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Fig. 8 | BMC Endocrine Disorders

Fig. 8

From: Effects of conditioned media derived from human Wharton’s jelly mesenchymal stem cells on diabetic nephropathy and hepatopathy via modulating TGF-β and apelin signaling pathways in male rats

Fig. 8

Hematoxylin and Eosin (H&E) staining of liver tissue; photomicrographs of the control, diabetic (without treatment), and diabetic rats treated with condition media (CM) of human umbilical cord Wharton’s jelly mesenchymal stem cells (hWJ-MSCs), [×200 and ×400 magnifications; Scale bar: 50 μm]. Microscopic views of the liver of control rats (A and B); section from the liver of the diabetic group with degenerated hepatocytes, karyolysed nuclei, extensive necrosis (C), mild fibrosis, bile duct proliferation (C, arrow), and lymphatic cell infiltration in parenchymal areas (D, two head-arrows); diabetic rats treated with condition media without any specific pathological changes except a mild degeneration and locally inflammatory cell infiltration (E and F)

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