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Table 3 Associations of folate with TSH among T2DM patients, (N = 268)

From: Folate deficiency may increase the risk for elevated TSH in patients with type 2 diabetes mellitus

Variable

Unadjusted β(95% CI)

Adjusted β(95% CI)

Per 1 ng/mL increase in serum folate

-0.446 (-0.880, -0.001)

-0.062 (-0.112, -0.012)

Folate deficiency b

  

 No

Ref.

Ref.

 Yes

2.384 (1.513, 3.256)

2.444 (1.535, 3.352)

  1. Note
  2. a Adjusted for age, sex, Vitamin B12, Hcy, BMI, HDL-C, TG, SBP, DBP;
  3. b Folate deficiency was defined as serum folate concentrations < 4.4 ng/mL
  4. Abbreviations: TSH, thyroid-stimulating hormone; CI, confidence interval; Hcy, homocysteine; BMI: body mass index; HDL-C, high density liptein cholesterol; TG, Triglyceride; SBP, systolic blood pressure; DBP, diastolic blood pressure