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  1. Acarbose slows down the intestinal absorption of carbohydrates, but its effects on the secretion of incretins are still poorly known. This study aimed to examine the effects of single-dose acarbose on the secr...

    Authors: Zhong Chen, Xiaoying Fu, Jian Kuang, Ju Chen, Hongmei Chen, Jianhao Pei and Huazhang Yang
    Citation: BMC Endocrine Disorders 2016 16:55
  2. We determined the proportion of the effects of body mass index (BMI) or its categories on cardiometabolic outcomes mediated through systolic blood pressure (SBP), total cholesterol and fasting glucose.

    Authors: Günay Can, Altan Onat, Eray Yurtseven, Yusuf Karadeniz, Tuğba Akbaş-Şimşek, Ayşem Kaya and Hüsniye Yüksel
    Citation: BMC Endocrine Disorders 2016 16:54
  3. Diabetes and hypertension increase arterial stiffness and cardiovascular events in all societies studied so far; sub-Saharan African studies are sparse. We investigated factors affecting arterial function in G...

    Authors: Kwame Yeboah, Daniel A. Antwi, Ben Gyan, Virginia Govoni, Charlotte E. Mills, J. Kennedy Cruickshank and Albert G. B. Amoah
    Citation: BMC Endocrine Disorders 2016 16:53
  4. To evaluate the neonatal and obstetric outcomes of pregnancies complicated by gestational diabetes mellitus (GDM). Screening and treatment – diet-only versus additional insulin therapy – were based on the 2010...

    Authors: Sarah H. Koning, Klaas Hoogenberg, Kirsten A. Scheuneman, Mick G. Baas, Fleurisca J. Korteweg, Krystyna M. Sollie, Bertine J. Schering, Aren J. van Loon, Bruce H.R. Wolffenbuttel, Paul P. van den Berg and Helen L. Lutgers
    Citation: BMC Endocrine Disorders 2016 16:52
  5. Current international guidelines advocate achieving at least a 30 % reduction in maximum plantar pressure to reduce the risk of foot ulcers in people with diabetes. However, whether plantar pressures differ in...

    Authors: Malindu E. Fernando, Robert G. Crowther, Peter A. Lazzarini, Kunwarjit S. Sangla, Scott Wearing, Petra Buttner and Jonathan Golledge
    Citation: BMC Endocrine Disorders 2016 16:51
  6. Early identification of children and adolescents with type 1 diabetes at high risk for development of complications is important, as early intervention may prevent further deterioration. Here we investigate th...

    Authors: Josine C. van der Heyden, Erwin Birnie, Dick Mul, Sarah Bovenberg, Henk J. Veeze and Henk-Jan Aanstoot
    Citation: BMC Endocrine Disorders 2016 16:49
  7. The term “adrenal fatigue” (“AF”) has been used by some doctors, healthcare providers, and the general media to describe an alleged condition caused by chronic exposure to stressful situations. Despite this, “...

    Authors: Flavio A. Cadegiani and Claudio E. Kater
    Citation: BMC Endocrine Disorders 2016 16:48

    The Erratum to this article has been published in BMC Endocrine Disorders 2016 16:63

  8. Twins may be at increased risk of dysglycaemic disorders due to adverse fetal conditions. Data from Africa regarding this association is limited. We studied impaired glucose tolerance (IGT) and other types of ...

    Authors: Ditte Egegaard Hennild, Morten Bjerregaard-Andersen, Luis Carlos Joaquím, Kaare Christensen, Morten Sodemann, Henning Beck-Nielsen and Dorte Møller Jensen
    Citation: BMC Endocrine Disorders 2016 16:46
  9. Fine needle aspiration biopsy (FNAB) is the tool of choice for evaluating thyroid nodules with the majority classified as benign following initial assessment. However, concern remains about false negative resu...

