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Table 2 Genotype frequencies for UCP1 and UCP2 SNPs in populations from the IRAS Family Study

From: The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS Family Study

   

African American

Hispanic

   

Los Angeles

San Luis Valley

San Antonio

UCP1

A-3826G

A/A, % (n)*

17.4 (50)

34.0 (108)

35.2 (174)

  

A/G, % (n)

40.4 (116)

51.9 (165)

50.4 (249)

  

G/G, % (n)

42.2 (121)

14.2 (45)

14.4 (71)

  

Total (n)

(287)

(318)

(494)

 

A64T

G/G, % (n)

83.1 (236)

83.8 (263)

83.1 (409)

  

G/A, % (n)

16.2 (46)

15.6 (49)

15.9 (78)

  

A/A, % (n)

0.7 (2)

0.6 (2)

1.0 (5)

  

Total (n)

(284)

(314)

(492)

 

M229L

A/A, % (n)

93.0 (264)

84.4 (265)

82.9 (402)

  

A/T, % (n)

7.0 (20)

14.7 (46)

16.1 (78)

  

T/T, % (n)

0 (0)

1.0 (3)

1.0 (5)

  

Total (n)

(284)

(314)

(485)

UCP2

G-866A

G/G, % (n)

32.8 (89)

31.1 (94)

27.2 (132)

  

G/A, % (n)

48.0 (130)

48.7 (147)

46.7 (227)

  

A/A, % (n)

19.2 (52)

20.2 (61)

26.1 (127)

  

Total (n)

(271)

(302)

(486)

 

A55V

C/C, % (n)

28.8 (82)

28.3 (89)

26.3 (129)

  

C/T, % (n)

51.2 (146)

53.3 (168)

47.4 (232)

  

T/T, % (n)

20.0 (57)

18.4 (58)

26.3 (129)

  

Total (n)

(285)

(315)

(490)

  1. *n = the number of individuals successfully genotyped.