Table 1 Characteristics of studies that provided genotype frequencies evaluating the effects of MCP-1 rs1024611 polymorphism on DN and T2DM risk
No | First author, year | Country | Ethnicity | Sample sizea | T2DMb | DNc | Controld | HWE(T2DM/ Control) | NOS score |
|---|---|---|---|---|---|---|---|---|---|
1 | Simeoni, 2004 [25] | Germany | Caucasians | 632/-/2568 | 363/222/47 | - | 1335/1043/190 | -/0.482 | 8 |
2 | Joo, 2007 [19] | Korea | Asians | 169/164/- | 23/78/68 | 26/73/65 | - | 0.933/- | 7 |
3 | Moon, 2007 [23] | Korea | Asians | 112/112/230 | 11/50/51 | 16/61/35 | 41/102/87 | 0.804/0.249 | 8 |
4 | Chen, 2007 [15] | China (Hunan) | Asians | 86/94/102 | 24/40/22 | 24/44/26 | 31/47/24 | 0.521/0.454 | 6 |
5 | Karadeniz, 2010 [20] | Turkey | Caucasians | 43/43/105 | 26/17/0 | 24/19/0 | 49/44/12 | 0.332/0.659 | 7 |
6 | Wu, 2011 [28] | China (Tianjin) | Asians | 56/56/50 | 5/25/26 | 13/25/18 | 9/22/19 | 0.771/0.556 | 7 |
7 | Jing, 2011 [18] | China (Jiangsu) | Asians | 416/-/416 | 50/274/92 | - | 67/212/137 | -/0.318 | 8 |
8 | Jeoh, 2013 [17] | Korea | Asians | 399/191/- | 50/349* | 28/163* | - | - | 7 |
9 | Grzegorzewska, 2014 [16] | Poland | Caucasians | -/222/437 | - | 104/97/21 | 225/177/35 | -/0.982 | 8 |
10 | Raina, 2021 [24] | India | Asians | 444/354/515 | 210/204/30 | 138/171/45 | 238/236/41 | 0.069/0.095 | 8 |
11 | Xu, 2015 [29] | China (Hubei) | Asians | 50/-/50 | 16/20/14 | - | 18/19/13 | -/0.100 | 7 |
12 | Ma, 2016 [22] | China (Zhejiang) | Asians | 208/-/209 | 66/102/40 | - | 46/93/70 | -/0.156 | 8 |
13 | Ma, 2017 [21] | China (Gansu) | Asians | 30/-/69 | 7/13/10 | - | 13/36/20 | -/0.652 | 7 |
14 | Su, 2018 [26] | China (Hebei) | Asians | 135/-/149 | 18/62/55 | - | 26/66/57 | -/0.688 | 8 |
15 | Wang, 2019 [27] | China (Jiangsu) | Asians | 52/60/78 | 18/22/12 | 10/25/25 | 30/32/16 | 0.304/0.179 | 7 |
16 | Cheng, 2019 [14] | China (Zhejiang) | Asians | 99/-/109 | 21/51/27 | - | 16/54/39 | -/0.699 | 7 |