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Table 4 Baseline and stimulated IPS/P ratio for ACTH and Prolactin in the studied patients

From: Bilateral inferior petrosal sinus sampling: validity, diagnostic accuracy in lateralization of pituitary microadenoma, and treatment in eleven patients with Cushing’s syndrome – a single-center retrospective cohort study

Case

Number

Diagnosis

Baseline IPS/P ACTH

(≥ 2)

Stimulated IPS/P ACTH (≥ 3)

Stimulated IPS/P prolactin (≥ 1.8)

IPS/P ACTH / IPS/P prolactin (≥ 1.3)

Inter-sinus ratio

(≥ 1.4)

lateralization

  

R

L

R

L

R

L

R

L

Baseline

stimulated

 

1

CD

5.45

1.15

14.81

1.50

2.04

1.80

7.26

0.83

4.74

9.87

Right

2

CD

0.45

1.44

1.11

4.52

2.68

1.85

0.41

2.44

3.20

4.07

Left

3

CD

20.14

1.08

20.27

0.97

6.24

1.83

3.25

0.53

18.65

20.90

Right

4

CD

3.71

3.37

73.36

14

4.82

5.65

15.22

2.48

1.10

5.24

Right

5

CD

11.21

5.86

36.98

6.51

2.96

3.2

12.49

2.03

1.91

5.68

Right

6

CD

6.52

23.54

13.81

24.86

4.23

3.92

3.26

6.34

3.61

1.80

Left

7

Recurrent CD

4.77

1.11

9.33

1.15

2.02

1.95

4.62

0.59

4.30

8.11

Right

8

Recurrent CD

1.48

24.7

4.08

24

7.8

2.44

0.52

9.84

16.69

5.88

Left

9

EAS

0.96

0.87

1.27

1.18

2.29

9.21

0.55

0.13

1.10

1.08

Equivocal

10

EAS

1.16

1.13

1.40

1.37

5.28

5.09

0.26

0.27

1.03

1.02

Equivocal

11

EAS

1.21

1.16

1.40

1.27

3.43

3.43

0.41

0.37

1.04

1.10

Equivocal

  1. IPS: inferior petrosal sinus; P: peripheral; ACTH: adrenocorticotropic hormone; CD: Cushing’s disease; EAS: ectopic ACTH syndrome