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Table 3 Characteristics of studies included in the systematic review and meta-analysis

From: Comparing the effectiveness of metformin with lifestyle modification for the primary prevention of type II diabetes: a systematic review and meta-analysis

Author

Study

Year of start study

Primary outcome

Country

Follow-up (year)

Sample size

Male

baseline

Age baseline

Mean ± SD

BMI

Baseline Mean ± SD

FPG

Baseline Mean ± SD

BMI

After intervention

MD ± SD

FPG

After intervention

MD ± SD

Knowler, W. C. [10]

DPP

1999

Diabetes incidence

USA

2.8

2152

708

50.6 ± 10.7

34 ± 6.7

106.5 ± 8.3

- 1.45 ± 1.96

- 0.76 ± 11.84

Ramachandran, A. [11]

IDPP1

2002

Diabetes incidence

India

3

266

211

45.9 ± 5.8

25.8 ± 3.5

97 ± 0.75

Not reported

Not reported

Weber, M

B. [13]

D-CLIP

2012

Diabetes incidence

India

2.54

576

364

44.4 ± 9.3

27.9 ± 3.7

102.3 ± 0.5

Not reported

Not reported

Lu, Y. H. [12]

2005

Diabetes incidence

China

2

181

95

63.5 ± 6.9

27 ± 3.5

106.9 ± 0.47

26.67 ± 3.66

5.99 ± 0.88

O'Brien, M. J. [14] PREVEN T-DM

 

Weight

USA

1

62

0

45.6 ± 12

33.8 ± 6.9

96.1 ± 8.8

- 1.2

0.83

  1. SD Standard deviation