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Table 4 Association between AISI and TNs in all participants and stratified by gender

From: Association of systemic immune-inflammation index (SII) and aggregate index of systemic inflammation (AISI) with thyroid nodules in patients with type 2 diabetes mellitus: a retrospective study

 

Quartiles 1

Quartiles 2

Quartiles 3

Quartiles 4

P for trend

Total

69.7

128.9

188.7

358.6

 

Cases/participants

45/92

52/93

60/93

72/92

 

Model 1

1.0

1.325(0.743 ~ 2.362)

1.899(1.053 ~ 3.424)

3.760(1.978 ~ 7.147)

< 0.001

Model 2

1.0

1.589(0.839 ~ 3.008)

1.720(0.895 ~ 3.305)

3.257(1.602 ~ 6.622)

0.001

Model 3

1.0

1.594(0.839 ~ 3.028)

1.714(0.889 ~ 3.306)

3.238(1.584 ~ 6.617)

0.002

Men

77.1

126.1

178.1

317.7

 

Cases/participants

15/52

25/53

27/53

38/52

 

Model 1

1.0

2.202(0.983 ~ 4.934)

2.562(1.144 ~ 5.736)

6.695(2.840 ~ 15.783)

< 0.001

Model 2

1.0

2.298(0.953 ~ 5.539)

2.442(1.016 ~ 5.868)

6.884(2.702 ~ 17.542)

< 0.001

Model 3

1.0

2.530(1.023 ~ 6.260)

2.473(0.999 ~ 6.125)

8.573(3.175 ~ 23.148)

< 0.001

Women

64.9

132.4

204.1

430.6

 

Cases/participants

30/41

18/25

34/43

42/51

 

Model 1

1.0

0.879(0.324 ~ 2.381)

1.148(0.409 ~ 3.219)

1.889(0.613 ~ 5.818)

0.189

Model 2

1.0

1.037(0.334 ~ 3.219)

1.095(0.341 ~ 3.518)

1.440(0.399 ~ 5.196)

0.549

Model 3

1.0

0.901(0.280 ~ 2.900)

1.043(0.310 ~ 3.506)

1.356(0.360 ~ 5.111)

0.572

  1. Model 1, unadjusted
  2. Model 2, adjusted for age, duration of diabetes, DN, TT3, FT3, TSH, TT4, FT4
  3. Model 3, further adjusted for Homa-ir, FPG, HbA1c based on model 2