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Table 3 Association between SII and TNs in all participants and stratified by gender

From: Association of systemic immune-inflammation index (SII) and aggregate index of systemic inflammation (AISI) with thyroid nodules in patients with type 2 diabetes mellitus: a retrospective study

 

Quartiles 1

Quartiles 2

Quartiles 3

Quartiles 4

P for trend

Total

231.8

343.6

480.3

781.0

 

Cases/participants

43/92

54/93

62/93

70/92

 

Model 1

1.0

1.578(0.883 ~ 2.820)

2.279(1.257 ~ 4.131)

3.626(1.931 ~ 6.810)

< 0.001

Model 2

1.0

1.373(0.726 ~ 2.594)

2.055(1.072 ~ 3.938)

2.415(1.195 ~ 4.880)

0.011

Model 3

1.0

1.366(0.723 ~ 2.579)

2.144(1.119 ~ 4.108)

2.457(1.212 ~ 4.983)

0.009

Men

236.1

328.3

440.2

696.8

 

Cases/participants

15/52

27/53

29/53

34/52

 

Model 1

1.0

2.562(1.144 ~ 5.736)

2.981(1.329 ~ 6.685)

4.659(2.035 ~ 10.669)

0.001

Model 2

1.0

2.195(0.913·5.278)

2.600(1.088 ~ 6.212)

3.518(1.420 ~ 8.716)

0.013

Model 3

1.0

1.900(0.781 ~ 4.619)

2.840(1.180 ~ 6.833)

3.861(1.526 ~ 9.770)

0.006

Women

226.7

370.1

561.9

975.8

 

Cases/participants

27/40

31/40

35/40

31/40

 

Model 1

1.0

1.658(0.614 ~ 4.482)

3.370(1.070 ~ 10.613)

1.658(0.614 ~ 4.482)

0.369

Model 2

1.0

1.259(0.409 ~ 3.879)

3.617(0.930 ~ 14.066)

0.974(0.285 ~ 3.325)

0.970

Model 3

1.0

1.107(0.346 ~ 3.539)

3.701(0.924 ~ 14.820)

0.881(0.245 ~ 3.174)

0.969

  1. Model 1, unadjusted
  2. Model 2, adjusted for age, duration of diabetes, DN, TT3, FT3, TSH, TT4, FT4
  3. Model 3, further adjusted for Homa-ir, FPG, HbA1c based on model 2