Table 4 The relationship between TD and efficacy of Peg-IFNα
Hyperthyroidism/subclinical hyperthyroidism | Hypothyroidism/subclinical hypothyroidism | p value | |
|---|---|---|---|
HBsAg seroclearance rate in 24 weeks | 12.9% (8/62) | 7% (3/43) | 0.525 |
Rate of decreasing in HBsAg levels > 1log in 24 weeks | 40.7% (22/54) | 15% (6/40) | 0.007 |
HBeAg seroclearance rate in 24 weeks | 21.7% (5/23) | 31.6% (6/19) | 0.712 |
HBsAg seroclearance rate in 48 weeks | 37.9% (11/29) | 5.7% (2/35) | 0.001 |
Rate of decreasing in HBsAg levels > 1log in 48 weeks | 52.6% (10/19) | 27.2% (9/33) | 0.067 |
HBeAg seroclearance rate in 48 weeks | 55.5% (5/9) | 47.4% (9/19) | 1 |