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Fig. 2 | BMC Endocrine Disorders

Fig. 2

From: Case reports of collision and composite carcinomas of the thyroid: an insight into their origin and clinical significance

Fig. 2

Pathological findings of thyroid collision carcinoma. A HE staining showed mixed presence of normal thyroid tissue (yellow arrow), papillary carcinoma (red arrow) and medullary carcinoma (black arrow) at low power, and the two cancers showed crossover (40 ×). B Papillary thyroid cancer cells were arranged in follicular shape, with increased nucleus-to-plasma ratio, ground hyaline nucleus, and nuclear furrow (red arrow). Medullary thyroid cancer cells were distributed in lamellar nests, and amyloid stroma (black arrow, 200 ×). C-F Immunohistochemical staining showed that papillary thyroid carcinoma was positive for TG (C) and CK19 (D), while medullary carcinoma was negative. On the contrary, CT (E) and CEA (F) of medullary carcinoma was positive, while papillary carcinoma was negative. (100 ×)

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BMC Endocrine Disorders

ISSN: 1472-6823

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