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Table 2 The interaction between CETP Taq1B polymorphism and NEAP on cardiovascular risk factors

From: Dietary acid load and its interaction with CETP TaqB1 polymorphisms on lipid profile among patients with Type 2 diabetes mellitus

Variables

NEAP

Mean±SD

P1

P2

 

B1B1

B1B2

B2B2

Model (1)

Model (2)

P -trend

LDL (mg/dl)

T1

106.37±11.8

121.94±4.67

126.07±8.92

0.01

0.01

0.03

T2

119.71±12.61

121.19±4.86

121.5±7.86

T3

146.75±16.69

112.59±4.23

103.12±11.8

HDL (mg/dl)

T1

64.25±5.48

53.52±1.53

58.64±2.93

0.11

0.03

0.31

T2

57.87±3.87

51.44±1.59

57.66±2.58

T3

48±4.14

51.72±1.39

52±3.87

LDL/HDL

T1

1.96±3.8

2.3±1.5

2.26±2.87

<0.001

<0.001

<0.001

T2

2.6±4.06

2.4±1.56

2.14±2.53

T3

4.81±5.37

2.26±1.36

2 ±3.8

TC (mg/dl)

T1

201.5±26.78

203.39±10.6

211.84±21.01

0.04

0.03

0.19

T2

210.57±28.63

219.17±11.05

223.27±17.85

T3

299.25±37.88

204.17±9.62

201.62±26.78

TG (mg/dl)

T1

178.12±41.03

185.77±16.57

162.64±31.01

0.004

0.004

0.24

T2

193.28±43.86

186.08±17.30

185.16±27.35

T3

381.75±58.02

173.19±14.85

180.87±41.03

  1. Mean values of cardiovascular risk factors across CETP genotypes (B1B1, B1B2, B2B2) based on tertiles of NEAP intake
  2. P1 P-value for curd model, P2 P-value for the adjusted model by age, gender, physical activity, smoking, alcohol consumption, and familial history of diabetes