are still unclear. This study aimed to explore the association between sleep duration and body mass index (BMI), percentage of body fat (PBF) ...

    Authors: Yaqi Fan, Li Zhang, Yuxue Wang, Chunjun Li, Binbin Zhang, Jiangshan He, Pei Guo, Xin Qi, Mianzhi Zhang, Congfang Guo, Yirui Guo and Minying Zhang
    Citation: BMC Endocrine Disorders 2021 21:247
  18. Oxidative Stress, an imbalance in the pro-oxidant/antioxidant homeostasis, occurs in many physiological and non-physiological processes and several human diseases, including diabetes mellitus (DM) and glucose-...

    Authors: Naif S. Karadsheh, Nisreen A. Quttaineh, Salem N. Karadsheh and Mohammad El-Khateeb
    Citation: BMC Endocrine Disorders 2021 21:246
  19. Polyethylene glycol loxenatide (PEX-168) is a new antidiabetic drug; as such, there are not yet any reports on its weight loss effect. Therefore, this trial was designed to investigate the effect of PEX-168 on...

    Authors: Zeyuan Guo, Yuting Wu, Lihua Zhu, Yong Wang, Daorong Wang and Xiaofang Sun
    Citation: BMC Endocrine Disorders 2021 21:245
  20. Normal-weight maintenance hemodialysis (MHD) patients with abdominal obesity exhibited a more proatherogenic profile than overweight and obesity patients with abdominal obesity, highlighting the importance of ...

    Authors: Chaomin Zhou, Yanzhe Peng, Wenyong Jiang, Jing Yuan and Yan Zha
    Citation: BMC Endocrine Disorders 2021 21:244
  21. Short stature is the most consistent characteristic feature of Turner syndrome (TS). To improve final heights of children with TS effectively, it is important to provide them with early and appropriate treatme...

    Authors: Jinsup Kim, Min-Sun Kim, Byung-Kyu Suh, Cheol Woo Ko, Kee-Hyoung Lee, Han-Wook Yoo, Choong Ho Shin, Jin Soon Hwang, Ho-Seong Kim, Woo Yeong Chung, Chan Jong Kim, Heon-Seok Han and Dong-Kyu Jin
    Citation: BMC Endocrine Disorders 2021 21:243
  22. Different inflammatory and immune cytokines play a key role in the development of cirrhosis of liver (CL). To investigate the association between interleukin-6,10 (IL-6,10) genes polymorphisms and CL risk thro...

    Authors: Minghui Zheng, Weizhen Fang, Menglei Yu, Rui Ding, Hua Zeng, Yan Huang, Yuanyang Mi and Chaohui Duan
    Citation: BMC Endocrine Disorders 2021 21:242
  23. This study aimed to explore the associations of thyroid hormones with body fat content and lipid metabolism in euthyroid male patients with type 2 diabetes mellitus (T2DM).

    Authors: Xia Sun, Liping Chen, Rongzhen Wu, Dan Zhang and Yinhui He
    Citation: BMC Endocrine Disorders 2021 21:241
  24. Pentraxin 3 (PTX3) - a crucial humoral innate immunity component – is related to obesity and cardiovascular complications in women who suffer from polycystic ovary syndrome (PCOS). However, the circulating PTX...

    Authors: Congcong Jin, Kexin Zou, Yue Xu, Haiyan Yang and Jiexue Pan
    Citation: BMC Endocrine Disorders 2021 21:240
  25. We aimed to investigate the clinical characteristics and islet β-cell function in patients with Klinefelter syndrome (KS) and hyperglycemia.

    Authors: Shixuan Liu, Tao Yuan, Shuoning Song, Shi Chen, Linjie Wang, Yong Fu, Yingyue Dong, Yan Tang and Weigang Zhao
    Citation: BMC Endocrine Disorders 2021 21:239
  26. Graves’ disease (GD) is one of the most common autoimmune thyroid diseases (AITDs) in humans, and thyrotropin receptor antibody (TRAb) is a characterized autoantibody in GD. The use of radioactive iodine thera...

    Authors: Ya Fang, Wen-Hua Du, Cao-Xu Zhang, Shuang-Xia Zhao, Huai-Dong Song, Guan-Qi Gao and Mei Dong
    Citation: BMC Endocrine Disorders 2021 21:238
  27. Our study aims to summarize the clinical characteristics of rare types of congenital adrenal hyperplasia (CAH) other than 21-hydroxylase deficiency (21-OHD), and to explore the clinical applications of genetic...

