Variable | Unadjusted | Model 1 | Model 2 | Model 3 | ||||
---|---|---|---|---|---|---|---|---|
HR(95%CI) | p value | HR(95%CI) | p value | HR(95%CI) | p value | HR(95%CI) | p value | |
Men | ||||||||
 FM | 1. 1 ( 1.08 ~ 1. 11) | < 0.001 | 1. 11 ( 1.09 ~ 1. 13) | < 0.001 | 1. 11 ( 1.09 ~ 1. 12) | < 0.001 | 1.05 ( 1.03 ~ 1.07) | < 0.001 |
  1st tertile(< 21.783) | 1(Ref) |  | 1(Ref) |  | 1(Ref) |  | 1(Ref) |  |
  2st tertile(21.783 ~ 26.335) | 1.28 (0.89 ~ 1.85) | 0. 183 | 1.23 (0.85 ~ 1.77) | 0.271 | 1.28 (0.88 ~ 1.84) | 0. 192 | 0.82 (0.56 ~ 1. 19) | 0.29 |
  3st tertile(> 26.335) | 3.43 (2.51 ~ 4.7) | < 0.001 | 3.47 (2.53 ~ 4.74) | < 0.001 | 3.57 (2.61 ~ 4.89) | < 0.001 | 1.25 (0.88 ~ 1.79) | 0.211 |
  p for trend |  | < 0.001 |  | < 0.001 |  | < 0.001 |  | 0.077 |
 LM | 1. 1 ( 1.07 ~ 1. 12) | < 0.001 | 1. 13 ( 1. 11 ~ 1. 16) | < 0.001 | 1. 13 ( 1. 1 ~ 1. 16) | < 0.001 | 1.04 ( 1.01 ~ 1.07) | 0.006 |
  1st tertile(< 39.37) | 1(Ref) |  | 1(Ref) |  | 1(Ref) |  | 1(Ref) |  |
  2st tertile(39.37 ~ 42.81) | 0.84 (0.61 ~ 1. 16) | 0.296 | 1.02 (0.73 ~ 1.42) | 0.909 | 1.05 (0.75 ~ 1.47) | 0.766 | 0.76 (0.54 ~ 1.07) | 0. 112 |
  3st tertile(> 42.81) | 1.87 ( 1.42 ~ 2.46) | < 0.001 | 2.59 ( 1.93 ~ 3.47) | < 0.001 | 2.6 ( 1.95 ~ 3.49) | < 0.001 | 1. 13 (0.83 ~ 1.56) | 0.434 |
  p for trend |  | < 0.001 |  | < 0.001 |  | < 0.001 |  | 0.287 |
 PF | 1.23 ( 1.2 ~ 1.26) | < 0.001 | 1.24 ( 1.2 ~ 1.27) | < 0.001 | 1.23 ( 1.2 ~ 1.27) | < 0.001 | 1. 11 ( 1.07 ~ 1. 16) | < 0.001 |
  1st tertile(< 34.343) | 1(Ref) |  | 1(Ref) |  | 1(Ref) |  | 1(Ref) |  |
  2st tertile(34.343 ~ 36.976) | 2.24 ( 1.49 ~ 3.37) | < 0.001 | 2.04 ( 1.35 ~ 3.08) | 0.001 | 2.08 ( 1.38 ~ 3. 13) | < 0.001 | 1.03 (0.67 ~ 1.58) | 0.895 |
  3st tertile(> 36.976) | 5.63 (3.88 ~ 8. 17) | < 0.001 | 4.88 (3.34 ~ 7. 12) | < 0.001 | 5.01 (3.43 ~ 7.3) | < 0.001 | 1.52 (0.99 ~ 2.33) | 0.055 |
  p for trend |  | < 0.001 |  | < 0.001 |  | < 0.001 |  | 0.01 |
Women | ||||||||
 FM | 1.2 ( 1. 16 ~ 1.23) | < 0.001 | 1.2 ( 1. 16 ~ 1.23) | < 0.001 | 1. 19 ( 1. 16 ~ 1.23) | < 0.001 | 1. 11 ( 1.07 ~ 1. 16) | < 0.001 |
  1st tertile(< 6.717) | 1(Ref) |  | 1(Ref) |  | 1(Ref) |  | 1(Ref) |  |
  2st tertile (6.717 ~ 10.356) | 2.52 ( 1. 13 ~ 5.63) | 0.024 | 2.39 ( 1.07 ~ 5.34) | 0.033 | 2.37 ( 1.06 ~ 5.28) | 0.036 | 1.76 (0.78 ~ 3.98) | 0. 175 |
  3st tertile (> 10.356) | 8.72 (4.32 ~ 17.61) | < 0.001 | 7.45 (3.68 ~ 15. 1) | < 0.001 | 7.53 (3.71 ~ 15.28) | < 0.001 | 2.52 ( 1. 15 ~ 5.55) | 0.022 |
  p for trend |  | < 0.001 |  | < 0.001 |  | < 0.001 |  | 0.018 |
 LM | 1.08 ( 1.03 ~ 1. 13) | 0.001 | 1. 11 ( 1.06 ~ 1. 16) | < 0.001 | 1. 1 ( 1.05 ~ 1. 16) | < 0.001 | 1.03 (0.98 ~ 1.07) | 0.274 |
  1st tertile(< 40.075) | 1(Ref) |  | 1(Ref) |  | 1(Ref) |  | 1(Ref) |  |
  2st tertile(40.075 ~ 43.432) | 0.94 (0.52 ~ 1.69) | 0.83 | 1.06 (0.58 ~ 1.92) | 0.853 | 1.01 (0.56 ~ 1.84) | 0.965 | 1. 1 (0.6 ~ 2.02) | 0.77 |
  3st tertile(> 43.432) | 1.64 (0.97 ~ 2.78) | 0.062 | 2.02 ( 1. 19 ~ 3.44) | 0.01 | 2.01 ( 1. 18 ~ 3.42) | 0.011 | 1.4 (0.79 ~ 2.49) | 0.254 |
  p for trend |  | 0.038 |  | 0.006 |  | 0.006 |  | 0.236 |
 PF | 1.31 ( 1.26 ~ 1.37) | < 0.001 | 1.3 ( 1.24 ~ 1.36) | < 0.001 | 1.3 ( 1.24 ~ 1.36) | < 0.001 | 1. 18 ( 1. 11 ~ 1.26) | < 0.001 |
  1st tertile(< 18.47) | 1(Ref) |  | 1(Ref) |  | 1(Ref) |  | 1(Ref) |  |
  2st tertile(18.47 ~ 21.412) | 2.52 ( 1. 17 ~ 5.44) | 0.019 | 2.39 ( 1. 11 ~ 5. 16) | 0.026 | 2.4 ( 1. 11 ~ 5. 18) | 0.026 | 1.58 (0.72 ~ 3.48) | 0.255 |
  3st tertile(> 21.412) | 9 (4.57 ~ 17.72) | < 0.001 | 7.34 (3.7 ~ 14.56) | < 0.001 | 7.4 (3.72 ~ 14.7) | < 0.001 | 2.21 ( 1.03 ~ 4.73) | 0.041 |
  p for trend |  | < 0.001 |  | < 0.001 |  | < 0.001 |  | 0.033 |