Fig. 4

The immune landscape in distinct m6A modification patterns. A Heatmap of subtype-specific upregulated and downregulated biomarkers using limma for 4 identified subtypes in TCGA-THCA cohort; B GSVA of subtype-specific upregulated pathways (left). GSVA of subtype-specific downregulated pathways in TCGA-THCA cohort (right); C Boxplot showing the different m6aScore between m6A subtypes. ANOVA test: The asterisks represented the statistical p value (*p <0.05; **p <0.01; ***p <0.001); D Scatterplot with marginal distributions overlaid on the axes and results from statistical tests in the subtitle for m6ascore and cnv aneuploid score