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Table 1 Demographic characteristics of patients with ATC

From: Comparison of the cox regression to machine learning in predicting the survival of anaplastic thyroid carcinoma

 

Overall (N = 730)

Trainingset (N = 510)

Testset (N = 220)

P-value

Age

    

 < 60

190 (26.0%)

142 (27.8%)

48 (21.8%)

0.527

 60–79

155 (21.2%)

262 (51.4%)

123 (55.9%)

 

 80

385 (52.7%)

106 (20.8%)

49 (22.3%)

 

Sex

    

 Female

441 (60.4%)

299 (58.6%)

142 (64.5%)

0.364

 Male

289 (39.6%)

211 (41.4%)

78 (35.5%)

 

Race

    

 White

580 (79.5%)

395 (77.5%)

185 (84.1%)

< 0.001

 Black

65 (8.9%)

50 (9.8%)

15 (6.8%)

 

 Other

85 (11.6%)

65 (12.7%)

20 (9.1%)

 

Marital.status

    

 Married

415 (56.8%)

286 (56.1%)

129 (58.6%)

0.612

 Widowed

148 (20.3%)

105 (20.6%)

43 (19.5%)

 

 Single

103 (14.1%)

72 (14.1%)

31 (14.1%)

 

 Divorced or separated

64 (8.8%)

47 (9.2%)

17 (7.7%)

 

Insurance

    

 Insured and any medical

714 (97.8%)

496 (97.3%)

218 (99.1%)

0.098

 Uninsured

16 (2.2%)

14 (2.7%)

2 (0.9%)

 

No.high.school.diploma

    

 < 21%

552 (75.6%)

378 (74.1%)

174 (79.1%)

0.006

 21%

178 (24.4%)

132 (25.9%)

46 (20.9%)

 

Families.below.poverty

    

 < 14%

492 (67.4%)

340 (66.7%)

152 (69.1%)

0.197

 14%

238 (32.6%)

170 (33.3%)

68 (30.9%)

 

AJCC.T.8th

    

 T1-2

29 (4.0%)

18 (3.5%)

11 (5.0%)

0.449

 T3

91 (12.5%)

64 (12.5%)

27 (12.3%)

 

 T4

610 (83.6%)

428 (83.9%)

182 (82.7%)

 

AJCC.N.8th

    

 N0

299 (41.0%)

205 (40.2%)

94 (42.7%)

0.461

 N1

431 (59.0%)

305 (59.8%)

126 (57.3%)

 

AJCC.M.8th

    

 M0

400 (54.8%)

277 (54.3%)

123 (55.9%)

0.105

 M1

330 (45.2%)

233 (45.7%)

97 (44.1%)

 

Tumor.size

    

 < 6 cm

304 (41.6%)

218 (42.7%)

86 (39.1%)

1

 6 cm

426 (58.4%)

292 (57.3%)

134 (60.9%)

 

Multifocality

    

 Multifocal

570 (78.1%)

393 (77.1%)

177 (80.5%)

0.77

 Unifocal

160 (21.9%)

117 (22.9%)

43 (19.5%)

 

Reg.LN.Sur

    

 None

490 (67.1%)

334 (65.5%)

156 (70.9%)

0.95

 1 to 3 removed

89 (12.2%)

67 (13.1%)

22 (10.0%)

 

 4 or more removed

109 (14.9%)

79 (15.5%)

30 (13.6%)

 

 Biopsy or aspiration

42 (5.8%)

30 (5.9%)

12 (5.5%)

 

Surgery

    

 None surgery

345 (47.3%)

237 (46.5%)

108 (49.1%)

0.705

 Lobectomy

138 (18.9%)

94 (18.4%)

44 (20.0%)

 

 Total/near total thyroidectomy

247 (33.8%)

179 (35.1%)

68 (30.9%)

 

Radiotherapy

    

 No

449 (61.5%)

318 (62.4%)

131 (59.5%)

1

 Yes

281 (38.5%)

192 (37.6%)

89 (40.5%)

 

Chemotherapy

    

 No/Unknown

354 (48.5%)

256 (50.2%)

98 (44.5%)

0.09

 Yes

376 (51.5%)

254 (49.8%)

122 (55.5%)

 
  1. Note: *Other include American indian/Alaska native, Asian or Pacific islander
  2. Abbreviations: SEER: Surveillance, Epidemiology, and End Results database; ATC: anaplastic thyroid carcinoma; Reg.LN.Sur: Regional lymph node surgery