Table 1 Clinical and biochemical characteristics of the total study group at presentation (n: 110)

Sex (M : F)

14 : 96

12.7 : 87.3

Ethnicity

Indian

48

43.6

African

45

40.9

White

16

14.5

Mixed Race (Coloured)

1

1

Range

Age (years)

57 (44; 66.8)

13–84

BMI (kg/m²)

27.4 (23.4; 32.9)

14.55–49.98

Systolic Blood Pressure (mmHg)

130 (116; 146)

92–186

Diastolic Blood Pressure (mmHg)

75 (66; 82)

46–104

 N

%

Past History Attributable To PHPT

43

39.1

 Nephrolithiasis

23

20.9

 Non-trauma fracture

8

7.3

 Osteoporosis

7

6.4

 Peptic Ulcer Disease

6

5.5

 Depression

3

2.7

 Pancreatitis

2

2

 Psychosis

1

1

Other Medical History

N

%

Hypertension

66

60.5

Diabetes Mellitus

29

26.4

Dyslipidaemia

31

28.2

Malignancy

10

9.1

Baseline Biochemistry

Normal Reference Range

Serum Calcium (mmol/l)

2.87 ± 0.34

2.15–2.50

Serum Magnesium (mmol/l)

0.82 ± 0.12

0.63–1.05

Serum Phosphate (mmol/l)

0.87 ± 0.20

0.78–1.42

Serum Creatinine (µmol/l)

71 (58; 95)

49–90

eGFR (CKD-EPI) (ml/min/1.73m²)

85.9 ± 33.4

> 60

Serum ALP (U/L)

117.5 (89; 145.5)

42–98

Serum PTH (pmol/l)

23.3 (16.0; 45.4)

2.0-8.5

*Serum 25-OH Vitamin D (nmol/l) (n:95)

42.9 (33.3; 62.9)

> 50

Vitamin D deficiency (n;%)

16; 16.8

24-hour urine calcium (mmol/day)

3.3 (1.6; 5.4)

2.5–7.5