    Authors: Nigel Glynn, Mark J. Hannon, Sarah Lewis, Patrick Hillery, Mohammed Al-Mousa, Arnold D. K. Hill, Frank Keeling, Martina Morrin, Christopher J. Thompson, Diarmuid Smith, Derval Royston, Mary Leader and Amar Agha
    Citation: BMC Endocrine Disorders 2016 16:45
  10. Evidence on the role of irisin in insulin resistance is limited and controversial, and pathways between them remain unknown. We aimed to examine the independent effects of circulating irisin and different adip...

    Authors: Xiulin Shi, Mingzhu Lin, Changqin Liu, Fangsen Xiao, Yongwen Liu, Peiying Huang, Xin Zeng, Bing Yan, Suhuan Liu, Xiaoying Li, Shuyu Yang, Xuejun Li and Zhibin Li
    Citation: BMC Endocrine Disorders 2016 16:44
  11. As the field of Primary Aldosteronism (PA) becomes ever expanded, diagnosis of PA is increasingly diagnosed by endocrinologists. With increased PA screening, many of the cases are now found in patients with co...

    Authors: A. Tahir, K. McLaughlin and G. Kline
    Citation: BMC Endocrine Disorders 2016 16:43
  12. Screening for undiagnosed diabetes is not widely undertaken due to the high costs and invasiveness of blood sampling. Simple non-invasive tools to identify high risk individuals can facilitate screening. The m...

    Authors: P. Katulanda, N. R. Hill, I. Stratton, R. Sheriff, S. D. N. De Silva and D. R. Matthews
    Citation: BMC Endocrine Disorders 2016 16:42
  13. Patients with type 2 diabetes mellitus (T2DM) who participate in diabetes management programs have been shown to have better glycemic control and slower disease progression, although program participation rema...

    Authors: Janice M. S. Lopez, Bozena J. Katic, Marcy Fitz-Randolph, Richard A. Jackson, Wing Chow and C. Daniel Mullins
    Citation: BMC Endocrine Disorders 2016 16:41
  14. There is a scarcity of epidemiological researches examining the relationship between blood pressure (BP) and glucose level among older adults. The objective of the current study was to investigate the associat...

    Authors: Qun Yan, Dongmei Sun, Xu Li, Guoliang Chen, Qinghu Zheng, Lun Li, Chenhong Gu and Bo Feng
    Citation: BMC Endocrine Disorders 2016 16:40
  15. It is essential to anticipate and limit the social, economic and sanitary cost of type 2 diabetes (T2D), which is in constant progression worldwide.

    Authors: Sylvie Erpeldinger, Michaela B. Rehman, Christophe Berkhout, Christophe Pigache, Yves Zerbib, Francis Regnault, Emilie Guérin, Irène Supper, Catherine Cornu, Behrouz Kassaï, François Gueyffier and Rémy Boussageon
    Citation: BMC Endocrine Disorders 2016 16:39
  16. Diabetic foot ulceration is receiving more attention because of its high amputation and mortality rate. It is essential to establish the frequency of amputations in people with diabetes after any change to the...

    Authors: Chuan Wang, Lifang Mai, Chuan Yang, Dan Liu, Kan Sun, Weidong Song, Baoming Luo, Yan Li, Mingtong Xu, Shaoling Zhang, Fangping Li, Meng Ren and Li Yan
    Citation: BMC Endocrine Disorders 2016 16:38
  17. Congenital adrenal hyperplasia (CAH) due to steroid 11β-hydroxylase deficiency (11β-OHD) is a rare form of CAH associated with low renin hypertension, hypokalemia, hyperandrogenemia and ambiguous genitalia in ...

    Authors: Pattaranatcha Charnwichai, Patra Yeetong, Kanya Suphapeetiporn, Vichit Supornsilchai, Taninee Sahakitrungruang and Vorasuk Shotelersuk
    Citation: BMC Endocrine Disorders 2016 16:37
  18. The aim of this study was to compare the efficacy, safety, costs, and cost-effectiveness of biphasic insulin aspart 30 (BIAsp 30) with NPH plus regular human insulin (NPH/Reg) in patients with type 2 diabetes ...

