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Table 6 Comparison of clinical parameters, biochemistry and cure rate between 2009 (n:28) and current (n:110) study

From: Characteristics, management and outcomes of primary hyperparathyroidism from 2009 to 2021: a single centre report from South Africa

 

2009

2021

P

 

n:28

n:110

 

Symptomatic (%)

92.9

62.7

0.002

BMI (kg/m2)

28.1 (26.1; 31.1)

27.3 (23.4; 32.9)

0.462

Pre-operative

   

 Serum Calcium (mmol/l)

3.00 (2.9; 3.2)

2.83 (2.6; 3.1)

0.010

 Serum PTH (pmol/l)

16.85 (9.9; 40.7)

23.3 (16.0; 45.4)

0.824

 25-OH Vit D (nmol/l)

39 (26; 47.9)

42.9 (33.3; 62.9)

0.488

 Serum ALP (U/l)

98 (79; 125)

117.5 (89; 145.5)

0.133

 24-hour urine calcium (mmol/day)

5.1 (2.5; 6.1)

3.34 (1.59; 5.4)

0.654

Post-operative

   

 Serum PTH (pmol/l)

2.3 (1.1; 4.5)

4.4 (2.1; 8.8)

0.044

 Serum Calcium (mmol/l)

2.31 (2.2; 2.4)

2.25 (2.15; 2.4)

0.233

Cure (%)

94.7

95.2

0.819

  1. Data are presented as Median (IQR) or %
  2. BMI: body mass index; PTH: Parathyroid Hormone, 25-OH Vit D: 25-hydroxyvitamin D; ALP: Alkaline phosphatase