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Fig. 3 | BMC Endocrine Disorders

Fig. 3

From: PIWIL2 restrains the progression of thyroid cancer via interaction with miR-146a-3p

Fig. 3

The interaction between PIWIL2 and miR-146a-3p in TC cell lines

(A) The mRNA level of PIWIL2 in TPC-1 cell lines after PIWIL2 was over-expressed or knocked down. (B) The mRNA level of miR-146a-3p in TPC-1 cell lines after PIWIL2 was over-expressed or knocked down. (C) The copy number of PIWIL2 and miR-146a in TPC-1 and KTC-3 cell lines with absolute quantification. (D) The pairing relationship between PIWIL2 and miR-146a-3p RNA sequence. E, F. The luciferase activity was tested in 293T cells co-transfected with PIWIL2 WT or PIWIL2 Mut and miR-146a-3p mimic or mimic NC. G. The RIP results. ##: P < 0.01 between groups. N = 6. TC: thyroid cancer

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