Table 1 Characteristics for T2DM patients, (N = 268)
From: Folate deficiency may increase the risk for elevated TSH in patients with type 2 diabetes mellitus
Total participants (n = 268) | Normal TSH a (n = 227) | Elevated TSH b (n = 33) | Low TSH c (n = 8) | P | |
|---|---|---|---|---|---|
Age, Median (IQR) | 56.0 (19.5) | 55.0 (19.0) | 60.0 (16.0) | 63 (18.0) | 0.182 e |
Sex, n (%) | |||||
Men | 166 (61.9) | 148 (65.2) | 15 (45.4) | 3 (37.5) | 0.031 f |
Women | 102 (38.1) | 79 (34.8) | 18 (54.6) | 5 (62.5) | |
Folate [(ng/mL), Median (IQR)] | 9.4 (8.3) | 9.4 (8.2) | 7.9 (10.1) | 8.2 (8.4) | 0.247 e |
Folate deficiency d | |||||
No | 240 (89.6) | 211 (96.0) | 22 (66.7) | 7 (87.5) | < 0.001 f |
Yes | 28 (10.4) | 16 (7.0) | 11 (33.3) | 1 (12.5) | |
Vitamin B12 [(pg/mL), Median (IQR)] | 544.0 (436.0) | 539.0 (421.0) | 748.0 (588.4) | 466.1 (398.0) | 0.036 e |
Hcy [(µmol/L), Median (IQR)] | 11.0 (3.5) | 11.0 (4.0) | 11.0 (2.0) | 12.0 (2.5) | 0.747 e |
BMI | |||||
Underweight/ normal weight | 66 (24.6) | 59 (26.0) | 7 (21.2) | 0 (0.0) | 0.167 f |
Overweight | 124 (46.3) | 99 (43.6) | 18 (54.6) | 7 (87.5) | |
Obese | 78 (29.1) | 69 (30.4) | 8 (24.2) | 1 (12.5) | |
HDL-C [(mmol/L), Median (IQR)] | 1.1 (0.5) | 1.1 (0.5) | 1.1 (0.6) | 1.3 (0.6) | 0.714 e |
TG [(mmol/L), Median (IQR)] | 1.4 (0.8) | 1.4 (0.9) | 1.4 (1.0) | 1.2 (0.8) | 0.306 e |
SBP [mmHg, Median (IQR)] | 129.7 (19.0) | 129.4 (20.0) | 129.0 (16.0) | 140.0 (23.5) | 0.159 e |
DBP [mmHg, Median (IQR)] | 76.0 (13.0) | 76.0 (13.0) | 74.0 (8.0) | 84.5 (26.5) | 0.265 e |