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Table 3 The clinical characteristics and CA 19 − 9 level of the HbA1c ≥ 9% group and control group

From: Effect of glycotoxicity and lipotoxicity on carbohydrate antigen 19 − 9 in the patients with diabetes

Variables

The HbA1c ≥ 9% group

(n = 186)

Non-diabetes controls

(n = 200)

p value

CA 19−9 levels (U/ml)

22.0 ± 17.4

13.6 ± 8.9

< 0.001*

Proportion of objects with abnormal CA 19−9

26/186 (14.0%)

5/200 (2.5%)

< 0.001*

Age (years)

55.4 ± 13.3

57.5 ± 14.2

0.153

Female sex

49 (26.3%)

64 (32.0%)

0.222

BMI (kg/m2)

24.8 ± 3.7

25.4 ± 3.8

0.587

HbA1c (%)

11.37 ± 1.91

4.8 ± 1.02

< 0.001*

Systolic blood pressure (mmHg)

128.9 ± 20.2

130.1 ± 15.6

0.438

Diastolic blood pressure (mmHg)

81.5 ± 12.1

76.8 ± 11.9

0.267

Uric acid (µmol/l)

305.7 ± 94.2

326.5 ± 91.2

0.122

Total cholesterol (mmol/l)

4.77 ± 1.27

4.68 ± 1.39

0.382

Triglycerides (mmol/l)

2.02 ± 1.82

1.93 ± 1.74

0.424

Creatinine (µmol/l)

64.6 ± 23.2

67.6 ± 15.3

0.125

ALT (U/L)

26.6 ± 17.6

26.9 ± 18.2

0.691

  1. CA 19 − 9, carbohydrate antigen 19 − 9; BMI, body mass index; HbA1c, glycosylated hemoglobin; ALT, alanine aminotransferase; * p value was less than 0.01