    Authors: Zhuoguang Li, Yan Liang, Caiqi Du, Xiao Yu, Ling Hou, Wei Wu, Yanqing Ying and Xiaoping Luo
    Citation: BMC Endocrine Disorders 2021 21:237
  28. Prolactinoma is a functional pituitary adenoma that secretes excessive prolactin. Dopamine agonists (DAs) such as bromocriptine (BRC) are the first-line treatment for prolactinomas, but the resistance rate is ...

    Authors: Shuman Wang, Aihua Wang, Yu Zhang, Kejing Zhu, Xiong Wang, Yonggang Chen and Jinhu Wu
    Citation: BMC Endocrine Disorders 2021 21:235
  29. Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder affecting up to 13 % of women. Lifestyle interventions are first-line treatments, however attrition in women with PCOS is high. This review summa...

    Authors: Carolyn Ee, Stephanie Pirotta, Aya Mousa, Lisa Moran and Siew Lim
    Citation: BMC Endocrine Disorders 2021 21:234
  30. A number of studies have identified patient-, provider-, and community-level barriers to effective diabetes management among South Asian Americans, who have a high prevalence of type 2 diabetes. However, no mu...

    Authors: Sahnah Lim, Laura C. Wyatt, Shinu Mammen, Jennifer M. Zanowiak, Sadia Mohaimin, Andrea B. Troxel, Stacy Tessler Lindau, Heather T. Gold, Donna Shelley, Chau Trinh-Shevrin and Nadia S. Islam
    Citation: BMC Endocrine Disorders 2021 21:233
  31. The PARADIGHM registry of adult and pediatric patients with chronic hypoparathyroidism evaluates the long-term safety and effectiveness of treatment with recombinant human parathyroid hormone, rhPTH(1-84), and...

    Authors: Neil Gittoes, Lars Rejnmark, Steven W. Ing, Maria Luisa Brandi, Sigridur Björnsdottir, Stefanie Hahner, Lorenz C. Hofbauer, Pascal Houillier, Aliya A. Khan, Michael A. Levine, Michael Mannstadt, Dolores M. Shoback, Tamara J. Vokes, Pinggao Zhang, Claudio Marelli, John Germak…
    Citation: BMC Endocrine Disorders 2021 21:232
  32. Nonalcoholic fatty liver disease (NAFLD) and gallstone disease (GSD) often coexist in the general population owing to shared risk factors. This study explored the relationship between NAFLD and GSD in patients...

    Authors: Ye Lu, Lili Hu, Jing Song, Jing Wan, Haibing Chen and Jun Yin
    Citation: BMC Endocrine Disorders 2021 21:231
  33. Myxedema coma, which occurs due to hypothyroidism, is a rare and life-threatening condition. Some patients have hemodynamic dysfunction, which consequently leads to cardiac arrest. The rarity of this condition...

    Authors: Asami Yoshinaka, Masayuki Akatsuka, Shuji Yamamoto and Michiaki Yamakage
    Citation: BMC Endocrine Disorders 2021 21:229
  34. The outbreak of severe acute respiratory syndrome novel coronavirus 2 (SARS-CoV-2) has spread rapidly worldwide. SARS-CoV-2 has been found to cause multiple organ damage; however, little attention has been pai...

    Authors: Juan Zheng, Zhenhai Cui, Ningjie Shi, Shenghua Tian, Ting Chen, Xueyu Zhong, Kangli Qiu, Jiaoyue Zhang, Tianshu Zeng, Lulu Chen and Huiqing Li
    Citation: BMC Endocrine Disorders 2021 21:228
  35. Although there is a strong association between obesity and obstructive sleep apnoea (OSA), the effects of OSA and CPAP therapy on weight loss are less well known. The aim of this study in adults with class 3 o...

    Authors: Sophie Kobuch, Fiona Tsang, Ritesh Chimoriya, Daniel Gossayn, Sarah O’Brien, Javeria Jamal, Leon Laks, Abd Tahrani, Nic Kormas and Milan K Piya
    Citation: BMC Endocrine Disorders 2021 21:227
  36. Quantitatively staging TAO using MRI remains limited. Our study aims to identify the cut-off signal intensity value for staging TAO using STIR sequence scan.

