Table 4 Clinical characteristics and islet function indexes of LADA-1 subjects according to RDW tertiles
I(11.2–12.4%) | II(12.5–12.9%) | III(13.0–18%) | P | |
|---|---|---|---|---|
n | 46 | 46 | 44 | |
male (%) | 24 | 22 | 20 | 0.323 |
Age (years) | 57.3 ± 15.6#Δ | 58.8 ± 16.8*Δ | 61.2 ± 16.4*# | 0.037 |
duration(years) | 5.8 ± 3.5#Δ | 6.8 ± 3.6*Δ | 7.0 ± 3.8*# | 0.027 |
BMI (kg/m2) | 19.1 ± 3.4 | 19.6 ± 3.5 | 19.5 ± 3.6 | 0.676 |
SBP (mmHg) | 126.9 ± 16.5 | 128.9 ± 15.9 | 127.9 ± 16.7 | 0.351 |
DBP (mmHg) | 69.1 ± 16.3 | 70.9 ± 15.8 | 71.4 ± 16.5 | 0.092 |
TG (mmol/L) | 1.2 ± 0.5 | 1.4 ± 0.6 | 1.4 ± 0.6 | 0.479 |
TC (mmol/L) | 4.34 ± 0.74 | 4.02 ± 0.59 | 4.46 ± 0.76 | 0.294 |
LDL (mmol/L) | 2.6 ± 0.4 | 2.4 ± 0.5 | 2.8 ± 0.6 | 0.531 |
HDL (mmol/L) | 1.1 ± 0.3 | 1.0 ± 0.3 | 0.9 ± 0.4 | 0.072 |
GAD(IU/ml) | 278.4 ± 54.2 | 273.0 ± 57.4 | 264.5 ± 55.9 | 0.095 |
ALT (U/L) | 18.8 ± 11.9 | 21.1 ± 11.7 | 19.1 ± 10.9 | 0.413 |
AST (U/L) | 18.7 ± 12.1 | 21.4 ± 12.9 | 19.3 ± 11.8 | 0.349 |
Cr (umol/L) | 63.5 ± 29.3#Δ | 64.8 ± 28.7*Δ | 66.3 ± 29.6*# | 0.044 |
SUA (umol/L) | 318.8 ± 140.2 | 329.6 ± 139.7 | 324.2 ± 141.8 | 0.278 |
HbA1c(%) | 9.5 ± 2.2 | 9.4 ± 2.3 | 9.3 ± 2.3 | 0.072 |
FCP (ng/ml) | 0.8 ± 0.4#Δ | 0.9 ± 0.5*Δ | 1.1 ± 0.7*# | < 0.001 |
P2hCP (ng/ml) | 1.6 ± 0.5 | 1.8 ± 0.6 | 1.8 ± 0.6 | 0.064 |
Use of insulin(%) | 29(63.0%) | 30(65.2%) | 29(65.9%) | 0.164 |
HOMA-IR | 1.6 ± 0.5 | 1.5 ± 0.5 | 1.6 ± 0.5 | 0.315 |
HOMA-β | 10.4 ± 5.2Δ | 11.19 ± 4.9 | 11.29 ± 5.2* | 0.082 |