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Fig. 3 | BMC Endocrine Disorders

Fig. 3

From: Lipid variability and risk of microvascular complications in patients with diabetes: a systematic review and meta-analysis

Fig. 3

This diagram illustrates the impact of lipid alterations and heightened lipid concentrations, ultimately precipitating the development of diabetic microvascular complications. VEGF: Vascular endothelial growth factor, eNOS: Endothelial nitric oxide synthase, NO: Nitric oxide, PDGF: Platelet-derived growth factor, Ang-Tie: angiopoietin-Tie, TNF-α: Tumor Necrosis Factor-alpha, NF-kB: Nuclear factor kappa B, TGF-β: Transforming growth factor-β, mTORC1: mammalian target of rapamycin complex 1, MCP-1: Monocyte chemoattractant protein-1, AMPK: Adenosine monophosphate-activated protein kinase, PGC-1α: Peroxisome proliferator-activated receptor-gamma coactivator(PGC)-1alpha, SC-axon: Schwann cells axon, MCT: Monocarboxylate Transporter 1

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BMC Endocrine Disorders

ISSN: 1472-6823

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