Table 1 Characteristic of women who responded to 2.5 mg letrozole and who did not respond to 2.5 mg letrozole
Variables | Response to 2.5 mg letrozole (n = 131) | No response to 2.5 mg letrozole (n = 83) | P-value |
|---|---|---|---|
Age, y (mean ± SD) | 29.14 ± 3.18 | 28.61 ± 3.46 | 0.258 |
BMI, kg/m2 (mean ± SD) | 23.09 ± 2.86 | 23.63 ± 3.10 | 0.197 |
Waist-hip ratio (mean ± SD) | 0.84 ± 0.09 | 0.84 ± 0.06 | 0.557 |
Prior Gravidity, n (%) | 37 (29.1) | 21 (26.2) | 0.771 |
Prior parity, n (%) | 13 (10.2) | 8 (10.0) | 1.0 |
Menarche, y (mean ± SD) | 13.28 ± 1.29 | 13.69 ± 1.45 | 0.042 |
mF-G score (mean ± SD) | 3.82 ± 3.94 | 3.90 ± 3.59 | 0.886 |
AMH, ng/ml (mean ± SD) | 8.99 ± 4.94 | 10.52 ± 5.18 | 0.042 |
Baseline FSH, IU/L (mean ± SD) | 6.65 ± 1.84 | 6.89 ± 1.87 | 0.379 |
Baseline LH, IU/L (mean ± SD) | 11.06 ± 6.03 | 13.88 ± 7.34 | 0.004 |
Baseline LH/FSH (mean ± SD) | 1.69 ± 0.87 | 2.09 ± 1.10 | 0.005 |
Baseline E2, ng/mL (mean ± SD) | 55.34 ± 35.10 | 54.16 ± 35.56 | 0.818 |
Baseline PRL, ng/mL (mean ± SD) | 13.00 ± 6.91 | 11.35 ± 5.70 | 0.078 |
Total testosterone, ng/mL (mean ± SD) | 0.69 ± 0.33 | 0.72 ± 0.28 | 0.521 |
SHGB, nmol/L (mean ± SD) | 43.73 ± 32.79 | 41.71 ± 39.02 | 0.703 |
FAI (mean ± SD) | 8.40 ± 8.20 | 10.34 ± 10.62 | 0.174 |
DHEA-S, ug/dL (mean ± SD) | 270.88 ± 121.02 | 286.75 ± 135.42 | 0.412 |
HOMA-IR (mean ± SD) | 2.64 ± 2.32 | 3.42 ± 3.80 | 0.075 |