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Fig. 3 | BMC Endocrine Disorders

Fig. 3

From: Unilateral adrenalectomy for a drug-resistant bilateral primary aldosteronism with heart failure: pathophysiology and surgical indication

Fig. 3

Expression analysis of SF-1. Expression analysis of SF-1 mRNA by RT-PCR (A) and of SF-1 protein by IHC (B and C) in controls (tissue from patients with aldosterone-producing adenoma, n = 3) and in tissue from the subject of the present case report. SF-1 mRNA levels were significantly higher in the present case than in the controls (A). Statistical analysis was performed with the Mann-Whitney U test. In IHC, nuclear staining was nominally higher in the present case (B) than in the controls (C). IHC: immunohistochemical staining, RT-PCR: reverse transcription-polymerase chain reaction, SF-1: steroidogenic factor 1

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