Exploring the gut microbiota in patients with pre-diabetes and treatment naïve diabetes type 2 - a pilot study

BMC Endocrine Disorders

Table 2 Differentially abundant bacteria – pre-T2D vs. healthy, GA-map® 131-plex

Groups	Phylum	Class	Bacterial marker	I/D^a	p adj
Pre-T2D vs. healthy	Bacillota (Firmicutes)	Clostridia	Dorea spp.	I	9.30E-02
			Roseburia sp.	D	9.30E-02
			Roseburia intestinalis	D	9.30E-02
			Faecalibacterium prausnitzii	D	3.90E-02
		Negativicutes	Dialister invisus	D	9.30E-02
		Negativicutes	Veillonella spp.	D	8.20E-02
	Pseudomonadota (Proteobacteria)	(Phylum marker)	Pseudomonadota	I	2.00E-02
		Gammaproteobacteria	Enterobacterales	I	3.20E-02
		Gammaproteobacteria	Shigella spp. & Escherichia spp.	I	6.90E-02
		Betaproteobacteria	Sutterella wadsworthensis	D	9.30E-02

Bacterial markers with significantly different abundance (adjusted p < 0.1) when comparing the groups pre-T2D (n = 22) and healthy (n = 38), based on the GA-map® 131-plex data
^aIncreased (I) or decreased (D) abundance, in pre-T2D (vs. healthy)

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