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Table 1 Laboratory characteristics of the patient at the time of admission

From: Combined pituitary hormone deficiency harboring CHD7 gene missense mutation without CHARGE syndrome: a case report

Hematologic characteristics

 

CPR

1.5

ng/mL

(1.0–1.6)

WBC

3,900

/µL

(3,500–9,800)

GADAb

 < 5.0

U/mL

(< 5.0)

RBC

435 × 104

/µL

(376–500)

HBsAg

0.00

IU/mL

(0.00–0.04)

Hemoglobin

13.1

g/dL

(11.3–15.2)

HCVAb

0.1

S/CO

(< 1.0)

Platelet

5.5 × 104

/µL

(13.0–36.9)

AMA2

 < 1.5

 

(< 7)

Biochemical characteristics

 

ANA

20

 

(< 40)

Total cholesterol

161

mg/dL

(139–220)

Iron

103

µg/dL

(40–188)

Triglycerides

113

mg/dL

(36–149)

TIBC

265

µg/dL

(246–410)

HDL-C

48

mg/dL

(40–87)

Ferritin

121

ng/mL

(5–152)

LDL-C

88

mg/dL

(59–139)

Ceruloplasmin

25

mg/dL

(21–37)

Urea nitrogen

9.7

mg/dL

(8.4–20.4)

M2BPGi

4.27

 

(< 1.0)

Creatinine

0.50

mg/dL

(0.40–0.74)

4C7S

12.2

ng/mL

(< 4.4)

eGFR

112.2

mL/min/1.73 m2

Endocrinological characteristics

 

Total protein

6.7

g/dL

(6.7–8.2)

LH

 < 0.10

mIU/mL

 

Albumin

3.6

g/dL

(4.0–4.8)

FSH

 < 0.10

mIU/mL

 

Total bilirubin

2.0

mg/dL

(0.2–1.2)

Estradiol

24.0

pg/mL

 

AST

43

U/L

(10–33)

Growth hormone

 < 0.03

ng/mL

(0.13–9.88)

ALT

22

U/L

(6–35)

IGF-1

 < 7

ng/mL

(119–283)

ALP

100

U/L

(38–113)

TSH

5.18

µU/mL

(0.61–4.23)

γ-GTP

152

U/L

(8–60)

FT3

1.33

pg/mL

(1.68–3.67)

PT

54.9

%

(70–120)

FT4

0.63

ng/dL

(0.7–1.48)

APTT

38.4

sec

(23.0–39.0)

ACTH

28.8

pg/mL

(7.2–63.3)

Uric acid

3.9

mg/dL

(2.2–6.7)

Cortisol

5.0

µg/dL

(3.7–19.4)

Sodium

142

mEq/L

(135–147)

DHEA-S

33

µg/dL

(58–327)

Potassium

3.6

mEq/L

(3.6–5.0)

Prolactin

12.60

ng/mL

(6.12–30.54)

Chloride

105

mEq/L

(98–108)

Urinalysis findings

 

Calcium

8.8

mg/dL

(8.8–10.2)

U-CPR

172

µg/day

(29.2–167)

FPG

115

mg/dL

(70–110)

U-Albumin

9

mg/day

(< 30)

Hemoglobin A1c

9.7

%

(4.6–6.2)

U-Copper

13.5

µg/day

(2.5–20.0)

IRI

10.6

µU/mL

(5–10)

U-Cortisol

27.6

µg/day

(5.5–66.7)

  1. Reference ranges are shown in parentheses
  2. WBC white blood cell count, RBC red blood cell count, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, eGFR estimated glomerular filtration rate, AST aspartate aminotransferase, ALT alanine aminotransferase, ALP alkaline phosphatase, γ-GTP γ-glutamyl transpeptidase, PT prothrombin time, APTT activated partial thromboplastin time, FPG fasting plasma glucose, IRI immunoreactive insulin, CPR C-peptide immunoreactivity, GADAb anti-glutamic acid decarboxylase antibody, HBsAg hepatitis B surface antigen, HCVAb hepatitis C virus antibody, AMA2 anti-mitochondrial M2 antibody, ANA antinuclear antibody, TIBC total iron binding capacity, M2BPGi Mac-2 binding protein glycosylated isomers, 4C7S type IV collagen 7S, LH luteinizing hormone, FSH follicle-stimulating hormone, IGF-1 insulin-like growth factor-1, TSH thyroid-stimulating hormone, FT3 free 3,5,3′-triiodothyronine, FT4 free thyroxine, ACTH adrenocorticotropic hormone, DHEA-S dehydroepiandrosterone sulfate