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Table 1 Patient characteristics

From: Association of serum asprosin with metabolic dysfunction-associated fatty liver disease in older adult type 2 diabetic patients: a cross-sectional study

Clinical data

Non-MAFLD group (n = 105)

MAFLD group (n = 114)

P

Age, years

72.0 (69.0, 75.0)

71.0 (68.0, 74.0)

0.045

Sex

  

0.699

Male

46 (43.8%)

47 (41.23%)

 

Female

59 (56.2%)

67 (58.77%)

 

BMI, kg/cm2

23.8 (21.5, 26.0)

26.1 (24.2, 27.8)

< 0.001

Time from T2DM diagnosis, years

14.0 (9.5, 20.0)

10.0 (5.0, 15.0)

< 0.001

WHR

0.90 (0.89, 0.96)

0.92 (0.90, 1.00)

0.018

Drinking history

31 (29.5%)

32 (28.1%)

0.812

Diabetes history

15 (14.3%)

16 (14.0%)

0.958

SBP (mmHg)

130 (120, 142.5)

130 (120, 140)

0.615

DBP (mmHg)

80 (70, 80)

80 (70, 80)

0.252

TC (mM)

4.72 ± 1.01

4.60 ± 1.04

0.412

TG (mM)

1.26 (0.92, 1.64)

1.57 (1.21, 2.22)

< 0.001

HDL-C (mM)

1.04 (0.89, 1.35)

0.97 (0.82, 1.09)

0.002

LDL-C (mM)

2.85 ± 0.86

2.81 ± 0.95

0.733

ALT (IU/L)

14.00 (10.00, 19.50)

17.00 (13.00, 27.25)

0.001

AST (IU/L)

17.00 (13.50, 21.00)

18.00 (14.00, 24.00)

0.223

GGT (IU/L)

18.00 (14.00, 25.50)

24.00 (18.00, 34.25)

< 0.001

Scr (µmol/L)

61.00 (53.50, 73.50)

60.00 (51.75, 71.00)

0.406

Asprosin (pg/ml)

255.24 ± 82.52

291.71 ± 73.69

0.001

eGFR (mL/min/1.73 m2)

128.78 (106.66, 154.52)

131.28 (114.72, 158.91)

0.612

HbA1C (%)

8.50 (7.15, 10.55)

8.95 (7.78, 10.4)

0.233

FPG (mM)

7.65 (5.98, 9.77)

7.41 (6.50, 9.86)

0.903

2hPG (mM)

12.78 ± 4.59

13.20 ± 3.79

0.463

FINS (mIU/L)

2.84 (2.00, 4.83)

4.96 (3.43, 7.24)

< 0.001

HOMA-IR

1.07 (0.6, 1.69)

1.71 (1.29, 2.45)

< 0.001

FC-P (nM)

1.81 (1.17, 2.43)

1.94 (1.12, 2.48)

0.614

  1. All data are median (25th, 75th), mean ± standard deviation, or n (%)
  2. MAFLD, metabolic dysfunction-associated fatty liver disease; BMI, body mass index; WHR, waist-hip ratio; SBP, systolic blood pressure; DBP, diastolic blood pressure; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LCL-D, low-density lipoprotein cholesterol; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, γ-glutaryl transferase; Scr, serum creatinine; eGFR, estimated glomerular filtration rate; HbA1c, glycated hemoglobin; FPG, fasting plasma glucose; 2hPG, 2-hour postprandial glucose; FINS, fasting insulin; HOMA-IR, homeostasis model assessment of insulin resistance; FC-P, fasting C-peptide