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Table 3 Differentially abundant bacteria — pre-T2D and T2D vs. healthy, LUMI-Seq™

From: Exploring the gut microbiota in patients with pre-diabetes and treatment naïve diabetes type 2 - a pilot study

Groups

Phylum

Class

Bacterial taxa

Log2Fold Changea

p adj

Pre-T2D vs. healthy

Bacillota (Firmicutes)

Bacilli

Bacilli

1.84

2.42E-04

Lactobacillales

1.90

2.42E-04

Streptococcaceae

1.76

4.03E-04

Streptococcus

1.92

2.42E-04

Clostridia

Eisenbergiella

1.86

1.20E-03

Eisenbergiella massiliensis

1.43

1.25E-02

Neglecta

1.35

4.03E-04

Neglecta timonensis

1.35

4.03E-04

Oscillibacter valericigenes

-0.77

3.26E-02

Bacteroidota (Bacteroidetes)

Bacteroidia

Bacteroides coprocola

-23.36

2.90E-17

T2D vs. healthy

Bacillota (Firmicutes)

Clostridia

Dorea

1.16

1.22E-02

Dorea formicigenerans

0.89

3.14E-02

Dorea longicatena

1.03

2.34E-02

Anaerotignum

-0.99

3.14E-02

Erysipelotrichia

Erysipelotrichia

1.05

1.91E-02

Erysipelotrichales

1.05

1.91E-02

Erysipelotrichaceae

1.05

1.91E-02

Turicibacter

0.71

3.56E-02

Turicibacter sanguinis

0.71

3.56E-02

  1. Bacterial taxa with significantly different abundance (adjusted p < 0.05) when comparing the groups pre-T2D (n = 22) and healthy (n = 48), or T2D (n = 16) and healthy (n = 48), based on the LUMI-Seq™ data
  2. aIncreased or decreased abundance, in pre-T2D (vs. healthy), or in T2D (vs. healthy)