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Table 2 Univariate binary logistic regression for thyroid nodules

From: Association of systemic immune-inflammation index (SII) and aggregate index of systemic inflammation (AISI) with thyroid nodules in patients with type 2 diabetes mellitus: a retrospective study

 

Total

 

Male

 

Female

P values

OR (95%CI)

P values

OR (95%CI)

P values

OR (95%CI)

Age(y)

1.057(1.039 ~ 1.076)

< 0.001

1.036(1.014 ~ 1.058)

0.001

1.075(1.039 ~ 1.111)

< 0.001

Duration of diabetes(y)

1.049(1.022 ~ 1.076)

< 0.001

1.030(0.997 ~ 1.064)

0.073

1.054(1.006 ~ 1.105)

0.027

DN, n (%)

1.812()1.178 ~ 2.786

0.007

2.642(1.513 ~ 4.612)

0.001

1.444(0.663 ~ 3.149)

0.355

SII

1.002(1.001 ~ 1.003)

< 0.001

1.003(1.002 ~ 1.005)

< 0.001

1.001(1.000 ~ 1.002)

0.226

AISI

1.004()1.002 ~ 1.006

< 0.001

1.006(1.003 ~ 1.010)

< 0.001

1.002(0.999 ~ 1.004)

0.127

TT3(ng/ml)

0.272(0.085 ~ 0.872)

0.029

0.251(0.058 ~ 1.091)

0.065

0.574(0.067 ~ 4.906)

0.612

FT3 (pg/mL)

0.518(0.334 ~ 0.804)

0.003

0.607(0.349 ~ 1.058)

0.078

0.605(0.274 ~ 1.339)

0.215

TSH (uIU/ml)

1.113(0.915 ~ 1.353)

0.284

1.091(0.835 ~ 1.426)

0.521

0.956(0.700 ~ 1.307)

0.778

TT4 (ug/dL)

1.158(1.018 ~ 1.318)

0.026

1.127(0.949 ~ 1.339)

0.174

1.071(0.861 ~ 1.332)

0.538

FT4 (ng/dL)

0.572(0.138 ~ 2.379)

0.443

0.335(0.055 ~ 2.032)

0.235

2.681(0.181 ~ 39.797)

0.474

eGFR(ml/min)

0981(0.973 ~ 0.990)

< 0.001

0.983(0.973 ~ 0.993)

0.001

0.980(0.964 ~ 0.996)

0.014

Scr (umol/L)

1.003(1.000 ~ 1.006)

0.073

1.006(1.000 ~ 1.012)

0.040

1.002(0.997 ~ 1.006)

0.528

BUN (mmol/L)

1.058(1.000 ~ 1.120)

0.050

1.078(0.999 ~ 1.164)

0.053

1.034(0.943 ~ 1.133)

0.483

HOMA-IR

1.009(0.994 ~ 1.025)

0.259

1.009(0.992 ~ 1.027)

0.296

1.009(0.977 ~ 1.042)

0.582

  1. Note: Variables were calculated using the univariate binary logistic regression model. The effect of each variable on thyroid nodules was presented in odds ratio and 95% confidence interval. Odds ratio greater than 1 represented increased odds for thyroid nodules. P values were calculated using univariate binary logistic regression analysis
  2. Abbreviations: SII, systemic immune-inflammation index; AISI, aggregate index of systemic inflammation; TT3, total Triiodothyronine; FT3, free triiodothyronine; TSH, thyroid stimulating hormone; TT4, total thyroxine; FT4, free thyroxine; Scr, serum creatinine; eGFR, estimated glomerular filtration rate; BUN, blood urea nitrogen; HOMA-IR, (fasting insulin × fasting glucose)/405 with glucose measured in mg/dL and insulin in µU/L.