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Table 2 Insulin sensitivity and NEFA suppression

From: Differences in insulin sensitivity, lipid metabolism and inflammation between young adult Pakistani and Norwegian patients with type 2 diabetes: a cross sectional study

 

Norwegians

Pakistanis

p

GIR40

468.4 (587.3)

339.8 (468.0)

0.456

ISI40

79.7 (137.9)

57.1 (74.1)

0.289

S-insulin end low step(pmol/l)

546 (336)

715 (243)

0.041

GIR400

2055.6 (907.0)

1661.1 (672.3)

0.080

ISI400

20.7 (17.2)

14.2 (7.3)

0.016

S-insulin end high step (pmol/l)

9505 (2738)

11082 (2922)

0.069

Fasting p-NEFA (mmol/l)

0.59 (0.43)

0.50 (0.29)

0.394

NEFA suppression 0–30 minutes (%)

71.2 (42.1)

41.9 (90.6)

0.042

  1. Table 2: Data are presented as median (interquartile range), and comparisons are made using the Mann–Whitney U test. In bold: p < 0.05. GIR40 = glucose infusion ratelow step, ISI40 = glucose infusion rate/s-insulinlow step, GIR400 = glucose infusion ratehigh step, ISI400 = glucose infusion rate/s-insulinhigh step. GIR is expressed as μmol/m2/min, and ISI as 100 × μmol/m2/min/s-Ins. NEFA = non-esterified fatty acids. Number of Norwegians and Pakistanis were: during the low step, n = 19 and 16, respectively. During the high step, n = 19 and 14, respectively, and for NEFA measurements, n = 13 and 15, respectively.