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Table 1 Anthropometric characteristics and erythrocyte and reticulocyte parameters of obesity and body shape phenotypes

From: Associations of obesity and body shape with erythrocyte and reticulocyte parameters in the UK Biobank cohort

 

NORMAL WEIGHT

OVERWEIGHT

OBESE

 

Pear

Apple

Pear

Apple

Pear

Apple

WOMEN

 Cohort: n (% sex)

14,886 (14.1)

8357 (7.9)

9530 (9.0)

9724 (9.2)

4094 (3.9)

4217 (4.0)

 Age (years)

54.2 (7.9)

56.0 (7.9)

55.4 (7.9)

56.8 (7.6)

54.8 (7.9)

55.6 (7.8)

 BMI (kg/m2)

22.6 (1.6)

22.9 (1.5)

27.0 (1.4)

27.2 (1.4)

33.8 (3.4)

32.9 (2.6)

 ABSI

69.7 (2.3)

76.7 (3.2)

69.6 (2.5)

77.1 (3.1)

69.7 (2.6)

77.1 (3.1)

 HI

65.8 (1.3)

62.5 (1.3)

65.8 (1.4)

62.3 (1.4)

66.2 (1.7)

62.0 (1.7)

 Erythrocytes 1012/L

4.24 (0.30)

4.28 (0.32)

4.30 (0.31)

4.37 (0.31)

4.39 (0.30)

4.44 (0.32)

 Haematocrit %

38.7 (2.6)

39.2 (2.7)

39.0 (2.6)

39.6 (2.6)

39.5 (2.6)

40.0 (2.7)

 Reticulocytes 109/L

44.8 (17.7)

50.6 (19.7)

51.8 (19.5)

60.1 (21.4)

61.6 (21.8)

68.7 (22.9)

 Reticulocyte Percent %

1.06 (0.41)

1.18 (0.45)

1.21 (0.45)

1.38 (0.49)

1.41 (0.49)

1.55 (0.51)

 Imm. Reticulocytes 109/L

12.1 (6.0)

14.3 (7.1)

14.8 (7.1)

18.0 (8.2)

19.1 (8.8)

21.9 (9.3)

 IRF %

26.5 (5.5)

27.5 (5.5)

28.0 (5.5)

29.3 (5.6)

30.2 (5.7)

31.3 (5.7)

 Haemoglobin g/L

133.0 (8.8)

134.9 (9.2)

134.2 (8.7)

136.6 (9.1)

135.8 (8.7)

137.6 (9.4)

 MCH pg

31.4 (1.7)

31.6 (1.8)

31.3 (1.7)

31.3 (1.7)

31.0 (1.7)

31.1 (1.8)

 MCHC g/L

344.0 (10.2)

344.7 (10.0)

344.2 (9.9)

345.0 (9.3)

343.8 (9.4)

344.5 (9.2)

 MCV fL

91.3 (4.2)

91.6 (4.5)

90.9 (4.2)

90.9 (4.3)

90.2 (4.2)

90.1 (4.4)

 MRV fL

105.5 (7.1)

105.5 (7.3)

105.5 (7.3)

105.0 (7.4)

105.3 (7.5)

104.6 (7.3)

 RDW %

13.4 (0.9)

13.4 (0.9)

13.5 (0.9)

13.4 (0.9)

13.6 (0.9)

13.5 (0.9)

MEN

 Cohort: n (% sex)

9471 (9.4)

3790 (3.8)

13,589 (13.5)

8394 (8.3)

4620 (4.6)

3362 (3.3)

 Age (years)

54.3 (8.3)

56.4 (7.8)

53.6 (8.1)

56.9 (7.7)

52.9 (7.8)

55.7 (7.7)

 BMI (kg/m2)

23.1 (1.4)

23.3 (1.4)

27.2 (1.4)

27.3 (1.4)

32.9 (2.8)

32.6 (2.5)

 ABSI

76.7 (2.5)

82.7 (2.3)

77.0 (2.3)

82.6 (2.1)

77.2 (2.2)

82.7 (2.2)

 HI

50.2 (0.9)

48.0 (0.9)

50.1 (0.9)

48.0 (0.9)

50.2 (1.1)

47.9 (0.9)

 Erythrocytes 1012/L

4.66 (0.34)

4.71 (0.35)

4.76 (0.33)

4.80 (0.34)

4.83 (0.33)

4.87 (0.34)

 Haematocrit %

42.7 (2.7)

43.4 (2.9)

43.3 (2.7)

43.8 (2.7)

43.9 (2.6)

44.3 (2.7)

 Reticulocytes 109/L

48.6 (19.5)

54.9 (20.7)

60.2 (22.2)

65.7 (22.5)

73.1 (24.5)

76.6 (24.7)

 Reticulocyte Percent %

1.04 (0.41)

1.17 (0.44)

1.26 (0.45)

1.37 (0.46)

1.51 (0.50)

1.57 (0.50)

 Imm. Reticulocytes 109/L

12.9 (6.5)

15.2 (7.4)

17.1 (8.0)

19.3 (8.5)

22.3 (9.7)

23.8 (10.0)

 IRF %

25.9 (5.5)

27.1 (5.5)

27.8 (5.5)

28.8 (5.5)

30.0 (5.5)

30.5 (5.5)

 Haemoglobin g/L

147.8 (9.0)

149.9 (9.6)

150.3 (8.8)

152.1 (9.1)

152.3 (8.8)

153.8 (9.2)

 MCH pg

31.8 (1.5)

31.9 (1.7)

31.6 (1.5)

31.8 (1.6)

31.6 (1.6)

31.7 (1.6)

 MCHC g/L

346.1 (9.6)

346.0 (9.3)

347.1 (10.0)

347.2 (9.6)

347.5 (9.8)

347.2 (9.1)

 MCV fL

91.8 (3.9)

92.2 (4.4)

91.2 (3.8)

91.5 (4.1)

90.8 (4.0)

91.2 (4.0)

 MRV fL

106.4 (7.1)

106.9 (7.5)

105.6 (7.1)

105.9 (7.3)

105.3 (7.1)

105.4 (7.3)

 RDW %

13.3 (0.7)

13.4 (0.7)

13.3 (0.7)

13.3 (0.7)

13.3 (0.7)

13.4 (0.7)

  1. ABSI a body shape index (cut-offs ≥ 73 for women, ≥ 80 for men); Apple large-ABSI-small-HI, BMI body mass index, HI hip index (cut-offs ≥ 64 for women, ≥ 49 for men), Imm. Reticulocytes immature reticulocytes, IRF immature reticulocyte fraction, MCH mean corpuscular haemoglobin, MCHC mean corpuscular haemoglobin concentration, MCV mean corpuscular volume, MRV mean reticulocyte volume; Normal weight – BMI ≥ 18.5 to < 25 kg/m2; Overweight – BMI ≥ 25 to < 30 kg/m2; Obese – BMI ≥ 30 to < 45 kg/m2; Pear – small-ABSI-large-HI; RDW – red cell distribution width. Values represent mean (standard deviation). Pairwise comparisons for obese-“apple” vs. normal-weight-“pear” were performed with unpaired t-test. All comparisons were significant at p < 1*10–6, except for MCHC in women (p = 0.01) and MCH (p = 1*10–4) and RDW (p = 0.002) in men