    Authors: Amir Farshchi, Rokhsareh Aghili, Maryam Oskuee, Marjan Rashed, Sina Noshad, Abbas Kebriaeezadeh, Maryam Kia and Alireza Esteghamati
    Citation: BMC Endocrine Disorders 2016 16:35
  19. Oxytocin (OT) emerges as a drug for the treatment of diabetes and obesity. The entire OT system is synthesized in the rat and human heart. The direct myocardial infusion with OT into an ischemic or failing hea...

    Authors: Marek Jankowski, Tom L. Broderick and Jolanta Gutkowska
    Citation: BMC Endocrine Disorders 2016 16:34
  20. Pancreatic β-cell dysfunction resulting from inflammation has been recognized to contribute to type 2 diabetes mellitus (T2DM). Netrin-1 is a new indicator of subclinical inflammation and it has a role in β-ce...

    Authors: Chenxiao Liu, Xianjin Ke, Ying Wang, Xiu Feng, Qi Li, Ying Zhang, Jian Zhu and Qian Li
    Citation: BMC Endocrine Disorders 2016 16:33
  21. To describe common type 2 diabetes treatment intensification regimens, patients’ characteristics and changes in glycated hemoglobin (HbA1c) and body mass index (BMI).

    Authors: Christianne L. Roumie, Robert A. Greevy, Carlos G. Grijalva, Adriana M. Hung, Xulei Liu and Marie R. Griffin
    Citation: BMC Endocrine Disorders 2016 16:32
  22. Patients with myocardial infarction (MI) have a high mortality. Therefore, new risk markers and predictors of an adverse outcome for MI are required. The role of hyperglycemia in the development of cardiovascu...

    Authors: Victoria Karetnikova, Olga Gruzdeva, Evgenya Uchasova, Anastasia Osokina and Olga Barbarash
    Citation: BMC Endocrine Disorders 2016 16:31
  23. Advance in medicine has led to an increase in life expectancy of elderly diabetic patients especially on the growing population called the “oldest old”, those in their mid-80s upwards. The aim of this study is...

    Authors: Thewjitcharoen Yotsapon, Krittiyawong Sirinate, Wanothayaroj Ekgaluck, Vongterapak Somboon, Anuntakulnatee Tawee, Kittipoom Worawit, Nakasatien Soontaree and Himathongkam Thep
    Citation: BMC Endocrine Disorders 2016 16:30
  24. Type 1 Diabetes Mellitus is a rapidly growing problem in Tanzania. Children and adolescents with type 1 diabetes have previously been found to have poor glycaemic control and high prevalence of complications. ...

    Authors: Mariam Noorani, Kaushik Ramaiya and Karim Manji
    Citation: BMC Endocrine Disorders 2016 16:29
  25. The provision of health education involving self-care and good adherence to medications has been acknowledged to be a cost effective strategy for improving quality of life of diabetes patients. We assessed lev...

    Authors: Tefera Kassahun, Hailay Gesesew, Lillian Mwanri and Tesfahun Eshetie
    Citation: BMC Endocrine Disorders 2016 16:28
  26. Associations between metabolic syndrome (MetS) and osteoporotic fracture have been reported. However, the epidemiological studies are not conclusive. The objective of the study was to determine whether metabol...

    Authors: Li Qin, Zhen Yang, Weiwei Zhang, Hongxia Gu, Xiaoyong Li, Lingfei Zhu, Shuai Lu, Yin Xing, Hongmei Zhang, Yixin Niu, Guang Ning and Qing Su
    Citation: BMC Endocrine Disorders 2016 16:27
  27. Effective prevention of type 2 diabetes (T2D) requires early identification of high-risk individuals who might benefit from intervention. We sought to determine whether low serum testosterone, a novel risk fac...

