Experimental Groups Histopathological Variables | Control | DM | DM + hWJ-MSCs-CM |
---|---|---|---|
Pancreas tissue | |||
Number of pancreatic islets | 15.51 ± 1.82 | 5.23 ± 0.51*** | 9.93 ± 1.23** # |
Mean diameter of islets (µm) | 642.32 ± 74.50 | 258.62 ± 52.60**** | 566.23 ± 50.35## |
Kidney tissue | |||
Dilatation of the urinary space | 0.00 ± 0.00 | 3.2 ± 0.03**** | 1.2 ± 0.04**** ## |
Interstitial hemorrhage | 0.00 ± 0.00 | 2.8 ± 0.07**** | 1.3 ± 0.01**** ## |
Mononuclear infiltration | 0.00 ± 0.00 | 3.1 ± 0.03**** | 1.8 ± 0.02**** ## |
Liver tissue | |||
Hepatic necrosis | 0.00 ± 0.00 | 1.62 ± 0.04**** | 0.48 ± 0.03**** #### |
Hepatic degeneration | 0.00 ± 0.00 | 2.55 ± 0.05**** | 0.66 ± 0.02**** #### |
Mononuclear cell inflammation | 0.00 ± 0.00 | 1.51 ± 0.04**** | 0.55 ± 0.02**** #### |