    Authors: Qian Ge, Xiaohui Zhang, Lu Wang, Yao Fan, Qian Huang, Ning Yao, Jian Long and Chun Liu
    Citation: BMC Endocrine Disorders 2021 21:226
  37. Prolactinoma is the major cause of hyperprolactinemia, and dopamine agonists (DAs) are generally the first-line treatment for them. Several studies have reviewed the recurrent rate of hyperprolactinemia after ...

    Authors: Yunzhi Zou, Depei Li, Jiayu Gu, Siyu Chen, Xia Wen, Jiajun Dong and Xiaobing Jiang
    Citation: BMC Endocrine Disorders 2021 21:225
  38. Many smaller studies have previously shown a significant association between thyroid autoantibody induced hypothyroidism and lower serum vitamin D levels. However, these finding have not been confirmed by larg...

    Authors: Sandeep Appunni, Muni Rubens, Venkataraghavan Ramamoorthy, Anshul Saxena, Raees Tonse, Emir Veledar and Peter McGranaghan
    Citation: BMC Endocrine Disorders 2021 21:224
  39. Maturity Onset Diabetes of the Young (MODY) is an autosomal dominant type of diabetes. Pathogenic variants in fourteen genes are reported as causes of MODY. Its symptoms overlap with type 1 and type 2 diabetes...

    Authors: Ibrar Rafique, Asif Mir, Muhammad Arif Nadeem Saqib, Muhammad Naeem, Luc Marchand and Constantin Polychronakos
    Citation: BMC Endocrine Disorders 2021 21:223
  40. Self-monitoring of blood glucose (SMBG) has been shown to reduce hemoglobin A1C (HbA1C). Accordingly, guidelines recommend SMBG up to 4–10 times daily for adults with type 2 diabetes (T2DM) on insulin. For per...

    Authors: Alex R. Montero, David Toro-Tobon, Kelly Gann, Carine M. Nassar, Gretchen A. Youssef and Michelle F. Magee
    Citation: BMC Endocrine Disorders 2021 21:222
  41. The term non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) was recently proposed as a non-malignant thyroid lesion with indolent behavior that does not require post-operativ...

    Authors: Yasaman Fakhar, Alireza Khooei, Atena Aghaee, Hadis Mohammadzadeh Kosari, Leonard Wartofsky and Seyed Rasoul Zakavi
    Citation: BMC Endocrine Disorders 2021 21:221
  42. Primary hyperparathyroidism (PHPT) and familial hypocalciuric hypercalcemia (FHH) are the most important differential diagnosis of parathyroid hormone (PTH)-dependent hypercalcemia. The clinical features of FH...

    Authors: Maryam Zahedi, Reyhane Hizomi Arani, Maryam Rafati, Atieh Amouzegar and Farzad Hadaegh
    Citation: BMC Endocrine Disorders 2021 21:220
  43. Accumulating evidence indicates that vitamin D deficiency has been increased globally over the last two decades. However, the majority of these studies are concerned with cities and there is scant information ...

    Authors: Maryam Marzban, Mohammadreza Kalantarhormozi, Mehdi Mahmudpour, Afshin Ostovar, Saeed Keshmiri, Amir Hossein Darabi, Abdolmohammad Khajeian, Amirreza Bolkheir, Azam Amini and Iraj Nabipour
    Citation: BMC Endocrine Disorders 2021 21:219
  44. The study aimed to evaluate whether the presence of DKA at diabetes diagnosis was associated with poorer metabolic control during a 5-year follow-up.

    Authors: Kowalczyk Emilia, Stypułkowska Aneta, Majewska Barbara, Jarzębowska Małgorzata, Hoffmann Aleksandra, Buła Paulina and Szypowska Agnieszka
    Citation: BMC Endocrine Disorders 2021 21:218
  45. Aging reduces the quality and strength of bones and muscles and increases body fat, which can lead to the simultaneous occurrence of sarcopenia, osteopenia, and adiposity, a condition referred to as OsteoSarco...

    Authors: Yu-Hsiang Su, Yu-Ming Chang, Chih-Ying Kung, Chiu-Kuei Sung, Wei-Shin Foo, Mei-Hua Wu and Shang-Jyh Chiou
    Citation: BMC Endocrine Disorders 2021 21:216

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