    Authors: Evan Atlantis, Paul Fahey, Sean Martin, Peter O’Loughlin, Anne W. Taylor, Robert J. Adams, Zumin Shi and Gary Wittert
    Citation: BMC Endocrine Disorders 2016 16:26
  28. Diabetic retinopathy (DRP) is a common microvascular complication seen in patients with type 1 diabetes mellitus (T1DM). The effects of T1DM and concomitant (proliferative) DRP on retinal blood flow are curren...

    Authors: Hoang-Ton Nguyen, Eelco van Duinkerken, Frank D. Verbraak, Bettine C. P. Polak, Peter J. Ringens, Michaela Diamant and Annette C. Moll
    Citation: BMC Endocrine Disorders 2016 16:25
  29. Prevalence of diabetes and cardiovascular (CVD) disease amongst UK South Asians is higher than in the general population. Non-adherence to medicines may lead to poor clinical outcomes for South Asian patients ...

    Authors: Kanta Kumar, Sheila Greenfield, Karim Raza, Paramjit Gill and Rebecca Stack
    Citation: BMC Endocrine Disorders 2016 16:24
  30. In order to accurately interpret neonatal thyroid function tests (TFTs), it is necessary to have population specific reference intervals (RIs) as there is significant variation across different populations pos...

    Authors: Geoffrey Omuse, Ali Kassim, Francis Kiigu, Syeda Ra’ana Hussain and Mary Limbe
    Citation: BMC Endocrine Disorders 2016 16:23

    The Erratum to this article has been published in BMC Endocrine Disorders 2017 17:21

  31. Tolvaptan is the only vasopressin V2 receptor antagonist licensed by the European Medicines Agency for the treatment of hyponatraemia (HN) secondary to the syndrome of inappropriate antidiuretic hormone secretion...

    Authors: Clare Jamookeeah, Paul Robinson, Karl O’Reilly, Johan Lundberg, Martin Gisby, Michael Ländin, Jakob Skov and David Trueman
    Citation: BMC Endocrine Disorders 2016 16:22
  32. Safe and effective insulin therapy for diabetes mellitus requires initial dose titration and regular adjustments based on blood glucose (BG) monitoring. Our objective was to explore the use of BG measurement i...

    Authors: Kaisa Miikkulainen, Antonio Caruso, Oliver Mast, Rongrong Zhang and Oleg Borisenko
    Citation: BMC Endocrine Disorders 2016 16:21
  33. Type B insulin resistance is a rare autoimmune disease characterized by the presence of autoantibodies against the insulin receptor. Helicobacter pylori (H pylori) infection may play a causative role in the au...

    Authors: Guo-Qing Yang, Yi-Jun Li, Jing-Tao Dou, Bao-An Wang, Ju-Ming Lu and Yi-Ming Mu
    Citation: BMC Endocrine Disorders 2016 16:20
  34. Small intestinal neuroendocrine tumors (SI-NETs) originate from the enterochromaffin cells in the ileum and jejunum. The knowledge about genetic and epigenetic abnormalities is limited. Low mRNA expression lev...

    Authors: Katarina Edfeldt, Per Hellman, Gunnar Westin and Peter Stalberg
    Citation: BMC Endocrine Disorders 2016 16:19
  35. The ubiquitin conjugating enzyme E2L3 (UBE2L3) gene is associated with susceptibility to many autoimmune diseases. The aim of this study was to investigate the association between UBE2L3 gene and autoimmune th...

    Authors: Yu Wang, Yuan-feng Zhu, Qiong Wang, Jing Xu, Ni Yan, Jian Xu, Liang-feng Shi, Shuang-tao He and Jin-an Zhang
    Citation: BMC Endocrine Disorders 2016 16:18
  36. Islet cell transplantation is a method to stabilize type 1 diabetes patients with hypoglycemia unawareness and unstable blood glucose levels by reducing insulin dependency and protecting against severe hypogly...

