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Fig. 5 | BMC Endocrine Disorders

Fig. 5

From: Effects of UBE3A on the insulin resistance in polycystic ovary syndrome through the ubiquitination of AMPK

Fig. 5

AMPK knockdown reversed the role of UBE3A knockdown in the PCOS rats

After UBE3A and AMPK knockdown, the fat rate (A), glucose tolerance (B) and insulin tolerance (C) in the PCOS + IR rats. (D) The GLUT4 mRNA levels were in the PCOS + IR rats were detected by RT-qPCR. (E) The number of IR rats in each group were calculated. (F & G) The p-IRS1 and p-AKT protein levels were in the PCOS + IR rats were detected by western blot

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BMC Endocrine Disorders

ISSN: 1472-6823

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