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Table 2 Clinical manifestations of the studied patients

From: Bilateral inferior petrosal sinus sampling: validity, diagnostic accuracy in lateralization of pituitary microadenoma, and treatment in eleven patients with Cushing’s syndrome – a single-center retrospective cohort study

Case number

Lag Period (months)*

Manifestation

1

6

weight gain, oligomenorrhea, hirsutism, striae, HTN, headache

2

5

weight gain, oligomenorrhea, acne, striae, HTN

3

8

weight gain, acne, hirsutism, striae, proximal muscle weakness, HTN, headache

4

6

weight gain, oligomenorrhea, infertility, hair loss, acne, hirsutism, striae, HTN

5

4

weight gain, oligomenorrhea, acne, striae, mild edema, HTN

6

12

oligomenorrhea, hirsutism, easy bruising, proximal muscle weakness, HTN

7

8

loss of libido, HTN, headache

8

12

oligomenorrhea, hirsutism, striae, proximal muscle weakness

9

4

weight gain, impotency, Hyper

pigmentation, striae, acne, easy bruising, HTN

10

12

weight gain, facial edema, bone pain, proximal muscle weakness, HTN

11

3

weight gain, oligomenorrhea, hirsutism, hyper

pigmentation, proximal muscle weakness

  1. *Lag period: the gap between the onset of clinical symptoms and confirmation of the disease; HTN: hypertension