    Authors: Klemens Wallner, A. M. James Shapiro, Peter A. Senior and Christopher McCabe
    Citation: BMC Endocrine Disorders 2016 16:17
  37. Many patients with acromegaly do not achieve biochemical control with first-generation somatostatin analogues. A large, multicenter, randomized, Phase III core study demonstrated that pasireotide LAR had signi...

    Authors: Marcello D. Bronstein, Maria Fleseriu, Sebastian Neggers, Annamaria Colao, Michael Sheppard, Feng Gu, Chiung-Chyi Shen, Mônica Gadelha, Andrew J. Farrall, Karina Hermosillo Reséndiz, Matthieu Ruffin, YinMiao Chen and Pamela Freda
    Citation: BMC Endocrine Disorders 2016 16:16
  38. Women with type 2 diabetes mellitus (T2DM) have a higher risk of fractures despite increased bone mineral density (BMD). In experimental studies a potential role of plasminogen activator inhibitor-1 (PAI-1) in...

    Authors: Silvija Canecki-Varžić, Ivana Prpić-Križevac and Ines Bilić-Ćurčić
    Citation: BMC Endocrine Disorders 2016 16:14
  39. The number and activity of circulating endothelial progenitor cells (EPCs) in prehypertension is preserved in premenopausal women. However, whether this favorable effect still exists in prehypertensive premeno...

    Authors: Haitao Zeng, Yanping Jiang, Hailin Tang, Zi Ren, Gaofeng Zeng and Zhen Yang
    Citation: BMC Endocrine Disorders 2016 16:13
  40. There is rising incidence of gastroenteropancreatic neuroendocrine tumours (GEP- NETs) in many parts of the world, but epidemiological data from Asian populations is rare.

    Authors: Doris T. Chan, Andrea O. Y. Luk, W. Y. So, Alice P. S. Kong, Francis C. C. Chow, Ronald C. W. Ma and Anthony W. I. Lo
    Citation: BMC Endocrine Disorders 2016 16:12
  41. The relationship between alterations in thyroid function and cognitive deficits has been investigated in several previous studies. Hypo-or hyperthyroidism and, to a lesser extent, subclinical thyroid dysfuncti...

    Authors: Yao Hu, Zhi-cheng Wang, Qi-hao Guo, Wei Cheng and Yan-wen Chen
    Citation: BMC Endocrine Disorders 2016 16:11
  42. Information about the achievement of glycemic targets in patients with type 2 diabetes according to different individualization strategies is scarce. Our aim was to analyze the allocation of type 2 diabetic pa...

    Authors: I. Miñambres, J. J. Mediavilla, J. Sarroca and A. Pérez
    Citation: BMC Endocrine Disorders 2016 16:10
  43. The rare incidence of neuroendocrine neoplasms (NENs) has contributed to a paucity of large epidemiologic studies of patients with this condition. We investigated the occurrence and clinicopathologic features ...

    Authors: George C. Nikou, Kalliopi Pazaitou-Panayiotou, Dimitrios Dimitroulopoulos, Georgios Alexandrakis, Pavlos Papakostas, Michalis Vaslamatzis, Philippos Kaldrymidis, Vyron Markussis and Anna Koumarianou
    Citation: BMC Endocrine Disorders 2016 16:8
  44. Experiments in mice initially suggested a role for the protein angiopoietin-like 8 (ANGPTL8) in glucose homeostasis. However, subsequent experiments in model systems have challenged this proposed role. We soug...

    Authors: Katharine R. Clapham, Audrey Y. Chu, Jennifer Wessel, Pradeep Natarajan, Jason Flannick, Manuel A. Rivas, Samantha Sartori, Roxana Mehran, Usman Baber, Valentin Fuster, Robert A. Scott, Daniel J. Rader, Michael Boehnke, Mark I. McCarthy, David M. Altshuler, Sekar Kathiresan…
    Citation: BMC Endocrine Disorders 2016 16:7

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